Multifaceted TGF‐β signaling, a master regulator: From bench‐to‐bedside, intricacies, and complexities
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Title
Multifaceted TGF‐β signaling, a master regulator: From bench‐to‐bedside, intricacies, and complexities
Authors
Keywords
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Journal
CELL BIOLOGY INTERNATIONAL
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2023-10-20
DOI
10.1002/cbin.12097
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Note: Only part of the references are listed.- Cancer‐associated fibroblasts: Is it a key to an intricate lock of tumorigenesis?
- (2023) Durre Aden et al. CELL BIOLOGY INTERNATIONAL
- Efficacy of therapies targeting TGF-β in solid tumors: a systematic review and meta-analysis of clinical trials
- (2023) Hossein Rahavi et al. Immunotherapy
- PHF14 enhances DNA methylation of SMAD7 gene to promote TGF-β-driven lung adenocarcinoma metastasis
- (2023) Han Tian et al. Cell Discovery
- The Effect of Hypoxia and Hypoxia-Associated Pathways in the Regulation of Antitumor Response: Friends or Foes?
- (2022) Raefa Abou Khouzam et al. Frontiers in Immunology
- A Tight Control of Non-Canonical TGF-β Pathways and MicroRNAs Downregulates Nephronectin in Podocytes
- (2022) Nina Sopel et al. Cells
- Transforming growth factor-beta (TGF-β) in prostate cancer: A dual function mediator?
- (2022) Sepideh Mirzaei et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- Targeting TGF-β signal transduction for fibrosis and cancer therapy
- (2022) Dandan Peng et al. Molecular Cancer
- Transforming Growth Factor-Beta (TGF-β) Signaling in Cancer-A Betrayal Within
- (2022) Abdul Basit Baba et al. Frontiers in Pharmacology
- The Love-Hate Relationship Between TGF-β Signaling and the Immune System During Development and Tumorigenesis
- (2022) Baode Chen et al. Frontiers in Immunology
- Tumor-derived small extracellular vesicles: potential roles and mechanism in glioma
- (2022) Xu Guo et al. JOURNAL OF NANOBIOTECHNOLOGY
- TGFβ-derived immune modulatory vaccine: targeting the immunosuppressive and fibrotic tumor microenvironment in a murine model of pancreatic cancer
- (2022) Maria Perez-Penco et al. Journal for ImmunoTherapy of Cancer
- TGF-β1 promotes human breast cancer angiogenesis and malignant behavior by regulating endothelial-mesenchymal transition
- (2022) Zi-Xiong Li et al. Frontiers in Oncology
- TGFβ + small extracellular vesicles from head and neck squamous cell carcinoma cells reprogram macrophages towards a pro‐angiogenic phenotype
- (2022) Nils Ludwig et al. Journal of Extracellular Vesicles
- TGF-β in Cancer: Metabolic Driver of the Tolerogenic Crosstalk in the Tumor Microenvironment
- (2021) Roberta Angioni et al. Cancers
- Organ Fibrosis and Autoimmunity: The Role of Inflammation in TGFβ-Dependent EMT
- (2021) Margherita Sisto et al. Biomolecules
- TGF-β1 Signaling: Immune Dynamics of Chronic Kidney Diseases
- (2021) Philip Chiu-Tsun Tang et al. Frontiers in Medicine
- Whole-organ analysis of TGF-β-mediated remodelling of the tumour microenvironment by tissue clearing
- (2021) Shimpei I. Kubota et al. Communications Biology
- Novel therapies emerging in oncology to target the TGF-β pathway
- (2021) Byung-Gyu Kim et al. Journal of Hematology & Oncology
- TGF-β Signaling: From Tissue Fibrosis to Tumor Microenvironment
- (2021) Jeff Yat-Fai Chung et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- DNA Methylation of TGFβ Target Genes: Epigenetic Control of TGFβ Functional Duality in Liver Cancer
- (2021) Kevin Bévant et al. Cells
- Smad3 Promotes Cancer‐Associated Fibroblasts Generation via Macrophage–Myofibroblast Transition
- (2021) Philip Chiu‐Tsun Tang et al. Advanced Science
- Regulation of Partial and Reversible Endothelial-to-Mesenchymal Transition in Angiogenesis
- (2021) Jennifer S. Fang et al. Frontiers in Cell and Developmental Biology
- TGF-β Signaling and Resistance to Cancer Therapy
- (2021) Maoduo Zhang et al. Frontiers in Cell and Developmental Biology
- Transforming growth factor–β in tissue fibrosis
- (2020) Nikolaos G. Frangogiannis JOURNAL OF EXPERIMENTAL MEDICINE
- Differential expression and localisation of TGF-β isoforms and receptors in the murine epididymis
- (2020) Allison Voisin et al. Scientific Reports
- Pyruvate Kinase M2 and Cancer: The Role of PKM2 in Promoting Tumorigenesis
- (2020) Kulsoom Zahra et al. Frontiers in Oncology
- Tumor microenvironment complexity and therapeutic implications at a glance
- (2020) Roghayyeh Baghban et al. Cell Communication and Signaling
- TGF-β-Induced Endothelial to Mesenchymal Transition in Disease and Tissue Engineering
- (2020) Jin Ma et al. Frontiers in Cell and Developmental Biology
- TGF-β Signaling
- (2020) Kalliopi Tzavlaki et al. Biomolecules
- Epithelial-Mesenchymal Transition in Cancer: A Historical Overview
- (2020) Domenico Ribatti et al. Translational Oncology
- TGF-β induced EMT and stemness characteristics are associated with epigenetic regulation in lung cancer
- (2020) Bit Na Kim et al. Scientific Reports
- MiR-216b/Smad3/BCL-2 Axis Is Involved in Smoking-Mediated Drug Resistance in Non-Small Cell Lung Cancer
- (2020) Trung Vu et al. Cancers
- On-Target Anti-TGF-β Therapies Are Not Succeeding in Clinical Cancer Treatments: What Are Remaining Challenges?
