Long noncoding RNA H19X is a key mediator of TGF-β–driven fibrosis

lncRNA MIR503HG functioned as a tumor suppressor and inhibited cell proliferation, metastasis and epithelial-mesenchymal transition in bladder cancer

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Functional Classification and Experimental Dissection of Long Noncoding RNAs

(2018) Florian Kopp et al.   CELL

Long noncoding RNA miR503HG, a prognostic indicator, inhibits tumor metastasis by regulating the HNRNPA2B1/NF-κB pathway in hepatocellular carcinoma

(2018) Hui Wang et al.   Theranostics

TGF-β Signaling in Lung Health and Disease

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Novel players in X inactivation: insights into Xist-mediated gene silencing and chromosome conformation

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DDiT4L promotes autophagy and inhibits pathological cardiac hypertrophy in response to stress

(2017) Bridget Simonson et al.   Science Signaling

Targeted apoptosis of myofibroblasts with the BH3 mimetic ABT-263 reverses established fibrosis

(2017) David Lagares et al.   Science Translational Medicine

GeneHancer: genome-wide integration of enhancers and target genes in GeneCards

(2017) Simon Fishilevich et al.   Database-The Journal of Biological Databases and Curation

Novel players in X inactivation: insights into Xist-mediated gene silencing and chromosome conformation

(2017) Simão T da Rocha et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DDiT4L promotes autophagy and inhibits pathological cardiac hypertrophy in response to stress

(2017) Bridget Simonson et al.   Science Signaling

TGF-β signalling and liver disease

(2016) Isabel Fabregat et al.   FEBS Journal

TGF-β: the master regulator of fibrosis

(2016) Xiao-ming Meng et al.   Nature Reviews Nephrology

Transforming growth factor beta (TGF-β) isoforms in wound healing and fibrosis

(2016) Michael K. Lichtman et al.   WOUND REPAIR AND REGENERATION

Long non-coding RNA-H19 antagonism protects against renal fibrosis

(2016) Hong Xie et al.   Oncotarget

Development of Long Noncoding RNA-Based Strategies to Modulate Tissue Vascularization

(2015) Jan Fiedler et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Orphan nuclear receptor NR4A1 regulates transforming growth factor-β signaling and fibrosis

(2015) Katrin Palumbo-Zerr et al.   NATURE MEDICINE

MEG3 long noncoding RNA regulates the TGF-β pathway genes through formation of RNA–DNA triplex structures

(2015) Tanmoy Mondal et al.   Nature Communications

Dissecting the Heterogeneity of Skin Gene Expression Patterns in Systemic Sclerosis

(2015) Shervin Assassi et al.   Arthritis & Rheumatology

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(2015) Yannick Allanore et al.   Nature Reviews Disease Primers

Inhibitory effects of long noncoding RNA MEG3 on hepatic stellate cells activation and liver fibrogenesis

(2014) Yong He et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping

(2014) Suhas S.P. Rao et al.   CELL

The Noncoding RNA Revolution—Trashing Old Rules to Forge New Ones

(2014) Thomas R. Cech et al.   CELL

REDD2-mediated inhibition of mTOR promotes dendrite retraction induced by axonal injury

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(2014) Mandana Nikpour et al.   CURRENT OPINION IN RHEUMATOLOGY

The evolution of lncRNA repertoires and expression patterns in tetrapods

(2014) Anamaria Necsulea et al.   NATURE

Transforming growth factor β—at the centre of systemic sclerosis

(2014) Robert Lafyatis   Nature Reviews Rheumatology

Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre

(2014) Ezgi Hacisuleyman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Identification of a radiation sensitivity gene expression profile in primary fibroblasts derived from patients who developed radiotherapy-induced fibrosis

(2014) Helen B. Forrester et al.   RADIOTHERAPY AND ONCOLOGY

Narrative Review: Fibrotic Diseases: Cellular and Molecular Mechanisms and Novel Therapies

(2013) Joel Rosenbloom   ANNALS OF INTERNAL MEDICINE

2013 classification criteria for systemic sclerosis: an American college of rheumatology/European league against rheumatism collaborative initiative

(2013) Frank van den Hoogen et al.   ANNALS OF THE RHEUMATIC DISEASES

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(2013) Paul Flicek et al.   NUCLEIC ACIDS RESEARCH

Multiple knockout mouse models reveal lincRNAs are required for life and brain development

(2013) Martin Sauvageau et al.   eLife

Association of Interferon- and Transforming Growth Factor β-Regulated Genes and Macrophage Activation With Systemic Sclerosis-Related Progressive Lung Fibrosis

(2013) Romy B. Christmann et al.   Arthritis & Rheumatology

Regulation of mammalian cell differentiation by long non-coding RNAs

(2012) Wenqian Hu et al.   EMBO REPORTS

An integrated encyclopedia of DNA elements in the human genome

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The H19 lincRNA is a developmental reservoir of miR-675 that suppresses growth and Igf1r

(2012) Andrew Keniry et al.   NATURE CELL BIOLOGY

Transcription factor and chromatin features predict genes associated with eQTLs

(2012) Dennis Wang et al.   NUCLEIC ACIDS RESEARCH

Chromatin Isolation by RNA Purification (ChIRP)

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Canonical Wnt signaling induces skin fibrosis and subcutaneous lipoatrophy: A novel mouse model for scleroderma?

(2011) Jun Wei et al.   ARTHRITIS AND RHEUMATISM

Genomic Maps of Long Noncoding RNA Occupancy Reveal Principles of RNA-Chromatin Interactions

(2011) Ci Chu et al.   MOLECULAR CELL

Lung tissues in patients with systemic sclerosis have gene expression patterns unique to pulmonary fibrosis and pulmonary hypertension

(2010) Eileen Hsu et al.   ARTHRITIS AND RHEUMATISM

Transforming growth factor β as a therapeutic target in systemic sclerosis

(2009) John Varga et al.   Nature Reviews Rheumatology