Seaweed Phenolics: From Extraction to Applications

Absolute Configuration of Mycosporine-Like Amino Acids, Their Wound Healing Properties and In Vitro Anti-Aging Effects

(2020) Maria Orfanoudaki et al.   Marine Drugs

Putative Inhibitors of SARS-CoV-2 Main Protease from A Library of Marine Natural Products: A Virtual Screening and Molecular Modeling Study

(2020) Davide Gentile et al.   Marine Drugs

Conservation and diversification of flavonoid metabolism in the plant kingdom

(2020) Weiwei Wen et al.   CURRENT OPINION IN PLANT BIOLOGY

Column Characterization and Selection Systems in Reversed-Phase High-Performance Liquid Chromatography

(2019) Petar Žuvela et al.   CHEMICAL REVIEWS

A Standardized Phlorotannin Supplement Attenuates Caffeine-Induced Sleep Disruption in Mice

(2019) Sangoh Kwon et al.   Nutrients

Isolation and Potential Biological Applications of Haloaryl Secondary Metabolites from Macroalgae

(2019) Ana Jesus et al.   Marine Drugs

Anti-Diabetic Activity of 2,3,6-Tribromo-4,5-Dihydroxybenzyl Derivatives from Symphyocladia latiuscula through PTP1B Downregulation and α-Glucosidase Inhibition

(2019) Pradeep Paudel et al.   Marine Drugs

Optimization of Phlorotannins Extraction from Fucus vesiculosus and Evaluation of Their Potential to Prevent Metabolic Disorders

(2019) Marcelo Catarino et al.   Marine Drugs

Dual BACE1 and Cholinesterase Inhibitory Effects of Phlorotannins from Ecklonia cava—An In Vitro and in Silico Study

(2019) Jinhyuk Lee et al.   Marine Drugs

Antibacterial Oligomeric Polyphenols from the Green Alga Cladophora socialis

(2019) Serge Lavoie et al.   JOURNAL OF ORGANIC CHEMISTRY

Identification of Polyphenols from Chilean Brown Seaweeds Extracts by LC-DAD-ESI-MS/MS

(2019) Carla Olate-Gallegos et al.   Journal of Aquatic Food Product Technology

Characterization of functional materials derived from tropical red seaweed Hypnea musciformis produced by subcritical water extraction systems

(2019) Ratih Pangestuti et al.   JOURNAL OF APPLIED PHYCOLOGY

Seaweeds to the rescue of forgotten diseases: a review

(2019) Yolanda Freile-Pelegrín et al.   BOTANICA MARINA

Dieckol inhibits non‐small–cell lung cancer cell proliferation and migration by regulating the PI3K/AKT signaling pathway

(2019) Chun‐Hong Wang et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Probing Multi-Target Action of Phlorotannins as New Monoamine Oxidase Inhibitors and Dopaminergic Receptor Modulators with the Potential for Treatment of Neuronal Disorders

(2019) Su Hui Seong et al.   Marine Drugs

Phenolic Content of Brown Algae (Pheophyceae) Species: Extraction, Identification, and Quantification

(2019) Ivana Generalić Mekinić et al.   Biomolecules

Marine Algae Metabolites as Promising Therapeutics for the Prevention and Treatment of HIV/AIDS

(2019) Natalya N. Besednova et al.   Metabolites

Biomarkers of seaweed intake

(2019) Muyao Xi et al.   Genes and Nutrition

Enhancing antioxidant and antimutagenic activity of the green seaweed Rhizoclonium riparium by bioassay-guided solvent partitioning

(2019) I. Osuna-Ruíz et al.   JOURNAL OF APPLIED PHYCOLOGY

Dieckol or phlorofucofuroeckol extracted from Ecklonia cava suppresses lipopolysaccharide-mediated human breast cancer cell migration and invasion

(2019) Young-Ju Lee et al.   JOURNAL OF APPLIED PHYCOLOGY

Phlorofucofuroeckol A from Edible Brown Alga Ecklonia Cava Enhances Osteoblastogenesis in Bone Marrow-Derived Human Mesenchymal Stem Cells

(2019) Jung Hwan Oh et al.   Marine Drugs

The Protective Effect of Mycosporine-Like Amino Acids (MAAs) from Porphyra yezoensis in a Mouse Model of UV Irradiation-Induced Photoaging

(2019) Rui Ying et al.   Marine Drugs

New insecticides and antimicrobials derived from Sargassum wightii and Halimeda gracillis seaweeds: Toxicity against mosquito vectors and antibiofilm activity against microbial pathogens

(2019) S. Suganya et al.   SOUTH AFRICAN JOURNAL OF BOTANY

Eckol inhibits Reg3A‑induced proliferation of human SW1990 pancreatic cancer cells