- (2020) Adilson Fonseca Teixeira et al. Frontiers in Cell and Developmental Biology
- Long noncoding RNA H19X is a key mediator of TGF-β–driven fibrosis
- (2020) Elena Pachera et al. JOURNAL OF CLINICAL INVESTIGATION
- Epigenetic and breast cancer therapy: Promising diagnostic and therapeutic applications
- (2020) Gulab Sher et al. SEMINARS IN CANCER BIOLOGY
- Endothelial-to-Mesenchymal Transition in Cancer
- (2020) Nicolas Clere et al. Frontiers in Cell and Developmental Biology
- Discovery of VEGFR-2 inhibitors exerting significant anticancer activity against CD44+ and CD133+ cancer stem cells (CSCs): Reversal of TGF-β induced epithelial-mesenchymal transition (EMT) in hepatocellular carcinoma
- (2020) Siddharth J. Modi et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- The Roles of Matrix Metalloproteinases and Their Inhibitors in Human Diseases
- (2020) Griselda A Cabral-Pacheco et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Pathological Insight into 5-HT2B Receptor Activation in Fibrosing Interstitial Lung Diseases
- (2020) Anna Löfdahl et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Canonical and noncanonical TGF-β signaling regulate fibrous tissue differentiation in the axial skeleton
- (2020) Sade W. Clayton et al. Scientific Reports
- Transforming Growth Factor-β Signaling in Fibrotic Diseases and Cancer-Associated Fibroblasts
- (2020) Xueke Shi et al. Biomolecules
- Role of TGF-Beta and Smad7 in Gut Inflammation, Fibrosis and Cancer
- (2020) Carmine Stolfi et al. Biomolecules
- Modulation of the TGF-β signaling pathway by long noncoding RNA in hepatocellular carcinoma
- (2020) Mengzhen Han et al. Biomarker Research
- Recent progress in TGF-β inhibitors for cancer therapy
- (2020) Cheng-Yi Huang et al. BIOMEDICINE & PHARMACOTHERAPY
- Efficacy and Effectiveness Too (EE2) Trials:Clinical Trial Designs to Generate Evidence on Efficacy and on Effectiveness in Wide Practice
- (2019) Harry P Selker et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- α-PD-1 therapy elevates Treg/Th balance and increases tumor cell pSmad3 that are both targeted by α-TGFβ antibody to promote durable rejection and immunity in squamous cell carcinomas
- (2019) E. Dodagatta-Marri et al. Journal for ImmunoTherapy of Cancer
- The Molecular Mechanism of Transforming Growth Factor-β Signaling for Intestinal Fibrosis: A Mini-Review
- (2019) Sun-Mi Yun et al. Frontiers in Pharmacology
- Chronic TGF-β exposure drives stabilized EMT, tumor stemness, and cancer drug resistance with vulnerability to bitopic mTOR inhibition
- (2019) Yoko Katsuno et al. Science Signaling
- Specificity, versatility, and control of TGF-β family signaling
- (2019) Rik Derynck et al. Science Signaling
- Long non-coding RNA PVT1 promotes tumor progression by regulating the miR-143/HK2 axis in gallbladder cancer
- (2019) Jianan Chen et al. Molecular Cancer
- Mechanical regulation of myofibroblast phenoconversion and collagen contraction
- (2019) Boris Hinz et al. EXPERIMENTAL CELL RESEARCH
- The Long Non-Coding RNA DNM3OS is a Reservoir of FibromiRs with Major Functions in Lung Fibroblast Response to TGF-β and Pulmonary Fibrosis
- (2019) Grégoire Savary et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
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- (2019) Tian Wang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Endothelial to Mesenchymal Transition: Role in Physiology and in the Pathogenesis of Human Diseases
- (2019) Sonsoles Piera-Velazquez et al. PHYSIOLOGICAL REVIEWS
- Epigenetic Reprogramming of TGF-β Signaling in Breast Cancer
- (2019) Suriyamurthy et al. Cancers
- The Tumor Metabolic Microenvironment: Lessons from Lactate
- (2019) Juan C. García-Cañaveras et al. CANCER RESEARCH
- PAR2 Inhibition Enhanced the Sensitivity of Colorectal Cancer Cells to 5-FU and Reduced EMT Signaling
- (2019) Qiuying Quan et al. ONCOLOGY RESEARCH
- Transcriptional regulation of autophagy-lysosomal function in BRAF-driven melanoma progression and chemoresistance
- (2019) Shun Li et al. Nature Communications
- Preclinical Evidence of STAT3 Inhibitor Pacritinib Overcoming Temozolomide Resistance via Downregulating miR-21-Enriched Exosomes from M2 Glioblastoma-Associated Macrophages
- (2019) Hao-Yu Chuang et al. Journal of Clinical Medicine
- BRG1 regulates endothelial-derived IL-33 to promote ischemia-reperfusion induced renal injury and fibrosis in mice
- (2019) Li Liu et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- TGF-β induced chemoresistance in liver cancer is modulated by xenobiotic nuclear receptor PXR
- (2019) Ella Bhagyaraj et al. CELL CYCLE
- Structural biology of betaglycan and endoglin, membrane-bound co-receptors of the TGF-beta family
- (2019) Sun Kyung Kim et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- The Effects of TGF-β Signaling on Cancer Cells and Cancer Stem Cells in the Bone Microenvironment
- (2019) Mitsuru Futakuchi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The Role of Matrix Metalloproteinases in the Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma
