α-Glucosidase and Protein Tyrosine Phosphatase 1B Inhibitory Activity of Plastoquinones from Marine Brown Alga Sargassum serratifolium

Photo-protective effect of sargachromenol against UVB radiation-induced damage through modulating cellular antioxidant systems and apoptosis in human keratinocytes

(2016) Pattage Madushan Dilhara Jayatissa Fernando et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Anti-inflammatory action of the ethanolic extract from Sargassum serratifolium on lipopolysaccharide-stimulated mouse peritoneal macrophages and identification of active components

(2016) Eun-Ji Joung et al.   JOURNAL OF APPLIED PHYCOLOGY

Marine Organisms with Anti-Diabetes Properties

(2016) Chiara Lauritano et al.   Marine Drugs

Fucoidan – A α-d-glucosidase inhibitor from Sargassum wightii with relevance to type 2 diabetes mellitus therapy

(2015) T. Vinoth Kumar et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Sargaquinoic Acid Inhibits TNF-α-Induced NF-κB Signaling, Thereby Contributing to Decreased Monocyte Adhesion to Human Umbilical Vein Endothelial Cells (HUVECs)

(2015) Wi-Gyeong Gwon et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Small Molecules as Potent Protein Tyrosine Phosphatase 1B (PTP1B) Inhibitors Documented in Patents from 2009 to 2013

(2015) Li-Jun Wang et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Hexane extract from Sargassum serratifolium inhibits the cell proliferation and metastatic ability of human glioblastoma U87MG cells

(2015) CHANG-WON KANG et al.   ONCOLOGY REPORTS

Protein-tyrosine phosphatase 1B substrates and metabolic regulation

(2015) Jesse Bakke et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Sargahydroquinoic acid inhibits TNFα-induced AP-1 and NF-κB signaling in HaCaT cells through PPARα activation

(2014) Youngsic Jeon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Thunberol, a new sterol from the Chinese brown algaSargassum thunbergii

(2014) Wen-Fei He et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Targeting the disordered C terminus of PTP1B with an allosteric inhibitor

(2014) Navasona Krishnan et al.   Nature Chemical Biology

α-Glucosidase inhibition by luteolin: Kinetics, interaction and molecular docking

(2013) Jiakai Yan et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Sargachromenol fromSargassum micracanthumInhibits the Lipopolysaccharide-Induced Production of Inflammatory Mediators in RAW 264.7 Macrophages

(2013) Eun-Jin Yang et al.   TheScientificWorldJOURNAL

Mini-Special Issue paper Management of diabetic patients with hypoglycemic agents α-Glucosidase inhibitors and their use in clinical practice

(2012) Giuseppe Derosa et al.   Archives of Medical Science

Anti-diabetic and hypolipidemic effects of Sargassum yezoense in db/db mice

(2012) Su-Nam Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Sargaquinoic acid isolated fromSargassum siliquastruminhibits lipopolysaccharide-induced nitric oxide production in macrophagesviamodulation of nuclear factor-κB and c-JunN-terminal kinase pathways

(2012) Gyeoung-Jin Kang et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Quinones and halogenated monoterpenes of algal origin show anti-proliferative effects against breast cancer cells in vitro

(2012) Jo-Anne de la Mare et al.   INVESTIGATIONAL NEW DRUGS

Towards a better understanding of medicinal uses of the brown seaweed Sargassum in Traditional Chinese Medicine: A phytochemical and pharmacological review

(2012) Lei Liu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Marine Bioactives: Pharmacological Properties and Potential Applications against Inflammatory Diseases

(2012) Nicolantonio D’Orazio et al.   Marine Drugs

Liver-specific deletion of protein tyrosine phosphatase (PTP) 1B improves obesity- and pharmacologically induced endoplasmic reticulum stress

(2011) Abdelali Agouni et al.   BIOCHEMICAL JOURNAL

Potential pharmacological applications of polyphenolic derivatives from marine brown algae

(2011) Noel Vinay Thomas et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Antidiabetic activity of some pentacyclic acid triterpenoids, role of PTP–1B: In vitro, in silico, and in vivo approaches

(2011) Juan José Ramírez-Espinosa et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Discovery of novel PTP1B inhibitors with antihyperglycemic activity

(2010) Zhang Liu et al.   ACTA PHARMACOLOGICA SINICA

Occurrence, biosynthesis and function of isoprenoid quinones

(2010) Beatrycze Nowicka et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Diphlorethohydroxycarmalol isolated from Ishige okamurae, a brown algae, a potent α-glucosidase and α-amylase inhibitor, alleviates postprandial hyperglycemia in diabetic mice

(2009) Soo-Jin Heo et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Protein Tyrosine Phosphorylation and Protein Tyrosine Nitration in Redox Signaling

(2008) Hugo P. Monteiro et al.   ANTIOXIDANTS & REDOX SIGNALING

Selective vasodilatation effect of sargahydroquinoic acid, an active constituent of Sargassum micracanthum, on the basilar arteries of rabbits

(2008) Byong-Gon Park et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Sargaquinoic acid and sargachromenol, extracts of Sargassum sagamianum, induce apoptosis in HaCaT cells and mice skin: Its potentiation of UVB-induced apoptosis

(2008) Seulgi Hur et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Sargaquinoic acid and sargahydroquinoic acid fromSargassum yezoensestimulate adipocyte differentiation through PPARα/γ activation in 3T3-L1 cells

(2008) Su-Nam Kim et al.   FEBS LETTERS

Inhibitory activities of extracts from several kinds of seaweeds and phlorotannins from the brown algaEcklonia stoloniferaon glucose-mediated protein damage and rat lens aldose reductase

(2008) Hyun Ah JUNG et al.   FISHERIES SCIENCE