Membrane-Bound Meet Membraneless in Health and Disease

Therapeutic Dissolution of Aberrant Phases by Nuclear-Import Receptors

(2019) Lin Guo et al.   TRENDS IN CELL BIOLOGY

Stress-induced mRNP granules: Form and function of processing bodies and stress granules

(2019) Anna R. Guzikowski et al.   Wiley Interdisciplinary Reviews-RNA

Coming together to define membrane contact sites

(2019) Luca Scorrano et al.   Nature Communications

Membraneless organelles: P granules in C. elegans

(2019) Elisabeth A. Marnik et al.   TRAFFIC

Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death

(2019) Fatima Gasset-Rosa et al.   NEURON

LC Domain-Mediated Coalescence Is Essential for Otu Enzymatic Activity to Extend Drosophila Lifespan

(2019) Shanming Ji et al.   MOLECULAR CELL

CO 2 ‐fixing liquid droplets: Towards a dissection of the microalgal pyrenoid

(2019) Tobias Wunder et al.   TRAFFIC

COPII‐mediated trafficking at the ER/ERGIC interface

(2019) Jennifer Peotter et al.   TRAFFIC

Germ granules in Drosophila

(2019) Tatjana Trcek et al.   TRAFFIC

Neuronal ribonucleoprotein granules: Dynamic sensors of localized signals

(2019) Nadia Formicola et al.   TRAFFIC

Assembly of COPI and COPII Vesicular Coat Proteins on Membranes

(2018) Julien Béthune et al.   Annual Review of Biophysics

Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites

(2018) Takuya Yoshizawa et al.   CELL

Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation

(2018) Mario Hofweber et al.   CELL

A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins

(2018) Jie Wang et al.   CELL

Stress Granule Assembly Disrupts Nucleocytoplasmic Transport

(2018) Ke Zhang et al.   CELL

Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains

(2018) Lin Guo et al.   CELL

Formation of COPI-coated vesicles at a glance

(2018) Eric C. Arakel et al.   JOURNAL OF CELL SCIENCE

RGG/RG Motif Regions in RNA Binding and Phase Separation

(2018) P. Andrew Chong et al.   JOURNAL OF MOLECULAR BIOLOGY

RNA buffers the phase separation behavior of prion-like RNA binding proteins

(2018) Shovamayee Maharana et al.   SCIENCE

Atomic structures of low-complexity protein segments reveal kinked β sheets that assemble networks

(2018) Michael P. Hughes et al.   SCIENCE

A liquid phase of synapsin and lipid vesicles

(2018) Dragomir Milovanovic et al.   SCIENCE

Context-dependent deposition and regulation of mRNAs in P-bodies

(2018) Congwei Wang et al.   eLife

Pi-Pi contacts are an overlooked protein feature relevant to phase separation

(2018) Robert McCoy Vernon et al.   eLife

The molecular language of membraneless organelles

(2018) Edward Gomes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phase Separation in Biology and Disease

(2018) Julie D. Forman-Kay et al.   JOURNAL OF MOLECULAR BIOLOGY

Poly(ADP-Ribose) Prevents Pathological Phase Separation of TDP-43 by Promoting Liquid Demixing and Stress Granule Localization

(2018) Leeanne McGurk et al.   MOLECULAR CELL

Kinase-controlled phase transition of membraneless organelles in mitosis

(2018) Arpan Kumar Rai et al.   NATURE

GBF1 and Arf1 interact with Miro and regulate mitochondrial positioning within cells

(2018) Laurence Walch et al.   Scientific Reports

The ULK1-FBXW5-SEC23B nexus controls autophagy

(2018) Yeon-Tae Jeong et al.   eLife

Conformational preferences and phase behavior of intrinsically disordered low complexity sequences: insights from multiscale simulations

(2018) Kiersten M Ruff et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

The wisdom of crowds: regulating cell function through condensed states of living matter

(2017) Simon Alberti   JOURNAL OF CELL SCIENCE

P-Body Purification Reveals the Condensation of Repressed mRNA Regulons

(2017) Arnaud Hubstenberger et al.   MOLECULAR CELL

The Dynamics of mRNA Turnover Revealed by Single-Molecule Imaging in Single Cells

(2017) Ivana Horvathova et al.   MOLECULAR CELL

Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics

(2017) Steven Boeynaems et al.   MOLECULAR CELL

Synaptic Vesicle Clusters at Synapses: A Distinct Liquid Phase?

(2017) Dragomir Milovanovic et al.   NEURON

Intersectin associates with synapsin and regulates its nanoscale localization and function

(2017) Fabian Gerth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phospho-Rasputin Stabilization by Sec16 Is Required for Stress Granule Formation upon Amino Acid Starvation

(2017) Angelica Aguilera-Gomez et al.   Cell Reports

Compositional Control of Phase-Separated Cellular Bodies

(2016) Salman F. Banani et al.   CELL

Liquid–liquid phase separation in cellular signaling systems

(2016) P Andrew Chong et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Protein sorting at the ER–Golgi interface

(2016) Natalia Gomez-Navarro et al.   JOURNAL OF CELL BIOLOGY

Altered mRNP granule dynamics in FTLD pathogenesis

(2016) Hilary A. Bowden et al.   JOURNAL OF NEUROCHEMISTRY

Phase separation of signaling molecules promotes T cell receptor signal transduction

(2016) Xiaolei Su et al.   SCIENCE

Principles and Properties of Stress Granules

(2016) David S.W. Protter et al.   TRENDS IN CELL BIOLOGY

In vivo vizualisation of mono-ADP-ribosylation by dPARP16 upon amino-acid starvation