- (2019) Cristian Scheau et al. Analytical Cellular Pathology
- ID1 Mediates Escape from TGFβ Tumor Suppression in Pancreatic Cancer
- (2019) Yun-Han Huang et al. Cancer Discovery
- Hepatocyte growth factor attenuates the development of TGF-β1-induced EndMT through down-regulating the Notch signaling
- (2019) Ruiping Yang et al. Endocrine Metabolic & Immune Disorders-Drug Targets
- TGFβ induces stemness through non-canonical AKT-FOXO3a axis in oral squamous cell carcinoma
- (2019) Kan Li et al. EBioMedicine
- Lactate in the Regulation of Tumor Microenvironment and Therapeutic Approaches
- (2019) Karen G. de la Cruz-López et al. Frontiers in Oncology
- The Chromatin Remodeler Brg1 Integrates ROS Production and Endothelial-Mesenchymal Transition to Promote Liver Fibrosis in Mice
- (2019) Zilong Li et al. Frontiers in Cell and Developmental Biology
- A Perspective on the Development of TGF-β Inhibitors for Cancer Treatment
- (2019) Huynh et al. Biomolecules
- Molecular mechanisms of epithelial to mesenchymal transition in tumor metastasis
- (2019) Artur Nieszporek et al. ACTA BIOCHIMICA POLONICA
- Hexokinase 2 couples glycolysis with the profibrotic actions of TGF-β
- (2019) Xueqian Yin et al. Science Signaling
- Non-canonical (non-SMAD2/3) TGF-β signaling in fibrosis: Mechanisms and targets
- (2019) Kenneth W. Finnson et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Role of Matrix Metalloproteinases in Angiogenesis and Cancer
- (2019) Saray Quintero-Fabián et al. Frontiers in Oncology
- OUP accepted manuscript
- (2018) ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- Effects of 5-Hydroxytryptamine Class 2 Receptor Antagonists on Bronchoconstriction and Pulmonary Remodeling Processes
- (2018) Anna Löfdahl et al. AMERICAN JOURNAL OF PATHOLOGY
- TGF-β signaling promotes tumor vasculature by enhancing the pericyte-endothelium association
- (2018) Justin Zonneville et al. BMC CANCER
- miR-200c inhibits TGF-β-induced-EMT to restore trastuzumab sensitivity by targeting ZEB1 and ZEB2 in gastric cancer
- (2018) Xinliang Zhou et al. CANCER GENE THERAPY
- Long non-coding RNA XIST promotes TGF-β-induced epithelial-mesenchymal transition by regulating miR-367/141-ZEB2 axis in non-small-cell lung cancer
- (2018) Chang Li et al. CANCER LETTERS
- The role of transforming growth factor β in T helper 17 differentiation
- (2018) Song Zhang IMMUNOLOGY
- TGF-β and the Tissue Microenvironment: Relevance in Fibrosis and Cancer
- (2018) Laia Caja et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The Balance of Th17 versus Treg Cells in Autoimmunity
- (2018) Gap Lee INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Upregulation of lactate-inducible snail protein suppresses oncogene-mediated senescence through p16INK4a inactivation
- (2018) Xiangrui Li et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Transforming growth factor-β signalling in renal fibrosis: from Smads to non-coding RNAs
- (2018) Patrick Ming-Kuen Tang et al. JOURNAL OF PHYSIOLOGY-LONDON
- Targeting TGF-β signaling for the treatment of fibrosis
- (2018) Andrea Hermina Györfi et al. MATRIX BIOLOGY
- Paracrine and epigenetic control of CAF-induced metastasis: the role of HOTAIR stimulated by TGF-ß1 secretion
- (2018) Yu Ren et al. Molecular Cancer
- TGFβ drives immune evasion in genetically reconstituted colon cancer metastasis
- (2018) Daniele V. F. Tauriello et al. NATURE
- Contextual determinants of TGFβ action in development, immunity and cancer
- (2018) Charles J. David et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Lineage specific transcription factors and epigenetic regulators mediate TGFβ-dependent enhancer activation
- (2018) Raquel Fueyo et al. NUCLEIC ACIDS RESEARCH
- Safer approaches to therapeutic modulation of TGF-β signaling for respiratory disease
- (2018) Philippe Lachapelle et al. PHARMACOLOGY & THERAPEUTICS
- Enhanced preclinical antitumor activity of M7824, a bifunctional fusion protein simultaneously targeting PD-L1 and TGF-β
- (2018) Yan Lan et al. Science Translational Medicine
- Resveratrol inhibits the growth of gastric cancer via the Wnt/β-catenin pathway
- (2018) Hui Dai et al. Oncology Letters
- Bifunctional immune checkpoint-targeted antibody-ligand traps that simultaneously disable TGFβ enhance the efficacy of cancer immunotherapy
- (2018) Rajani Ravi et al. Nature Communications
- Metabolic Reprogramming of Cancer Associated Fibroblasts: The Slavery of Stromal Fibroblasts
- (2018) Angelica Avagliano et al. Biomed Research International
- Casein Kinase 1δ/ε Inhibitor, PF670462 Attenuates the Fibrogenic Effects of Transforming Growth Factor-β in Pulmonary Fibrosis
- (2018) Christine R. Keenan et al. Frontiers in Pharmacology
- Fibroblast growth factor–transforming growth factor beta dialogues, endothelial cell to mesenchymal transition, and atherosclerosis
- (2018) Pei-Yu Chen et al. CURRENT OPINION IN LIPIDOLOGY
