Nanoparticle designs for delivery of nucleic acid therapeutics as brain cancer therapies

Photocrosslinked Bioreducible Polymeric Nanoparticles for Enhanced Systemic siRNA Delivery as Cancer Therapy

(2021) Johan Karlsson et al.   ADVANCED FUNCTIONAL MATERIALS

A Virus‐Mimicking Nucleic Acid Nanogel Reprograms Microglia and Macrophages for Glioblastoma Therapy

(2021) Xihui Gao et al.   ADVANCED MATERIALS

A first-in-human phase 0 clinical study of RNA interference–based spherical nucleic acids in patients with recurrent glioblastoma

(2021) Priya Kumthekar et al.   Science Translational Medicine

Rethinking CRITID Procedure of Brain Targeting Drug Delivery: Circulation, Blood Brain Barrier Recognition, Intracellular Transport, Diseased Cell Targeting, Internalization, and Drug Release

(2021) Shaobo Ruan et al.   Advanced Science

Systemic Brain Delivery of Antisense Oligonucleotides across the Blood-Brain Barrier with a Glucose-Coated Polymeric Nanocarrier

(2020) Hyun Su Min et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Charge Conversional Biomimetic Nanocomplexes as a Multifunctional Platform for Boosting Orthotopic Glioblastoma RNAi Therapy

(2020) Yanjie Liu et al.   NANO LETTERS

Ionizable Lipid Nanoparticle-Mediated mRNA Delivery for Human CAR T Cell Engineering

(2020) Margaret M. Billingsley et al.   NANO LETTERS

EGFRvIII-CAR-T Cells with PD-1 Knockout Have Improved Anti-Glioma Activity

(2020) Haifeng Zhu et al.   PATHOLOGY & ONCOLOGY RESEARCH

Chlorotoxin-directed CAR T cells for specific and effective targeting of glioblastoma

(2020) Dongrui Wang et al.   Science Translational Medicine

Endo/Lysosome‐Escapable Delivery Depot for Improving BBB Transcytosis and Neuron Targeted Therapy of Alzheimer's Disease

(2020) Lulu Cai et al.   ADVANCED FUNCTIONAL MATERIALS

Single siRNA Nanocapsules for Effective siRNA Brain Delivery and Glioblastoma Treatment

(2020) Yan Zou et al.   ADVANCED MATERIALS

Combating Glioblastoma by Codelivering the Small-Molecule Inhibitor of STAT3 and STAT3siRNA with α5β1 Integrin Receptor-Selective Liposomes

(2020) Venugopal Vangala et al.   MOLECULAR PHARMACEUTICS

Efficiency of Cytosolic Delivery with Poly(β-amino ester) Nanoparticles is Dependent on the Effective pKa of the Polymer

(2020) Denis Routkevitch et al.   ACS Biomaterials-Science & Engineering

Poly(ethylene glycol)–Poly(beta-amino ester)-Based Nanoparticles for Suicide Gene Therapy Enhance Brain Penetration and Extend Survival in a Preclinical Human Glioblastoma Orthotopic Xenograft Model

(2020) Jayoung Kim et al.   ACS Biomaterials-Science & Engineering

Biomimetic anisotropic polymeric nanoparticles coated with red blood cell membranes for enhanced circulation and toxin removal

(2020) Elana Ben-Akiva et al.   Science Advances

Management of glioblastoma: State of the art and future directions

(2020) Aaron C. Tan et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Apoptin as a Tumor-Specific Therapeutic Agent: Current Perspective on Mechanism of Action and Delivery Systems

(2020) Waseem Akram Malla et al.   Frontiers in Cell and Developmental Biology

RNA Interference Nanotherapeutics for Treatment of Glioblastoma Multiforme

(2020) Prabhjeet Singh et al.   MOLECULAR PHARMACEUTICS

CD133 mRNA-Loaded Dendritic Cell Vaccination Abrogates Glioma Stem Cell Propagation in Humanized Glioblastoma Mouse Model

