Nano-bio interactions in mRNA nanomedicine: Challenges and opportunities for targeted mRNA delivery
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Title
Nano-bio interactions in mRNA nanomedicine: Challenges and opportunities for targeted mRNA delivery
Authors
Keywords
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Journal
ADVANCED DRUG DELIVERY REVIEWS
Volume -, Issue -, Pages 115116
Publisher
Elsevier BV
Online
2023-10-21
DOI
10.1016/j.addr.2023.115116
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Note: Only part of the references are listed.- Interactions of Apolipoproteins with Lipid-Based Nanoparticles
- (2023) Paul Dalhaimer et al. ACS Nano
- Effect of Cholesterol Content of Lipid Composition in mRNA-LNPs on the Protein Expression in the Injected Site and Liver After Local Administration in Mice
- (2023) Maho Kawaguchi et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Spleen-Targeted mRNA Delivery by Amphiphilic Carbon Dots for Tumor Immunotherapy
- (2023) Ping Chen et al. ACS Applied Materials & Interfaces
- Use of a Liver-Targeting Immune-Tolerogenic mRNA Lipid Nanoparticle Platform to Treat Peanut-Induced Anaphylaxis by Single- and Multiple-Epitope Nucleotide Sequence Delivery
- (2023) Xiao Xu et al. ACS Nano
- Visible Light Conjugation with Triazolinediones as a Route to Degradable Poly(ethylene glycol)–Lipids for mRNA Lipid Nanoparticle Formulation
- (2023) Bianka Golba et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Lysine-Derived Charge-Altering Releasable Transporters: Targeted Delivery of mRNA and siRNA to the Lungs
- (2023) Timothy R. Blake et al. Bioconjugate Chemistry
- Precise and systematic end group chemistry modifications on PAMAM and poly(l-lysine) dendrimers to improve cytosolic delivery of mRNA
- (2023) Fanny Joubert et al. JOURNAL OF CONTROLLED RELEASE
- An Efficacy and Mechanism Driven Study on the Impact of Hypoxia on Lipid Nanoparticle Mediated mRNA Delivery
- (2023) Yutian Ma et al. Journal of the American Chemical Society
- Nanoparticle stereochemistry-dependent endocytic processing improves in vivo mRNA delivery
- (2023) Marine Z. C. Hatit et al. Nature Chemistry
- Biodegradable lipophilic polymeric mRNA nanoparticles for ligand-free targeting of splenic dendritic cells for cancer vaccination
- (2023) Elana Ben-Akiva et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Development of Cell-Penetrating Peptides for Efficient and Selective In Vivo Expression of mRNA in Spleen Tissue
- (2023) Ly Porosk et al. Pharmaceutics
- Effect of Cell Membrane‐cloaked Nanoparticle Elasticity on Nano‐Bio Interaction
- (2023) Pengfei Yuan et al. Small Methods
- Biomimetic Mineralized CRISPR/Cas RNA Nanoparticles for Efficient Tumor-Specific Multiplex Gene Editing
- (2023) Yan Liang et al. ACS Nano
- Polymeric nanoparticle gel for intracellular mRNA delivery and immunological reprogramming of tumors
- (2023) Sarah Y. Neshat et al. BIOMATERIALS
- Understanding structure activity relationships of Good HEPES lipids for lipid nanoparticle mRNA vaccine applications
- (2023) Rebecca L. Goldman et al. BIOMATERIALS
- The interplay of quaternary ammonium lipid structure and protein corona on lung-specific mRNA delivery by selective organ targeting (SORT) nanoparticles
- (2023) Sean A. Dilliard et al. JOURNAL OF CONTROLLED RELEASE
- The role of protein corona on nanodrugs for organ-targeting and its prospects of application
- (2023) Sijie Wang et al. JOURNAL OF CONTROLLED RELEASE
- The exit of nanoparticles from solid tumours
- (2023) Luan N. M. Nguyen et al. NATURE MATERIALS
- Effects of cholesterol on biomolecular corona
- (2023) Negar Mahmoudi et al. Nature Nanotechnology
- Cholesterol modulates the physiological response to nanoparticles by changing the composition of protein corona
- (2023) Huan Tang et al. Nature Nanotechnology
- In vivo hematopoietic stem cell modification by mRNA delivery
- (2023) Laura Breda et al. SCIENCE
- Phase-separating peptides for direct cytosolic delivery and redox-activated release of macromolecular therapeutics