- TGF-β/SMAD4-Regulated LncRNA-LINP1 Inhibits Epithelial-Mesenchymal Transition in Lung Cancer
- (2018) Chong Zhang et al. International Journal of Biological Sciences
- TGF-β Signaling in Lung Health and Disease
- (2018) Akira Saito et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells
- (2018) Sanjeev Mariathasan et al. NATURE
- The long noncoding RNA NORAD enhances the TGF‐β pathway to promote hepatocellular carcinoma progression by targeting miR‐202‐5p
- (2018) Xuan Yang et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Targeting FOXA1-mediated repression of TGF-β signaling suppresses castration-resistant prostate cancer progression
- (2018) Bing Song et al. JOURNAL OF CLINICAL INVESTIGATION
- SMAD4 promotes TGF-β–independent NK cell homeostasis and maturation and antitumor immunity
- (2018) Youwei Wang et al. JOURNAL OF CLINICAL INVESTIGATION
- Effects of tumor metabolic microenvironment on regulatory T cells
- (2018) Yi-an Wang et al. Molecular Cancer
- TGFβ Blockade Augments PD-1 Inhibition to Promote T-Cell Mediated Regression of Pancreatic Cancer
- (2018) Daniel R Principe et al. MOLECULAR CANCER THERAPEUTICS
- TGF-β-associated extracellular matrix genes link cancer-associated fibroblasts to immune evasion and immunotherapy failure
- (2018) Ankur Chakravarthy et al. Nature Communications
- TGFβ as a therapeutic target in cystic fibrosis
- (2017) Elizabeth L. Kramer et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- TGF-β1 targets Smad, p38 MAPK, and PI3K/Akt signaling pathways to induce PFKFB3 gene expression and glycolysis in glioblastoma cells
- (2017) Ana Rodríguez-García et al. FEBS Journal
- TGFβ signaling and the control of myofibroblast differentiation: Implications for chronic inflammatory disorders
- (2017) Jonathon M. Carthy JOURNAL OF CELLULAR PHYSIOLOGY
- MicroRNA-125a promotes resistance to BRAF inhibitors through suppression of the intrinsic apoptotic pathway
- (2017) Lisa Koetz-Ploch et al. Pigment Cell & Melanoma Research
- TGF-β1 Signaling and Tissue Fibrosis
- (2017) Kevin K. Kim et al. Cold Spring Harbor Perspectives in Biology
- Regulation of the Immune Response by TGF-β: From Conception to Autoimmunity and Infection
- (2017) Shomyseh Sanjabi et al. Cold Spring Harbor Perspectives in Biology
- TGF-β Family Signaling in Tumor Suppression and Cancer Progression
- (2017) Joan Seoane et al. Cold Spring Harbor Perspectives in Biology
- Targeting TGF-β Signaling for Therapeutic Gain
- (2017) Rosemary J. Akhurst Cold Spring Harbor Perspectives in Biology
- Simultaneous overactivation of Wnt/β-catenin and TGFβ signalling by miR-128-3p confers chemoresistance-associated metastasis in NSCLC
- (2017) Junchao Cai et al. Nature Communications
- TGF-β2-induced ANGPTL4 expression promotes tumor progression and osteoclast differentiation in giant cell tumor of bone
- (2017) Bo Li et al. Oncotarget
- The inhibition of cordycepin on cancer stemness in TGF-beta induced chemo-resistant ovarian cancer cell
- (2017) Chia-Woei Wang et al. Oncotarget
- TGFBR-IDH1-Cav1 axis promotes TGF-β signalling in cancer-associated fibroblast
- (2017) Xiaodan Hou et al. Oncotarget
- Tumor-fibroblast interactions stimulate tumor vascularization by enhancing cytokine-driven production of MMP9 by tumor cells
- (2017) Michelle Limoge et al. Oncotarget
- Transforming growth factor-β: A therapeutic target for cancer
- (2017) Sulsal Haque et al. Human Vaccines & Immunotherapeutics
- Stromal Modulators of TGF-β in Cancer
- (2017) Brunella Costanza et al. Journal of Clinical Medicine
- Metabolic Cooperation and Competition in the Tumor Microenvironment: Implications for Therapy
- (2017) Seema Gupta et al. Frontiers in Oncology
- Cancer-associated fibroblasts in digestive tumors
- (2017) Lei Huang et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Cyclooxygenase-2 regulates TGFβ-induced cancer stemness in triple-negative breast cancer
- (2017) Jun Tian et al. Scientific Reports
- Transforming growth factor-beta increases breast cancer stem cell population partially through upregulating PMEPA1 expression
- (2016) Zhi Nie et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- Hexokinase 2 is a determinant of neuroblastoma metastasis
- (2016) Liat Edry Botzer et al. BRITISH JOURNAL OF CANCER
- Cardiac Fibrosis
- (2016) Joshua G. Travers et al. CIRCULATION RESEARCH
- T Regulatory Cell Biology in Health and Disease
- (2016) Fayhan J. Alroqi et al. CURRENT ALLERGY AND ASTHMA REPORTS
- TGFβ signaling directs serrated adenomas to the mesenchymal colorectal cancer subtype
- (2016) Evelyn Fessler et al. EMBO Molecular Medicine
- Phase II study of Vigil® DNA engineered immunotherapy as maintenance in advanced stage ovarian cancer
- (2016) Jonathan Oh et al. GYNECOLOGIC ONCOLOGY
- Activin/Smad2-induced Histone H3 Lys-27 Trimethylation (H3K27me3) Reduction Is Crucial to Initiate Mesendoderm Differentiation of Human Embryonic Stem Cells
- (2016) Lu Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Transcriptional Control by the SMADs