(2020) Angelique Sao-Mai Sy Do et al.   Molecular Therapy-Oncolytics

Engineering precision nanoparticles for drug delivery

(2020) Michael J. Mitchell et al.   NATURE REVIEWS DRUG DISCOVERY

In vitro-transcribed antigen receptor mRNA nanocarriers for transient expression in circulating T cells in vivo

(2020) N. N. Parayath et al.   Nature Communications

Viral Vectors as Gene Therapy Agents for Treatment of Glioblastoma

(2020) Oleg Mozhei et al.   Cancers

Delivery technologies for cancer immunotherapy

(2019) Rachel S. Riley et al.   NATURE REVIEWS DRUG DISCOVERY

High-Density Lipoprotein-Mimicking Nanodiscs for Chemo-immunotherapy against Glioblastoma Multiforme

(2019) Padma Kadiyala et al.   ACS Nano

Cancer-Targeting Nanoparticles for Combinatorial Nucleic Acid Delivery

(2019) Hannah J. Vaughan et al.   ADVANCED MATERIALS

Ligand‐Installed Nanocarriers toward Precision Therapy

(2019) Peng Mi et al.   ADVANCED MATERIALS

ROS‐Responsive Polymeric siRNA Nanomedicine Stabilized by Triple Interactions for the Robust Glioblastoma Combinational RNAi Therapy

(2019) Meng Zheng et al.   ADVANCED MATERIALS

Cancer-selective nanoparticles for combinatorial siRNA delivery to primary human GBM in vitro and in vivo

(2019) Kristen L. Kozielski et al.   BIOMATERIALS

Viral vector: potential therapeutic for glioblastoma multiforme

(2019) Ceera Manikandan et al.   CANCER GENE THERAPY

Glioblastoma-Associated Microglia Reprogramming Is Mediated by Functional Transfer of Extracellular miR-21

(2019) Erik R. Abels et al.   Cell Reports

Molecular targeted therapy of glioblastoma

(2019) Emilie Le Rhun et al.   CANCER TREATMENT REVIEWS

Shortened ex vivo manufacturing time of EGFRvIII-specific chimeric antigen receptor (CAR) T cells reduces immune exhaustion and enhances antiglioma therapeutic function

(2019) Hillary G. Caruso et al.   JOURNAL OF NEURO-ONCOLOGY

Carboxylated branched poly(β-amino ester) nanoparticles enable robust cytosolic protein delivery and CRISPR-Cas9 gene editing

(2019) Yuan Rui et al.   Science Advances

Evolution of Nanoparticle Protein Corona across the Blood–Brain Barrier

(2018) Alysia Cox et al.   ACS Nano

Traceable Nanoparticles with Dual Targeting and ROS Response for RNAi-Based Immunochemotherapy of Intracranial Glioblastoma Treatment

(2018) Chenmeng Qiao et al.   ADVANCED MATERIALS

Block Copolymer Micelles in Nanomedicine Applications

(2018) Horacio Cabral et al.   CHEMICAL REVIEWS

Electrostatically assembled dendrimer complex with a high-affinity protein binder for targeted gene delivery

(2018) Jong-won Kim et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Cationic polymers for non-viral gene delivery to human T cells

(2018) Brynn R. Olden et al.   JOURNAL OF CONTROLLED RELEASE

Bioreducible Polymeric Nanoparticles Containing Multiplexed Cancer Stem Cell Regulating miRNAs Inhibit Glioblastoma Growth and Prolong Survival

(2018) Hernando Lopez-Bertoni et al.   NANO LETTERS

Recurrent Glioblastoma Treated with Recombinant Poliovirus

(2018) Annick Desjardins et al.   NEW ENGLAND JOURNAL OF MEDICINE

Epidermal growth factor receptor and EGFRvIII in glioblastoma: signaling pathways and targeted therapies

(2018) Zhenyi An et al.   ONCOGENE

Nanotechnology-Based Strategies for siRNA Brain Delivery for Disease Therapy

(2018) Meng Zheng et al.   TRENDS IN BIOTECHNOLOGY

Biodegradable Polymeric Nanoparticles for Therapeutic Cancer Treatments

(2018) Johan Karlsson et al.   Annual Review of Chemical and Biomolecular Engineering

Enhanced efficacy of combined temozolomide and bromodomain inhibitor therapy for gliomas using targeted nanoparticles

