Casein Kinase 1δ/ε Inhibitor, PF670462 Attenuates the Fibrogenic Effects of Transforming Growth Factor-β in Pulmonary Fibrosis

Safer approaches to therapeutic modulation of TGF-β signaling for respiratory disease

(2018) Philippe Lachapelle et al.   PHARMACOLOGY & THERAPEUTICS

Emerging therapies for idiopathic pulmonary fibrosis, a progressive age-related disease

(2017) Ana L. Mora et al.   NATURE REVIEWS DRUG DISCOVERY

Glucocorticoid Insensitivity in Virally Infected Airway Epithelial Cells Is Dependent on Transforming Growth Factor-β Activity

(2017) Yuxiu C. Xia et al.   PLoS Pathogens

Pirfenidone Initiates a New Era in the Treatment of Idiopathic Pulmonary Fibrosis

(2016) Anna S. Selvaggio et al.   Annual Review of Medicine

Translational models of lung disease

(2015) Paul F. Mercer et al.   CLINICAL SCIENCE

Mode of action of nintedanib in the treatment of idiopathic pulmonary fibrosis

(2015) Lutz Wollin et al.   EUROPEAN RESPIRATORY JOURNAL

Casein Kinase 1δ/ε Inhibitor PF-5006739 Attenuates Opioid Drug-Seeking Behavior

(2014) Travis T. Wager et al.   ACS Chemical Neuroscience

Safety and pharmacokinetics of nintedanib and pirfenidone in idiopathic pulmonary fibrosis

(2014) Takashi Ogura et al.   EUROPEAN RESPIRATORY JOURNAL

Pathogenesis of idiopathic pulmonary fibrosis and its clinical implications

(2014) Paolo Spagnolo et al.   Expert Review of Clinical Immunology

The circadian clock regulates rhythmic activation of the NRF2/glutathione-mediated antioxidant defense pathway to modulate pulmonary fibrosis

(2014) V. Pekovic-Vaughan et al.   GENES & DEVELOPMENT

Acute inhibition of casein kinase 1δ/ε rapidly delays peripheral clock gene rhythms

(2014) D. J. Kennaway et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

A Phase 3 Trial of Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis

(2014) Talmadge E. King et al.   NEW ENGLAND JOURNAL OF MEDICINE

Efficacy and Safety of Nintedanib in Idiopathic Pulmonary Fibrosis

(2014) Luca Richeldi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Bronchial epithelial cells are rendered insensitive to glucocorticoid transactivation by transforming growth factor-β1

(2014) Christine R Keenan et al.   RESPIRATORY RESEARCH

Authors’ response: Epithelial-mesenchymal Transition (EMT) is a common molecular programme in epithelial cells which can be triggered by injury

(2014) Domokos Bartis et al.   THORAX

Pathogenesis of Idiopathic Pulmonary Fibrosis

(2013) Paul J. Wolters et al.   Annual Review of Pathology-Mechanisms of Disease

Therapy for Fibrotic Diseases: Nearing the Starting Line

(2013) S. L. Friedman et al.   Science Translational Medicine

Epithelial–mesenchymal transition in lung development and disease: does it exist and is it important?

(2013) Domokos Bartis et al.   THORAX

The circadian clock and asthma

(2013) Hannah J Durrington et al.   THORAX

Transforming Growth Factor–β–Induced Differentiation of Airway Smooth Muscle Cells Is Inhibited by Fibroblast Growth Factor–2

(2012) Michael Schuliga et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Matrices of Physiologic Stiffness Potently Inactivate Idiopathic Pulmonary Fibrosis Fibroblasts

(2012) Aleksandar Marinković et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Transforming growth factor-β impairs glucocorticoid activity in the A549 lung adenocarcinoma cell line

(2012) S Salem et al.   BRITISH JOURNAL OF PHARMACOLOGY

EMT and interstitial lung disease

(2012) Hidenori Kage et al.   CURRENT OPINION IN PULMONARY MEDICINE

New cellular and molecular mechanisms of lung injury and fibrosis in idiopathic pulmonary fibrosis

(2012) Isis E Fernandez et al.   LANCET

Inhibition of the Casein-Kinase-1-Epsilon/Delta Prevents Relapse-Like Alcohol Drinking

(2012) Stéphanie Perreau-Lenz et al.   NEUROPSYCHOPHARMACOLOGY

Prednisone, Azathioprine, andN-Acetylcysteine for Pulmonary Fibrosis

(2012)   NEW ENGLAND JOURNAL OF MEDICINE

An Official ATS/ERS/JRS/ALAT Statement: Idiopathic Pulmonary Fibrosis: Evidence-based Guidelines for Diagnosis and Management

(2011) Ganesh Raghu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

TGF-β signaling in fibrosis

(2011) Anna Biernacka et al.   GROWTH FACTORS

Induction of Heart Valve Lesions by Small-Molecule ALK5 Inhibitors

(2011) Mark J. Anderton et al.   TOXICOLOGIC PATHOLOGY

Clinical Course and Prediction of Survival in Idiopathic Pulmonary Fibrosis

(2010) Brett Ley et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Aspiration of Biological Viscoelastic Drops

(2010) Karine Guevorkian et al.   PHYSICAL REVIEW LETTERS

Entrainment of disrupted circadian behavior through inhibition of casein kinase 1 (CK1) enzymes

(2010) Q.-J. Meng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chronic treatment with a selective inhibitor of casein kinase I δ/ε yields cumulative phase delays in circadian rhythms

(2010) Jeffrey Sprouse et al.   PSYCHOPHARMACOLOGY

Fibrillar Collagen Clamps Lung Mesenchymal Cells in a Nonproliferative and Noncontractile Phenotype

(2009) Michael J. Schuliga et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Selective Inhibition of Casein Kinase 1  Minimally Alters Circadian Clock Period

(2009) K. M. Walton et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

A role for casein kinase 1 epsilon in the locomotor stimulant response to methamphetamine

(2008) Camron D. Bryant et al.   PSYCHOPHARMACOLOGY

Inhibition of Integrin αvβ6, an Activator of Latent Transforming Growth Factor-β, Prevents Radiation-induced Lung Fibrosis

(2007) Khalid Puthawala et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Partial Inhibition of Integrin αvβ6 Prevents Pulmonary Fibrosis without Exacerbating Inflammation

(2007) Gerald S. Horan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The bleomycin animal model: A useful tool to investigate treatment options for idiopathic pulmonary fibrosis?

(2007) Antje Moeller et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY