Obstacles and opportunities in a forward vision for cancer nanomedicine

Differential Nanoparticle Sequestration by Macrophages and Scavenger Endothelial Cells Visualized in Vivo in Real-Time and at Ultrastructural Resolution

(2020) Yuya Hayashi et al.   ACS Nano

The entry of nanoparticles into solid tumours

(2020) Shrey Sindhwani et al.   NATURE MATERIALS

Tumor Targeting by αvβ3-Integrin-Specific Lipid Nanoparticles Occurs via Phagocyte Hitchhiking

(2020) Alexandros Marios Sofias et al.   ACS Nano

Multifunctional Bismuth Ferrite Nanocatalysts with Optical and Magnetic Functions for Ultrasound-Enhanced Tumor Theranostics

(2020) Lili Feng et al.   ACS Nano

Flow Rate Affects Nanoparticle Uptake into Endothelial Cells

(2020) Yih Yang Chen et al.   ADVANCED MATERIALS

Targeted camptothecin delivery via silicon nanoparticles reduces breast cancer metastasis

(2020) Marietta Landgraf et al.   BIOMATERIALS

A nanoparticle’s pathway into tumours

(2020) Irene de Lázaro et al.   NATURE MATERIALS

Nanoparticle interactions with immune cells dominate tumor retention and induce T cell–mediated tumor suppression in models of breast cancer

(2020) Preethi Korangath et al.   Science Advances

The dose threshold for nanoparticle tumour delivery

(2020) Ben Ouyang et al.   NATURE MATERIALS

Rapid, deep and precise profiling of the plasma proteome with multi-nanoparticle protein corona

(2020) John E. Blume et al.   Nature Communications

A reanalysis of nanoparticle tumor delivery using classical pharmacokinetic metrics

(2020) Lauren S. L. Price et al.   Science Advances

NIR-Triggered Phototherapy and Immunotherapy via an Antigen-Capturing Nanoplatform for Metastatic Cancer Treatment

(2019) Meng Wang et al.   Advanced Science

Use of Polymeric Nanoparticle Platform Targeting the Liver To Induce Treg-Mediated Antigen-Specific Immune Tolerance in a Pulmonary Allergen Sensitization Model

(2019) Qi Liu et al.   ACS Nano

Concepts of nanoparticle cellular uptake, intracellular trafficking, and kinetics in nanomedicine

(2019) Nathan D. Donahue et al.   ADVANCED DRUG DELIVERY REVIEWS

Colorectal tumor-on-a-chip system: A 3D tool for precision onco-nanomedicine

(2019) M. R. Carvalho et al.   Science Advances

Supervised Learning and Mass Spectrometry Predicts the in Vivo Fate of Nanomaterials

(2019) James Lazarovits et al.   ACS Nano

The beginning of the end of the nanomedicine hype

(2019) Kinam Park   JOURNAL OF CONTROLLED RELEASE

Precision Nanomedicine Development Based on Specific Opsonization of Human Cancer Patient-Personalized Protein Coronas

(2019) Jiayu Ren et al.   NANO LETTERS

On the issue of transparency and reproducibility in nanomedicine

(2019) Hon S. Leong et al.   Nature Nanotechnology

Survey of Clinical Translation of Cancer Nanomedicines—Lessons Learned from Successes and Failures

(2019) Hongliang He et al.   ACCOUNTS OF CHEMICAL RESEARCH

Comparison of conventional versus liposomal irinotecan in combination with fluorouracil for advanced pancreatic cancer: a single-institution experience

(2019) Justin C. Tossey et al.   MEDICAL ONCOLOGY

Smart cancer nanomedicine

(2019) Roy van der Meel et al.   Nature Nanotechnology

Directing Nanoparticle Biodistribution through Evasion and Exploitation of Stab2-Dependent Nanoparticle Uptake

(2018) Frederick Campbell et al.   ACS Nano

Efficacy and safety findings from DREAM: a phase III study of DHP107 (oral paclitaxel) versus IV paclitaxel in patients with advanced gastric cancer after failure of first-line chemotherapy

(2018) Y-K Kang et al.   ANNALS OF ONCOLOGY

A Direct Comparison of in Vitro and in Vivo Nucleic Acid Delivery Mediated by Hundreds of Nanoparticles Reveals a Weak Correlation

(2018) Kalina Paunovska et al.   NANO LETTERS

Rational Design of Mouse Models for Cancer Research

(2018) Marietta Landgraf et al.   TRENDS IN BIOTECHNOLOGY

TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy

(2018) Christopher B. Rodell et al.   Nature Biomedical Engineering

Minimum information reporting in bio–nano experimental literature

(2018) Matthew Faria et al.   Nature Nanotechnology

The Extracellular Matrix and Pancreatic Cancer: A Complex Relationship

(2018) Maximilian Weniger et al.   Cancers

Tumor-Vasculature-on-a-Chip for Investigating Nanoparticle Extravasation and Tumor Accumulation

(2018) Hao-Fei Wang et al.   ACS Nano

The Human In Vivo Biomolecule Corona onto PEGylated Liposomes: A Proof-of-Concept Clinical Study

(2018) Marilena Hadjidemetriou et al.   ADVANCED MATERIALS

Synthesis of Patient-Specific Nanomaterials

(2018) James Lazarovits et al.   NANO LETTERS

Talking the talk, but not walking the walk: RT-qPCR as a paradigm for the lack of reproducibility in molecular research