(2019) Mengya Zhang et al.   Experimental and Therapeutic Medicine

The Origin and Evolution of Plant Flavonoid Metabolism

(2019) Keiko Yonekura-Sakakibara et al.   Frontiers in Plant Science

Polyphenol-Rich Extracts from Brown Macroalgae Lessonia trabeculate Attenuate Hyperglycemia and Modulate Gut Microbiota in High-Fat Diet and Streptozotocin-Induced Diabetic Rats

(2019) Yuan Yuan et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Phenolic, flavonoid, and amino acid compositions reveal that selected tropical seaweeds have the potential to be functional food ingredients

(2019) Bhakti Tanna et al.   JOURNAL OF FOOD PROCESSING AND PRESERVATION

Advanced sensing technologies of phenolic compounds for pharmaceutical and biomedical analysis

(2019) Liya Ge et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Phlorotannins from Ecklonia cava Attenuates Palmitate-Induced Endoplasmic Reticulum Stress and Leptin Resistance in Hypothalamic Neurons

(2019) Seyeon Oh et al.   Marine Drugs

Beneficial Effects of Dietary Polyphenols on Gut Microbiota and Strategies to Improve Delivery Efficiency

(2019) Amit Kumar Singh et al.   Nutrients

The Potential of Seaweeds as a Source of Functional Ingredients of Prebiotic and Antioxidant Value

(2019) Andrea Gomez-Zavaglia et al.   Antioxidants

Diverse Applications of Marine Macroalgae

(2019) Adriana Leandro et al.   Marine Drugs

Antioxidant, Anticancer Activity and Phytochemical Analysis of Green Algae, Chaetomorpha Collected from the Arabian Gulf

(2019) Samina Hyder Haq et al.   Scientific Reports

The Quest for Phenolic Compounds from Macroalgae: A Review of Extraction and Identification Methodologies

(2019) Sónia A. O. Santos et al.   Biomolecules

Quantification of Polyphenols in Seaweeds: A Case Study of Ulva intestinalis

(2019) Marie Emilie Wekre et al.   Antioxidants

Eckmaxol, a Phlorotannin Extracted from Ecklonia maxima, Produces Anti-β-amyloid Oligomer Neuroprotective Effects Possibly via Directly Acting on Glycogen Synthase Kinase 3β

(2018) Jialing Wang et al.   ACS Chemical Neuroscience

Microwave assisted extraction of phenolic compounds from four economic brown macroalgae species and evaluation of their antioxidant activities and inhibitory effects on α-amylase, α-glucosidase, pancreatic lipase and tyrosinase

(2018) Yuan Yuan et al.   FOOD RESEARCH INTERNATIONAL

Evaluation of bioactivity of phenolic compounds from the brown seaweed of Sargassum fusiforme and development of their stable emulsion

(2018) N. Liu et al.   JOURNAL OF APPLIED PHYCOLOGY

Temporal and spatial variability of mycosporine-like amino acids and pigments in three edible red seaweeds from western Ireland

(2018) Freddy Guihéneuf et al.   JOURNAL OF APPLIED PHYCOLOGY

Phlorotannin-rich fraction from Ishige foliacea brown seaweed prevents the scopolamine-induced memory impairment via regulation of ERK-CREB-BDNF pathway

(2018) Min Young Um et al.   Journal of Functional Foods

The Impact of a Single Dose of a Polyphenol-Rich Seaweed Extract on Postprandial Glycaemic Control in Healthy Adults: A Randomised Cross-Over Trial

(2018) Margaret Murray et al.   Nutrients

Comparative analysis of in vitro antioxidant capacities of mycosporine-like amino acids (MAAs)

(2018) Priscila Torres et al.   Algal Research-Biomass Biofuels and Bioproducts

Profiling phlorotannins from Fucus spp. of the Northern Portuguese coastline: Chemical approach by HPLC-DAD-ESI/MS n and UPLC-ESI-QTOF/MS

(2018) Graciliana Lopes et al.   Algal Research-Biomass Biofuels and Bioproducts

Experimental processing of seaweeds for biofuels

(2018) Izabela Michalak   Wiley Interdisciplinary Reviews-Energy and Environment

Potential Role of Seaweed Polyphenols in Cardiovascular-Associated Disorders

(2018) Manuel Gómez-Guzmán et al.   Marine Drugs

Phlorotannins are Polyphenolic Metabolites of Brown Algae

(2018) T. I. Imbs et al.   Russian Journal of Marine Biology

Role of Green Macroalgae Enteromorpha Prolifera Polyphenols in the Modulation of Gene Expression and Intestinal Microflora Profiles in Type 2 Diabetic Mice

(2018) Guopeng Lin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Antidiabetic Potential of Green Seaweed Enteromorpha prolifera Flavonoids Regulating Insulin Signaling Pathway and Gut Microbiota in Type 2 Diabetic Mice