- (2022) Yue Sun et al. Nature Chemistry
- Lung-selective mRNA delivery of synthetic lipid nanoparticles for the treatment of pulmonary lymphangioleiomyomatosis
- (2022) Min Qiu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CAR T cells produced in vivo to treat cardiac injury
- (2022) Joel G. Rurik et al. SCIENCE
- Engineering surface patterns on nanoparticles: New insights on nano-bio interactions
- (2022) Boyang Hu et al. Journal of Materials Chemistry B
- The Potential of Nanomedicine to Unlock the Limitless Applications of mRNA
- (2022) Laura Taina-González et al. Pharmaceutics
- Anionic Lipid Nanoparticles Preferentially Deliver mRNA to the Hepatic Reticuloendothelial System
- (2022) Roy Pattipeiluhu et al. ADVANCED MATERIALS
- Branched PEG-modification: A new strategy for nanocarriers to evade of the accelerated blood clearance phenomenon and enhance anti-tumor efficacy
- (2022) Min Liu et al. BIOMATERIALS
- The replacement of helper lipids with charged alternatives in lipid nanoparticles facilitates targeted mRNA delivery to the spleen and lungs
- (2022) Samuel T. LoPresti et al. JOURNAL OF CONTROLLED RELEASE
- Delivery of modified mRNA to damaged myocardium by systemic administration of lipid nanoparticles
- (2022) Martijn J.W. Evers et al. JOURNAL OF CONTROLLED RELEASE
- Targeting nucleic acid-based therapeutics to tumors: Challenges and strategies for polyplexes
- (2022) Victoria C. Vetter et al. JOURNAL OF CONTROLLED RELEASE
- Enhancing CRISPR/Cas gene editing through modulating cellular mechanical properties for cancer therapy
- (2022) Di Zhang et al. Nature Nanotechnology
- Dynamic intracellular exchange of nanomaterials’ protein corona perturbs proteostasis and remodels cell metabolism
- (2022) Rong Cai et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Temperature, concentration, and surface modification influence the cellular uptake and the protein corona of polystyrene nanoparticles
- (2022) J. Oberländer et al. Acta Biomaterialia
- The effects of protein corona on in vivo fate of nanocarriers
- (2022) Qingqing Xiao et al. ADVANCED DRUG DELIVERY REVIEWS
- Lipid‐Polymer Hybrid “Particle‐in‐Particle” Nanostructure Gene Delivery Platform Explored for Lyophilizable DNA and mRNA COVID‐19 Vaccines
- (2022) Zhongyu Li et al. ADVANCED FUNCTIONAL MATERIALS
- mRNA Vaccines Against SARS‐CoV‐2 Variants Delivered by Lipid Nanoparticles Based on Novel Ionizable Lipids
- (2022) Kepan Chen et al. ADVANCED FUNCTIONAL MATERIALS
- Conjugating Ligands to an Equilibrated Nanoparticle Protein Corona Enables Cell Targeting in Serum
- (2022) Benjamin Stordy et al. CHEMISTRY OF MATERIALS
- Focused ultrasound/microbubbles-assisted BBB opening enhances LNP-mediated mRNA delivery to brain
- (2022) Koki Ogawa et al. JOURNAL OF CONTROLLED RELEASE
- Lipid-peptide nanocomplexes for mRNA delivery in vitro and in vivo
- (2022) Dania Grant-Serroukh et al. JOURNAL OF CONTROLLED RELEASE
- Engineering Lipid Nanoparticles for Enhanced Intracellular Delivery of mRNA through Inhalation
- (2022) Jeonghwan Kim et al. ACS Nano
- Extrahepatic targeting of lipid nanoparticles in vivo with intracellular targeting for future nanomedicines
- (2022) Takashi Nakamura et al. ADVANCED DRUG DELIVERY REVIEWS
- Enhanced Competition at the Nano–Bio Interface Enables Comprehensive Characterization of Protein Corona Dynamics and Deep Coverage of Proteomes
- (2022) Shadi Ferdosi et al. ADVANCED MATERIALS
- Phosphatidylserine Lipid Nanoparticles Promote Systemic RNA Delivery to Secondary Lymphoid Organs
- (2022) Sijin Luozhong et al. NANO LETTERS
- Morphology-directed radiosensitization of MoSe2 nanoplatforms for promoting cervical cancer radiotherapy
- (2022) Wenxiao Jiang et al. Nano Today
- Preparation of selective organ-targeting (SORT) lipid nanoparticles (LNPs) using multiple technical methods for tissue-specific mRNA delivery
- (2022) Xu Wang et al. Nature Protocols
