Delivery of modified mRNA to damaged myocardium by systemic administration of lipid nanoparticles
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Title
Delivery of modified mRNA to damaged myocardium by systemic administration of lipid nanoparticles
Authors
Keywords
Modified mRNA, Lipid nanoparticles, Myocardial infarction, Systemic delivery, Reperfusion injury
Journal
JOURNAL OF CONTROLLED RELEASE
Volume 343, Issue -, Pages 207-216
Publisher
Elsevier BV
Online
2022-01-22
DOI
10.1016/j.jconrel.2022.01.027
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- (2018) Fanfei Meng et al. ACS Nano
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- (2018) Kazutaka Miyamoto et al. Cell Stem Cell
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- (2018) Leif Carlsson et al. Molecular Therapy-Methods & Clinical Development
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- (2018) Ruchi Jain et al. Nucleic Acid Therapeutics
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- (2018) Ajit Magadum et al. MOLECULAR THERAPY
- Liposome encapsulated berberine treatment attenuates cardiac dysfunction after myocardial infarction
- (2017) Iris E. Allijn et al. JOURNAL OF CONTROLLED RELEASE
- 2017 ACC/AHA/HFSA Focused Update of the 2013 ACCF/AHA Guideline for the Management of Heart Failure
- (2017) Clyde W. Yancy et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Optimizing Cardiac Delivery of Modified mRNA
- (2017) Nishat Sultana et al. MOLECULAR THERAPY
- Barcoded nanoparticles for high throughput in vivo discovery of targeted therapeutics
- (2017) James E. Dahlman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Increased local delivery of antagomir therapeutics to the rodent myocardium using ultrasound and microbubbles
- (2016) Rick F.J. Kwekkeboom et al. JOURNAL OF CONTROLLED RELEASE
- Myocardial Delivery of Lipidoid Nanoparticle Carrying modRNA Induces Rapid and Transient Expression
- (2016) Irene C Turnbull et al. MOLECULAR THERAPY
- In vivocardiac reprogramming using an optimal single polycistronic construct: Figure 1
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- Expression kinetics of nucleoside-modified mRNA delivered in lipid nanoparticles to mice by various routes
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- Synthetic Chemically Modified mRNA-Based Delivery of Cytoprotective Factor Promotes Early Cardiomyocyte Survival Post-Acute Myocardial Infarction
- (2015) Chien-Ling Huang et al. MOLECULAR PHARMACEUTICS
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- (2015) Gabriele D’Uva et al. NATURE CELL BIOLOGY
- Cardiac-Specific YAP Activation Improves Cardiac Function and Survival in an Experimental Murine MI Model
- (2014) Zhiqiang Lin et al. CIRCULATION RESEARCH
- Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction
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- Mending broken hearts: cardiac development as a basis for adult heart regeneration and repair
- (2013) Mei Xin et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- A contemporary view on endothelial function in heart failure
- (2012) Eduard Shantsila et al. EUROPEAN JOURNAL OF HEART FAILURE
- Heart repair by reprogramming non-myocytes with cardiac transcription factors
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- In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes
- (2012) Li Qian et al. NATURE
- Biodistribution Studies of Nanoparticles Using Fluorescence Imaging: A Qualitative or Quantitative Method?
- (2012) Yang Liu et al. PHARMACEUTICAL RESEARCH
- YAP1, the nuclear target of Hippo signaling, stimulates heart growth through cardiomyocyte proliferation but not hypertrophy
- (2012) A. von Gise et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Heart regeneration
- (2011) Michael A. Laflamme et al. NATURE
- Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA
- (2011) Katalin Karikó et al. NUCLEIC ACIDS RESEARCH
- Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA
- (2010) Luigi Warren et al. Cell Stem Cell
- Neuregulin1/ErbB4 Signaling Induces Cardiomyocyte Proliferation and Repair of Heart Injury
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