(2018) Xin Yan et al.   JOURNAL OF FOOD SCIENCE

Anti-Neuroinflammatory Property of Phlorotannins from Ecklonia cava on Aβ25-35-Induced Damage in PC12 Cells

(2018) Seungeun Lee et al.   Marine Drugs

Phytochemical and Analytical Characterization of Novel Sulfated Coumarins in the Marine Green Macroalga Dasycladus vermicularis (Scopoli) Krasser

(2018) Anja Hartmann et al.   MOLECULES

Bromophenol (5-bromo-3,4-dihydroxybenzaldehyde) isolated from red alga Polysiphonia morrowii inhibits adipogenesis by regulating expression of adipogenic transcription factors and AMP-activated protein kinase activation in 3T3-L1 adipocytes

(2018) Seok-Chun Ko et al.   PHYTOTHERAPY RESEARCH

Metabolite profiling, antioxidant, scavenging and anti-proliferative activities of selected tropical green seaweeds reveal the nutraceutical potential of Caulerpa spp.

(2018) Bhakti Tanna et al.   Algal Research-Biomass Biofuels and Bioproducts

A comprehensive review of traditional uses, bioactivity potential, and chemical diversity of the genus Gracilaria (Gracilariales, Rhodophyta)

(2018) Priscila Torres et al.   Algal Research-Biomass Biofuels and Bioproducts

Phenolic compounds from three brown seaweed species using LC-DAD–ESI-MS/MS

(2017) Rubén Agregán et al.   FOOD RESEARCH INTERNATIONAL

Assessment of the Nutritive, Biochemical, Antioxidant and Antibacterial Potential of Eight Tropical Macro algae Along Kachchh Coast, India as Human Food Supplements

(2017) Dhara C. Dixit et al.   Journal of Aquatic Food Product Technology

Fabrication and characterization of phlorotannins/poly (vinyl alcohol) hydrogel for wound healing application

(2017) Hyeon-Ho Park et al.   JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION

Cardioprotective Effects of a Phlorotannin Extract Against Doxorubicin-Induced Cardiotoxicity in a Rat Model

(2017) Hyo-Suk Ahn et al.   JOURNAL OF MEDICINAL FOOD

Antioxidant capacity of Colombian seaweeds: 1. Extracts obtained from Gracilaria mammillaris by means of supercritical fluid extraction

(2017) Mónica Ospina et al.   JOURNAL OF SUPERCRITICAL FLUIDS

α-Glucosidase and Protein Tyrosine Phosphatase 1B Inhibitory Activity of Plastoquinones from Marine Brown Alga Sargassum serratifolium

(2017) Md. Ali et al.   Marine Drugs

Effect of simulated gastrointestinal digestion and fermentation on polyphenolic content and bioactivity of brown seaweed phlorotannin-rich extracts

(2017) Giulia Corona et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Highly oxygenated antioxidative 2H-chromen derivative from the red seaweed Gracilaria opuntia with pro-inflammatory cyclooxygenase and lipoxygenase inhibitory properties

(2017) Fasina Makkar et al.   NATURAL PRODUCT RESEARCH

A polycaprolactone/fish collagen/alginate biocomposite supplemented with phlorotannin for hard tissue regeneration

(2017) JeongHyeong Im et al.   RSC Advances

Mycosporine-Like Amino Acids for Skin Photoprotection

(2017) Karl P. Lawrence et al.   CURRENT MEDICINAL CHEMISTRY

Seaweeds for livestock diets: A review

(2016) Harinder P.S. Makkar et al.   ANIMAL FEED SCIENCE AND TECHNOLOGY

Flavonoid compounds from the red marine alga Alsidium corallinum protect against potassium bromate-induced nephrotoxicity in adult mice

(2016) Hajer Ben Saad et al.   ENVIRONMENTAL TOXICOLOGY

Inhibition of algal bromophenols and their related phenols against glucose 6-phosphate dehydrogenase

(2016) Daisuke Mikami et al.   FITOTERAPIA

Octaphlorethol A, a marine algae product, exhibits antidiabetic effects in type 2 diabetic mice by activating AMP-activated protein kinase and upregulating the expression of glucose transporter 4

(2016) Seung-Hong Lee et al.   FOOD AND CHEMICAL TOXICOLOGY

Protective effects of the seaweed phlorotannin polyphenolic compound dieckol on gentamicin-induced damage in auditory hair cells

(2016) Mun Young Chang et al.   INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY

MicroRNA134 Mediated Upregulation of JNK and Downregulation of NFkB Signalings Are Critically Involved in Dieckol Induced Antihepatic Fibrosis

(2016) Sang Yoon Lee et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Structural characterization and comparative biomedical properties of phloroglucinol from Indian brown seaweeds