- (2016) Caroline S. Hill Cold Spring Harbor Perspectives in Biology
- Structural Biology and Evolution of the TGF-β Family
- (2016) Andrew P. Hinck et al. Cold Spring Harbor Perspectives in Biology
- Signaling Receptors for TGF-β Family Members
- (2016) Carl-Henrik Heldin et al. Cold Spring Harbor Perspectives in Biology
- TGF-β Signaling from Receptors to Smads
- (2016) Akiko Hata et al. Cold Spring Harbor Perspectives in Biology
- Non-Smad Signaling Pathways of the TGF-β Family
- (2016) Ying E. Zhang Cold Spring Harbor Perspectives in Biology
- The Discovery and Early Days of TGF-β: A Historical Perspective
- (2016) Harold L. Moses et al. Cold Spring Harbor Perspectives in Biology
- TGF-β Family Signaling in the Control of Cell Proliferation and Survival
- (2016) Yun Zhang et al. Cold Spring Harbor Perspectives in Biology
- Regulation of the Bioavailability of TGF-β and TGF-β-Related Proteins
- (2016) Ian B. Robertson et al. Cold Spring Harbor Perspectives in Biology
- TGF-β and the TGF-β Family: Context-Dependent Roles in Cell and Tissue Physiology
- (2016) Masato Morikawa et al. Cold Spring Harbor Perspectives in Biology
- Mutational activation of BRAF confers sensitivity to transforming growth factor beta inhibitors in human cancer cells
- (2016) Lindsay C. Spender et al. Oncotarget
- Identification of novel long non-coding RNAs deregulated in hepatocellular carcinoma using RNA-sequencing
- (2016) Davide Degli Esposti et al. Oncotarget
- Genetic, epigenetic, and molecular landscapes of multifocal and multicentric glioblastoma
- (2015) Qun Liu et al. ACTA NEUROPATHOLOGICA
- Intratumoral Heterogeneity in EGFR-Mutant NSCLC Results in Divergent Resistance Mechanisms in Response to EGFR Tyrosine Kinase Inhibition
- (2015) M. Soucheray et al. CANCER RESEARCH
- Role of secreted modular calcium-binding protein 1 (SMOC1) in transforming growth factor β signalling and angiogenesis
- (2015) Khader Awwad et al. CARDIOVASCULAR RESEARCH
- TGF-β Promotes Heterogeneity and Drug Resistance in Squamous Cell Carcinoma
- (2015) Naoki Oshimori et al. CELL
- A phase III study of belagenpumatucel-L, an allogeneic tumour cell vaccine, as maintenance therapy for non-small cell lung cancer
- (2015) G. Giaccone et al. EUROPEAN JOURNAL OF CANCER
- Microbiota regulate the ability of lung dendritic cells to induce IgA class-switch recombination and generate protective gastrointestinal immune responses
- (2015) Darren Ruane et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The BRAFV600E inhibitor, PLX4032, increases type I collagen synthesis in melanoma cells
- (2015) Molly H. Jenkins et al. MATRIX BIOLOGY
- Transforming Growth Factor Beta Family: Insight into the Role of Growth Factors in Regulation of Fracture Healing Biology and Potential Clinical Applications
- (2015) Łukasz A. Poniatowski et al. MEDIATORS OF INFLAMMATION
- MicroRNAs, TGF-β signaling, and the inflammatory microenvironment in cancer
- (2015) Lingling Guo et al. TUMOR BIOLOGY
- CCL18 from tumor-associated macrophages promotes angiogenesis in breast cancer
- (2015) Ling Lin et al. Oncotarget
- Context-Specific Effects of TGF-β/SMAD3 in Cancer Are Modulated by the Epigenome
- (2015) Ana Tufegdzic Vidakovic et al. Cell Reports
- Metabolic Reprogramming of Cancer-Associated Fibroblasts by IDH3α Downregulation
- (2015) Daoxiang Zhang et al. Cell Reports
- Reciprocal regulation of TGF-β and reactive oxygen species: A perverse cycle for fibrosis
- (2015) Rui-Ming Liu et al. Redox Biology
- The Role of Mechanical Forces in Tumor Growth and Therapy
- (2014) Rakesh K. Jain et al. Annual Review of Biomedical Engineering
- Tumor-associated macrophages promote cancer stem cell-like properties via transforming growth factor-beta1-induced epithelial–mesenchymal transition in hepatocellular carcinoma
- (2014) Qing-Min Fan et al. CANCER LETTERS
- ALCAM/CD166 Is a TGF- -Responsive Marker and Functional Regulator of Prostate Cancer Metastasis to Bone
- (2014) A. G. Hansen et al. CANCER RESEARCH
- Id-1, a Protein Repressed by miR-29b, Facilitates the TGF�1-Induced Epithelial-Mesenchymal Transition in Human Ovarian Cancer Cells
- (2014) Yue Teng et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Hexokinase 2 regulates G1/S checkpoint through CDK2 in cancer-associated fibroblasts
- (2014) Jun-wei Hu et al. CELLULAR SIGNALLING
- Enhanced Bioactive Myocardial Transforming Growth Factor-β in Advanced Human Heart Failure
- (2014) Shaukat Khan et al. CIRCULATION JOURNAL
- TGF-β induces global changes in DNA methylation during the epithelial-to-mesenchymal transition in ovarian cancer cells
- (2014) Horacio Cardenas et al. Epigenetics
- Methylation of thePMEPA1gene, a negative regulator of the androgen receptor in prostate cancer
- (2014) Shashwat Sharad et al. Epigenetics
- Excessive Hyaluronan Production Promotes Acquisition of Cancer Stem Cell Signatures through the Coordinated Regulation of Twist and the Transforming Growth Factor β (TGF-β)-Snail Signaling Axis
