Smad7: not only a regulator, but also a cross-talk mediator of TGF-β signalling

Smad7 and Smad6 bind to discrete regions of Pellino-1 via their MH2 domains to mediate TGF-β1-induced negative regulation of IL-1R/TLR signaling

(2010) Youn Sook Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Murine Protein Serine/Threonine Kinase 38 Stimulates TGF-β Signaling in a Kinase-dependent Manner via Direct Phosphorylation of Smad Proteins

(2010) Hyun-A Seong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Smad7 Inhibits Transforming Growth Factor-β Family Type I Receptors through Two Distinct Modes of Interaction

(2010) Yuto Kamiya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Smad7 restricts melanoma invasion by restoring N-cadherin expression and establishing heterotypic cell-cell interactions in vivo

(2010) Kyle A. DiVito et al.   Pigment Cell & Melanoma Research

In Vivo Disruption of TGF-β Signaling by Smad7 in Airway Epithelium Alleviates Allergic Asthma but Aggravates Lung Carcinogenesis in Mouse

(2010) Xiaolin Luo et al.   PLoS One

TGF-β and immune cells: an important regulatory axis in the tumor microenvironment and progression

(2010) Li Yang et al.   TRENDS IN IMMUNOLOGY

Regulation of TGF-  signaling by Smad7

(2009) X. Yan et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Nuclear β-Catenin Induces an Early Liver Progenitor Phenotype in Hepatocellular Carcinoma and Promotes Tumor Recurrence

(2009) Gudrun Zulehner et al.   AMERICAN JOURNAL OF PATHOLOGY

Increased IκBα expression is essential for the tolerogenic property of TGF-β-exposed APCs

(2009) Paiman Ghafoori et al.   FASEB JOURNAL

Mechanisms of the epithelial–mesenchymal transition by TGF-β

(2009) Michael K Wendt et al.   Future Oncology

Interleukin-23/Th17 pathways and inflammatory bowel disease

(2009) Clara Abraham et al.   INFLAMMATORY BOWEL DISEASES

Human BAMBI Cooperates with Smad7 to Inhibit Transforming Growth Factor-β Signaling

(2009) Xiaohua Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Foxp3+ Regulatory T Cells, Th17 Effector Cells, and Cytokine Environment in Inflammatory Bowel Disease

(2009) Nicola Eastaff-Leung et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Nuclear Function of Smad7 Promotes Myogenesis

(2009) T. Miyake et al.   MOLECULAR AND CELLULAR BIOLOGY

New regulatory mechanisms of TGF-β receptor function

(2009) Jong Seok Kang et al.   TRENDS IN CELL BIOLOGY

Study of interaction between Smad7 and DNA by single-molecule force spectroscopy

(2008) Xiaoli Shi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Smad7 induces hepatic metastasis in colorectal cancer

(2008) S K Halder et al.   BRITISH JOURNAL OF CANCER

TGF-β: A Master of All T Cell Trades

(2008) Ming O. Li et al.   CELL

TGFβ in Cancer

(2008) Joan Massagué   CELL

Regulating the stability of TGFβ receptors and Smads

(2008) Peter Lönn et al.   CELL RESEARCH

Signaling cross-talk between TGF-β/BMP and other pathways

(2008) Xing Guo et al.   CELL RESEARCH

Non-Smad pathways in TGF-β signaling

(2008) Ying E Zhang   CELL RESEARCH

Smad7 Stabilizes β-Catenin Binding to E-cadherin Complex and Promotes Cell-Cell Adhesion

(2008) Yi Tang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Smad7 Is Required for the Development and Function of the Heart

(2008) Qian Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Smad7 Inhibits Chondrocyte Differentiation at Multiple Steps during Endochondral Bone Formation and Down-regulates p38 MAPK Pathways

(2008) Takao Iwai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TGFβ induces SIK to negatively regulate type I receptor kinase signaling

(2008) Marcin Kowanetz et al.   JOURNAL OF CELL BIOLOGY

Tieg3/Klf11 induces apoptosis in OLI-neu cells and enhances the TGF-β signaling pathway by transcriptional repression of Smad7

(2008) Gabriele Gohla et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Inflammatory bowel disease, past, present and future: lessons from animal models

(2008) Atsushi Mizoguchi et al.   JOURNAL OF GASTROENTEROLOGY

Specific Activation of Mitogen-activated Protein Kinase by Transforming Growth Factor-β Receptors in Lipid Rafts Is Required for Epithelial Cell Plasticity

(2008) Wei Zuo et al.   MOLECULAR BIOLOGY OF THE CELL

TRAF6 Mediates Smad-Independent Activation of JNK and p38 by TGF-β

(2008) Motozo Yamashita et al.   MOLECULAR CELL

The type I TGF-β receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner

(2008) Alessandro Sorrentino et al.   NATURE CELL BIOLOGY

Smad7 is inactivated through a direct physical interaction with the LIM protein Hic-5/ARA55

(2008) H Wang et al.   ONCOGENE

Critical regulation of TGF  signaling by Hsp90

(2008) K. H. Wrighton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TGF-β1 is increased in a transgenic mouse model of familial Alzheimer's disease and causes neuronal apoptosis

(2007) Pradeep Salins et al.   NEUROSCIENCE LETTERS