(2018) Fred C. Lam et al.   Nature Communications

Spherical Nucleic Acid Architecture Can Improve the Efficacy of Polycation-Mediated siRNA Delivery

(2018) Jilian R. Melamed et al.   Molecular Therapy-Nucleic Acids

Polylysine-modified polyethylenimine polymer can generate genetically engineered mesenchymal stem cells for combinational suicidal gene therapy in glioblastoma

(2018) Yousra Saeed Malik et al.   Acta Biomaterialia

Liposomes and polymersomes: a comparative review towards cell mimicking

(2018) Emeline Rideau et al.   CHEMICAL SOCIETY REVIEWS

Polyethylenimine-Spherical Nucleic Acid Nanoparticles Against Gli1 Reduce the Chemoresistance and Stemness of Glioblastoma Cells

(2018) Jilian R. Melamed et al.   MOLECULAR PHARMACEUTICS

CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2011–2015

(2018) Quinn T Ostrom et al.   NEURO-ONCOLOGY

Vaccine-Based Immunotherapeutics for the Treatment of Glioblastoma: Advances, Challenges, and Future Perspectives

(2018) Joshua A. Cuoco et al.   World Neurosurgery

Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial

(2018) Derin B. Keskin et al.   NATURE

Effect of Tumor-Treating Fields Plus Maintenance Temozolomide vs Maintenance Temozolomide Alone on Survival in Patients With Glioblastoma

(2017) Roger Stupp et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Progress in brain targeting drug delivery system by nasal route

(2017) Abdur Rauf Khan et al.   JOURNAL OF CONTROLLED RELEASE

Solid lipid nanoparticles mediate non-viral delivery of plasmid DNA to dendritic cells

(2017) Alekhya Penumarthi et al.   JOURNAL OF NANOPARTICLE RESEARCH

Convection-enhanced delivery in glioblastoma: a review of preclinical and clinical studies

(2017) Arman Jahangiri et al.   JOURNAL OF NEUROSURGERY

Apoptin Gene Delivery by the Functionalized Polyamidoamine Dendrimer Derivatives Induces Cell Death of U87-MG Glioblastoma Cells

(2017) Yoonhee Bae et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Dendrimers as Nanocarriers for Nucleic Acid and Drug Delivery in Cancer Therapy

(2017) Livia Palmerston Mendes et al.   MOLECULES

In situ programming of leukaemia-specific T cells using synthetic DNA nanocarriers

(2017) Tyrel T. Smith et al.   Nature Nanotechnology

Molecular Subgroups of Glioblastoma– an Assessment by Immunohistochemical Markers

(2017) Ádám Nagy et al.   PATHOLOGY & ONCOLOGY RESEARCH

Multiplexed RNAi therapy against brain tumor-initiating cells via lipopolymeric nanoparticle infusion delays glioblastoma progression

(2017) Dou Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma

(2017) Donald M. O’Rourke et al.   Science Translational Medicine

Glycaemic control boosts glucosylated nanocarrier crossing the BBB into the brain

(2017) Y. Anraku et al.   Nature Communications

Cellular and Molecular Characterization of Microglia: A Unique Immune Cell Population

(2017) Carole Sousa et al.   Frontiers in Immunology

Sensitization of glioblastoma tumor micro-environment to chemo- and immunotherapy by Galectin-1 intranasal knock-down strategy

(2017) Matthias Van Woensel et al.   Scientific Reports

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

(2016) David N. Louis et al.   ACTA NEUROPATHOLOGICA

Chemical and structural modifications of RNAi therapeutics

(2016) Sook Hee Ku et al.   ADVANCED DRUG DELIVERY REVIEWS

The role of helper lipids in lipid nanoparticles (LNPs) designed for oligonucleotide delivery

(2016) Xinwei Cheng et al.   ADVANCED DRUG DELIVERY REVIEWS

PEGylation as a strategy for improving nanoparticle-based drug and gene delivery

(2016) Jung Soo Suk et al.   ADVANCED DRUG DELIVERY REVIEWS

Non-virally engineered human adipose mesenchymal stem cells produce BMP4, target brain tumors, and extend survival