(2016) Ramachandran Karthik et al.   JOURNAL OF APPLIED PHYCOLOGY

Algae as nutritional and functional food sources: revisiting our understanding

(2016) Mark L. Wells et al.   JOURNAL OF APPLIED PHYCOLOGY

Nutritional quality of some wild and cultivated seaweeds: Nutrient composition, total phenolic content and in vitro digestibility

(2016) Sean M. Tibbetts et al.   JOURNAL OF APPLIED PHYCOLOGY

Immunomodulatory Effects of the Mycosporine-Like Amino Acids Shinorine and Porphyra-334

(2016) Kathrin Becker et al.   Marine Drugs

Phlorotannins: Towards New Pharmacological Interventions for Diabetes Mellitus Type 2

(2016) Graciliana Lopes et al.   MOLECULES

Antiproliferative and Antioxidant Activities and Mycosporine-Like Amino Acid Profiles of Wild-Harvested and Cultivated Edible Canadian Marine Red Macroalgae

(2016) Yasantha Athukorala et al.   MOLECULES

A review of the components of brown seaweeds as potential candidates in cancer therapy

(2016) Ejaz Hussain et al.   RSC Advances

Synthesis of novel vinyl ester from biobased phloroglucinol

(2016) Fanny Jaillet et al.   Green Materials

Zonarol, a sesquiterpene from the brown algae Dictyopteris undulata , provides neuroprotection by activating the Nrf2/ARE pathway

(2015) Hiroya Shimizu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Marine bromophenol bis(2,3-dibromo-4,5-dihydroxybenzyl) ether, represses angiogenesis in HUVEC cells and in zebrafish embryos via inhibiting the VEGF signal systems

(2015) Xin Qi et al.   BIOMEDICINE & PHARMACOTHERAPY

Fucophlorethol C, a phlorotannin as a lipoxygenase inhibitor

(2015) Hideyuki Kurihara et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Dieckol, a phlorotannin ofEcklonia cava, suppresses IgE-mediated mast cell activation and passive cutaneous anaphylactic reaction

(2015) Ginnae Ahn et al.   EXPERIMENTAL DERMATOLOGY

6,6′-Bieckol protects insulinoma cells against high glucose-induced glucotoxicity by reducing oxidative stress and apoptosis

(2015) Mi-Hwa Park et al.   FITOTERAPIA

Dioxinodehydroeckol protects human keratinocyte cells from UVB-induced apoptosis modulated by related genes Bax/Bcl-2 and caspase pathway

(2015) BoMi Ryu et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

First Evidence that Ecklonia cava-Derived Dieckol Attenuates MCF-7 Human Breast Carcinoma Cell Migration

(2015) Eun-Kyung Kim et al.   Marine Drugs

Marine Bromophenol Bis (2,3-Dibromo-4,5-dihydroxy-phenyl)-methane Inhibits the Proliferation, Migration, and Invasion of Hepatocellular Carcinoma Cells via Modulating β1-Integrin/FAK Signaling

(2015) Ning Wu et al.   Marine Drugs

Phenolic Content and Antioxidant Capacity in Algal Food Products

(2015) Ludmila Machu et al.   MOLECULES

Seapolynol Extracted from Ecklonia cava Inhibits Adipocyte Differentiation in Vitro and Decreases Fat Accumulation in Vivo

(2015) Hui-Jeon Jeon et al.   MOLECULES

Bioactive compounds from brown seaweeds: Phloroglucinol, fucoxanthin and fucoidan as promising therapeutic agents against breast cancer

(2015) D. Pádua et al.   Phytochemistry Letters

Antiviral phlorotannin from Eisenia bicyclis against human papilloma virus in vitro

(2015) EB Kim et al.   PLANTA MEDICA

The anti-allergic activity of polyphenol extracted from five marine algae

(2015) Yu Chen et al.   Journal of Ocean University of China

In vitro antiviral activity of dieckol and phlorofucofuroeckol-A isolated from edible brown alga Eisenia bicyclis against murine norovirus

(2015) Sung-Hwan Eom et al.   ALGAE

Free Phenolic Acids from the Seaweed Halimeda monile with Antioxidant Effect Protecting against Liver Injury

(2015) Jorge Mancini-Filho et al.   ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES

6,6′-Bieckol Isolated from Ecklonia cava Protects Oxidative Stress Through Inhibiting Expression of ROS and Proinflammatory Enzymes in High-Glucose-Induced Human Umbilical Vein Endothelial Cells

(2014) Mi-Hwa Park et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Anti-HIV-1 activity of phlorotannin derivative 8,4‴-dieckol from Korean brown algaEcklonia cava

(2014) Fatih Karadeniz et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Phenolic Compounds and Plant Phenolic Extracts as Natural Antioxidants in Prevention of Lipid Oxidation in Seafood: A Detailed Review

