Phase transitions of multivalent proteins can promote clustering of membrane receptors

New Insights into Bacterial Chemoreceptor Array Structure and Assembly from Electron Cryotomography

(2014) Ariane Briegel et al.   BIOCHEMISTRY

Invadopodia in context

(2014) Aviv Bergman et al.   Cell Adhesion & Migration

Symmetric exchange of multi-protein building blocks between stationary focal adhesions and the cytosol

(2014) Jan-Erik Hoffmann et al.   eLife

Eph/ephrin recognition and the role of Eph/ephrin clusters in signaling initiation

(2013) Dimitar B. Nikolov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Higher-Order Assemblies in a New Paradigm of Signal Transduction

(2013) Hao Wu   CELL

Clustered protocadherins

(2013) W. V. Chen et al.   DEVELOPMENT

Cutting Edge: Cell Surface Linker for Activation of T Cells Is Recruited to Microclusters and Is Active in Signaling

(2013) L. Balagopalan et al.   JOURNAL OF IMMUNOLOGY

Structurally encoded intraclass differences in EphA clusters drive distinct cell responses

(2013) Elena Seiradake et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Molecular Mechanisms of SH2- and PTB-Domain-Containing Proteins in Receptor Tyrosine Kinase Signaling

(2013) M. J. Wagner et al.   Cold Spring Harbor Perspectives in Biology

High-Precision Isothermal Titration Calorimetry with Automated Peak-Shape Analysis

(2012) Sandro Keller et al.   ANALYTICAL CHEMISTRY

Active Remodeling of Cortical Actin Regulates Spatiotemporal Organization of Cell Surface Molecules

(2012) Kripa Gowrishankar et al.   CELL

Myoblast fusion: lessons from flies and mice

(2012) S. M. Abmayr et al.   DEVELOPMENT

WIP Remodeling Actin behind the Scenes: How WIP Reshapes Immune and Other Functions

(2012) Elad Noy et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Direct Regulation of Nephrin Tyrosine Phosphorylation by Nck Adaptor Proteins

(2012) Laura A. New et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stoichiometry of Nck-dependent actin polymerization in living cells

(2012) Jonathon A. Ditlev et al.   JOURNAL OF CELL BIOLOGY

Dock mediates Scar- and WASp-dependent actin polymerization through interaction with cell adhesion molecules in founder cells and fusion-competent myoblasts

(2012) Balasankara Reddy Kaipa et al.   JOURNAL OF CELL SCIENCE

Multiple repeat elements within the FAM21 tail link the WASH actin regulatory complex to the retromer

(2012) Da Jia et al.   MOLECULAR BIOLOGY OF THE CELL

Phase transitions in the assembly of multivalent signalling proteins

(2012) Pilong Li et al.   NATURE

Disentangling nestedness from models of ecological complexity

(2012) Alex James et al.   NATURE

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Bacterial chemoreceptor arrays are hexagonally packed trimers of receptor dimers networked by rings of kinase and coupling proteins

(2012) A. Briegel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Signaling from the Living Plasma Membrane

(2011) Hernán E. Grecco et al.   CELL

Transforming binding affinities from three dimensions to two with application to cadherin clustering

(2011) Yinghao Wu et al.   NATURE

Physical Mechanisms of Signal Integration by WASP Family Proteins

(2010) Shae B. Padrick et al.   Annual Review of Biochemistry

Specific tyrosine phosphorylation sites on cortactin regulate Nck1-dependent actin polymerization in invadopodia

(2010) M. Oser et al.   JOURNAL OF CELL SCIENCE

Chemotaxis kinase CheA is activated by three neighbouring chemoreceptor dimers as effectively as by receptor clusters

(2010) Mingshan Li et al.   MOLECULAR MICROBIOLOGY

The Fas–FADD death domain complex structure reveals the basis of DISC assembly and disease mutations

(2010) Liwei Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

WASH and WAVE actin regulators of the Wiskott-Aldrich syndrome protein (WASP) family are controlled by analogous structurally related complexes

(2010) D. Jia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipid Rafts As a Membrane-Organizing Principle

(2010) D. Lingwood et al.   SCIENCE

Restriction of Receptor Movement Alters Cellular Response: Physical Force Sensing by EphA2

(2010) K. Salaita et al.   SCIENCE

Understanding the Structure and Function of the Immunological Synapse

(2010) M. L. Dustin et al.   Cold Spring Harbor Perspectives in Biology

Nck adapter proteins: functional versatility in T cells

(2009) Marcus Lettau et al.   Cell Communication and Signaling

The Arp2/3 Activator WASH Controls the Fission of Endosomes through a Large Multiprotein Complex

(2009) Emmanuel Derivery et al.   DEVELOPMENTAL CELL

A FAM21-Containing WASH Complex Regulates Retromer-Dependent Sorting

(2009) Timothy S. Gomez et al.   DEVELOPMENTAL CELL

Nephrin—signature molecule of the glomerular podocyte?

(2009) Gavin I Welsh et al.   JOURNAL OF PATHOLOGY

Nck Proteins Maintain the Adult Glomerular Filtration Barrier

(2009) N. Jones et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The Fas–FADD death domain complex structure unravels signalling by receptor clustering

(2009) Fiona L. Scott et al.   NATURE

Self-Organization of the Escherichia coli Chemotaxis Network Imaged with Super-Resolution Light Microscopy

(2009) Derek Greenfield et al.   PLOS BIOLOGY

Quantitative Fluorescence Microscopy Using Supported Lipid Bilayer Standards

(2008) William J. Galush et al.   BIOPHYSICAL JOURNAL

Nanoclusters of GPI-Anchored Proteins Are Formed by Cortical Actin-Driven Activity

(2008) Debanjan Goswami et al.   CELL

Predominance of activated EGFR higher-order oligomers on the cell surface

(2008) Andrew H. A. Clayton et al.   GROWTH FACTORS

A crucial role in cell spreading for the interaction of Abl PxxP motifs with Crk and Nck adaptors

(2008) S. Antoku et al.   JOURNAL OF CELL SCIENCE

Phosphorylated YDXV Motifs and Nck SH2/SH3 Adaptors Act Cooperatively To Induce Actin Reorganization

(2008) I. M. Blasutig et al.   MOLECULAR AND CELLULAR BIOLOGY

A quantitative study of the recruitment potential of all intracellular tyrosine residues on EGFR, FGFR1 and IGF1R

(2008) Alexis Kaushansky et al.   Molecular BioSystems

Hierarchical Regulation of WASP/WAVE Proteins

(2008) Shae B. Padrick et al.   MOLECULAR CELL