(2016) Antonella Mangraviti et al.   BIOMATERIALS

Recent advances and future of immunotherapy for glioblastoma

(2016) Neha Kamran et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Dipeptide-functionalized polyamidoamine dendrimer-mediated apoptin gene delivery facilitates apoptosis of human primary glioma cells

(2016) Yoonhee Bae et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Glioblastoma multiforme targeted therapy: The Chlorotoxin story

(2016) Or Cohen-Inbar et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Development of siRNA-loaded chitosan nanoparticles targeting Galectin-1 for the treatment of glioblastoma multiforme via intranasal administration

(2016) Matthias Van Woensel et al.   JOURNAL OF CONTROLLED RELEASE

The effect of nanoparticle size on in vivo pharmacokinetics and cellular interaction

(2016) Nazanin Hoshyar et al.   Nanomedicine

From blood–brain barrier to blood–brain interface: new opportunities for CNS drug delivery

(2016) William A. Banks   NATURE REVIEWS DRUG DISCOVERY

Regression of Glioblastoma after Chimeric Antigen Receptor T-Cell Therapy

(2016) Christine E. Brown et al.   NEW ENGLAND JOURNAL OF MEDICINE

Nanoparticle engineered TRAIL-overexpressing adipose-derived stem cells target and eradicate glioblastoma via intracranial delivery

(2016) Xinyi Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hyaluronic acid-conjugated liposome nanoparticles for targeted delivery to CD44 overexpressing glioblastoma cells

(2016) Stephen L. Hayward et al.   Oncotarget

Localized RNAi Therapeutics of Chemoresistant Grade IV Glioma Using Hyaluronan-Grafted Lipid-Based Nanoparticles

(2015) Zvi R. Cohen et al.   ACS Nano

Polymeric Nanoparticles for Nonviral Gene Therapy Extend Brain Tumor Survival in Vivo

(2015) Antonella Mangraviti et al.   ACS Nano

Therapeutic applications of the cell-penetrating HIV-1 Tat peptide

(2015) Mafalda Rizzuti et al.   DRUG DISCOVERY TODAY

Structural and functional features of central nervous system lymphatic vessels

(2015) Antoine Louveau et al.   NATURE

Prospects of immune checkpoint modulators in the treatment of glioblastoma

(2015) Matthias Preusser et al.   Nature Reviews Neurology

Mesenchymal Progenitors Expressing TRAIL Induce Apoptosis in Sarcomas

(2015) Giulia Grisendi et al.   STEM CELLS

Advances and Challenges of Liposome Assisted Drug Delivery

(2015) Lisa Sercombe et al.   Frontiers in Pharmacology

Patient-derived glioblastoma stem cells are killed by CD133-specific CAR T cells but induce the T cell aging marker CD57

(2015) Xuekai Zhu et al.   Oncotarget

Bioreducible Cationic Polymer-Based Nanoparticles for Efficient and Environmentally Triggered Cytoplasmic siRNA Delivery to Primary Human Brain Cancer Cells

(2014) Kristen L. Kozielski et al.   ACS Nano

Biodegradable Polymeric Nanoparticles Show High Efficacy and Specificity at DNA Delivery to Human Glioblastoma in Vitro and in Vivo

(2014) Hugo Guerrero-Cázares et al.   ACS Nano

A Nanoparticle Carrying the p53 Gene Targets Tumors Including Cancer Stem Cells, Sensitizes Glioblastoma to Chemotherapy and Improves Survival

(2014) Sang-Soo Kim et al.   ACS Nano

Redox-Responsive Magnetic Nanoparticle for Targeted Convection-Enhanced Delivery of O6-Benzylguanine to Brain Tumors

(2014) Zachary R. Stephen et al.   ACS Nano

Retro-Inverso CendR Peptide-Mediated Polyethyleneimine for Intracranial Glioblastoma-Targeting Gene Therapy

(2014) Jing Wang et al.   BIOCONJUGATE CHEMISTRY

Therapeutic targeting of tumor-associated macrophages and microglia in glioblastoma

