Apolipoprotein E Binding Drives Structural and Compositional Rearrangement of mRNA-Containing Lipid Nanoparticles

U1 snRNP regulates cancer cell migration and invasion in vitro

(2020) Jung-Min Oh et al.   Nature Communications

Opportunities and Challenges in the Delivery of mRNA-Based Vaccines

(2020) Abishek Wadhwa et al.   Pharmaceutics

Lipid nanoparticles for nucleic acid delivery: Current perspectives

(2020) Eleni Samaridou et al.   ADVANCED DRUG DELIVERY REVIEWS

The Biomolecular Corona of Lipid Nanoparticles for Gene Therapy

(2020) Valentina Francia et al.   BIOCONJUGATE CHEMISTRY

Linkage between endosomal escape of LNP-mRNA and loading into EVs for transport to other cells

(2019) Marco Maugeri et al.   Nature Communications

The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs

(2019) Akin Akinc et al.   Nature Nanotechnology

On the Formation and Morphology of Lipid Nanoparticles Containing Ionizable Cationic Lipids and siRNA

(2018) Jayesh A. Kulkarni et al.   ACS Nano

Perdeuteration of cholesterol for neutron scattering applications using recombinant Pichia pastoris

(2018) Martine Moulin et al.   CHEMISTRY AND PHYSICS OF LIPIDS

The impact of deuteration on natural and synthetic lipids: A neutron diffraction study

(2018) Alessandra Luchini et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

A Novel Amino Lipid Series for mRNA Delivery: Improved Endosomal Escape and Sustained Pharmacology and Safety in Non-human Primates

(2018) Staci Sabnis et al.   MOLECULAR THERAPY

Successful reprogramming of cellular protein production through mRNA delivered by functionalized lipid nanoparticles

(2018) Marianna Yanez Arteta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optimization of a Degradable Polymer–Lipid Nanoparticle for Potent Systemic Delivery of mRNA to the Lung Endothelium and Immune Cells

(2018) James C. Kaczmarek et al.   NANO LETTERS

Late Endosomal/Lysosomal Cholesterol Accumulation Is a Host Cell-Protective Mechanism Inhibiting Endosomal Escape of Influenza A Virus

(2018) Alexander Kühnl et al.   mBio

Quartz Crystal Microbalance Electronic Interfacing Systems: A Review

(2017) Abdulrahman Alassi et al.   SENSORS

Quantitative analysis of deuterium using the isotopic effect on quaternary 13C NMR chemical shifts

(2016) Tamim A. Darwish et al.   ANALYTICA CHIMICA ACTA

Small Angle X-ray and Neutron Scattering: Powerful Tools for Studying the Structure of Drug-Loaded Liposomes

(2016) Emanuela Di Cola et al.   Pharmaceutics

D38-cholesterol as a Raman active probe for imaging intracellular cholesterol storage

(2015) Alba Alfonso-García et al.   JOURNAL OF BIOMEDICAL OPTICS

The endosomal-lysosomal system: from acidification and cargo sorting to neurodegeneration

(2015) Yong-Bo Hu et al.   Translational Neurodegeneration

Phase diagram of a 4-component lipid mixture: DSPC/DOPC/POPC/chol

(2013) Tatyana M. Konyakhina et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Bilayer Thickness Mismatch Controls Domain Size in Model Membranes

(2013) Frederick A. Heberle et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Image-based analysis of lipid nanoparticle–mediated siRNA delivery, intracellular trafficking and endosomal escape

(2013) Jerome Gilleron et al.   NATURE BIOTECHNOLOGY

Influence of Polyethylene Glycol Lipid Desorption Rates on Pharmacokinetics and Pharmacodynamics of siRNA Lipid Nanoparticles

(2013) Barbara L Mui et al.   Molecular Therapy-Nucleic Acids

Maximizing the Potency of siRNA Lipid Nanoparticles for Hepatic Gene Silencing In Vivo

(2012) Muthusamy Jayaraman et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Spontaneous Formation of Two-Dimensional and Three-Dimensional Cholesterol Crystals in Single Hydrated Lipid Bilayers

(2012) Roy Ziblat et al.   BIOPHYSICAL JOURNAL

Effect of heavy water on phospholipid membranes: experimental confirmation of molecular dynamics simulations

(2012) Lenka Beranová et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Microfluidic Synthesis of Highly Potent Limit-size Lipid Nanoparticles for In Vivo Delivery of siRNA

(2012) Nathan M Belliveau et al.   Molecular Therapy-Nucleic Acids

Cholesterol-Dependent Macropinocytosis and Endosomal Escape Control the Transfection Efficiency of Lipoplexes in CHO Living Cells

(2011) Francesco Cardarelli et al.   MOLECULAR PHARMACEUTICS

Topology of human apolipoprotein E3 uniquely regulates its diverse biological functions

(2011) J. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeted Delivery of RNAi Therapeutics With Endogenous and Exogenous Ligand-Based Mechanisms

(2010) Akin Akinc et al.   MOLECULAR THERAPY

Rational design of cationic lipids for siRNA delivery

(2010) Sean C Semple et al.   NATURE BIOTECHNOLOGY

Apolipoprotein E: structure determines function, from atherosclerosis to Alzheimer's disease to AIDS

(2008) Robert W. Mahley et al.   JOURNAL OF LIPID RESEARCH

Duck Hepatitis B Virus Requires Cholesterol for Endosomal Escape during Virus Entry

(2008) A. Funk et al.   JOURNAL OF VIROLOGY

Floating Lipid Bilayers Deposited on Chemically Grafted Phosphatidylcholine Surfaces

(2008) Arwel V. Hughes et al.   LANGMUIR

NPC1/NPC2 function as a tag team duo to mobilize cholesterol

(2008) K. Subramanian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA