TGFβ-derived immune modulatory vaccine: targeting the immunosuppressive and fibrotic tumor microenvironment in a murine model of pancreatic cancer

Blockade of beta-adrenergic receptors reduces cancer growth and enhances the response to anti-CTLA4 therapy by modulating the tumor microenvironment

(2022) Klaire Yixin Fjæstad et al.   ONCOGENE

Developing a prediction model to estimate the true burden of respiratory syncytial virus (RSV) in hospitalised children in Western Australia

(2022) Amanuel Tesfay Gebremedhin et al.   Scientific Reports

Peptide vaccination activating Galectin-3-specific T cells offers a novel means to target Galectin-3-expressing cells in the tumor microenvironment

(2022) Simone Kloch Bendtsen et al.   OncoImmunology

European cancer mortality predictions for the year 2022 with focus on ovarian cancer

(2022) M. Dalmartello et al.   ANNALS OF ONCOLOGY

Randomized Phase II Study of Nivolumab With or Without Ipilimumab Combined With Stereotactic Body Radiotherapy for Refractory Metastatic Pancreatic Cancer (CheckPAC)

(2022) Inna M. Chen et al.   JOURNAL OF CLINICAL ONCOLOGY

Development of Peptide-Based Vaccines for Cancer

(2022) Noraini Abd-Aziz et al.   Journal of Oncology

Cytotoxic T cells isolated from healthy donors and cancer patients kill TGFβ-expressing cancer cells in a TGFβ-dependent manner

(2021) Morten Orebo Holmström et al.   Cellular & Molecular Immunology

Preclinical Models of Pancreatic Ductal Adenocarcinoma and Their Utility in Immunotherapy Studies

(2021) Thao N. D. Pham et al.   Cancers

Multi-omics analysis of tumor angiogenesis characteristics and potential epigenetic regulation mechanisms in renal clear cell carcinoma

(2021) Wenzhong Zheng et al.   Cell Communication and Signaling

Characterization of TGFβ-specific CD4+T cells through the modulation of TGFβ expression in malignant myeloid cells

(2021) Rasmus Erik Johansson Mortensen et al.   Cellular & Molecular Immunology

Pancreatic cancer: A review of epidemiology, trend, and risk factors

(2021) Jian-Xiong Hu et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Arginase 1-based immune modulatory vaccines induce anti-cancer immunity and synergize with anti-PD-1 checkpoint blockade

(2021) Mia Aaboe Jørgensen et al.   Cancer Immunology Research

Pancreatic Cancer and Immunotherapy: A Clinical Overview

(2021) Florentine E. F. Timmer et al.   Cancers

Current controversies and advances in the management of pancreatic adenocarcinoma

(2021) Muhammad Shehroz Zeeshan et al.   World Journal of Gastrointestinal Oncology

A phase 1/2 trial of an immune-modulatory vaccine against IDO/PD-L1 in combination with nivolumab in metastatic melanoma

(2021) Julie Westerlin Kjeldsen et al.   NATURE MEDICINE

Immune Modulatory Properties of Collagen in Cancer

(2021) Anne Mette Askehøj Rømer et al.   Frontiers in Immunology

TGFβ Signaling in the Pancreatic Tumor Microenvironment

(2021) Daniel R. Principe et al.   Cancers

The Scavenger Receptor MARCO Expressed by Tumor-Associated Macrophages Are Highly Associated With Poor Pancreatic Cancer Prognosis

(2021) Bian Shi et al.   Frontiers in Oncology

PHD1 controls muscle mTORC1 in a hydroxylation-independent manner by stabilizing leucyl tRNA synthetase

(2020) Gommaar D’Hulst et al.   Nature Communications

SLIM: Simultaneous Logic-in-Memory Computing Exploiting Bilayer Analog OxRAM Devices

(2020) Sandeep Kaur Kingra et al.   Scientific Reports

The tumour microenvironment in pancreatic cancer — clinical challenges and opportunities

