Organ Fibrosis and Autoimmunity: The Role of Inflammation in TGFβ-Dependent EMT
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Title
Organ Fibrosis and Autoimmunity: The Role of Inflammation in TGFβ-Dependent EMT
Authors
Keywords
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Journal
Biomolecules
Volume 11, Issue 2, Pages 310
Publisher
MDPI AG
Online
2021-02-19
DOI
10.3390/biom11020310
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Note: Only part of the references are listed.- TGFβ1-Smad canonical and -Erk noncanonical pathways participate in interleukin-17-induced epithelial–mesenchymal transition in Sjögren’s syndrome
- (2020) Margherita Sisto et al. LABORATORY INVESTIGATION
- Transforming Growth Factor-Beta1 in Diabetic Kidney Disease
- (2020) Lijun Zhao et al. Frontiers in Cell and Developmental Biology
- IL-6 Contributes to the TGF-β1-Mediated Epithelial to Mesenchymal Transition in Human Salivary Gland Epithelial Cells
- (2020) Margherita Sisto et al. ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS
- Inflammation-induced endothelial to mesenchymal transition promotes brain endothelial cell dysfunction and occurs during multiple sclerosis pathophysiology
- (2019) Claudio Derada Troletti et al. Cell Death & Disease
- Therapeutic Targeting of Fibrotic Epithelial-Mesenchymal Transition–An Outstanding Challenge
- (2019) Attila Fintha et al. Frontiers in Pharmacology
- Interleukin‐17 and Interleukin‐22 synergy linking inflammation and EMT ‐ dependent fibrosis in Sjögren's syndrome
- (2019) Margherita Sisto et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Transforming growth factor β1 promotes fibroblast-like synoviocytes migration and invasion via TGF-β1/Smad signaling in rheumatoid arthritis
- (2019) DingJi Zhu et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Regulation of Immune Responses and Chronic Inflammation by Fibroblast-Like Synoviocytes
- (2019) Hiroyuki Yoshitomi Frontiers in Immunology
- Pirfenidone ameliorates lipopolysaccharide-induced pulmonary inflammation and fibrosis by blocking NLRP3 inflammasome activation
- (2018) Yi Li et al. MOLECULAR IMMUNOLOGY
- Primary Sjögren’s Syndrome
- (2018) Xavier Mariette et al. NEW ENGLAND JOURNAL OF MEDICINE
- Diabetes induces fibrotic changes in the lung through the activation of TGF-β signaling pathways
- (2018) Girish Talakatta et al. Scientific Reports
- Transforming Growth Factor-β-Induced Cell Plasticity in Liver Fibrosis and Hepatocarcinogenesis
- (2018) Isabel Fabregat et al. Frontiers in Oncology
- The TGF-β1 Signaling Pathway as an Attractive Target in the Fibrosis Pathogenesis of Sjögren’s Syndrome
- (2018) Margherita Sisto et al. MEDIATORS OF INFLAMMATION
- Loss of Smad7 Promotes Inflammation in Rheumatoid Arthritis
- (2018) Gengmin Zhou et al. Frontiers in Immunology
- Epithelial–mesenchymal transition in Crohn’s disease
- (2017) H Jiang et al. Mucosal Immunology
- Cell plasticity in epithelial homeostasis and tumorigenesis
- (2017) Julia Varga et al. NATURE CELL BIOLOGY
- TGF-β1 Signaling and Tissue Fibrosis
- (2017) Kevin K. Kim et al. Cold Spring Harbor Perspectives in Biology
- The molecular basis of endothelial cell plasticity
- (2017) Elisabetta Dejana et al. Nature Communications
- Snail Is a Critical Mediator of Invadosome Formation and Joint Degradation in Arthritis
- (2016) Annie Lauzier et al. AMERICAN JOURNAL OF PATHOLOGY
- Molecular alterations of the blood–brain barrier under inflammatory conditions: The role of endothelial to mesenchymal transition
- (2016) Claudio Derada Troletti et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Cardiac Fibrosis
- (2016) Joshua G. Travers et al. CIRCULATION RESEARCH
- Amplified canonical transforming growth factor-β signallingviaheat shock protein 90 in pulmonary fibrosis
- (2016) Zaneta Sibinska et al. EUROPEAN RESPIRATORY JOURNAL
- TGF-β signalling and liver disease
- (2016) Isabel Fabregat et al. FEBS Journal
- TGF-β/SMAD Pathway and Its Regulation in Hepatic Fibrosis
- (2016) Fengyun Xu et al. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
- TGF-β: the master regulator of fibrosis
- (2016) Xiao-ming Meng et al. Nature Reviews Nephrology
- Transcriptional Control by the SMADs
- (2016) Caroline S. Hill Cold Spring Harbor Perspectives in Biology
- Signaling Receptors for TGF-β Family Members
- (2016) Carl-Henrik Heldin et al. Cold Spring Harbor Perspectives in Biology
- Non-Smad Signaling Pathways of the TGF-β Family
- (2016) Ying E. Zhang Cold Spring Harbor Perspectives in Biology
- Regulation of TGF-β Family Signaling by Inhibitory Smads
- (2016) Keiji Miyazawa et al. Cold Spring Harbor Perspectives in Biology
- Mongersen, an oral Smad7 antisense oligonucleotide, in patients with active Crohn’s disease