(2014) Sajid Maqsood et al.   COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY

Algal extracts: Technology and advances

(2014) Izabela Michalak et al.   ENGINEERING IN LIFE SCIENCES

Dieckol, isolated from the edible brown algae Ecklonia cava, induces apoptosis of ovarian cancer cells and inhibits tumor xenograft growth

(2014) Ji-Hye Ahn et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Protective effect of the edible brown algaEcklonia stoloniferaon doxorubicin-induced hepatotoxicity in primary rat hepatocytes

(2014) Hyun Ah Jung et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Detection of flavonoids in microalgae from different evolutionary lineages

(2014) Koen Goiris et al.   JOURNAL OF PHYCOLOGY

Phlorotannins from Alaskan Seaweed Inhibit Carbolytic Enzyme Activity

(2014) Joshua Kellogg et al.   Marine Drugs

Bis(2,3-dibromo-4,5-dihydroxybenzyl) Ether, a Marine Algae Derived Bromophenol, Inhibits the Growth of Botrytis cinerea and Interacts with DNA Molecules

(2014) Ming Liu et al.   Marine Drugs

7-Phloroeckol promotes hair growth on human follicles in vitro

(2014) Soon-Sun Bak et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Dieckol, a SARS-CoV 3CLpro inhibitor, isolated from the edible brown algae Ecklonia cava

(2013) Ji-Young Park et al.   BIOORGANIC & MEDICINAL CHEMISTRY

In vitro antiviral activity of phlorotannins isolated from Ecklonia cava against porcine epidemic diarrhea coronavirus infection and hemagglutination

(2013) Hyung-Jun Kwon et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Application of Novel Extraction Technologies for Bioactives from Marine Algae

(2013) Shekhar U. Kadam et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Seaweeds for animal production use

(2013) F. D. Evans et al.   JOURNAL OF APPLIED PHYCOLOGY

Antioxidant activities and phenolic contents of three red seaweeds (Division: Rhodophyta) harvested from the Gulf of Mannar of Peninsular India

(2013) Kajal Chakraborty et al.   JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE

Benefits of polyphenols on gut microbiota and implications in human health

(2013) Fernando Cardona et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Antifungal Activity of Phlorotannins against Dermatophytes and Yeasts: Approaches to the Mechanism of Action and Influence on Candida albicans Virulence Factor

(2013) Graciliana Lopes et al.   PLoS One

Emerging Role of Phenolic Compounds as Natural Food Additives in Fish and Fish Products

(2012) Sajid Maqsood et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Antimicrobial effect of phlorotannins from marine brown algae

(2012) Sung-Hwan Eom et al.   FOOD AND CHEMICAL TOXICOLOGY

Phenolic compounds and antioxidant activities of selected species of seaweeds from Danish coast

(2012) K.H. Sabeena Farvin et al.   FOOD CHEMISTRY

Determination of major phlorotannins in Eisenia bicyclis using hydrophilic interaction chromatography: Seasonal variation and extraction characteristics

(2012) Sang Min Kim et al.   FOOD CHEMISTRY

Bioactive compounds extracted from Gamtae (Ecklonia cava) by using enzymatic hydrolysis, a potent α-glucosidase and α-amylase inhibitor, alleviates postprandial hyperglycemia in diabetic mice

(2012) Seung-Hong Lee et al.   FOOD SCIENCE AND BIOTECHNOLOGY

Isolation of a New Phlorotannin, a Potent Inhibitor of Carbohydrate-Hydrolyzing Enzymes, from the Brown Alga Sargassum patens

(2012) Yasuko Kawamura-Konishi et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Antioxidant Capacities of Phlorotannins Extracted from the Brown Algae Fucus vesiculosus

(2012) Tao Wang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Towards a better understanding of medicinal uses of the brown seaweed Sargassum in Traditional Chinese Medicine: A phytochemical and pharmacological review

(2012) Lei Liu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Dieckol, isolated from Ecklonia stolonifera, induces apoptosis in human hepatocellular carcinoma Hep3B cells

(2012) Jin-Soo Yoon et al.   Journal of Natural Medicines

Effect of different rehydration temperatures on the moisture, content of phenolic compounds, antioxidant capacity and textural properties of edible Irish brown seaweed

(2012) Sabrina Cox et al.   LWT-FOOD SCIENCE AND TECHNOLOGY

Phlorotannin Extracts from Fucales Characterized by HPLC-DAD-ESI-MSn: Approaches to Hyaluronidase Inhibitory Capacity and Antioxidant Properties

(2012) Federico Ferreres et al.   Marine Drugs

Cytotoxicity of fucosterol containing fraction of marine algae against breast and colon carcinoma cell line

(2012) SeyedNasser Ostad et al.   Pharmacognosy Magazine

Can Phlorotannins Purified Extracts Constitute a Novel Pharmacological Alternative for Microbial Infections with Associated Inflammatory Conditions?