- (2014) Theerawut Chanmee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Central role of Snail1 in the regulation of EMT and resistance in cancer: a target for therapeutic intervention
- (2014) Samantha Kaufhold et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Potent Anti-Inflammatory and Neuroprotective Effects of TGF- 1 Are Mediated through the Inhibition of ERK and p47phox-Ser345 Phosphorylation and Translocation in Microglia
- (2014) L. Qian et al. JOURNAL OF IMMUNOLOGY
- Conversion of Th17 into IL-17AnegRegulatory T Cells: A Novel Mechanism in Prolonged Allograft Survival Promoted by Mesenchymal Stem Cell–Supported Minimized Immunosuppressive Therapy
- (2014) Nataša Obermajer et al. JOURNAL OF IMMUNOLOGY
- Discovery of N-((4-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl)-2-fluoroaniline (EW-7197): A Highly Potent, Selective, and Orally Bioavailable Inhibitor of TGF-β Type I Receptor Kinase as Cancer Immunotherapeutic/Antifibrotic Agent
- (2014) Cheng Hua Jin et al. JOURNAL OF MEDICINAL CHEMISTRY
- The Role of TGF-β2 and Bone Morphogenetic Proteins in the Trabecular Meshwork and Glaucoma
- (2014) Robert J. Wordinger et al. JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS
- miR-106b modulates cancer stem cell characteristics through TGF-β/Smad signaling in CD44-positive gastric cancer cells
- (2014) Dayeon Yu et al. LABORATORY INVESTIGATION
- Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma
- (2014) Chong Sun et al. NATURE
- Molecular mechanisms of epithelial–mesenchymal transition
- (2014) Samy Lamouille et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Transforming growth factor β—at the centre of systemic sclerosis
- (2014) Robert Lafyatis Nature Reviews Rheumatology
- Phase I Study of GC1008 (Fresolimumab): A Human Anti-Transforming Growth Factor-Beta (TGFβ) Monoclonal Antibody in Patients with Advanced Malignant Melanoma or Renal Cell Carcinoma
- (2014) John C. Morris et al. PLoS One
- The Repressive Effect of miR-148a on TGF beta-SMADs Signal Pathway Is Involved in the Glabridin-Induced Inhibition of the Cancer Stem Cells-Like Properties in Hepatocellular Carcinoma Cells
- (2014) Fei Jiang et al. PLoS One
- Role of pyruvate kinase M2 in transcriptional regulation leading to epithelial-mesenchymal transition
- (2014) A. Hamabe et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Selective Targeting of TGF- Activation to Treat Fibroinflammatory Airway Disease
- (2014) S. Minagawa et al. Science Translational Medicine
- Reversal of Persistent Fibrosis in Aging by Targeting Nox4-Nrf2 Redox Imbalance
- (2014) L. Hecker et al. Science Translational Medicine
- Fibroblasts in fibrosis: novel roles and mediators
- (2014) Ryan T. Kendall et al. Frontiers in Pharmacology
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- (2013) Da Yang et al. CANCER CELL
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- (2013) Matthew T Blahna et al. CURRENT OPINION IN CELL BIOLOGY
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- (2013) Lior H Katz et al. EXPERT OPINION ON THERAPEUTIC TARGETS
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- (2013) Tsuyoshi Hasegawa et al. INTERNATIONAL JOURNAL OF CANCER
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- (2013) Bradford E. Hall et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TGF- : Guardian of T Cell Function
- (2013) S. A. Oh et al. JOURNAL OF IMMUNOLOGY
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- (2013) Rafael Kramann et al. JOURNAL OF PATHOLOGY
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- (2013) Keiji Hirota et al. NATURE IMMUNOLOGY
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- (2013) A Shukla et al. ONCOGENE
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- (2013) S. L. Friedman et al. Science Translational Medicine
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- (2013) Anna Śledzińska et al. PLOS BIOLOGY
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- (2012) Angelika Horn et al. ARTHRITIS AND RHEUMATISM
- Serotonin paracrine signaling in tissue fibrosis
- (2012) Derek A. Mann et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
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- (2012) Alexandre Calon et al. CANCER CELL
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- (2012) P. Juarez et al. CANCER RESEARCH
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- (2012) Sung-Jun Park et al. CELL
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- (2012) Makiko Fujii et al. CELL CYCLE
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- (2012) Claudia Capparelli et al. CELL CYCLE
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- (2012) Carmela Guido et al. CELL CYCLE
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- (2012) Rishi Vishal Luckheeram et al. Clinical & Developmental Immunology
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- (2012) Sebastian F. Schoppmann et al. CLINICAL & EXPERIMENTAL METASTASIS
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- (2012) Yoko Katsuno et al. CURRENT OPINION IN ONCOLOGY