- (2016) Sandro Ardizzone et al. Therapeutic Advances in Gastroenterology
- Pathological Roles of Interleukin-22 in the Development of Recurrent Hepatitis C after Liver Transplantation
- (2016) Yinjie Gao et al. PLoS One
- AJKD Atlas of Renal Pathology: Diabetic Nephropathy
- (2015) Behzad Najafian et al. AMERICAN JOURNAL OF KIDNEY DISEASES
- Epithelial-mesenchymal transition: An emerging target in tissue fibrosis
- (2015) Meirong Li et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Brain barriers: Crosstalk between complex tight junctions and adherens junctions
- (2015) Silvia Tietz et al. JOURNAL OF CELL BIOLOGY
- Bacterial induction of Snail1 contributes to blood-brain barrier disruption
- (2015) Brandon J. Kim et al. JOURNAL OF CLINICAL INVESTIGATION
- The Inflammatory Actions of Coagulant and Fibrinolytic Proteases in Disease
- (2015) Michael Schuliga MEDIATORS OF INFLAMMATION
- Bleomycin induced epithelial–mesenchymal transition (EMT) in pleural mesothelial cells
- (2015) Li-Jun Chen et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Increased Expression of TGF-β Signaling Components in a Mouse Model of Fibrosis Induced by Submandibular Gland Duct Ligation
- (2015) Lucas T. Woods et al. PLoS One
- Identification of a Cell-of-Origin for Fibroblasts Comprising the Fibrotic Reticulum in Idiopathic Pulmonary Fibrosis
- (2014) Hong Xia et al. AMERICAN JOURNAL OF PATHOLOGY
- Depletion of Thymosin �4 Promotes the Proliferation, Migration, and Activation of Human Hepatic Stellate Cells
- (2014) Yongtao Xiao et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Fibrotic extracellular matrix activates a profibrotic positive feedback loop
- (2014) Matthew W. Parker et al. JOURNAL OF CLINICAL INVESTIGATION
- Central role of Snail1 in the regulation of EMT and resistance in cancer: a target for therapeutic intervention
- (2014) Samantha Kaufhold et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Dual Roles of Immunoregulatory Cytokine TGF- in the Pathogenesis of Autoimmunity-Mediated Organ Damage
- (2014) V. Saxena et al. JOURNAL OF IMMUNOLOGY
- Curtailing Endothelial TGF- Signaling Is Sufficient to Reduce Endothelial-Mesenchymal Transition and Fibrosis in CKD
- (2014) S. Xavier et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Molecular mechanisms of epithelial–mesenchymal transition
- (2014) Samy Lamouille et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Transforming Growth Factor-Beta and Matrix Metalloproteinases: Functional Interactions in Tumor Stroma-Infiltrating Myeloid Cells
- (2014) Jelena Krstic et al. TheScientificWorldJOURNAL
- Evidence for and against epithelial-to-mesenchymal transition in the liver
- (2013) Guanhua Xie et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Chemokine receptor CCR6-dependent accumulation of γδ T cells in injured liver restricts hepatic inflammation and fibrosis
- (2013) Linda Hammerich et al. HEPATOLOGY
- Transforming Growth Factor-β1 (TGF-β1)-stimulated Fibroblast to Myofibroblast Differentiation Is Mediated by Hyaluronan (HA)-facilitated Epidermal Growth Factor Receptor (EGFR) and CD44 Co-localization in Lipid Rafts
- (2013) Adam C. Midgley et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Transforming Growth Factor-β (TGF-β)-mediated Connective Tissue Growth Factor (CTGF) Expression in Hepatic Stellate Cells Requires Stat3 Signaling Activation
- (2013) Yan Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Development, maintenance and disruption of the blood-brain barrier
- (2013) Birgit Obermeier et al. NATURE MEDICINE
- Blocking the Class I Histone Deacetylase Ameliorates Renal Fibrosis and Inhibits Renal Fibroblast Activation via Modulating TGF-Beta and EGFR Signaling
- (2013) Na Liu et al. PLoS One
- IL-22 contributes to TGF-β1-mediated epithelial-mesenchymal transition in asthmatic bronchial epithelial cells
- (2013) Jill R Johnson et al. RESPIRATORY RESEARCH
- Transforming Growth Factor β-1 Stimulates Profibrotic Epithelial Signaling to Activate Pericyte-Myofibroblast Transition in Obstructive Kidney Fibrosis
- (2012) Ching-Fang Wu et al. AMERICAN JOURNAL OF PATHOLOGY
- Rituximab modulates the expression of IL-22 in the salivary glands of patients with primary Sjogren's syndrome
- (2012) Francesco Ciccia et al. ANNALS OF THE RHEUMATIC DISEASES
- Inflammatory events at blood-brain barrier in neuroinflammatory and neurodegenerative disorders: Implications for clinical disease
- (2012) Helga E. de Vries et al. EPILEPSIA
- The genetics of multiple sclerosis: an up-to-date review
- (2012) Pierre-Antoine Gourraud et al. IMMUNOLOGICAL REVIEWS
- Mechanisms of fibrosis: therapeutic translation for fibrotic disease
- (2012) Thomas A Wynn et al. NATURE MEDICINE
- How Does TGF-β Mediate Tubulointerstitial Fibrosis?