(2014) Robert L Bowman et al.   Immunotherapy

Emerging concepts in dendrimer-based nanomedicine: from design principles to clinical applications

(2014) R. M. Kannan et al.   JOURNAL OF INTERNAL MEDICINE

Endosomal Escape: A Bottleneck in Intracellular Delivery

(2014) Harshad K. Shete et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Prolongation of Life in Rats with Malignant Glioma by Intranasal siRNA/Drug Codelivery to the Brain with Cell-Penetrating Peptide-Modified Micelles

(2014) Takanori Kanazawa et al.   MOLECULAR PHARMACEUTICS

Multifunctional Cationic Lipid-Based Nanoparticles Facilitate Endosomal Escape and Reduction-Triggered Cytosolic siRNA Release

(2014) Maneesh Gujrati et al.   MOLECULAR PHARMACEUTICS

Intracellular delivery of nanomaterials: How to catch endosomal escape in the act

(2014) Thomas F. Martens et al.   Nano Today

A Randomized Trial of Bevacizumab for Newly Diagnosed Glioblastoma

(2014) Mark R. Gilbert et al.   NEW ENGLAND JOURNAL OF MEDICINE

Bevacizumab plus Radiotherapy–Temozolomide for Newly Diagnosed Glioblastoma

(2014) Olivier L. Chinot et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Future of Glioblastoma Therapy: Synergism of Standard of Care and Immunotherapy

(2014) Mira Patel et al.   Cancers

The Polyethyleneglycol Dilemma: Advantage and Disadvantage of PEGylation of Liposomes for Systemic Genes and Nucleic Acids Delivery to Tumors

(2013) Hiroto Hatakeyama et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Therapeutic vaccination against autologous cancer stem cells with mRNA-transfected dendritic cells in patients with glioblastoma

(2013) Einar Osland Vik-Mo et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Targeted gene delivery to glioblastoma using a C-end rule RGERPPR peptide-functionalised polyethylenimine complex

(2013) Jing Wang et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Comparison of Lentiviral and Sleeping Beauty Mediated αβ T Cell Receptor Gene Transfer

(2013) Anne-Christine Field et al.   PLoS One

Mechanism for the endocytosis of spherical nucleic acid nanoparticle conjugates

(2013) C. H. J. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Minimal "Self" Peptides That Inhibit Phagocytic Clearance and Enhance Delivery of Nanoparticles

(2013) P. L. Rodriguez et al.   SCIENCE

Spherical Nucleic Acid Nanoparticle Conjugates as an RNAi-Based Therapy for Glioblastoma

(2013) S. A. Jensen et al.   Science Translational Medicine

Tumor-targeted Chlorotoxin-coupled Nanoparticles for Nucleic Acid Delivery to Glioblastoma Cells: A Promising System for Glioblastoma Treatment

(2013) Pedro M Costa et al.   Molecular Therapy-Nucleic Acids

Novel crosslinking methods to design hydrogels

(2012) W.E. Hennink et al.   ADVANCED DRUG DELIVERY REVIEWS

Oncolytic Virus Therapy for Glioblastoma Multiforme

(2012) Guido Wollmann et al.   CANCER JOURNAL

Impact of extent of resection for recurrent glioblastoma on overall survival

(2012) Orin Bloch et al.   JOURNAL OF NEUROSURGERY

Synthetic nanoparticles functionalized with biomimetic leukocyte membranes possess cell-like functions

(2012) Alessandro Parodi et al.   Nature Nanotechnology

CD44 in human glioma correlates with histopathological grade and cell migration

(2012) Tsuneyasu Yoshida et al.   PATHOLOGY INTERNATIONAL

Polo-Like Kinase 1 Inhibition Kills Glioblastoma Multiforme Brain Tumor Cells in Part Through Loss of SOX2 and Delays Tumor Progression in Mice

(2012) Cathy Lee et al.   STEM CELLS

Modern methods for delivery of drugs across the blood–brain barrier

(2011) Yan Chen et al.   ADVANCED DRUG DELIVERY REVIEWS

Intranasal delivery of biologics to the central nervous system

(2011) Jeffrey J. Lochhead et al.   ADVANCED DRUG DELIVERY REVIEWS

Current concepts and management of glioblastoma

(2011) Matthias Preusser et al.   ANNALS OF NEUROLOGY

In Vivo Specific Delivery of c-Met siRNA to Glioblastoma Using Cationic Solid Lipid Nanoparticles