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- (2012) Rui-Ming Liu et al. FREE RADICAL BIOLOGY AND MEDICINE
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- (2012) Yi-Lei Deng et al. Hepatobiliary & Pancreatic Diseases International
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- (2012) Erin C. Connolly et al. International Journal of Biological Sciences
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- (2012) Laurens A. van Meeteren et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2012) M. J. McGeachy et al. JOURNAL OF IMMUNOLOGY
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- (2012) Franco Klingberg et al. JOURNAL OF PATHOLOGY
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- (2012) Lenka Kubiczkova et al. Journal of Translational Medicine
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- (2012) Gobi Thillainadesan et al. MOLECULAR CELL
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- (2012) M Morikawa et al. ONCOGENE
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- (2012) Teresa A. Brentnall et al. PLoS One
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- (2012) Nicole Strong et al. PROSTATE
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- (2012) MITSUO SATO et al. RESPIROLOGY
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- (2012) Lei Jiang WORLD JOURNAL OF GASTROENTEROLOGY
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- (2012) Fei Huang et al. Cell and Bioscience
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- (2011) Ulrich Hofmann et al. AMERICAN JOURNAL OF PATHOLOGY
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- (2011) Federica Sotgia et al. Annual Review of Pathology-Mechanisms of Disease
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- (2011) Zhaodong Li et al. ARTHRITIS AND RHEUMATISM
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- (2011) Damian Medici et al. BIOCHEMICAL JOURNAL
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- (2011) Xiaohua Yan et al. BIOCHEMICAL JOURNAL
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- (2011) Jayashree P. Joshi et al. BIOCHEMICAL PHARMACOLOGY
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- (2011) Xinhai Wan et al. BONE
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- (2011) Paolo Cirri et al. CANCER AND METASTASIS REVIEWS
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- (2011) M. K. Asiedu et al. CANCER RESEARCH
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- (2011) Karl-Hermann Schlingensiepen et al. CANCER SCIENCE
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- (2011) Alan C. Mullen et al. CELL
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- (2011) Christina Scheel et al. CELL
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- (2011) Stephanos Pavlides et al. CELL CYCLE
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- (2011) Frank Jaschinski et al. CURRENT PHARMACEUTICAL BIOTECHNOLOGY
- Erratum
- (2011) &NA; DRUGS
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- (2011) Reena Rani et al. EUROPEAN JOURNAL OF IMMUNOLOGY
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- (2011) MOLLY A. TAYLOR et al. GENE EXPRESSION
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- (2011) Anna Biernacka et al. GROWTH FACTORS
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- (2011) Ubaldo E. Martinez-Outschoorn et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
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- (2011) A. Safina et al. MOLECULAR CANCER RESEARCH
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- (2011) Andrea Facciabene et al. NATURE
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- (2011) Eric A Collisson et al. NATURE MEDICINE
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- (2011) P-K Lo et al. ONCOGENE
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- (2011) M-T Lau et al. ONCOGENE
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- (2011) Hildegonda P. H. Naber et al. CELLULAR ONCOLOGY
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- (2010) Jinfang Zhu et al. Annual Review of Immunology
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- (2010) Jean-Philippe Coppé et al. Annual Review of Pathology-Mechanisms of Disease
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- (2010) Anne S. Dejean et al. ANTIOXIDANTS & REDOX SIGNALING
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- (2010) Y Wu et al. BRITISH JOURNAL OF CANCER
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- (2010) P. Papageorgis et al. CANCER RESEARCH
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- (2010) K. S. Mohammad et al. CANCER RESEARCH
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- (2010) Ubaldo E. Martinez-Outschoorn et al. CELL CYCLE
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- (2010) Ubaldo E. Martinez-Outschoorn et al. CELL CYCLE
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- (2010) S P Cullen et al. CELL DEATH AND DIFFERENTIATION
