Towards Targeted Delivery Systems: Ligand Conjugation Strategies for mRNA Nanoparticle Tumor Vaccines

Aptamer Nanomedicine for Cancer Therapeutics: Barriers and Potential for Translation

(2015) Yeh-Hsing Lao et al.   ACS Nano

Structure–Function Assessment of Mannosylated Poly(β-amino esters) upon Targeted Antigen Presenting Cell Gene Delivery

(2015) Charles H. Jones et al.   BIOMACROMOLECULES

Structure of the Complex of F-Actin and DNGR-1, a C-Type Lectin Receptor Involved in Dendritic Cell Cross-Presentation of Dead Cell-Associated Antigens

(2015) Pavel Hanč et al.   IMMUNITY

Mannosylated Chitosan Nanoparticles Based Macrophage-Targeting Gene Delivery System Enhanced Cellular Uptake and Improved Transfection Efficiency

(2015) Yixing Peng et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

CD19-Targeted Nanodelivery of Doxorubicin Enhances Therapeutic Efficacy in B-Cell Acute Lymphoblastic Leukemia

(2015) Vinu Krishnan et al.   MOLECULAR PHARMACEUTICS

Targeting B16 tumorsin vivowith peptide-conjugated gold nanoparticles

(2015) Wilson Poon et al.   NANOTECHNOLOGY

BDCA3+CLEC9A+ human dendritic cell function and development

(2015) Evelyn van der Aa et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Synthesis of Fluorosurfactants for Emulsion-Based Biological Applications

(2014) Ya-Ling Chiu et al.   ACS Nano

Mannosylated solid lipid nanoparticles for lung-targeted delivery of Paclitaxel

(2014) Piyush Kumar Sahu et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

A Cationic Nanoemulsion for the Delivery of Next-generation RNA Vaccines

(2014) Luis A Brito et al.   MOLECULAR THERAPY

Aptamer-targeted Antigen Delivery

(2014) Brian C Wengerter et al.   MOLECULAR THERAPY

Messenger RNA (mRNA) nanoparticle tumour vaccination

(2014) Kyle K. L. Phua et al.   Nanoscale

Non-viral vectors for gene-based therapy

(2014) Hao Yin et al.   NATURE REVIEWS GENETICS

Intranasal mRNA nanoparticle vaccination induces prophylactic and therapeutic anti-tumor immunity

(2014) Kyle K. L. Phua et al.   Scientific Reports

Mannosylated Chitosan Nanoparticles for Delivery of Antisense Oligonucleotides for Macrophage Targeting

(2014) Gyati Shilakari Asthana et al.   Biomed Research International

Ligand-targeted particulate nanomedicines undergoing clinical evaluation: Current status

(2013) Roy van der Meel et al.   ADVANCED DRUG DELIVERY REVIEWS

Lipopolyplexes comprising imidazole/imidazolium lipophosphoramidate, histidinylated polyethyleneimine and siRNA as efficient formulation for siRNA transfection

(2013) Cristine Gonçalves et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Transfection efficiency and transgene expression kinetics of mRNA delivered in naked and nanoparticle format

(2013) Kyle K.L. Phua et al.   JOURNAL OF CONTROLLED RELEASE

Targeting of Autoantigens to DEC205+ Dendritic Cells In Vivo Suppresses Experimental Allergic Encephalomyelitis in Mice

(2013) S. Ring et al.   JOURNAL OF IMMUNOLOGY

Whole Blood Cells Loaded with Messenger RNA as an Anti-Tumor Vaccine

(2013) Kyle K. L. Phua et al.   Advanced Healthcare Materials

Liposomes as sterile preparations and limitations of sterilisation techniques in liposomal manufacturing

(2013) Ming-Ren Toh et al.   Asian Journal of Pharmaceutical Sciences

Cell surface binding and uptake of arginine- and lysine-rich penetratin peptides in absence and presence of proteoglycans

(2012) Helene L. Åmand et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The C-type lectin receptor CLEC9A mediates antigen uptake and (cross-)presentation by human blood BDCA3+ myeloid dendritic cells

(2012) G. Schreibelt et al.   BLOOD

Engineered peptides for the development of actively tumor targeted liposomal carriers of doxorubicin

(2012) Mostafa Shahin et al.   CANCER LETTERS

The Dendritic Cell Receptor Clec9A Binds Damaged Cells via Exposed Actin Filaments

(2012) Jian-Guo Zhang et al.   IMMUNITY

The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles

(2012) Eleonore Fröhlich   International Journal of Nanomedicine

The dendritic cell receptor DNGR-1 controls endocytic handling of necrotic cell antigens to favor cross-priming of CTLs in virus-infected mice