- (2012) Leslie Gewin et al. SEMINARS IN NEPHROLOGY
- Differential Regulation of TGF-β/Smad Signaling in Hepatic Stellate Cells between Acute and Chronic Liver Injuries
- (2012) Katsunori Yoshida et al. Frontiers in Physiology
- Claudin-1 induced sealing of blood–brain barrier tight junctions ameliorates chronic experimental autoimmune encephalomyelitis
- (2011) Friederike Pfeiffer et al. ACTA NEUROPATHOLOGICA
- An Official ATS/ERS/JRS/ALAT Statement: Idiopathic Pulmonary Fibrosis: Evidence-based Guidelines for Diagnosis and Management
- (2011) Ganesh Raghu et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Potential involvement of IL-22 and IL-22-producing cells in the inflamed salivary glands of patients with Sjögren's syndrome
- (2011) Francesco Ciccia et al. ANNALS OF THE RHEUMATIC DISEASES
- The Ins and Outs of the Epithelial to Mesenchymal Transition in Health and Disease
- (2011) M. Angela Nieto Annual Review of Cell and Developmental Biology
- The role of EMT in renal fibrosis
- (2011) Rosemarie M. Carew et al. CELL AND TISSUE RESEARCH
- The role of TGF-β and epithelial-to mesenchymal transition in diabetic nephropathy
- (2011) Claire E. Hills et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Pulmonary fibrosis: a possible diabetic complication
- (2011) Junling Yang et al. DIABETES-METABOLISM RESEARCH AND REVIEWS
- TGF-β signaling in fibrosis
- (2011) Anna Biernacka et al. GROWTH FACTORS
- Role of Treg Cells and TGF-β1 in Patients with Systemic Lupus Erythematosus: A Possible Relation with Lupus Nephritis
- (2011) Qian Xing et al. IMMUNOLOGICAL INVESTIGATIONS
- Epithelial-mesenchymal transition in renal fibrosis - evidence for and against
- (2011) Maria Fragiadaki et al. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY
- Epithelial-mesenchymal transition (EMT) in kidney fibrosis: fact or fantasy?
- (2011) Wilhelm Kriz et al. JOURNAL OF CLINICAL INVESTIGATION
- Idiopathic pulmonary fibrosis
- (2011) Talmadge E King et al. LANCET
- Decreased serum levels of TGF-β1 are associated with renal damage in female patients with systemic lupus erythematosus
- (2011) T Jin et al. LUPUS
- Hepatocyte-Derived Snail1 Propagates Liver Fibrosis Progression
- (2011) R. G. Rowe et al. MOLECULAR AND CELLULAR BIOLOGY
- Blockade of Endothelial-Mesenchymal Transition by a Smad3 Inhibitor Delays the Early Development of Streptozotocin-Induced Diabetic Nephropathy
- (2010) J. Li et al. DIABETES
- Cellular and molecular basis for the regulation of inflammation by TGF-
- (2010) A. Yoshimura et al. JOURNAL OF BIOCHEMISTRY
- Identification of Epithelial to Mesenchymal Transition as a Novel Source of Fibroblasts in Intestinal Fibrosis
- (2010) Sarah N. Flier et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- IKK controls canonical TGF -SMAD signaling to regulate genes expressing SNAIL and SLUG during EMT in Panc1 cells
- (2010) M. Brandl et al. JOURNAL OF CELL SCIENCE
- Epithelium-specific deletion of TGF-β receptor type II protects mice from bleomycin-induced pulmonary fibrosis
- (2010) Min Li et al. JOURNAL OF CLINICAL INVESTIGATION
- Levels of Transforming Growth Factor- Are Low in Systemic Lupus Erythematosus Patients with Active Disease
- (2010) A. BECKER-MEROK et al. JOURNAL OF RHEUMATOLOGY
- Conditional overexpression of TGF-β1 disrupts mouse salivary gland development and function
- (2010) Bradford E Hall et al. LABORATORY INVESTIGATION
- Conversion of vascular endothelial cells into multipotent stem-like cells
- (2010) Damian Medici et al. NATURE MEDICINE
- The immunology of fibrosis: innate and adaptive responses
- (2010) Georg Wick et al. TRENDS IN IMMUNOLOGY
- Endothelial–Mesenchymal Transition as a Novel Mechanism for Generating Myofibroblasts during Diabetic Nephropathy
- (2009) Akane Kizu et al. AMERICAN JOURNAL OF PATHOLOGY
- Endothelial-Myofibroblast Transition Contributes to the Early Development of Diabetic Renal Interstitial Fibrosis in Streptozotocin-Induced Diabetic Mice
- (2009) Jinhua Li et al. AMERICAN JOURNAL OF PATHOLOGY
- Contribution of Epithelial-derived Fibroblasts to Bleomycin-induced Lung Fibrosis
- (2009) Harikrishna Tanjore et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- TGF-β and fibrosis in different organs — molecular pathway imprints
- (2009) Dirk Pohlers et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Epithelial-Mesenchymal Transitions in Development and Disease
- (2009) Jean Paul Thiery et al. CELL
- Patients Diagnosed With Diabetes Are at Increased Risk for Asthma, Chronic Obstructive Pulmonary Disease, Pulmonary Fibrosis, and Pneumonia but Not Lung Cancer
- (2009) S. F. Ehrlich et al. DIABETES CARE
- Inflammation and EMT: an alliance towards organ fibrosis and cancer progression
- (2009) Jose Miguel López-Novoa et al. EMBO Molecular Medicine
- Mechanisms of the epithelial–mesenchymal transition by TGF-β
- (2009) Michael K Wendt et al. Future Oncology
- Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease
- (2009) Hervé Acloque et al. JOURNAL OF CLINICAL INVESTIGATION
- EMT: When epithelial cells decide to become mesenchymal-like cells
- (2009) Raghu Kalluri JOURNAL OF CLINICAL INVESTIGATION
- Biomarkers for epithelial-mesenchymal transitions
- (2009) Michael Zeisberg et al. JOURNAL OF CLINICAL INVESTIGATION
- The basics of epithelial-mesenchymal transition
- (2009) Raghu Kalluri et al. JOURNAL OF CLINICAL INVESTIGATION
- HGF and BMP-7 Ameliorate High Glucose-Induced Epithelial-to-Mesenchymal Transition of Peritoneal Mesothelium
- (2009) M.-A Yu et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- New Insights into Epithelial-Mesenchymal Transition in Kidney Fibrosis
- (2009) Y. Liu JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Expression of TGFβ1 and Its Signaling Components by Peripheral Lymphocytes in Systemic Lupus Erythematosus
- (2009) Eszter Kohut et al. PATHOLOGY & ONCOLOGY RESEARCH
- The role of endothelial-to-mesenchymal transition in cancer progression
- (2008) S Potenta et al. BRITISH JOURNAL OF CANCER
- Phospho-control of TGF-β superfamily signaling
- (2008) Katharine H Wrighton et al. CELL RESEARCH
- Non-Smad pathways in TGF-β signaling
- (2008) Ying E Zhang CELL RESEARCH
- Brain Endothelial Cell-Cell Junctions: How to “Open” the Blood Brain Barrier
- (2008) Svetlana Stamatovic et al. Current Neuropharmacology
- Epithelial-Mesenchymal Transition: At the Crossroads of Development and Tumor Metastasis
- (2008) Jing Yang et al. DEVELOPMENTAL CELL
- Fibroblasts emerge via epithelial-mesenchymal transition in chronic kidney fibrosis
- (2008) Michael Zeisberg Frontiers in Bioscience-Landmark
- Hepatocyte-Specific Smad7 Expression Attenuates TGF-β–Mediated Fibrogenesis and Protects Against Liver Damage
- (2008) Steven Dooley et al. GASTROENTEROLOGY
- Keratinocyte-specific Smad2 ablation results in increased epithelial-mesenchymal transition during skin cancer formation and progression
- (2008) Kristina E. Hoot et al. JOURNAL OF CLINICAL INVESTIGATION
- Fibroblasts in Kidney Fibrosis Emerge via Endothelial-to-Mesenchymal Transition
- (2008) E. M. Zeisberg et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- EMT and proteinuria as progression factors
- (2008) Frank M. Strutz KIDNEY INTERNATIONAL
- Fibrotic Myofibroblasts Manifest Genome-Wide Derangements of Translational Control
- (2008) Ola Larsson et al. PLoS One
- Cellular and molecular mechanisms of fibrosis
- (2007) TA Wynn JOURNAL OF PATHOLOGY
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