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- (2010) Steffen K. Meurer et al. CELLULAR SIGNALLING
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- (2010) N. Akizu et al. DEVELOPMENT
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- (2010) Coert Margadant et al. EMBO REPORTS
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- (2010) Martin Kohan et al. FASEB JOURNAL
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- (2010) Kazuhito Naka et al. NATURE
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- (2010) U. Bogdahn et al. NEURO-ONCOLOGY
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- (2010) S Ehata et al. ONCOGENE
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- (2010) O. Dahle et al. Science Signaling
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- (2010) M. Konigshoff et al. THORAX
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- (2010) Li Yang et al. TRENDS IN IMMUNOLOGY
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- (2010) Marion Peyrou WORLD JOURNAL OF GASTROENTEROLOGY
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- (2009) Guofei Zhou et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
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- (2009) Mei Rosa Ng et al. CANCER CELL
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- (2009) Silvia Peñuelas et al. CANCER CELL
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- (2009) Bixiang Zhang et al. CANCER LETTERS
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- (2009) Sirio Dupont et al. CELL
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- (2009) Kandice R. Levental et al. CELL
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- (2009) Jian Xu et al. CELL RESEARCH
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- (2009) Hiroaki Ikushima et al. Cell Stem Cell
- Autocrine TGF-β Signaling Maintains Tumorigenicity of Glioma-Initiating Cells through Sry-Related HMG-Box Factors
- (2009) Hiroaki Ikushima et al. Cell Stem Cell
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- (2009) Carl-Henrik Heldin et al. CURRENT OPINION IN CELL BIOLOGY
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- (2009) Shomyseh Sanjabi et al. CURRENT OPINION IN PHARMACOLOGY
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- (2009) Brian Bierie et al. CYTOKINE & GROWTH FACTOR REVIEWS
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- (2009) Nagathihalli S Nagaraj et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
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- (2009) Yeonseok Chung et al. IMMUNITY
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- (2009) YangXin Fu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2009) Raghu Kalluri et al. JOURNAL OF CLINICAL INVESTIGATION
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- (2009) Ronan J. Kelly et al. Journal of Immunotoxicology
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- (2008) Peter ten Dijke et al. ANGIOGENESIS
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- (2008) Li Yang et al. CANCER CELL
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- (2008) J.-S. Nam et al. CANCER RESEARCH
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- (2008) L. Yang et al. CANCER RESEARCH
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- (2008) Ming O. Li et al. CELL
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- (2008) David Padua et al. CELL
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- (2008) Joan Massagué CELL
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- (2008) David Padua et al. CELL RESEARCH
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- (2008) Xing Guo et al. CELL RESEARCH
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- (2008) Ying E Zhang CELL RESEARCH
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- (2008) Laura A. Tesmer et al. IMMUNOLOGICAL REVIEWS
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- (2008) Harsha Dadlani et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2008) Kana Horiguchi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2008) D. Melisi et al. MOLECULAR CANCER THERAPEUTICS
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- (2008) Motozo Yamashita et al. MOLECULAR CELL
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- (2008) Liang Zhou et al. NATURE
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- (2008) Alessandro Sorrentino et al. NATURE CELL BIOLOGY
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- (2008) Terrence Town et al. NATURE MEDICINE
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- (2008) B. Schmierer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulatory T Cells: Mechanisms of Differentiation and Function
- (2007) Steven Z. Josefowicz et al. Annual Review of Immunology
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- (2007) TA Wynn JOURNAL OF PATHOLOGY
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