The DEAD-box helicase eIF4A

Specific Domains in Yeast Translation Initiation Factor eIF4G Strongly Bias RNA Unwinding Activity of the eIF4F Complex toward Duplexes with 5′-Overhangs

(2012) Vaishnavi Rajagopal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The eukaryotic initiation factor eIF4H facilitates loop-binding, repetitive RNA unwinding by the eIF4A DEAD-box helicase

(2012) Yingjie Sun et al.   NUCLEIC ACIDS RESEARCH

RNA helicases in infection and disease

(2012) Lenz Steimer et al.   RNA Biology

A cellular response linking eIF4AI activity to eIF4AII transcription

(2012) G. Galicia-Vazquez et al.   RNA

Human eIF4AIII interacts with an eIF4G-like partner, NOM1, revealing an evolutionarily conserved function outside the exon junction complex

(2011) A. Alexandrov et al.   GENES & DEVELOPMENT

Duplex Unwinding and ATPase Activities of the DEAD-Box Helicase eIF4A Are Coupled by eIF4G and eIF4B

(2011) Ali R. ze et al.   JOURNAL OF MOLECULAR BIOLOGY

Analyses of the Functional Regions of DEAD-Box RNA “Helicases” with Deletion and Chimera Constructs Tested In Vivo and In Vitro

(2011) Josette Banroques et al.   JOURNAL OF MOLECULAR BIOLOGY

A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP6 in mRNA export

(2011) Ben Montpetit et al.   NATURE

mRNA helicases: the tacticians of translational control

(2011) Armen Parsyan et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

From unwinding to clamping — the DEAD box RNA helicase family

(2011) Patrick Linder et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Identification of a signature motif for the eIF4a3–SECIS interaction

(2011) Michael E. Budiman et al.   NUCLEIC ACIDS RESEARCH

Solution structures of DEAD-box RNA chaperones reveal conformational changes and nucleic acid tethering by a basic tail

(2011) A. L. Mallam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple elements in the eIF4G1 N-terminus promote assembly of eIF4G1•PABP mRNPsin vivo

(2010) Eun-Hee Park et al.   EMBO JOURNAL

The mechanism of eukaryotic translation initiation and principles of its regulation

(2010) Richard J. Jackson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Synergistic activation of eIF4A by eIF4B and eIF4G

(2010) Klaus H. Nielsen et al.   NUCLEIC ACIDS RESEARCH

eIF4G stimulates the activity of the DEAD box protein eIF4A by a conformational guidance mechanism

(2010) Manuel Hilbert et al.   NUCLEIC ACIDS RESEARCH

Insights into the recruitment of the NMD machinery from the crystal structure of a core EJC-UPF3b complex.

(2010) G. Buchwald et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The DEAD Box Helicase YxiN Maintains a Closed Conformation during ATP Hydrolysis

(2009) Regula Aregger et al.   BIOCHEMISTRY

How Does a Scanning Ribosomal Particle Move along the 5′-Untranslated Region of Eukaryotic mRNA? Brownian Ratchet Model

(2009) Alexander S. Spirin   BIOCHEMISTRY

The mechanism of ATP-dependent RNA unwinding by DEAD box proteins

(2009) Manuel Hilbert et al.   BIOLOGICAL CHEMISTRY

Topology and Regulation of the Human eIF4A/4G/4H Helicase Complex in Translation Initiation

(2009) Assen Marintchev et al.   CELL

Inhibitors of translation initiation as cancer therapeutics

(2009) Lisa Lindqvist et al.   Future Medicinal Chemistry

The DEXD/H-box RNA Helicase DDX19 Is Regulated by an α-Helical Switch

(2009) Ruairi Collins et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intrinsic RNA Binding by the Eukaryotic Initiation Factor 4F Depends on a Minimal RNA Length but Not on the m7G Cap

(2009) Nicholas M. Kaye et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Solution and Crystal Structures of mRNA Exporter Dbp5p and Its Interaction with Nucleotides

(2009) Jing-Song Fan et al.   JOURNAL OF MOLECULAR BIOLOGY

Eukaryotic Initiation Factor 4a3 Is a Selenium-Regulated RNA-Binding Protein that Selectively Inhibits Selenocysteine Incorporation

(2009) Michael E. Budiman et al.   MOLECULAR CELL

Structure of the Yeast DEAD Box Protein Mss116p Reveals Two Wedges that Crimp RNA

(2009) Mark Del Campo et al.   MOLECULAR CELL

The mRNA export protein DBP5 binds RNA and the cytoplasmic nucleoporin NUP214 in a mutually exclusive manner

(2009) Holger von Moeller et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A conformational change in the helicase core is necessary but not sufficient for RNA unwinding by the DEAD box helicase YxiN

(2009) Anne R. Karow et al.   NUCLEIC ACIDS RESEARCH

Crystal structure of the eIF4A-PDCD4 complex

(2009) J. H. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural and functional analysis of the interaction between the nucleoporin Nup214 and the DEAD-box helicase Ddx19

(2009) J. Napetschnig et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Translocation and Unwinding Mechanisms of RNA and DNA Helicases

(2008) Anna Marie Pyle   Annual Review of Biophysics

The ATPase Cycle Mechanism of the DEAD-box rRNA Helicase, DbpA

(2008) Arnon Henn et al.   JOURNAL OF MOLECULAR BIOLOGY

Translational Control by a Small RNA: Dendritic BC1 RNA Targets the Eukaryotic Initiation Factor 4A Helicase Mechanism

(2008) D. Lin et al.   MOLECULAR AND CELLULAR BIOLOGY

The putative RNase P motif in the DEAD box helicase Hera is dispensable for efficient interaction with RNA and helicase activity

(2008) Martin H. Linden et al.   NUCLEIC ACIDS RESEARCH

A novel dimerization motif in the C-terminal domain of the Thermus thermophilus DEAD box helicase Hera confers substantial flexibility †

(2008) Dagmar Klostermeier et al.   NUCLEIC ACIDS RESEARCH

DEAD-box proteins can completely separate an RNA duplex using a single ATP

(2008) Y. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cooperative binding of ATP and RNA induces a closed conformation in a DEAD box RNA helicase

(2008) B. Theissen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATP hydrolysis is required for DEAD-box protein recycling but not for duplex unwinding

(2008) F. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structure of the yeast eIF4A-eIF4G complex: An RNA-helicase controlled by protein-protein interactions

(2008) P. Schutz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism of ATP turnover inhibition in the EJC

(2008) K. H. Nielsen et al.   RNA

Interactions between eIF4AI and its accessory factors eIF4B and eIF4H

(2008) N. Rozovsky et al.   RNA

Cap-dependent eukaryotic initiation factor-mRNA interactions probed by cross-linking

(2008) L. Lindqvist et al.   RNA

The Bacillus subtilis RNA Helicase YxiN is Distended in Solution

(2007) Shuying Wang et al.   BIOPHYSICAL JOURNAL

Function of the C-terminal Domain of the DEAD-box Protein Mss116p Analyzed in Vivo and in Vitro

(2007) Georg Mohr et al.   JOURNAL OF MOLECULAR BIOLOGY