Pre-adsorption of antibodies enables targeting of nanocarriers despite a biomolecular corona

Biological Identity of Nanoparticles In Vivo : Clinical Implications of the Protein Corona

(2017) Giulio Caracciolo et al.   TRENDS IN BIOTECHNOLOGY

Particle Targeting in Complex Biological Media

(2017) Qiong Dai et al.   Advanced Healthcare Materials

Improving Targeting of Metal–Phenolic Capsules by the Presence of Protein Coronas

(2016) Yi Ju et al.   ACS Applied Materials & Interfaces

Interleukin-2 Functionalized Nanocapsules for T Cell-Based Immunotherapy

(2016) Stefanie U. Frick et al.   ACS Nano

Impact of protein pre-coating on the protein corona composition and nanoparticle cellular uptake

(2016) Vahid Mirshafiee et al.   BIOMATERIALS

Antibody-targeted nanoparticles for cancer treatment

(2016) Thomas Carter et al.   Immunotherapy

Mapping of Molecular Structure of the Nanoscale Surface in Bionanoparticles

(2016) Luciana M. Herda et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Imaging of Polymeric Nanoparticles: Hard Challenge for Soft Objects

(2016) Patricia Renz et al.   MACROMOLECULAR CHEMISTRY AND PHYSICS

Protein source and choice of anticoagulant decisively affect nanoparticle protein corona and cellular uptake

(2016) S. Schöttler et al.   Nanoscale

Multifunctional clickable and protein-repellent magnetic silica nanoparticles

(2016) Diego Estupiñán et al.   Nanoscale

Complement proteins bind to nanoparticle protein corona and undergo dynamic exchange in vivo

(2016) Fangfang Chen et al.   Nature Nanotechnology

Protein adsorption is required for stealth effect of poly(ethylene glycol)- and poly(phosphoester)-coated nanocarriers

(2016) Susanne Schöttler et al.   Nature Nanotechnology

In situ characterization of nanoparticle biomolecular interactions in complex biological media by flow cytometry

(2016) Maria Cristina Lo Giudice et al.   Nature Communications

Monoclonal Antibody-Functionalized Multilayered Particles: Targeting Cancer Cells in the Presence of Protein Coronas

(2015) Qiong Dai et al.   ACS Nano

Colloidal Polymers with Controlled Sequence and Branching Constructed from Magnetic Field Assembled Nanoparticles

(2015) Markus B. Bannwarth et al.   ACS Nano

Acylsulfonamide-Functionalized Zwitterionic Gold Nanoparticles for Enhanced Cellular Uptake at Tumor pH

(2015) Tsukasa Mizuhara et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Carbohydrate-Based Nanocarriers Exhibiting Specific Cell Targeting with Minimum Influence from the Protein Corona

(2015) Biao Kang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Protein Corona of Nanoparticles: Distinct Proteins Regulate the Cellular Uptake

(2015) Sandra Ritz et al.   BIOMACROMOLECULES

Surface chemistry and serum type both determine the nanoparticle–protein corona

(2015) Daniela Pozzi et al.   Journal of Proteomics

Stealth Effect of Biomolecular Corona on Nanoparticle Uptake by Immune Cells

(2015) Giulio Caracciolo et al.   LANGMUIR

Principles of nanoparticle design for overcoming biological barriers to drug delivery

(2015) Elvin Blanco et al.   NATURE BIOTECHNOLOGY

Mapping protein binding sites on the biomolecular corona of nanoparticles

(2015) Philip M. Kelly et al.   Nature Nanotechnology

A holistic approach to targeting disease with polymeric nanoparticles

(2015) Christopher J. Cheng et al.   NATURE REVIEWS DRUG DISCOVERY

Targeting Ability of Affibody-Functionalized Particles Is Enhanced by Albumin but Inhibited by Serum Coronas

(2015) Qiong Dai et al.   ACS Macro Letters

Mass Spectrometry and Imaging Analysis of Nanoparticle-Containing Vesicles Provide a Mechanistic Insight into Cellular Trafficking

(2014) Daniel Hofmann et al.   ACS Nano

Secondary Structure of Corona Proteins Determines the Cell Surface Receptors Used by Nanoparticles

(2014) Candace C. Fleischer et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Diagnostic nanoparticle targeting of the EGF-receptor in complex biological conditions using single-domain antibodies

(2014) K. Zarschler et al.   Nanoscale

Effects of surface functionalization on the adsorption of human serum albumin onto nanoparticles – a fluorescence correlation spectroscopy study

(2014) Pauline Maffre et al.   Beilstein Journal of Nanotechnology

High-Throughput Biophysical Analysis of Protein Therapeutics to Examine Interrelationships Between Aggregate Formation and Conformational Stability

(2013) Rajoshi Chaudhuri et al.   AAPS Journal

Protein corona significantly reduces active targeting yield

(2013) Vahid Mirshafiee et al.   CHEMICAL COMMUNICATIONS

Targeting of Autoantigens to DEC205+ Dendritic Cells In Vivo Suppresses Experimental Allergic Encephalomyelitis in Mice

(2013) S. Ring et al.   JOURNAL OF IMMUNOLOGY

Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule corona adsorbs on the surface

(2013) Anna Salvati et al.   Nature Nanotechnology

Effects of subclass change on the structural stability of chimeric, humanized, and human antibodies under thermal stress

(2013) Takahiko Ito et al.   PROTEIN SCIENCE

Biomolecular coronas provide the biological identity of nanosized materials

(2012) Marco P. Monopoli et al.   Nature Nanotechnology

A review of protein adsorption on bioceramics

(2012) K. Wang et al.   Interface Focus

Taking Advantage of Unspecific Interactions to Produce Highly Active Magnetic Nanoparticle−Antibody Conjugates

(2011) Sara Puertas et al.   ACS Nano

Elucidation of Acid-induced Unfolding and Aggregation of Human Immunoglobulin IgG1 and IgG2 Fc

(2011) Ramil F. Latypov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adsorption of antibody onto Pluronic F68-covered nanoparticles: link with surface properties

(2011) Amelia Torcello-Gómez et al.   Soft Matter

Effects of Charge on Antibody Tissue Distribution and Pharmacokinetics

(2010) C. Andrew Boswell et al.   BIOCONJUGATE CHEMISTRY

Nanoparticle-induced unfolding of fibrinogen promotes Mac-1 receptor activation and inflammation

(2010) Zhou J. Deng et al.   Nature Nanotechnology