- Interaction Kinetics of Individual mRNA-Containing Lipid Nanoparticles with an Endosomal Membrane Mimic: Dependence on pH, Protein Corona Formation, and Lipoprotein Depletion
- (2022) Nima Aliakbarinodehi et al. ACS Nano
- Hybrid core-shell particles for mRNA systemic delivery
- (2022) Valentina Andretto et al. JOURNAL OF CONTROLLED RELEASE
- The landscape of mRNA nanomedicine
- (2022) Xiangang Huang et al. NATURE MEDICINE
- Nanoparticle elasticity regulates the formation of cell membrane-coated nanoparticles and their nano-bio interactions
- (2022) Da Zou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lipid nanoparticle-based mRNA candidates elicit potent T cell responses
- (2022) Ye Zeng et al. Biomaterials Science
- Biomimetic calcium carbonate nanoparticles delivered IL-12 mRNA for targeted glioblastoma sono-immunotherapy by ultrasound-induced necroptosis
- (2022) Pengxuan Zhao et al. JOURNAL OF NANOBIOTECHNOLOGY
- Ionizable lipid nanoparticles for in utero mRNA delivery
- (2021) Rachel S. Riley et al. Science Advances
- Reports of Anaphylaxis After Receipt of mRNA COVID-19 Vaccines in the US—December 14, 2020-January 18, 2021
- (2021) Tom T. Shimabukuro et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- mRNA vaccine for cancer immunotherapy
- (2021) Lei Miao et al. Molecular Cancer
- In Situ Transforming RNA Nanovaccines from Polyethylenimine Functionalized Graphene Oxide Hydrogel for Durable Cancer Immunotherapy
- (2021) Yue Yin et al. NANO LETTERS
- Lipid nanoparticle-mediated codelivery of Cas9 mRNA and single-guide RNA achieves liver-specific in vivo genome editing of Angptl3
- (2021) Min Qiu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeted drug delivery strategies for precision medicines
- (2021) Mandana T. Manzari et al. Nature Reviews Materials
- Cytosolic Delivery of Nucleic Acids: The case of Ionizable Lipid Nanoparticles
- (2021) Michele Schlich et al. Bioengineering & Translational Medicine
- Apolipoprotein E Binding Drives Structural and Compositional Rearrangement of mRNA-Containing Lipid Nanoparticles
- (2021) Federica Sebastiani et al. ACS Nano
- Enhancement of target toxin neutralization effect in vivo by PEGylation of multifunctionalized lipid nanoparticles
- (2021) Hiroyuki Koide et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- PEGylation of poly(amine-co-ester) polyplexes for tunable gene delivery
- (2021) Molly K. Grun et al. BIOMATERIALS
- Recent Advances in Preclinical Research Using PAMAM Dendrimers for Cancer Gene Therapy
- (2021) Piotr Tarach et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Secreted Expression of mRNA‐Encoded Truncated ACE2 Variants for SARS‐CoV‐2 via Lipid‐Like Nanoassemblies
- (2021) Min Li et al. ADVANCED MATERIALS
- Lipids and Lipid Derivatives for RNA Delivery
- (2021) Yuebao Zhang et al. CHEMICAL REVIEWS
- Lipid Nanoparticle Spherical Nucleic Acids for Intracellular DNA and RNA Delivery
- (2021) Andrew J. Sinegra et al. NANO LETTERS
- Obstacles and opportunities in a forward vision for cancer nanomedicine
- (2021) Irene de Lázaro et al. NATURE MATERIALS
- CRISPR-Cas9 In Vivo Gene Editing for Transthyretin Amyloidosis
- (2021) Julian D. Gillmore et al. NEW ENGLAND JOURNAL OF MEDICINE
- Lipid nanoparticles for mRNA delivery
- (2021) Xucheng Hou et al. Nature Reviews Materials
- Chemistry of Lipid Nanoparticles for RNA Delivery
- (2021) Yulia Eygeris et al. ACCOUNTS OF CHEMICAL RESEARCH
- Lipid Nanoparticle–mRNA Formulations for Therapeutic Applications
- (2021) Chang Wang et al. ACCOUNTS OF CHEMICAL RESEARCH
- Nanoparticle designs for delivery of nucleic acid therapeutics as brain cancer therapies
- (2021) Johan Karlsson et al. ADVANCED DRUG DELIVERY REVIEWS
- Virus‐Mimicking Cell Membrane‐Coated Nanoparticles for Cytosolic Delivery of mRNA
- (2021) Joon Ho Park et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- A scalable and robust cationic lipid/polymer hybrid nanoparticle platform for mRNA delivery