(2011) Juyoun Jin et al.   BIOCONJUGATE CHEMISTRY

Non-viral gene delivery nanoparticles based on Poly(β-amino esters) for treatment of glioblastoma

(2011) Stephany Y. Tzeng et al.   BIOMATERIALS

Multifunctional nanocarrier mediated co-delivery of doxorubicin and siRNA for synergistic enhancement of glioma apoptosis in rat

(2011) Du Cheng et al.   BIOMATERIALS

Cyclic RGD-Polyethylene Glycol-Polyethylenimine for Intracranial Glioblastoma-Targeted Gene Delivery

(2011) Changyou Zhan et al.   Chemistry-An Asian Journal

Novel cationic liposomes provide highly efficient delivery of DNA and RNA into dendritic cell progenitors and their immature offsets

(2011) Oleg O. Markov et al.   JOURNAL OF CONTROLLED RELEASE

Synergistic Induction of Apoptosis in Brain Cancer Cells by Targeted Codelivery of siRNA and Anticancer Drugs

(2011) Cheoljin Kim et al.   MOLECULAR PHARMACEUTICS

Chlorotoxin Labeled Magnetic Nanovectors for Targeted Gene Delivery to Glioma

(2010) Forrest M. Kievit et al.   ACS Nano

Targeted delivery of chlorotoxin-modified DNA-loaded nanoparticles to glioma via intravenous administration

(2010) Rongqin Huang et al.   BIOMATERIALS

RNA interference therapy for glioblastoma

(2010) Dongsheng Guo et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Radiation Dose–Volume Effects in the Brain

(2010) Yaacov Richard Lawrence et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Breaking down the barriers: siRNA delivery and endosome escape

(2010) M. Dominska et al.   JOURNAL OF CELL SCIENCE

Immunologic Escape After Prolonged Progression-Free Survival With Epidermal Growth Factor Receptor Variant III Peptide Vaccination in Patients With Newly Diagnosed Glioblastoma

(2010) John H. Sampson et al.   JOURNAL OF CLINICAL ONCOLOGY

Stealth nanoparticles: High density but sheddable PEG is a key for tumor targeting

(2010) Shyh-Dar Li et al.   JOURNAL OF CONTROLLED RELEASE

Cationic Amphiphile with Shikimic Acid Headgroup Shows More Systemic Promise Than Its Mannosyl Analogue as DNA Vaccine Carrier in Dendritic Cell Based Genetic Immunization

(2010) Ramishetti Srinivas et al.   JOURNAL OF MEDICINAL CHEMISTRY

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

(2010) Mark E. Davis et al.   NATURE

Ultralow-Fouling, Functionalizable, and Hydrolyzable Zwitterionic Materials and Their Derivatives for Biological Applications

(2009) Shaoyi Jiang et al.   ADVANCED MATERIALS

Selective Inhibition of Human Brain Tumor Cells through Multifunctional Quantum-Dot-Based siRNA Delivery

(2009) Jongjin Jung et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Vaccine therapy with dendritic cells transfected with Il13ra2 mRNA for glioma in mice

(2009) Makoto Saka et al.   JOURNAL OF NEUROSURGERY

Knocking down barriers: advances in siRNA delivery

(2009) Kathryn A. Whitehead et al.   NATURE REVIEWS DRUG DISCOVERY

Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapy

(2009) L. S. Sasportas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CNS Delivery Via Adsorptive Transcytosis

(2008) Françoise Hervé et al.   AAPS Journal

Synthesis and characterization of folate-PEG-grafted-hyperbranched-PEI for tumor-targeted gene delivery

(2008) Bing Liang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Biodistribution, Long-term Survival, and Safety of Human Adipose Tissue-derived Mesenchymal Stem Cells Transplanted in Nude Mice by High Sensitivity Non-invasive Bioluminescence Imaging

(2008) Marta Vilalta et al.   STEM CELLS AND DEVELOPMENT