Activin/Smad2-induced Histone H3 Lys-27 Trimethylation (H3K27me3) Reduction Is Crucial to Initiate Mesendoderm Differentiation of Human Embryonic Stem Cells

Signaling Control of Differentiation of Embryonic Stem Cells toward Mesendoderm

(2016) Lu Wang et al.   JOURNAL OF MOLECULAR BIOLOGY

β-Catenin Regulates Primitive Streak Induction through Collaborative Interactions with SMAD2/SMAD3 and OCT4

(2015) Nina S. Funa et al.   Cell Stem Cell

Activin/Nodal signaling and NANOG orchestrate human embryonic stem cell fate decisions by controlling the H3K4me3 chromatin mark

(2015) Alessandro Bertero et al.   GENES & DEVELOPMENT

SMADs and YAP Compete to Control Elongation of β-Catenin:LEF-1-Recruited RNAPII during hESC Differentiation

(2015) Conchi Estarás et al.   MOLECULAR CELL

Chromatin architecture reorganization during stem cell differentiation

(2015) Jesse R. Dixon et al.   NATURE

Transcription factor binding dynamics during human ES cell differentiation

(2015) Alexander M. Tsankov et al.   NATURE

HEB associates with PRC2 and SMAD2/3 to regulate developmental fates

(2015) Se-Jin Yoon et al.   Nature Communications

Polycomb group protein expression during differentiation of human embryonic stem cells into pancreatic lineage in vitro

(2014) Prasad Pethe et al.   BMC CELL BIOLOGY

NANOG and CDX2 Pattern Distinct Subtypes of Human Mesoderm during Exit from Pluripotency

(2014) Sasha Mendjan et al.   Cell Stem Cell

Comparative analysis of regulatory information and circuits across distant species

(2014) Alan P. Boyle et al.   NATURE

TGF-β signaling to chromatin: How Smads regulate transcription during self-renewal and differentiation

(2014) Tessa Gaarenstroom et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Relating genes to function: identifying enriched transcription factors using the ENCODE ChIP-Seq significance tool

(2013) Raymond K. Auerbach et al.   BIOINFORMATICS

Epigenomic Analysis of Multilineage Differentiation of Human Embryonic Stem Cells

(2013) Wei Xie et al.   CELL

Dynamic Chromatin Remodeling Mediated by Polycomb Proteins Orchestrates Pancreatic Differentiation of Human Embryonic Stem Cells

(2013) Ruiyu Xie et al.   Cell Stem Cell

The histone demethylase Jmjd3 sequentially associates with the transcription factors Tbx3 and Eomes to drive endoderm differentiation

(2013) Apriliana E R Kartikasari et al.   EMBO JOURNAL

A double take on bivalent promoters

(2013) P. Voigt et al.   GENES & DEVELOPMENT

Chromatin modifiers and remodellers: regulators of cellular differentiation

(2013) Taiping Chen et al.   NATURE REVIEWS GENETICS

Switch Enhancers Interpret TGF-β and Hippo Signaling to Control Cell Fate in Human Embryonic Stem Cells

(2013) Tobias A. Beyer et al.   Cell Reports

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Histone H3K27me3 demethylases KDM6A and KDM6B modulate definitive endoderm differentiation from human ESCs by regulating WNT signaling pathway

(2012) Wei Jiang et al.   CELL RESEARCH

Signaling Network Crosstalk in Human Pluripotent Cells: A Smad2/3-Regulated Switch that Controls the Balance between Self-Renewal and Differentiation

(2012) Amar M. Singh et al.   Cell Stem Cell

GENCODE: The reference human genome annotation for The ENCODE Project

(2012) J. Harrow et al.   GENOME RESEARCH

Navigating the epigenetic landscape of pluripotent stem cells

(2012) Mo Li et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A Poised Chromatin Platform for TGF-β Access to Master Regulators

(2011) Qiaoran Xi et al.   CELL

Control of the Embryonic Stem Cell State

(2011) Richard A. Young   CELL

BRACHYURY and CDX2 Mediate BMP-Induced Differentiation of Human and Mouse Pluripotent Stem Cells into Embryonic and Extraembryonic Lineages

(2011) Andreia S. Bernardo et al.   Cell Stem Cell

FGF2 Sustains NANOG and Switches the Outcome of BMP4-Induced Human Embryonic Stem Cell Differentiation

(2011) Pengzhi Yu et al.   Cell Stem Cell

The Polycomb complex PRC2 and its mark in life

(2011) Raphaël Margueron et al.   NATURE

Epigenetic Changes with Dietary Soy in Cynomolgus Monkeys

(2011) Timothy D. Howard et al.   PLoS One

Activin/Nodal Signaling Controls Divergent Transcriptional Networks in Human Embryonic Stem Cells and in Endoderm Progenitors

(2011) Stephanie Brown et al.   STEM CELLS

Smad2 mediates Activin/Nodal signaling in mesendoderm differentiation of mouse embryonic stem cells

(2010) Teng Fei et al.   CELL RESEARCH

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Nodal Signaling Recruits the Histone Demethylase Jmjd3 to Counteract Polycomb-Mediated Repression at Target Genes

(2010) O. Dahle et al.   Science Signaling

Robust Enhancement of Neural Differentiation from Human ES and iPS Cells Regardless of their Innate Difference in Differentiation Propensity

(2010) Dae-Sung Kim et al.   Stem Cell Reviews and Reports

Transforming Growth Factor type β and Smad family signaling in stem cell function

(2009) Eve Seuntjens et al.   CYTOKINE & GROWTH FACTOR REVIEWS

DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation

(2009) T. B. Miranda et al.   MOLECULAR CANCER THERAPEUTICS

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

(2009) Stuart M Chambers et al.   NATURE BIOTECHNOLOGY

Signaling Pathways Controlling Pluripotency and Early Cell Fate Decisions of Human Induced Pluripotent Stem Cells

(2009) Ludovic Vallier et al.   STEM CELLS

Differentiation of Embryonic Stem Cells to Clinically Relevant Populations: Lessons from Embryonic Development

(2008) Charles E. Murry et al.   CELL

EZH1 Mediates Methylation on Histone H3 Lysine 27 and Complements EZH2 in Maintaining Stem Cell Identity and Executing Pluripotency

(2008) Xiaohua Shen et al.   MOLECULAR CELL

Genome-scale DNA methylation maps of pluripotent and differentiated cells

(2008) Alexander Meissner et al.   NATURE

A model for transmission of the H3K27me3 epigenetic mark

(2008) Klaus H. Hansen et al.   NATURE CELL BIOLOGY