- (2021) Randall A. Meyer et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Endosomal escape of delivered mRNA from endosomal recycling tubules visualized at the nanoscale
- (2021) Prasath Paramasivam et al. JOURNAL OF CELL BIOLOGY
- Design of a new cell penetrating peptide for DNA, siRNA and mRNA delivery
- (2021) Salif Ali et al. JOURNAL OF GENE MEDICINE
- Zwitterionic Phospholipidation of Cationic Polymers Facilitates Systemic mRNA Delivery to Spleen and Lymph Nodes
- (2021) Shuai Liu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Clinical progress of nanomedicine-based RNA therapies
- (2021) Siyoung A. Lim et al. Bioactive Materials
- A Combinatorial Library of Lipid Nanoparticles for RNA Delivery to Leukocytes
- (2020) Srinivas Ramishetti et al. ADVANCED MATERIALS
- New approaches to genetic therapies for cystic fibrosis
- (2020) A. Christopher Boyd et al. Journal of Cystic Fibrosis
- Quantitating Endosomal Escape of a Library of Polymers for mRNA Delivery
- (2020) Yuhang Jiang et al. NANO LETTERS
- Selective targeting of nanomedicine to inflamed cerebral vasculature to enhance the blood–brain barrier
- (2020) Oscar A. Marcos-Contreras et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Engineering Caveolae-Targeted Lipid Nanoparticles To Deliver mRNA to the Lungs
- (2020) Qing Li et al. ACS Chemical Biology
- Polyglycerol Grafting Shields Nanoparticles from Protein Corona Formation to Avoid Macrophage Uptake
- (2020) Yajuan Zou et al. ACS Nano
- A phase I study of mRNA-2752, a lipid nanoparticle encapsulating mRNAs encoding human OX40L, IL-23, and IL-36γ, for intratumoral (iTu) injection alone and in combination with durvalumab.
- (2020) Manish R. Patel et al. JOURNAL OF CLINICAL ONCOLOGY
- Selective organ targeting (SORT) nanoparticles for tissue-specific mRNA delivery and CRISPR–Cas gene editing
- (2020) Qiang Cheng et al. Nature Nanotechnology
- Nano-bio interactions: the implication of size-dependent biological effects of nanomaterials
- (2020) Xiaoyu Wang et al. Science China-Life Sciences
- The Influence of Nanoparticle Shape on Protein Corona Formation
- (2020) Rahul Madathiparambil Visalakshan et al. Small
- Synergistic lipid compositions for albumin receptor mediated delivery of mRNA to the liver
- (2020) Lei Miao et al. Nature Communications
- Surface-Functionalized PEGylated Nanoparticles Deliver Messenger RNA to Pulmonary Immune Cells
- (2020) Xiyu Ke et al. ACS Applied Materials & Interfaces
- Intranasal delivery of cationic liposome-protamine complex mRNA vaccine elicits effective anti-tumor immunity
- (2020) Yaping Mai et al. CELLULAR IMMUNOLOGY
- A Potent Branched-Tail Lipid Nanoparticle Enables Multiplexed mRNA Delivery and Gene Editing In Vivo
- (2020) Khalid A. Hajj et al. NANO LETTERS
- Rapid, deep and precise profiling of the plasma proteome with multi-nanoparticle protein corona
- (2020) John E. Blume et al. Nature Communications
- Systemic nanoparticle delivery of CRISPR-Cas9 ribonucleoproteins for effective tissue specific genome editing
- (2020) Tuo Wei et al. Nature Communications
- Theranostic dendrimer-based lipid nanoparticles containing PEGylated BODIPY dyes for tumor imaging and systemic mRNA delivery in vivo
- (2020) Hu Xiong et al. JOURNAL OF CONTROLLED RELEASE
- Nanomedicine-Based Approaches for mRNA Delivery
- (2020) Satoshi Uchida et al. MOLECULAR PHARMACEUTICS
- Personalized Cancer Vaccines: Clinical Landscape, Challenges, and Opportunities
- (2020) Colby S. Shemesh et al. MOLECULAR THERAPY
- A materials-science perspective on tackling COVID-19
- (2020) Zhongmin Tang et al. Nature Reviews Materials
- A Systematic Study of Unsaturation in Lipid Nanoparticles Leads to Improved mRNA Transfection In Vivo
- (2020) Sang Lee et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Bundling of mRNA strands inside polyion complexes improves mRNA delivery efficiency in vitro and in vivo
- (2020) Kyoko Koji et al. BIOMATERIALS
- Engineering precision nanoparticles for drug delivery
- (2020) Michael J. Mitchell et al. NATURE REVIEWS DRUG DISCOVERY
