The emerging role of RNA modifications in the regulation of mRNA stability

Characterization of METTL16 as a cytoplasmic RNA binding protein

(2020) Daniel J. Nance et al.   PLoS One

Molecular Mechanisms Driving mRNA Degradation by m6A Modification

(2020) Yujin Lee et al.   TRENDS IN GENETICS

UPFront and center in RNA decay: UPF1 in nonsense-mediated mRNA decay and beyond

(2019) Yoon Ki Kim et al.   RNA

Recent Progress on the Molecular Mechanism of Quality Controls Induced by Ribosome Stalling

(2019) Ken Ikeuchi et al.   Frontiers in Genetics

RNA 2’-O-Methylation (Nm) Modification in Human Diseases

(2019) Dilyana G. Dimitrova et al.   Genes

Endoribonucleolytic Cleavage of m6A-Containing RNAs by RNase P/MRP Complex

(2019) Ok Hyun Park et al.   MOLECULAR CELL

Targeting the RNA m6A Reader YTHDF2 Selectively Compromises Cancer Stem Cells in Acute Myeloid Leukemia

(2019) Jasmin Paris et al.   Cell Stem Cell

Transcriptome-wide Mapping of Internal N7-Methylguanosine Methylome in Mammalian mRNA

(2019) Li-Sheng Zhang et al.   MOLECULAR CELL

Where, When, and How: Context-Dependent Functions of RNA Methylation Writers, Readers, and Erasers

(2019) Hailing Shi et al.   MOLECULAR CELL

RNA modifications regulating cell fate in cancer

(2019) Sylvain Delaunay et al.   NATURE CELL BIOLOGY

Quality and quantity control of gene expression by nonsense-mediated mRNA decay

(2019) Tatsuaki Kurosaki et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Identification of the m6Am Methyltransferase PCIF1 Reveals the Location and Functions of m6Am in the Transcriptome

(2019) Konstantinos Boulias et al.   MOLECULAR CELL

PCIF1 Catalyzes m6Am mRNA Methylation to Regulate Gene Expression

(2019) Erdem Sendinc et al.   MOLECULAR CELL

5-methylcytosine promotes pathogenesis of bladder cancer through stabilizing mRNAs

(2019) Xin Chen et al.   NATURE CELL BIOLOGY

Modification of messenger RNA by 2′-O-methylation regulates gene expression in vivo

(2019) Brittany A. Elliott et al.   Nature Communications

Dynamic methylome of internal mRNA N7-methylguanosine and its regulatory role in translation

(2019) Lionel Malbec et al.   CELL RESEARCH

RNA 5-Methylcytosine Facilitates the Maternal-to-Zygotic Transition by Preventing Maternal mRNA Decay

(2019) Ying Yang et al.   MOLECULAR CELL

How do cells cope with RNA damage and its consequences?

(2019) Liewei L. Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cellular RNA surveillance in health and disease

(2019) Sandra L. Wolin et al.   SCIENCE

The Biogenesis and Precise Control of RNA m6A Methylation

(2019) Huilin Huang et al.   TRENDS IN GENETICS

N6-methyladenosine-binding proteins suppress HIV-1 infectivity and viral production

(2018) Wuxun Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation

(2018) Huilin Huang et al.   NATURE CELL BIOLOGY

Specific binding of PCBP1 to heavily oxidized RNA to induce cell death

(2018) Takashi Ishii et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The m6A reader protein YTHDC2 interacts with the small ribosomal subunit and the 5′-3′ exoribonuclease XRN1

(2018) Jens Kretschmer et al.   RNA

Chemical Modifications in the Life of an mRNA Transcript

(2018) Sigrid Nachtergaele et al.   Annual Review of Genetics

Methylation of Structured RNA by the m6A Writer METTL16 Is Essential for Mouse Embryonic Development

(2018) Mateusz Mendel et al.   MOLECULAR CELL

Differential m6A, m6Am, and m1A Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm

(2018) Jiangbo Wei et al.   MOLECULAR CELL

Epitranscriptomic Code and Its Alterations in Human Disease

(2018) Rajashekar Varma Kadumuri et al.   TRENDS IN MOLECULAR MEDICINE

Post-transcriptional pseudouridylation in mRNA as well as in some major types of noncoding RNAs

(2018) Hironori Adachi et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Acetylation of Cytidine in mRNA Promotes Translation Efficiency

(2018) Daniel Arango et al.   CELL

A novel m6A reader Prrc2a controls oligodendroglial specification and myelination

(2018) Rong Wu et al.   CELL RESEARCH

Cap-specific, terminal N6-methylation by a mammalian m6Am methyltransferase

(2018) Hanxiao Sun et al.   CELL RESEARCH

Structural and molecular mechanisms for the control of eukaryotic 5′–3′ mRNA decay

(2018) Jeffrey S. Mugridge et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cap-specific terminal N6-methylation of RNA by an RNA polymerase II–associated methyltransferase

(2018) Shinichiro Akichika et al.   SCIENCE

m6A-dependent maternal mRNA clearance facilitates zebrafish maternal-to-zygotic transition

(2017) Boxuan Simen Zhao et al.   NATURE

Epitranscriptome sequencing technologies: decoding RNA modifications

(2017) Xiaoyu Li et al.   NATURE METHODS

Detecting RNA modifications in the epitranscriptome: predict and validate

(2017) Mark Helm et al.   NATURE REVIEWS GENETICS

N6-methyladenosine (m6A) recruits and repels proteins to regulate mRNA homeostasis

(2017) Raghu R Edupuganti et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The non-stop decay mRNA surveillance pathway is required for oxidative stress tolerance

(2017) Nur H. Jamar et al.   NUCLEIC ACIDS RESEARCH

MODOMICS: a database of RNA modification pathways. 2017 update

(2017) Pietro Boccaletto et al.   NUCLEIC ACIDS RESEARCH

Essential role of METTL3-mediated m6A modification in glioma stem-like cells maintenance and radioresistance

(2017) A Visvanathan et al.   ONCOGENE

mRNA pseudouridylation affects RNA metabolism in the parasite Toxoplasma gondii

(2017) Margaret A. Nakamoto et al.   RNA

The RNA modification landscape in human disease

(2017) Nicky Jonkhout et al.   RNA

Roles of RNase P and Its Subunits

(2017) Nayef Jarrous   TRENDS IN GENETICS

N6-methyladenosine (m6A) recruits and repels proteins to regulate mRNA homeostasis

(2017) Raghu R Edupuganti et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

RNA Pseudouridylation in Physiology and Medicine: For Better and for Worse

(2017) et al.   Genes

Beyond the known functions of the CCR4-NOT complex in gene expression regulatory mechanisms

(2016) Marta Ukleja et al.   BIOESSAYS

Identification and molecular characterization of cellular factors required for glucocorticoid receptor-mediated mRNA decay

(2016) Ok Hyun Park et al.   GENES & DEVELOPMENT

Reversible methylation of m6Am in the 5′ cap controls mRNA stability

(2016) Jan Mauer et al.   NATURE

Ribosome-based quality control of mRNA and nascent peptides

(2016) Carrie L. Simms et al.   Wiley Interdisciplinary Reviews-RNA

The Ccr4-Not complex is a key regulator of eukaryotic gene expression

(2016) Martine A. Collart   Wiley Interdisciplinary Reviews-RNA

N6-methyladenosine of HIV-1 RNA regulates viral infection and HIV-1 Gag protein expression

(2016) Nagaraja Tirumuru et al.   eLife

The Clothes Make the mRNA: Past and Present Trends in mRNP Fashion

(2015) Guramrit Singh et al.   Annual Review of Biochemistry

A new function of glucocorticoid receptor: regulation of mRNA stability

(2015) Ok Hyun Park et al.   BMB Reports

Role of Auf1 in elimination of oxidatively damaged messenger RNA in human cells

(2015) Takashi Ishii et al.   FREE RADICAL BIOLOGY AND MEDICINE

Chemical pulldown reveals dynamic pseudouridylation of the mammalian transcriptome

(2015) Xiaoyu Li et al.   Nature Chemical Biology

Glucocorticoid receptor interacts with PNRC2 in a ligand-dependent manner to recruit UPF1 for rapid mRNA degradation

(2015) Hana Cho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptome-wide Mapping Reveals Widespread Dynamic-Regulated Pseudouridylation of ncRNA and mRNA

(2014) Schraga Schwartz et al.   CELL

Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase

(2014) Xiao-Li Ping et al.   CELL RESEARCH

Pseudouridine profiling reveals regulated mRNA pseudouridylation in yeast and human cells

(2014) Thomas M. Carlile et al.   NATURE

N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cells

(2014) Yang Wang et al.   NATURE CELL BIOLOGY

An Active Role for the Ribosome in Determining the Fate of Oxidized mRNA

(2014) Carrie L. Simms et al.   Cell Reports

Perturbation of m6A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5′ Sites

(2014) Schraga Schwartz et al.   Cell Reports

N6-methyladenosine-dependent regulation of messenger RNA stability

(2013) Xiao Wang et al.   NATURE

Identification of direct targets and modified bases of RNA cytosine methyltransferases

(2013) Vahid Khoddami et al.   NATURE BIOTECHNOLOGY

A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation

(2013) Jianzhao Liu et al.   Nature Chemical Biology

DNA Base Damage by Reactive Oxygen Species, Oxidizing Agents, and UV Radiation

(2013) J. Cadet et al.   Cold Spring Harbor Perspectives in Biology

NSun2-Mediated Cytosine-5 Methylation of Vault Noncoding RNA Determines Its Processing into Regulatory Small RNAs

(2013) Shobbir Hussain et al.   Cell Reports

Characterizing 5-methylcytosine in the mammalian epitranscriptome

(2013) Shobbir Hussain et al.   GENOME BIOLOGY

Global analysis of RNA oxidation in Saccharomyces cerevisiae

(2012) Anastasia McKinlay et al.   BIOTECHNIQUES

Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels

(2012) Masato Kato et al.   CELL

Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons

(2012) Kate D. Meyer et al.   CELL

RNA modifications by oxidation: A novel disease mechanism?

(2012) Henrik E. Poulsen et al.   FREE RADICAL BIOLOGY AND MEDICINE

ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility

(2012) Guanqun Zheng et al.   MOLECULAR CELL

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

(2012) Dan Dominissini et al.   NATURE

Surveillance pathways rescuing eukaryotic ribosomes lost in translation

(2012) Marc Graille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Widespread occurrence of 5-methylcytosine in human coding and non-coding RNA

(2012) Jeffrey E. Squires et al.   NUCLEIC ACIDS RESEARCH

Converting nonsense codons into sense codons by targeted pseudouridylation

(2011) John Karijolich et al.   NATURE

N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

(2011) Guifang Jia et al.   Nature Chemical Biology

Viperin mRNA is a novel target for the human RNase MRP/RNase P endoribonuclease

(2010) Sandy Mattijssen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Archaeal/Eukaryal RNase P: subunits, functions and RNA diversification

(2010) Nayef Jarrous et al.   NUCLEIC ACIDS RESEARCH

5-methylcytosine in RNA: detection, enzymatic formation and biological functions

(2009) Yuri Motorin et al.   NUCLEIC ACIDS RESEARCH

A role for Q/N-rich aggregation-prone regions in P-body localization

(2008) M. A. M. Reijns et al.   JOURNAL OF CELL SCIENCE

Incorporation of Pseudouridine Into mRNA Yields Superior Nonimmunogenic Vector With Increased Translational Capacity and Biological Stability

(2008) Katalin Karikó et al.   MOLECULAR THERAPY

PID: the Pathway Interaction Database

(2008) Carl F. Schaefer et al.   NUCLEIC ACIDS RESEARCH