(2016) Angelica Aguilera-Gomez et al.   eLife

SEC16 in COPII coat dynamics at ER exit sites

(2015) Joep Sprangers et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization

(2015) Amandine Molliex et al.   CELL

A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation

(2015) Avinash Patel et al.   CELL

Membrane Trafficking: ER Export Encounters Dualism

(2015) Charles Barlowe   CURRENT BIOLOGY

The C9orf72 repeat expansion disrupts nucleocytoplasmic transport

(2015) Ke Zhang et al.   NATURE

GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport

(2015) Brian D. Freibaum et al.   NATURE

Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS

(2015) Ana Jovičić et al.   NATURE NEUROSCIENCE

TDP-43 Proteinopathy and ALS: Insights into Disease Mechanisms and Therapeutic Targets

(2015) Emma L. Scotter et al.   Neurotherapeutics

The small GTPase Arf1 modulates mitochondrial morphology and function

(2014) K. B. Ackema et al.   EMBO JOURNAL

The polysome-associated proteins Scp160 and Bfr1 prevent P body formation under normal growth conditions

(2014) J. Weidner et al.   JOURNAL OF CELL SCIENCE

Arfs at a Glance

(2014) C. L. Jackson et al.   JOURNAL OF CELL SCIENCE

Biological Significance of the Importin-β Family-Dependent Nucleocytoplasmic Transport Pathways

(2014) Makoto Kimura et al.   TRAFFIC

A stress assembly that confers cell viability by preserving ERES components during amino-acid starvation

(2014) Margarita Zacharogianni et al.   eLife

Filament formation by metabolic enzymes is a specific adaptation to an advanced state of cellular starvation

(2014) Ivana Petrovska et al.   eLife

Dual Specificity Kinase DYRK3 Couples Stress Granule Condensation/Dissolution to mTORC1 Signaling

(2013) Frank Wippich et al.   CELL

COPII — a flexible vesicle formation system

(2013) Elizabeth A Miller et al.   CURRENT OPINION IN CELL BIOLOGY

Stress granules as crucibles of ALS pathogenesis

(2013) Yun R. Li et al.   JOURNAL OF CELL BIOLOGY

Identification of Novel Stress Granule Components That Are Involved in Nuclear Transport

(2013) Hicham Mahboubi et al.   PLoS One

RNA-binding ability of FUS regulates neurodegeneration, cytoplasmic mislocalization and incorporation into stress granules associated with FUS carrying ALS-linked mutations

(2012) J. G. Daigle et al.   HUMAN MOLECULAR GENETICS

Atypical, slowly progressive behavioural variant frontotemporal dementia associated withC9ORF72hexanucleotide expansion

(2012) Baber K Khan et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Phase transitions in the assembly of multivalent signalling proteins

(2012) Pilong Li et al.   NATURE

Drosophila patterning is established by differential association of mRNAs with P bodies

(2012) Timothy T. Weil et al.   NATURE CELL BIOLOGY

PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK- and IRE1α-mediated unfolded protein response

(2012) Miri Jwa et al.   NATURE CELL BIOLOGY

PARP16/ARTD15 Is a Novel Endoplasmic-Reticulum-Associated Mono-ADP-Ribosyltransferase That Interacts with, and Modifies Karyopherin-ß1

(2012) Simone Di Paola et al.   PLoS One

Structural and energetic basis of ALS-causing mutations in the atypical proline–tyrosine nuclear localization signal of the Fused in Sarcoma protein (FUS)

(2012) Zi Chao Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

P-Bodies and Stress Granules: Possible Roles in the Control of Translation and mRNA Degradation

(2012) C. J. Decker et al.   Cold Spring Harbor Perspectives in Biology

Genetic counseling for FTD/ALS caused by the C9ORF72 hexanucleotide expansion

(2012) Jamie C Fong et al.   Alzheimers Research & Therapy

C9ORF72, the new gene on the block, causes C9FTD/ALS: new insights provided by neuropathology

(2011) Eileen H. Bigio   ACTA NEUROPATHOLOGICA

Assembly of RNP granules in stressed and aging oocytes requires nucleoporins and is coordinated with nuclear membrane blebbing

(2011) Joseph R. Patterson et al.   DEVELOPMENTAL BIOLOGY

A yeast functional screen predicts new candidate ALS disease genes

(2011) J. Couthouis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Defects in the Secretory Pathway and High Ca2+ Induce Multiple P-bodies

(2010) Cornelia Kilchert et al.   MOLECULAR BIOLOGY OF THE CELL

The synapsins: Key actors of synapse function and plasticity

(2010) F. Cesca et al.   PROGRESS IN NEUROBIOLOGY

Stress granules

(2009) Paul Anderson et al.   CURRENT BIOLOGY

Unravelling the ultrastructure of stress granules and associated P-bodies in human cells

(2009) S. Souquere et al.   JOURNAL OF CELL SCIENCE

Eukaryotic Stress Granules: The Ins and Outs of Translation

(2009) J. Ross Buchan et al.   MOLECULAR CELL

P bodies promote stress granule assembly inSaccharomyces cerevisiae

(2008) J. Ross Buchan et al.   JOURNAL OF CELL BIOLOGY

Drosophila Sec16 Mediates the Biogenesis of tER Sites Upstream of Sar1 through an Arginine-Rich Motif

(2008) Viorica Ivan et al.   MOLECULAR BIOLOGY OF THE CELL

Stress granules: the Tao of RNA triage

(2008) Paul Anderson et al.   TRENDS IN BIOCHEMICAL SCIENCES