Lipidomic Alterations in the Mitochondria of Aged Parkin Null Mice Relevant to Autophagy

Ellagic acid protects from myelin-associated sphingolipid loss in experimental autoimmune encephalomyelitis

(2018) Rebeca Busto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Basal mitophagy is widespread inDrosophilabut minimally affected by loss of Pink1 or parkin

(2018) Juliette J. Lee et al.   JOURNAL OF CELL BIOLOGY

ER Lipid Defects in Neuropeptidergic Neurons Impair Sleep Patterns in Parkinson’s Disease

(2018) Jorge S. Valadas et al.   NEURON

Cardiolipin exposure on the outer mitochondrial membrane modulates α-synuclein

(2018) Tammy Ryan et al.   Nature Communications

Phosphatidylglycerol Incorporates into Cardiolipin to Improve Mitochondrial Activity and Inhibits Inflammation

(2018) Wei-Wei Chen et al.   Scientific Reports

Deficiency of parkin and PINK1 impairs age-dependent mitophagy in Drosophila

(2018) Tom Cornelissen et al.   eLife

A novel regulator of autophagosome biogenesis and lipid droplet dynamics

(2018) Etienne Morel et al.   EMBO REPORTS

Lipid profiling of parkin -mutant human skin fibroblasts

(2017) Simona Lobasso et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The Journey of the Autophagosome through Mammalian Cell Organelles and Membranes

(2017) Diana Molino et al.   JOURNAL OF MOLECULAR BIOLOGY

The two-century journey of Parkinson disease research

(2017) Serge Przedborski   NATURE REVIEWS NEUROSCIENCE

Human Atg8-cardiolipin interactions in mitophagy: Specific properties of LC3B, GABARAPL2 and GABARAP

(2016) Zuriñe Antón et al.   Autophagy

Specific degradation of phosphatidylglycerol is necessary for proper mitochondrial morphology and function

(2016) Lucia Pokorná et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mitochondrial lipids in neurodegeneration

(2016) Andreas Aufschnaiter et al.   CELL AND TISSUE RESEARCH

Parkin promotes proteasomal degradation of p62: implication of selective vulnerability of neuronal cells in the pathogenesis of Parkinson’s disease

(2016) Pingping Song et al.   Protein & Cell

Elimination of paternal mitochondria in mouse embryos occurs through autophagic degradation dependent on PARKIN and MUL1

(2016) Rebecca Rojansky et al.   eLife

How lipids modulate mitochondrial protein import

(2015) Lena Böttinger et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Endogenous Parkin Preserves Dopaminergic Substantia Nigral Neurons following Mitochondrial DNA Mutagenic Stress

(2015) Alicia M. Pickrell et al.   NEURON

Lipidation of Atg8: How is substrate specificity determined without a canonical E3 enzyme?

(2014) Hitoshi Nakatogawa et al.   Autophagy

SREBF1links lipogenesis to mitophagy and sporadic Parkinson disease

(2014) Rachael M Ivatt et al.   Autophagy

Comparative Gene Identification-58 (CGI-58) Promotes Autophagy as a Putative Lysophosphatidylglycerol Acyltransferase

(2014) Jun Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome-wide RNAi screen identifies the Parkinson disease GWAS risk locus SREBF1 as a regulator of mitophagy

(2014) R. M. Ivatt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The E3 ligase PARC mediates the degradation of cytosolic cytochrome c to promote survival in neurons and cancer cells

(2014) V. Gama et al.   Science Signaling

Mitochondria directly donate their membrane to form autophagosomes during a novel mechanism of parkin-associated mitophagy

(2014) Katherine L Cook et al.   Cell and Bioscience

Quantitative profile of lipid classes in blood by normal phase chromatography with evaporative light scattering detector: Application in the detection of lipid class abnormalities in liver cirrhosis

(2013) Laura Chamorro et al.   CLINICA CHIMICA ACTA

Shorthand notation for lipid structures derived from mass spectrometry

(2013) Gerhard Liebisch et al.   JOURNAL OF LIPID RESEARCH

Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells

(2013) Charleen T. Chu et al.   NATURE CELL BIOLOGY

Dietary lipids and aging compromise chaperone-mediated autophagy by similar mechanisms

(2012) Jose Antonio Rodriguez-Navarro et al.   Autophagy

Phosphatidylserine Decarboxylase 1 (Psd1) Promotes Mitochondrial Fusion by Regulating the Biophysical Properties of the Mitochondrial Membrane and Alternative Topogenesis of Mitochondrial Genome Maintenance Protein 1 (Mgm1)

(2012) Eliana Y. L. Chan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy

(2012) R David Sentelle et al.   Nature Chemical Biology

Inhibitory effect of dietary lipids on chaperone-mediated autophagy

(2012) J. A. Rodriguez-Navarro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Parkin Mediates Proteasome-dependent Protein Degradation and Rupture of the Outer Mitochondrial Membrane

(2011) Saori R. Yoshii et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Parkin reinvents itself to regulate fatty acid metabolism by tagging CD36

(2011) Nada A. Abumrad et al.   JOURNAL OF CLINICAL INVESTIGATION

Parkin is a lipid-responsive regulator of fat uptake in mice and mutant human cells

(2011) Kye-Young Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

The PINK1/Parkin-mediated mitophagy is compromised by PD-associated mutations

(2010) Sven Geisler et al.   Autophagy

Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits

(2010) Dun-Sheng Yang et al.   BRAIN

Mitochondria Supply Membranes for Autophagosome Biogenesis during Starvation

(2010) Dale W. Hailey et al.   CELL

Cardiolipin Remodeling by ALCAT1 Links Oxidative Stress and Mitochondrial Dysfunction to Obesity

(2010) Jia Li et al.   Cell Metabolism

Altered lipid content inhibits autophagic vesicular fusion

(2010) Hiroshi Koga et al.   FASEB JOURNAL

Autophagy and lipids: tightening the knot

(2010) Jose Antonio Rodriguez-Navarro et al.   Seminars in Immunopathology

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

(2010) Derek P. Narendra et al.   PLOS BIOLOGY

Parkin-induced mitophagy in the pathogenesis of Parkinson disease

(2009) Derek Narendra et al.   Autophagy

Fatty acid 2-Hydroxylation in mammalian sphingolipid biology

(2009) Hiroko Hama   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Effects of partial suppression of parkin on huntingtin mutant R6/1 mice

(2009) Isabel Rubio et al.   BRAIN RESEARCH

The effects of parkin suppression on the behaviour, amyloid processing, and cell survival in APP mutant transgenic mice

(2009) Juan Perucho et al.   EXPERIMENTAL NEUROLOGY

Parkin deficiency increases the resistance of midbrain neurons and glia to mild proteasome inhibition: the role of autophagy and glutathione homeostasis

(2009) Maria J. Casarejos et al.   JOURNAL OF NEUROCHEMISTRY

MetaboAnalyst: a web server for metabolomic data analysis and interpretation

(2009) J. Xia et al.   NUCLEIC ACIDS RESEARCH

Physiological pH and Acidic Phospholipids Contribute to Substrate Specificity in Lipidation of Atg8

(2008) Kyoko Oh-oka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

(2008) Derek Narendra et al.   JOURNAL OF CELL BIOLOGY