Arginine-Rich Peptide-Based mRNA Nanocomplexes Efficiently Instigate Cytotoxic T Cell Immunity Dependent on the Amphipathic Organization of the Peptide

Type I Interferons Modulate CD8 + T Cell Immunity to mRNA Vaccines

(2017) Ans De Beuckelaer et al.   TRENDS IN MOLECULAR MEDICINE

Type I Interferons Interfere with the Capacity of mRNA Lipoplex Vaccines to Elicit Cytolytic T Cell Responses

(2016) Ans De Beuckelaer et al.   MOLECULAR THERAPY

Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy

(2016) Lena M. Kranz et al.   NATURE

Reversible Activation of a Cell-Penetrating Peptide in a Membrane Environment

(2015) Denise K. Schach et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Intranodal vaccination with mRNA-optimized dendritic cells in metastatic melanoma patients

(2015) Kalijn F Bol et al.   OncoImmunology

Self-adjuvanted mRNA vaccination in advanced prostate cancer patients: a first-in-man phase I/IIa study

(2015) Hubert Kübler et al.   Journal for ImmunoTherapy of Cancer

Cell-Penetrating Peptides: Design, Synthesis, and Applications

(2014) Dana Maria Copolovici et al.   ACS Nano

The ReNAissanCe of mRNA-based cancer therapy

(2014) Sandra Van Lint et al.   Expert Review of Vaccines

Development and characterization of self-assembling nanoparticles using a bio-inspired amphipathic peptide for gene delivery

(2014) Helen O. McCarthy et al.   JOURNAL OF CONTROLLED RELEASE

mRNA-based therapeutics — developing a new class of drugs

(2014) Ugur Sahin et al.   NATURE REVIEWS DRUG DISCOVERY

Molecular Parameters of siRNA–Cell Penetrating Peptide Nanocomplexes for Efficient Cellular Delivery

(2013) Alexander H. van Asbeck et al.   ACS Nano

RNA-Based Vaccination: Sending a Strong Message

(2013) David B. Weiner   MOLECULAR THERAPY

mRNA

(2013) Sandra Van Lint et al.   Human Vaccines & Immunotherapeutics

Preclinical Evaluation of TriMix and Antigen mRNA-Based Antitumor Therapy

(2012) S. Van Lint et al.   CANCER RESEARCH

Type I IFN Counteracts the Induction of Antigen-Specific Immune Responses by Lipid-Based Delivery of mRNA Vaccines

(2012) Charlotte Pollard et al.   MOLECULAR THERAPY

Self-Assembling Peptide-Based Nanoparticles for siRNA Delivery in Primary Cell Lines

(2012) Sébastien Deshayes et al.   Small

mRNA: delivering an antitumor message?

(2011) Sandra Van Lint et al.   Immunotherapy

Messenger RNA-based Vaccines With Dual Activity Induce Balanced TLR-7 Dependent Adaptive Immune Responses and Provide Antitumor Activity

(2010) Mariola Fotin-Mleczek et al.   JOURNAL OF IMMUNOTHERAPY

Intradermal Vaccinations With RNA Coding for TAA Generate CD8+ and CD4+ Immune Responses and Induce Clinical Benefit in Vaccinated Patients

(2010) Susanne M Rittig et al.   MOLECULAR THERAPY

Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activation

(2010) Bart R. Anderson et al.   NUCLEIC ACIDS RESEARCH

Novel Reporter Mouse Reveals Constitutive and Inflammatory Expression of IFN-  In Vivo

(2009) S. Lienenklaus et al.   JOURNAL OF IMMUNOLOGY

Incorporation of Pseudouridine Into mRNA Yields Superior Nonimmunogenic Vector With Increased Translational Capacity and Biological Stability

(2008) Katalin Karikó et al.   MOLECULAR THERAPY