(2017) Stephen Bustin et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Tumor-penetrating peptide enhances transcytosis of silicasome-based chemotherapy for pancreatic cancer

(2017) Xiangsheng Liu et al.   JOURNAL OF CLINICAL INVESTIGATION

Antigen-capturing nanoparticles improve the abscopal effect and cancer immunotherapy

(2017) Yuanzeng Min et al.   Nature Nanotechnology

Toward a systematic exploration of nano-bio interactions

(2017) Xue Bai et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Designing nanomedicine for immuno-oncology

(2017) Wen Jiang et al.   Nature Biomedical Engineering

Complement proteins bind to nanoparticle protein corona and undergo dynamic exchange in vivo

(2016) Fangfang Chen et al.   Nature Nanotechnology

Theranostic barcoded nanoparticles for personalized cancer medicine

(2016) Zvi Yaari et al.   Nature Communications

Analysis of nanoparticle delivery to tumours

(2016) Stefan Wilhelm et al.   Nature Reviews Materials

Positron Emission Tomography Based Elucidation of the Enhanced Permeability and Retention Effect in Dogs with Cancer Using Copper-64 Liposomes

(2015) Anders E. Hansen et al.   ACS Nano

Neutrophil-Mediated Delivery of Therapeutic Nanoparticles across Blood Vessel Barrier for Treatment of Inflammation and Infection

(2015) Dafeng Chu et al.   ACS Nano

Nanoparticle–blood interactions: the implications on solid tumour targeting

(2015) James Lazarovits et al.   CHEMICAL COMMUNICATIONS

Overcoming the polyethylene glycol dilemma via pathological environment-sensitive change of the surface property of nanoparticles for cellular entry

(2015) Susumu Hama et al.   JOURNAL OF CONTROLLED RELEASE

Principles of nanoparticle design for overcoming biological barriers to drug delivery

(2015) Elvin Blanco et al.   NATURE BIOTECHNOLOGY

Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt(IV) pro-drug

(2015) Miles A. Miller et al.   Nature Communications

Efficacy and Cardiotoxicity of Liposomal Doxorubicin-Based Chemotherapy in Advanced Breast Cancer: A Meta-Analysis of Ten Randomized Controlled Trials

(2015) Meiyuan Xing et al.   PLoS One

Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles

(2014) Carl D. Walkey et al.   ACS Nano

EPR: Evidence and fallacy

(2014) Joseph W. Nichols et al.   JOURNAL OF CONTROLLED RELEASE

Monoclonal antibody-targeted, temperature-sensitive liposomes: In vivo tumor chemotherapeutics in combination with mild hyperthermia

(2014) Zahraa S. Al-Ahmady et al.   JOURNAL OF CONTROLLED RELEASE

Selective uptake of single-walled carbon nanotubes by circulating monocytes for enhanced tumour delivery

(2014) Bryan Ronain Smith et al.   Nature Nanotechnology

Two-Wave Nanotherapy To Target the Stroma and Optimize Gemcitabine Delivery To a Human Pancreatic Cancer Model in Mice

(2013) Huan Meng et al.   ACS Nano

Clinical Comparison between Paclitaxel Liposome (Lipusu®) and Paclitaxel for Treatment of Patients with Metastatic Gastric Cancer

(2013) Xu Xu et al.   Asian Pacific Journal of Cancer Prevention

Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule corona adsorbs on the surface

(2013) Anna Salvati et al.   Nature Nanotechnology

Increased Survival in Pancreatic Cancer with nab-Paclitaxel plus Gemcitabine

(2013) Daniel D. Von Hoff et al.   NEW ENGLAND JOURNAL OF MEDICINE

Tumour-on-a-chip provides an optical window into nanoparticle tissue transport

(2013) Alexandre Albanese et al.   Nature Communications

Blood–Nanoparticle Interactions and in Vivo Biodistribution: Impact of Surface PEG and Ligand Properties

(2012) Neha B. Shah et al.   MOLECULAR PHARMACEUTICS

Microparticles bearing encephalitogenic peptides induce T-cell tolerance and ameliorate experimental autoimmune encephalomyelitis

(2012) Daniel R Getts et al.   NATURE BIOTECHNOLOGY

Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner

(2012) Vikash P. Chauhan et al.   Nature Nanotechnology

Nanoparticle-mediated codelivery of myelin antigen and a tolerogenic small molecule suppresses experimental autoimmune encephalomyelitis

(2012) A. Yeste et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fluorescent Nanorods and Nanospheres for Real-Time In Vivo Probing of Nanoparticle Shape-Dependent Tumor Penetration

(2011) Vikash P. Chauhan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tumour necrosis factor-alpha increases extravasation of virus particles into tumour tissue by activating the Rho A/Rho kinase pathway

(2011) Takahiro Seki et al.   JOURNAL OF CONTROLLED RELEASE

Diffusion of Particles in the Extracellular Matrix: The Effect of Repulsive Electrostatic Interactions

(2010) Triantafyllos Stylianopoulos et al.   BIOPHYSICAL JOURNAL

The Effects of Particle Size and Molecular Targeting on the Intratumoral and Subcellular Distribution of Polymeric Nanoparticles

(2010) Helen Lee et al.   MOLECULAR PHARMACEUTICS

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

(2010) Mark E. Davis et al.   NATURE

Biodistribution of gold nanoparticles and gene expression changes in the liver and spleen after intravenous administration in rats

(2009) Suresh K. Balasubramanian et al.   BIOMATERIALS