- Novel therapeutic approaches for the management of cystic fibrosis
- (2020) Ryan Jaques et al. MULTIDISCIPLINARY RESPIRATORY MEDICINE
- Branched-Tail Lipid Nanoparticles Potently Deliver mRNA In Vivo due to Enhanced Ionization at Endosomal pH
- (2019) Khalid A. Hajj et al. Small
- Durable anticancer immunity from intratumoral administration of IL-23, IL-36γ, and OX40L mRNAs
- (2019) Susannah L. Hewitt et al. Science Translational Medicine
- How mRNA therapeutics are entering the monoclonal antibody field
- (2019) Lien Van Hoecke et al. Journal of Translational Medicine
- Concepts of nanoparticle cellular uptake, intracellular trafficking, and kinetics in nanomedicine
- (2019) Nathan D. Donahue et al. ADVANCED DRUG DELIVERY REVIEWS
- Biomimetic Nanotherapies: Red Blood Cell Based Core–Shell Structured Nanocomplexes for Atherosclerosis Management
- (2019) Yi Wang et al. Advanced Science
- The Nano–Bio Interactions of Nanomedicines: Understanding the Biochemical Driving Forces and Redox Reactions
- (2019) Yaling Wang et al. ACCOUNTS OF CHEMICAL RESEARCH
- Understanding the Chemical Nature of Nanoparticle–Protein Interactions
- (2019) Didar Baimanov et al. BIOCONJUGATE CHEMISTRY
- Precision Nanomedicine Development Based on Specific Opsonization of Human Cancer Patient-Personalized Protein Coronas
- (2019) Jiayu Ren et al. NANO LETTERS
- Tailoring the lipid composition of nanoparticles modulates their cellular uptake and affects the viability of triple negative breast cancer cells
- (2019) Hanan Abumanhal-Masarweh et al. JOURNAL OF CONTROLLED RELEASE
- Immunological Analysis of a CCHFV mRNA Vaccine Candidate in Mouse Models
- (2019) Touraj Aligholipour Farzani et al. Vaccines
- Linkage between endosomal escape of LNP-mRNA and loading into EVs for transport to other cells
- (2019) Marco Maugeri et al. Nature Communications
- Ionizable Amino-Polyesters Synthesized via Ring Opening Polymerization of Tertiary Amino-Alcohols for Tissue Selective mRNA Delivery
- (2018) Piotr S. Kowalski et al. ADVANCED MATERIALS
- Virus-Like Particle Engineering: From Rational Design to Versatile Applications
- (2018) Xuanwei Ding et al. Biotechnology Journal
- Lipid Polymer Hybrid Nanomaterials for mRNA Delivery
- (2018) Weiyu Zhao et al. Cellular and Molecular Bioengineering
- The proton sponge hypothesis: Fable or fact?
- (2018) Lotte M.P. Vermeulen et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- A Novel Amino Lipid Series for mRNA Delivery: Improved Endosomal Escape and Sustained Pharmacology and Safety in Non-human Primates
- (2018) Staci Sabnis et al. MOLECULAR THERAPY
- Pre-adsorption of antibodies enables targeting of nanocarriers despite a biomolecular corona
- (2018) Manuel Tonigold et al. Nature Nanotechnology
- mRNA vaccines — a new era in vaccinology
- (2018) Norbert Pardi et al. NATURE REVIEWS DRUG DISCOVERY
- Enhanced mRNA delivery into lymphocytes enabled by lipid-varied libraries of charge-altering releasable transporters
- (2018) Colin J. McKinlay et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Personalized vaccines for cancer immunotherapy
- (2018) Ugur Sahin et al. SCIENCE
- Progress and challenges towards targeted delivery of cancer therapeutics
- (2018) Daniel Rosenblum et al. Nature Communications
- A Single Administration of CRISPR/Cas9 Lipid Nanoparticles Achieves Robust and Persistent In Vivo Genome Editing
- (2018) Jonathan D. Finn et al. Cell Reports
- Regulating the Golgi apparatus by co-delivery of a COX-2 inhibitor and Brefeldin A for suppression of tumor metastasis
- (2018) Ru-Yi Yu et al. Biomaterials Science
- Virus-Like Particle Engineering: From Rational Design to Versatile Applications
- (2018) Xuanwei Ding et al. Biotechnology Journal
- Correlation of the cytotoxic effects of cationic lipids with their headgroups
- (2018) Shaohui Cui et al. Toxicology Research
- Customizable Lipid Nanoparticle Materials for the Delivery of siRNAs and mRNAs
- (2018) Owen S. Fenton et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Mannose-functionalized Nanoscaffolds for Targeted Delivery in Biomedical Applications
- (2018) Jian Yin et al. Chemistry-An Asian Journal
- Polyethylenimine-Spherical Nucleic Acid Nanoparticles Against Gli1 Reduce the Chemoresistance and Stemness of Glioblastoma Cells
- (2018) Jilian R. Melamed et al. MOLECULAR PHARMACEUTICS
- Optimization of a Degradable Polymer–Lipid Nanoparticle for Potent Systemic Delivery of mRNA to the Lung Endothelium and Immune Cells
- (2018) James C. Kaczmarek et al. NANO LETTERS
- mRNA vaccination with charge-altering releasable transporters elicits human T cell responses and cures established tumors in mice
- (2018) Ole A. W. Haabeth et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nucleoside-modified mRNA immunization elicits influenza virus hemagglutinin stalk-specific antibodies
- (2018) Norbert Pardi et al. Nature Communications
- Kinetics of mRNA delivery and protein translation in dendritic cells using lipid-coated PLGA nanoparticles
- (2018) Hanzey Yasar et al. JOURNAL OF NANOBIOTECHNOLOGY
- Optimization of the Linker Length of Mannose-Cholesterol Conjugates for Enhanced mRNA Delivery to Dendritic Cells by Liposomes
- (2018) Fazhan Wang et al. Frontiers in Pharmacology
- Super-resolution Imaging of Proton Sponge-Triggered Rupture of Endosomes and Cytosolic Release of Small Interfering RNA
- (2018) Marcin Wojnilowicz et al. ACS Nano
- Efficient mRNA delivery system utilizing chimeric VSVG-L7Ae virus-like particles
- (2018) Yulia Zhitnyuk et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The Endosomal Escape of Nanoparticles: Toward More Efficient Cellular Delivery
- (2018) Samuel A. Smith et al. BIOCONJUGATE CHEMISTRY
- Size-Dependent Transport and Cytotoxicity of Mitomycin-Gold Nanoparticle Conjugates in 2D and 3D Mammalian Cell Models
- (2018) Isabel García et al. BIOCONJUGATE CHEMISTRY
- PECAM-1 directed re-targeting of exogenous mRNA providing two orders of magnitude enhancement of vascular delivery and expression in lungs independent of apolipoprotein E-mediated uptake
- (2018) Hamideh Parhiz et al. JOURNAL OF CONTROLLED RELEASE
- Insight into Cellular Uptake and Intracellular Trafficking of Nanoparticles
- (2018) Parisa Foroozandeh et al. Nanoscale Research Letters
- Cell specific delivery of modified mRNA expressing therapeutic proteins to leukocytes
- (2018) Nuphar Veiga et al. Nature Communications
- Protein corona: a new approach for nanomedicine design
- (2017) Van Hong Nguyen et al. International Journal of Nanomedicine
- Modified mRNA-Based Vaccines Elicit Robust Immune Responses and Protect Guinea Pigs From Ebola Virus Disease
- (2017) Michelle Meyer et al. JOURNAL OF INFECTIOUS DISEASES
- PEGylation of the GALA Peptide Enhances the Lung-Targeting Activity of Nanocarriers That Contain Encapsulated siRNA
- (2017) Sarochin Santiwarangkool et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Multivalency Effect of TAT-Peptide-Functionalized Nanoparticle in Cellular Endocytosis and Subcellular Trafficking
- (2017) Chumki Dalal et al. JOURNAL OF PHYSICAL CHEMISTRY B
- A Targeted and Stable Polymeric Nanoformulation Enhances Systemic Delivery of mRNA to Tumors
- (2017) Qixian Chen et al. MOLECULAR THERAPY
- Experimental separation steps influence the protein content of corona around mesoporous silica nanoparticles
- (2017) C. Pisani et al. Nanoscale
- Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing
- (2017) Hao Yin et al. NATURE BIOTECHNOLOGY
- Exosomes: Therapy delivery tools and biomarkers of diseases
- (2017) Lucio Barile et al. PHARMACOLOGY & THERAPEUTICS
- Charge-altering releasable transporters (CARTs) for the delivery and release of mRNA in living animals
- (2017) Colin J. McKinlay et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nanoescapology: progress toward understanding the endosomal escape of polymeric nanoparticles
- (2017) Laura I. Selby et al. Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology
- Arginine-Rich Peptide-Based mRNA Nanocomplexes Efficiently Instigate Cytotoxic T Cell Immunity Dependent on the Amphipathic Organization of the Peptide
- (2017) Vimal K. Udhayakumar et al. Advanced Healthcare Materials
- Bypassing Protein Corona Issue on Active Targeting: Zwitterionic Coatings Dictate Specific Interactions of Targeting Moieties and Cell Receptors
- (2016) Reihaneh Safavi-Sohi et al. ACS Applied Materials & Interfaces
- Mitochondria-Targeting Ceria Nanoparticles as Antioxidants for Alzheimer’s Disease
- (2016) Hyek Jin Kwon et al. ACS Nano
- Bioinspired Alkenyl Amino Alcohol Ionizable Lipid Materials for Highly Potent In Vivo mRNA Delivery
- (2016) Owen S. Fenton et al. ADVANCED MATERIALS
- Non-Viral CRISPR/Cas Gene Editing In Vitro and In Vivo Enabled by Synthetic Nanoparticle Co-Delivery of Cas9 mRNA and sgRNA
- (2016) Jason B. Miller et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Polymer-Lipid Nanoparticles for Systemic Delivery of mRNA to the Lungs
- (2016) James C. Kaczmarek et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Impact of protein pre-coating on the protein corona composition and nanoparticle cellular uptake
- (2016) Vahid Mirshafiee et al. BIOMATERIALS
- Enhanced intranasal delivery of mRNA vaccine by overcoming the nasal epithelial barrier via intra- and paracellular pathways
- (2016) Man Li et al. JOURNAL OF CONTROLLED RELEASE
- An ASGCT Perspective on the National Academies Genome Editing Summit
- (2016) Theodore Friedmann MOLECULAR THERAPY
- Lipid Nanoparticle Assisted mRNA Delivery for Potent Cancer Immunotherapy
- (2016) Matthias A. Oberli et al. NANO LETTERS
- Emerging understanding of the protein corona at the nano-bio interfaces
- (2016) Morteza Mahmoudi et al. Nano Today
- Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy
- (2016) Lena M. Kranz et al. NATURE
- Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo
- (2016) Hao Yin et al. NATURE BIOTECHNOLOGY
- Dendrimer-RNA nanoparticles generate protective immunity against lethal Ebola, H1N1 influenza, andToxoplasma gondiichallenges with a single dose
- (2016) Jasdave S. Chahal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Modular degradable dendrimers enable small RNAs to extend survival in an aggressive liver cancer model
- (2016) Kejin Zhou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Breakable Hybrid Organosilica Nanocapsules for Protein Delivery
- (2015) Eko Adi Prasetyanto et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- ER Stress Sensor XBP1 Controls Anti-tumor Immunity by Disrupting Dendritic Cell Homeostasis
- (2015) Juan R. Cubillos-Ruiz et al. CELL
- Optimization of Lipid Nanoparticle Formulations for mRNA Delivery in Vivo with Fractional Factorial and Definitive Screening Designs
- (2015) Kevin J. Kauffman et al. NANO LETTERS
- Targeted delivery of doxorubicin to mitochondria using mesoporous silica nanoparticle nanocarriers
- (2015) Qiuyu Qu et al. Nanoscale
- Principles of nanoparticle design for overcoming biological barriers to drug delivery
- (2015) Elvin Blanco et al. NATURE BIOTECHNOLOGY
- Towards Targeted Delivery Systems: Ligand Conjugation Strategies for mRNA Nanoparticle Tumor Vaccines
- (2015) Kyle K. L. Phua Journal of Immunology Research
- The nano-plasma interface: Implications of the protein corona
- (2014) Joy Wolfram et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- Lipid-based mRNA vaccine delivery systems
- (2014) Patrick Midoux et al. Expert Review of Vaccines
- Personalized protein coronas: a “key” factor at the nanobiointerface
- (2014) Mohammad J. Hajipour et al. Biomaterials Science
- Cancer nanotechnology: The impact of passive and active targeting in the era of modern cancer biology
- (2013) Nicolas Bertrand et al. ADVANCED DRUG DELIVERY REVIEWS
- Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction
- (2013) Lior Zangi et al. NATURE BIOTECHNOLOGY
- Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule corona adsorbs on the surface
- (2013) Anna Salvati et al. Nature Nanotechnology
- Transepithelial Transport of Fc-Targeted Nanoparticles by the Neonatal Fc Receptor for Oral Delivery
- (2013) E. M. Pridgen et al. Science Translational Medicine
- Effects of the Presence or Absence of a Protein Corona on Silica Nanoparticle Uptake and Impact on Cells
- (2012) Anna Lesniak et al. ACS Nano
- Cationic lipids activate intracellular signaling pathways
- (2012) Caroline Lonez et al. ADVANCED DRUG DELIVERY REVIEWS
- Surface Charge Switchable Nanoparticles Based on Zwitterionic Polymer for Enhanced Drug Delivery to Tumor
- (2012) You-Yong Yuan et al. ADVANCED MATERIALS
- Maximizing the Potency of siRNA Lipid Nanoparticles for Hepatic Gene Silencing In Vivo
- (2012) Muthusamy Jayaraman et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Nuclear-Targeted Drug Delivery of TAT Peptide-Conjugated Monodisperse Mesoporous Silica Nanoparticles
- (2012) Limin Pan et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Biomolecular coronas provide the biological identity of nanosized materials
- (2012) Marco P. Monopoli et al. Nature Nanotechnology
- Doxorubicin-Tethered Responsive Gold Nanoparticles Facilitate Intracellular Drug Delivery for Overcoming Multidrug Resistance in Cancer Cells
- (2011) Feng Wang et al. ACS Nano
- The effect of pH on PAMAM dendrimer–siRNA complexation — Endosomal considerations as determined by molecular dynamics simulation
- (2011) Defang Ouyang et al. BIOPHYSICAL CHEMISTRY
- FLT3 Ligand Enhances the Cancer Therapeutic Potency of Naked RNA Vaccines
- (2011) S. Kreiter et al. CANCER RESEARCH
- Understanding and controlling the interaction of nanomaterials with proteins in a physiological environment
- (2011) Carl D. Walkey et al. CHEMICAL SOCIETY REVIEWS
- Physical−Chemical Aspects of Protein Corona: Relevance toin Vitroandin VivoBiological Impacts of Nanoparticles
- (2011) Marco P. Monopoli et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Messenger RNA-based Vaccines With Dual Activity Induce Balanced TLR-7 Dependent Adaptive Immune Responses and Provide Antitumor Activity
- (2010) Mariola Fotin-Mleczek et al. JOURNAL OF IMMUNOTHERAPY
- Lipid-like materials for low-dose, in vivo gene silencing
- (2010) K. T. Love et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Internally Cationic Polyamidoamine PAMAM-OH Dendrimers for siRNA Delivery: Effect of the Degree of Quaternization and Cancer Targeting
- (2009) Mahesh L. Patil et al. BIOMACROMOLECULES
- Immunocompatibility properties of lipid–polymer hybrid nanoparticles with heterogeneous surface functional groups
- (2009) Carolina Salvador-Morales et al. BIOMATERIALS
- Nanocarriers’ entry into the cell: relevance to drug delivery
- (2009) Hervé Hillaireau et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Penetration and efficacy of VEGF siRNA using polyelectrolyte complex micelles in a human solid tumor model in-vitro
- (2009) Ahmed M. Al-Abd et al. JOURNAL OF CONTROLLED RELEASE
- Development of Lipidoid–siRNA Formulations for Systemic Delivery to the Liver
- (2009) Akin Akinc et al. MOLECULAR THERAPY
- Understanding biophysicochemical interactions at the nano–bio interface
- (2009) Andre E. Nel et al. NATURE MATERIALS
- Mechanism of active targeting in solid tumors with transferrin-containing gold nanoparticles
- (2009) C. H. J. Choi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Fast Release of Lipophilic Agents from Circulating PEG-PDLLA Micelles Revealed byin VivoFörster Resonance Energy Transfer Imaging
- (2008) Hongtao Chen et al. LANGMUIR
- Factors Affecting the Clearance and Biodistribution of Polymeric Nanoparticles
- (2008) Frank Alexis et al. MOLECULAR PHARMACEUTICS
- Surface-structure-regulated cell-membrane penetration by monolayer-protected nanoparticles
- (2008) Ayush Verma et al. NATURE MATERIALS
- The contribution of phagocytic activity of liver macrophages to the accelerated blood clearance (ABC) phenomenon of PEGylated liposomes in rats
- (2007) Tatsuhiro Ishida et al. JOURNAL OF CONTROLLED RELEASE
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