(2012) Graciliana Lopes et al.   PLoS One

Marine bromophenol bis(2,3-dibromo-4,5-dihydroxybenzyl) ether, induces mitochondrial apoptosis in K562 cells and inhibits topoisomerase I in vitro

(2012) Ming Liu et al.   TOXICOLOGY LETTERS

Protein Tyrosine Phosphatase 1B and α-Glucosidase Inhibitory Phlorotannins from Edible Brown Algae,Ecklonia stoloniferaandEisenia bicyclis

(2011) Hye Eun MOON et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Algal chemodiversity and bioactivity: Sources of natural variability and implications for commercial application

(2011) Dagmar B. Stengel et al.   BIOTECHNOLOGY ADVANCES

Challenges of Antibacterial Discovery

(2011) L. L. Silver   CLINICAL MICROBIOLOGY REVIEWS

Potential pharmacological applications of polyphenolic derivatives from marine brown algae

(2011) Noel Vinay Thomas et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Polyphenol-rich seaweed (Eucheuma cottonii) extract suppresses breast tumour via hormone modulation and apoptosis induction

(2011) Farideh Namvar et al.   FOOD CHEMISTRY

Effect of a commercially-available algal phlorotannins extract on digestive enzymes and carbohydrate absorption in vivo

(2011) Marie-Claude Roy et al.   FOOD RESEARCH INTERNATIONAL

Recent developments in the application of seaweeds or seaweed extracts as a means for enhancing the safety and quality attributes of foods

(2011) Shilpi Gupta et al.   Innovative Food Science & Emerging Technologies

Exploiting biological activities of brown seaweedEcklonia cavafor potential industrial applications: a review

(2011) W. A. J. P. Wijesinghe et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION

Influenza Virus Neuraminidase Inhibitory Activity of Phlorotannins from the Edible Brown AlgaEcklonia cava

(2011) Young Bae Ryu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Antioxidant Potential of Two Red Seaweeds from the Brazilian Coasts

(2011) Bartolomeu W. S. Souza et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Bioactive compounds in seaweed: functional food applications and legislation

(2011) Susan Løvstad Holdt et al.   JOURNAL OF APPLIED PHYCOLOGY

CYTOTOXIC ACTIVITIES OF PHLORETHOL AND FUCOPHLORETHOL DERIVATIVES ISOLATED FROM LAMINARIACEAE ECKLONIA CAVA

(2011) YONG LI et al.   JOURNAL OF FOOD BIOCHEMISTRY

In Vitro antiviral activity of red alga, Polysiphonia morrowii extract and its bromophenols against fish pathogenic infectious hematopoietic necrosis virus and infectious pancreatic necrosis virus

(2011) Su-Yeun Kim et al.   JOURNAL OF MICROBIOLOGY

Anti-Proliferative Activity of Meroditerpenoids Isolated from the Brown Alga Stypopodium flabelliforme against Several Cancer Cell Lines

(2011) David M. Pereira et al.   Marine Drugs

Mycosporine-Like Amino Acids: Relevant Secondary Metabolites. Chemical and Ecological Aspects

(2011) Jose I. Carreto et al.   Marine Drugs

Bromophenols in Marine Algae and Their Bioactivities

(2011) Ming Liu et al.   Marine Drugs

Neuroprotective Effects of Marine Algae

(2011) Ratih Pangestuti et al.   Marine Drugs

In Vitro Anti-HMPV Activity of Meroditerpenoids from Marine Alga Stypopodium zonale (Dictyotales)

(2011) Gabriella Mendes et al.   MOLECULES

Effect of phlorotannins isolated fromEcklonia cavaon angiotensin I-converting enzyme (ACE) inhibitory activity

(2011) W.A.J.P. Wijesinghe et al.   Nutrition Research and Practice

Phlorotannins as bioactive agents from brown algae

(2011) Yong-Xin Li et al.   PROCESS BIOCHEMISTRY

Phlorofucofuroeckol A inhibits the LPS-stimulated iNOS and COX-2 expressions in macrophages via inhibition of NF-κB, Akt, and p38 MAPK

(2011) A.-Reum Kim et al.   TOXICOLOGY IN VITRO

Prebiotic evaluation of cocoa-derived flavanols in healthy humans by using a randomized, controlled, double-blind, crossover intervention study

(2010) Xenofon Tzounis et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Novel determination of the total phenolic content in crude plant extracts by the use of 1H NMR of the –OH spectral region

(2010) A.A. Nerantzaki et al.   ANALYTICA CHIMICA ACTA

Challenges of antibacterial discovery revisited

(2010) Michael N. Gwynn et al.   Annals of the New York Academy of Sciences

Phlorotannins from Ecklonia cava (Phaeophyceae): Biological activities and potential health benefits