(2020) Won Jin Ho et al.   Nature Reviews Clinical Oncology

Peptide vaccination directed against IDO1-expressing immune cells elicits CD8+ and CD4+ T-cell-mediated antitumor immunity and enhanced anti-PD1 responses

(2020) Souvik Dey et al.   Journal for ImmunoTherapy of Cancer

The peptide vaccine of the future

(2020) Annika Nelde et al.   MOLECULAR & CELLULAR PROTEOMICS

Transforming Growth Factor-β Signaling in Immunity and Cancer

(2019) Eduard Batlle et al.   IMMUNITY

Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts

(2019) Ela Elyada et al.   Cancer Discovery

Arginase-1-based vaccination against the tumor microenvironment: the identification of an optimal T-cell epitope

(2019) Evelina Martinenaite et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Inhibiting PAD2 enhances the anti-tumor effect of docetaxel in tamoxifen-resistant breast cancer cells

(2019) Fujun Li et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

The Balance Players of the Adaptive Immune System

(2018) Mads Hald Andersen   CANCER RESEARCH

Thrombospondin-1 regulation of latent TGF-β activation: A therapeutic target for fibrotic disease

(2018) Joanne E. Murphy-Ullrich et al.   MATRIX BIOLOGY

Third generation EGFR TKIs: current data and future directions

(2018) Chee-Seng Tan et al.   Molecular Cancer

The T-win® technology: immune-modulating vaccines

(2018) Mads Hald Andersen   Seminars in Immunopathology

No evidence that carotenoid pigments boost either immune or antioxidant defenses in a songbird

(2018) Rebecca E. Koch et al.   Nature Communications

TumGrowth: An open-access web tool for the statistical analysis of tumor growth curves

(2018) David P. Enot et al.   OncoImmunology

Galunisertib plus gemcitabine vs. gemcitabine for first-line treatment of patients with unresectable pancreatic cancer

(2018) Davide Melisi et al.   BRITISH JOURNAL OF CANCER

In situ click chemistry generation of cyclooxygenase-2 inhibitors

(2017) Atul Bhardwaj et al.   Nature Communications

Limb proportions show developmental plasticity in response to embryo movement

(2017) A. S. Pollard et al.   Scientific Reports

Anti-regulatory T cells

(2016) Mads Hald Andersen   Seminars in Immunopathology

Regulation of the Bioavailability of TGF-β and TGF-β-Related Proteins

(2016) Ian B. Robertson et al.   Cold Spring Harbor Perspectives in Biology

Gapped sequence alignment using artificial neural networks: application to the MHC class I system

(2015) Massimo Andreatta et al.   BIOINFORMATICS

Robust enumeration of cell subsets from tissue expression profiles

(2015) Aaron M Newman et al.   NATURE METHODS

Angiogenic gene signature in human pancreatic cancer correlates with TGF-beta and inflammatory transcriptomes

(2015) Kelly E. Craven et al.   Oncotarget

TCGA data and patient-derived orthotopic xenografts highlight pancreatic cancer-associated angiogenesis

(2015) Jesse Gore et al.   Oncotarget

Short Peptide Vaccine Induces CD4+ T Helper Cells in Patients with Different Solid Cancers

(2015) S. Gross et al.   Cancer Immunology Research

Spatial distribution of B cells predicts prognosis in human pancreatic adenocarcinoma

(2015) Giovanni Francesco Castino et al.   OncoImmunology

The immune checkpoint regulator PD-L1 is a specific target for naturally occurring CD4+T cells

(2013) Shamaila Munir et al.   OncoImmunology

Indoleamine 2,3-dioxygenase specific, cytotoxic T cells as immune regulators

(2010) R. B. Sorensen et al.   BLOOD

Tumor-derived TGF-β Mediates Conversion of CD4+Foxp3+ Regulatory T Cells in a Murine Model of Pancreas Cancer

(2008) Tricia A. Moo-Young et al.   JOURNAL OF IMMUNOTHERAPY