(2012) Santiago Zelenay et al.   JOURNAL OF CLINICAL INVESTIGATION

DEC-205 is a cell surface receptor for CpG oligonucleotides

(2012) M. H. Lahoud et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nonviral delivery of self-amplifying RNA vaccines

(2012) A. J. Geall et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mannosylated Dextran Nanoparticles: A pH-Sensitive System Engineered for Immunomodulation through Mannose Targeting

(2011) Lina Cui et al.   BIOCONJUGATE CHEMISTRY

The influence of PEG chain length and targeting moiety on antibody-mediated delivery of nanoparticle vaccines to human dendritic cells

(2011) Luis J. Cruz et al.   BIOMATERIALS

Synthesis and characterization of mannosylated pegylated polyethylenimine as a carrier for siRNA

(2011) NaJung Kim et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Enhancement of surface ligand display on PLGA nanoparticles with amphiphilic ligand conjugates

(2011) Jason Park et al.   JOURNAL OF CONTROLLED RELEASE

In Vitroandin VivomRNA Delivery Using Lipid-Enveloped pH-Responsive Polymer Nanoparticles

(2011) Xingfang Su et al.   MOLECULAR PHARMACEUTICS

Enhancement of dendritic cells transfection in vivo and of vaccination against B16F10 melanoma with mannosylated histidylated lipopolyplexes loaded with tumor antigen messenger RNA

(2011) Federico Perche et al.   Nanomedicine-Nanotechnology Biology and Medicine

Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A

(2011) J. Idoyaga et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeted antigen delivery and activation of dendritic cells in vivo: Steps towards cost effective vaccines

(2011) Paul J. Tacken et al.   SEMINARS IN IMMUNOLOGY

Delivery of siRNA Therapeutics: Barriers and Carriers

(2010) Jie Wang et al.   AAPS Journal

Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles

(2010) Chunbai He et al.   BIOMATERIALS

Intranodal Vaccination with Naked Antigen-Encoding RNA Elicits Potent Prophylactic and Therapeutic Antitumoral Immunity

(2010) S. Kreiter et al.   CANCER RESEARCH

Phosphorothioate cap analogs increase stability and translational efficiency of RNA vaccines in immature dendritic cells and induce superior immune responses in vivo

(2010) A N Kuhn et al.   GENE THERAPY

Lipid-mediated delivery of RNA is more efficient than delivery of DNA in non-dividing cells

(2010) S. Zou et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Delivery of messenger RNA using poly(ethylene imine)–poly(ethylene glycol)-copolymer blends for polyplex formation: Biophysical characterization and in vitro transfection properties

(2010) Heiko Debus et al.   JOURNAL OF CONTROLLED RELEASE

Selective gene delivery in dendritic cells with mannosylated and histidylated lipopolyplexes

(2010) Federico Perche et al.   JOURNAL OF DRUG TARGETING

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(2010) Jennifer Ziello et al.   MOLECULAR MEDICINE

Microbial immune evasion through exploitation of macrophage pattern-recognition receptors

(2009) George Hajishengallis et al.   CYTOKINE

CD205 (DEC-205): A recognition receptor for apoptotic and necrotic self

(2009) Rachel E. Shrimpton et al.   MOLECULAR IMMUNOLOGY

The role of phagosomal pH on the size-dependent efficiency of cross-presentation by dendritic cells

(2008) Kenny K. Tran et al.   BIOMATERIALS

The dendritic cell subtype-restricted C-type lectin Clec9A is a target for vaccine enhancement

(2008) I. Caminschi et al.   BLOOD

Inhibition of Melanoma Growth by Targeting of Antigen to Dendritic Cells via an Anti-DEC-205 Single-Chain Fragment Variable Molecule

(2008) T. S. Johnson et al.   CLINICAL CANCER RESEARCH

Mannosylated polyethylenimine coupled mesoporous silica nanoparticles for receptor-mediated gene delivery

(2008) In Young Park et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

The Role of Mannose Receptor in Allergen Recognition by Human Dendritic Cells (DC)

(2008) A GHAEMMAGHAMI et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Tumor therapy in mice via antigen targeting to a novel, DC-restricted C-type lectin

(2008) David Sancho et al.   JOURNAL OF CLINICAL INVESTIGATION

Single and Double Emulsion Manufacturing Techniques of an Amphiphilic Drug in PLGA Nanoparticles: Formulations of Mithramycin and Bioactivity

(2008) Einat Cohen-Sela et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Cell line-dependent internalization pathways and intracellular trafficking determine transfection efficiency of nanoparticle vectors

(2007) K DOUGLAS   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS