Nucleoside-modified mRNA immunization elicits influenza virus hemagglutinin stalk-specific antibodies
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Title
Nucleoside-modified mRNA immunization elicits influenza virus hemagglutinin stalk-specific antibodies
Authors
Keywords
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Journal
Nature Communications
Volume 9, Issue 1, Pages -
Publisher
Springer Nature America, Inc
Online
2018-08-16
DOI
10.1038/s41467-018-05482-0
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Note: Only part of the references are listed.- mRNA vaccines — a new era in vaccinology
- (2018) Norbert Pardi et al. NATURE REVIEWS DRUG DISCOVERY
- Chimeric Hemagglutinin Constructs Induce Broad Protection against Influenza B Virus Challenge in the Mouse Model
- (2017) Megan E. Ermler et al. JOURNAL OF VIROLOGY
- Preclinical and Clinical Demonstration of Immunogenicity by mRNA Vaccines against H10N8 and H7N9 Influenza Viruses
- (2017) Kapil Bahl et al. MOLECULAR THERAPY
- Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination
- (2017) Norbert Pardi et al. NATURE
- Contemporary H3N2 influenza viruses have a glycosylation site that alters binding of antibodies elicited by egg-adapted vaccine strains
- (2017) Seth J. Zost et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Is It Possible to Develop a “Universal” Influenza Virus Vaccine?
- (2017) Sarah F. Andrews et al. Cold Spring Harbor Perspectives in Biology
- Is It Possible to Develop a “Universal” Influenza Virus Vaccine?
- (2017) Florian Krammer et al. Cold Spring Harbor Perspectives in Biology
- A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine
- (2017) Nicholas C. Wu et al. PLoS Pathogens
- Unmodified mRNA in LNPs constitutes a competitive technology for prophylactic vaccines
- (2017) Johannes Lutz et al. npj Vaccines
- A universal influenza virus vaccine candidate confers protection against pandemic H1N1 infection in preclinical ferret studies
- (2017) Raffael Nachbagauer et al. npj Vaccines
- Both Neutralizing and Non-Neutralizing Human H7N9 Influenza Vaccine-Induced Monoclonal Antibodies Confer Protection
- (2016) Carole J. Henry Dunand et al. Cell Host & Microbe
- Self-Amplifying mRNA Vaccines Expressing Multiple Conserved Influenza Antigens Confer Protection against Homologous and Heterosubtypic Viral Challenge
- (2016) Diletta Magini et al. PLoS One
- Dendrimer-RNA nanoparticles generate protective immunity against lethal Ebola, H1N1 influenza, andToxoplasma gondiichallenges with a single dose
- (2016) Jasdave S. Chahal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Optimal activation of Fc-mediated effector functions by influenza virus hemagglutinin antibodies requires two points of contact
- (2016) Paul E. Leon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Novel universal influenza virus vaccine approaches
- (2016) Florian Krammer Current Opinion in Virology
- Stalking influenza by vaccination with pre-fusion headless HA mini-stem
- (2016) Sophie A. Valkenburg et al. Scientific Reports
- Expression kinetics of nucleoside-modified mRNA delivered in lipid nanoparticles to mice by various routes
- (2015) Norbert Pardi et al. JOURNAL OF CONTROLLED RELEASE
- High-Affinity H7 Head and Stalk Domain–Specific Antibody Responses to an Inactivated Influenza H7N7 Vaccine After Priming With Live Attenuated Influenza Vaccine
- (2015) Jessica L. Halliley et al. JOURNAL OF INFECTIOUS DISEASES
- Induction of Broad-Based Immunity and Protective Efficacy by Self-amplifying mRNA Vaccines Encoding Influenza Virus Hemagglutinin
- (2015) Michela Brazzoli et al. JOURNAL OF VIROLOGY
- Sequence-engineered mRNA Without Chemical Nucleoside Modifications Enables an Effective Protein Therapy in Large Animals
- (2015) Andreas Thess et al. MOLECULAR THERAPY
- Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection
- (2015) Hadi M Yassine et al. NATURE MEDICINE
- Advances in the development of influenza virus vaccines
- (2015) Florian Krammer et al. NATURE REVIEWS DRUG DISCOVERY
- A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen
- (2015) A. Impagliazzo et al. SCIENCE
- A Live Attenuated Influenza A(H5N1) Vaccine Induces Long-Term Immunity in the Absence of a Primary Antibody Response
- (2014) Kawsar R. Talaat et al. JOURNAL OF INFECTIOUS DISEASES
- Broadly neutralizing hemagglutinin stalk–specific antibodies require FcγR interactions for protection against influenza virus in vivo
- (2014) David J DiLillo et al. NATURE MEDICINE
- Live attenuated H7N7 influenza vaccine primes for a vigorous antibody response to inactivated H7N7 influenza vaccine
- (2014) Tara M. Babu et al. VACCINE
- Immune history shapes specificity of pandemic H1N1 influenza antibody responses
- (2013) Yang Li et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Chimeric Hemagglutinin Influenza Virus Vaccine Constructs Elicit Broadly Protective Stalk-Specific Antibodies
- (2013) F. Krammer et al. JOURNAL OF VIROLOGY
- Biodegradable Lipids Enabling Rapidly Eliminated Lipid Nanoparticles for Systemic Delivery of RNAi Therapeutics
- (2013) Martin A Maier et al. MOLECULAR THERAPY
- Influenza virus hemagglutinin stalk-based antibodies and vaccines
- (2013) Florian Krammer et al. Current Opinion in Virology
- Expression of Functional Recombinant Hemagglutinin and Neuraminidase Proteins from the Novel H7N9 Influenza Virus Using the Baculovirus Expression System
- (2013) Irina Margine et al. Jove-Journal of Visualized Experiments
- Maximizing the Potency of siRNA Lipid Nanoparticles for Hepatic Gene Silencing In Vivo
- (2012) Muthusamy Jayaraman et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Influenza Viruses Expressing Chimeric Hemagglutinins: Globular Head and Stalk Domains Derived from Different Subtypes
- (2012) R. Hai et al. JOURNAL OF VIROLOGY
- Protective efficacy of in vitro synthesized, specific mRNA vaccines against influenza A virus infection
- (2012) Benjamin Petsch et al. NATURE BIOTECHNOLOGY
- A Carboxy-Terminal Trimerization Domain Stabilizes Conformational Epitopes on the Stalk Domain of Soluble Recombinant Hemagglutinin Substrates
- (2012) Florian Krammer et al. PLoS One
- Hemagglutinin stalk antibodies elicited by the 2009 pandemic influenza virus as a mechanism for the extinction of seasonal H1N1 viruses
- (2012) N. Pica et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Wide Prevalence of Heterosubtypic Broadly Neutralizing Human Anti-Influenza A Antibodies
- (2011) J. Sui et al. CLINICAL INFECTIOUS DISEASES
- Complement-Dependent Lysis of Influenza A Virus-Infected Cells by Broadly Cross-Reactive Human Monoclonal Antibodies
- (2011) M. Terajima et al. JOURNAL OF VIROLOGY
- Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA
- (2011) Katalin Karikó et al. NUCLEIC ACIDS RESEARCH
- Heterosubtypic neutralizing antibodies are produced by individuals immunized with a seasonal influenza vaccine
- (2010) Davide Corti et al. JOURNAL OF CLINICAL INVESTIGATION
- Structural Basis of Preexisting Immunity to the 2009 H1N1 Pandemic Influenza Virus
- (2010) R. Xu et al. SCIENCE
- Induction of Broadly Neutralizing H1N1 Influenza Antibodies by Vaccination
- (2010) C.-J. Wei et al. SCIENCE
- Incorporation of Pseudouridine Into mRNA Yields Superior Nonimmunogenic Vector With Increased Translational Capacity and Biological Stability
- (2008) Katalin Karikó et al. MOLECULAR THERAPY
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