(2010) Isuru Wijesekara et al.   BIOFACTORS

Unusual antimalarial meroditerpenes from tropical red macroalgae

(2010) E. Paige Stout et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Molecular docking studies of phlorotannins from Eisenia bicyclis with BACE1 inhibitory activity

(2010) Hyun Ah Jung et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Highly brominated metabolites from marine red alga Laurencia similis inhibit protein tyrosine phosphatase 1B

(2010) Jianchun Qin et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Antithrombotic effects of bromophenol, an alga-derived thrombin inhibitor

(2010) Dayong Shi et al.   CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY

Hypertension, Nitric Oxide, Oxidants, and Dietary Plant Polyphenols

(2010) Monica Galleano et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Dieckol isolated from Ecklonia cava inhibits α-glucosidase and α-amylase in vitro and alleviates postprandial hyperglycemia in streptozotocin-induced diabetic mice

(2010) Seung-Hong Lee et al.   FOOD AND CHEMICAL TOXICOLOGY

Inhibition of haemoglobin-mediated lipid oxidation in washed cod muscle and cod protein isolates by Fucus vesiculosus extract and fractions

(2010) Tao Wang et al.   FOOD CHEMISTRY

Total phenolic contents, radical scavenging and cyclic voltammetry of seaweeds from Brittany

(2010) R. Keyrouz et al.   FOOD CHEMISTRY

Anti-proliferative and potential anti-diabetic effects of phenolic-rich extracts from edible marine algae

(2010) Felix Nwosu et al.   FOOD CHEMISTRY

Facts about the formation of new antioxidants in natural samples after subcritical water extraction

(2010) Merichel Plaza et al.   FOOD RESEARCH INTERNATIONAL

Bioavailability of the Polyphenols: Status and Controversies

(2010) Massimo D’Archivio et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Seaweed extract stimuli in plant science and agriculture

(2010) James S. Craigie   JOURNAL OF APPLIED PHYCOLOGY

Anti-inflammatory properties of phenolic compounds and crude extract from Porphyra dentata

(2010) Katarzyna Kazłowska et al.   JOURNAL OF ETHNOPHARMACOLOGY

The Antioxidant Properties of Ethanol Extracts and Their Solvent-Partitioned Fractions from Various Green Seaweeds

(2010) MyoungLae Cho et al.   JOURNAL OF MEDICINAL FOOD

Antifungal Activities of Dieckol Isolated from the Marine Brown Alga Ecklonia cava against Trichophyton rubrum

(2010) Min Hee Lee   Journal of the Korean Society for Applied Biological Chemistry

Distribution and Abundance of MAAs in 33 Species of Microalgae across 13 Classes

(2010) Carole Anne Llewellyn et al.   Marine Drugs

Anticancer Agents Derived from Natural Products

(2010) E-Hu Liu et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Plant Phenolics: Extraction, Analysis and Their Antioxidant and Anticancer Properties

(2010) Jin Dai et al.   MOLECULES

Polyphenols: Chemistry, Dietary Sources, Metabolism, and Nutritional Significance

(2010) Laura Bravo   NUTRITION REVIEWS

Seaweeds as a source of lead compounds for the development of new antiplasmodial drugs from South East coast of India

(2010) Sundaram Ravikumar et al.   PARASITOLOGY RESEARCH

Phenolic compounds in the brown seaweed Ascophyllum nodosum: distribution and radical-scavenging activities

(2010) Laetitia Audibert et al.   PHYTOCHEMICAL ANALYSIS

Inhibitory effects of phloroglucinol derivatives isolated from Ecklonia stolonifera on FcεRI expression

(2009) Sun-Yup Shim et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synergistic effect between dieckol from Ecklonia stolonifera and β-lactams against methicillin-resistant Staphylococcus aureus

(2009) Dae-Sung Lee et al.   BIOTECHNOLOGY AND BIOPROCESS ENGINEERING

Differentiation of human osteosarcoma cells by isolated phlorotannins is subtly linked to COX-2, iNOS, MMPs, and MAPK signaling: Implication for chronic articular disease

(2009) BoMi Ryu et al.   CHEMICO-BIOLOGICAL INTERACTIONS

The antitumor effect of bromophenol derivatives in vitro and Leathesia nana extract in vivo

(2009) Dayong Shi et al.   CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY

Discovery of Lignin in Seaweed Reveals Convergent Evolution of Cell-Wall Architecture

(2009) Patrick T. Martone et al.   CURRENT BIOLOGY

Induction of apoptosis by phloroglucinol derivative from Ecklonia Cava in MCF-7 human breast cancer cells

(2009) Chang-Suk Kong et al.   FOOD AND CHEMICAL TOXICOLOGY

Total phenolic compounds, radical scavenging and metal chelation of extracts from Icelandic seaweeds

(2009) Tao Wang et al.   FOOD CHEMISTRY

Antibacterial Activity of Ecklonia cava Against Methicillin-Resistant Staphylococcus aureus and Salmonella spp.

(2009) Jang-Gi Choi et al.   Foodborne Pathogens and Disease

Isolation and Identification of Phlorotannins fromEcklonia stoloniferawith Antioxidant and Anti-inflammatory Properties

(2009) A-Reum Kim et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Inhibitory Effect of Phlorotannins Isolated from Ecklonia cava on Mushroom Tyrosinase Activity and Melanin Formation in Mouse B16F10 Melanoma Cells

(2009) Na Young Yoon et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Antimalarial Bromophycolides J−Q from the Fijian Red AlgaCallophycus serratus

(2009) Amy L. Lane et al.   JOURNAL OF ORGANIC CHEMISTRY

Bioactive phenols in algae: The application of pressurized-liquid and solid-phase extraction techniques

(2009) L. Onofrejová et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Meroditerpenoids from the southern Australian marine brown alga Sargassum fallax

(2009) Priyanka Reddy et al.   PHYTOCHEMISTRY

Coral Skeletons Defend against Ultraviolet Radiation

(2009) Ruth Reef et al.   PLoS One

Colensolide A: a new nitrogenous bromophenol from the New Zealand marine red alga Osmundaria colensoi

(2009) Wendy L. Popplewell et al.   TETRAHEDRON LETTERS

Effect of phlorotannins isolated from Ecklonia cava on melanogenesis and their protective effect against photo-oxidative stress induced by UV-B radiation

(2009) Soo-Jin Heo et al.   TOXICOLOGY IN VITRO

Modulation of apoptosis of eckol against ionizing radiation in mice

(2008) Eunjin Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Anti-HIV-1 activity of phloroglucinol derivative, 6,6′-bieckol, from Ecklonia cava

(2008) Murat Artan et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Eckol protects V79-4 lung fibroblast cells against γ-ray radiation-induced apoptosis via the scavenging of reactive oxygen species and inhibiting of the c-Jun NH2-terminal kinase pathway

(2008) Rui Zhang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Mycosporine-like amino acid composition of the edible red alga, Palmaria palmata (dulse) harvested from the west and east coasts of Grand Manan Island, New Brunswick

(2008) Yvonne V. Yuan et al.   FOOD CHEMISTRY

Synthesized phosphorylated and aminated derivatives of fucoidan and their potential antioxidant activity in vitro

(2008) Jing Wang et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Inhibition of Listeria monocytogenes by oregano, cranberry and sodium lactate combination in broth and cooked ground beef systems and likely mode of action through proline metabolism

(2008) E. Apostolidis et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Antioxidant activities and phenolics content of eight species of seaweeds from north Borneo

(2008) Patricia Matanjun et al.   JOURNAL OF APPLIED PHYCOLOGY

Antithrombotic effect of bromophenol, the alga-derived thrombin inhibitor

(2008) Dayong Shi et al.   JOURNAL OF BIOTECHNOLOGY

Meroditerpenoids and Derivatives from the Brown AlgaCystoseira baccataand Their Antifouling Properties

(2008) Redouane Mokrini et al.   JOURNAL OF NATURAL PRODUCTS

Antifouling Activity of Meroditerpenoids from the Marine Brown AlgaHalidrys siliquosa

(2008) Gérald Culioli et al.   JOURNAL OF NATURAL PRODUCTS

Potent α-glucosidase inhibitors purified from the red alga Grateloupia elliptica

(2008) K.Y. Kim et al.   PHYTOCHEMISTRY

Inhibition of bromophenols against PTP1B and anti-hyperglycemic effect of Rhodomela confervoides extract in diabetic rats

(2008) DaYong Shi et al.   Science Bulletin

Effects of phlorotannins from Ascophyllum nodosum (brown seaweed) on in vitro ruminal digestion of mixed forage or barley grain

(2007) Y. Wang et al.   ANIMAL FEED SCIENCE AND TECHNOLOGY

Effect of feeding sun-dried seaweed (Ascophyllum nodosum) on fecal shedding of Escherichia coli O157:H7 by feedlot cattle and on growth performance of lambs

(2007) S.J. Bach et al.   ANIMAL FEED SCIENCE AND TECHNOLOGY

Antioxidant properties of methanol extract and its solvent fractions obtained from selected Indian red seaweeds

(2007) P. Ganesan et al.   BIORESOURCE TECHNOLOGY

Protective effect of phlorotannin components phloroglucinol and eckol on radiation-induced intestinal injury in mice

(2007) Changjong Moon et al.   PHYTOTHERAPY RESEARCH