标题
Aging of mesenchymal stem cell: machinery, markers, and strategies of fighting
作者
关键词
-
出版物
CELLULAR & MOLECULAR BIOLOGY LETTERS
Volume 27, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2022-08-19
DOI
10.1186/s11658-022-00366-0
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- NAP1L2 drives mesenchymal stem cell senescence and suppresses osteogenic differentiation
- (2022) Meilin Hu et al. AGING CELL
- AMPK and the Adaptation to Exercise
- (2022) Hannah R. Spaulding et al. Annual Review of Physiology
- Systems approaches to investigate the role of NF-κB signaling in aging
- (2022) Masatoshi Haga et al. BIOCHEMICAL JOURNAL
- Specificity of H2O2 signaling in leaf senescence: is the ratio of H2O2 contents in different cellular compartments sensed in Arabidopsis plants?
- (2022) Ulrike Zentgraf et al. CELLULAR & MOLECULAR BIOLOGY LETTERS
- Targeting cellular senescence with senotherapeutics: senolytics and senomorphics
- (2022) Lei Zhang et al. FEBS Journal
- Long Non-Coding RNA KCNQ1OT1 Regulates Protein Kinase CK2 Via miR-760 in Senescence and Calorie Restriction
- (2022) Yoonsung Lee et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Resveratrol inhibits the progression of premature senescence partially by regulating v-rel avian reticuloendotheliosis viral oncogene homolog A (RELA) and sirtuin 1 (SIRT1)
- (2022) Shuangjun He et al. RENAL FAILURE
- Superoxide dismutase and catalase significantly improve the osteogenic differentiation potential of osteogenetically compromised human adipose tissue-derived stromal cells in vitro
- (2022) Benita Sahlender et al. Stem Cell Research
- Targeting aging mechanisms: pharmacological perspectives
- (2022) Alexey Moskalev et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Application and mechanism of probiotics in skin care: A review
- (2022) Jinyan Yu et al. Journal of Cosmetic Dermatology
- The transplantation of rapamycin-treated senescent human mesenchymal stem cells with enhanced proangiogenic activity promotes neovascularization and ischemic limb salvage in mice
- (2022) Yu-lin Cao et al. ACTA PHARMACOLOGICA SINICA
- Oxysterols are potential physiological regulators of ageing
- (2022) Philippe de Medina et al. AGEING RESEARCH REVIEWS
- Contribution of proteases to the hallmarks of aging and to age‐related neurodegeneration
- (2022) Mamta Rai et al. AGING CELL
- Cellular Senescence: Molecular Targets, Biomarkers, and Senolytic Drugs
- (2022) Natalie Kudlova et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Senolytic drugs: Beyond the promise and the hype
- (2022) Diana Jurk et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Vegetables and Their Bioactive Compounds as Anti-Aging Drugs
- (2022) Hamza Mechchate et al. MOLECULES
- Mesenchymal Stem/Stromal Cell Senescence: Hallmarks, Mechanisms, and Combating Strategies
- (2022) Zhijie Weng et al. Stem Cells Translational Medicine
- Editorial: Cellular Senescence and Cellular Communications Within Tissue Microenvironments During Aging
- (2022) Ziyu Wei et al. Frontiers in Physiology
- Dietary Supplements and Natural Products: An Update on Their Clinical Effectiveness and Molecular Mechanisms of Action During Accelerated Biological Aging
- (2022) Ye Chen et al. Frontiers in Genetics
- Enriched Environment and Exercise Enhance Stem Cell Therapy for Stroke, Parkinson’s Disease, and Huntington’s Disease
- (2022) Reed Berlet et al. Frontiers in Cell and Developmental Biology
- Ovariectomy reduces the cardiac cytoprotection in rats exposed to particulate air pollutant
- (2021) Lílian Corrêa Costa-Beber et al. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
- Epigenetics of Aging and Aging-Associated Diseases
- (2021) Dominik Saul et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Aging and age‐related diseases: from mechanisms to therapeutic strategies
- (2021) Zhe Li et al. BIOGERONTOLOGY
- An Intermediate Concentration of Calcium with Antioxidant Supplement in Culture Medium Enhances Proliferation and Decreases the Aging of Bone Marrow Mesenchymal Stem Cells
- (2021) Chung-Da Yang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- National Institute on Aging Workshop: Repurposing Drugs or Dietary Supplements for Their Senolytic or Senomorphic Effects: Considerations for Clinical Trials
- (2021) Sergei Romashkan et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Dietary Anti-Aging Polyphenols and Potential Mechanisms
- (2021) Jing Luo et al. Antioxidants
- NAD + supplementation prevents STING‐induced senescence in ataxia telangiectasia by improving mitophagy
- (2021) Beimeng Yang et al. AGING CELL
- Effects of exercise on cellular and tissue aging
- (2021) Priscila Viana Carapeto et al. Aging-US
- The effects of metformin on autophagy
- (2021) Guangli Lu et al. BIOMEDICINE & PHARMACOTHERAPY
- Different Stages of Quiescence, Senescence, and Cell Stress Identified by Molecular Algorithm Based on the Expression of Ki67, RPS6, and Beta-Galactosidase Activity
- (2021) Nicola Alessio et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- p16-3MR: A Novel Model to Study Cellular Senescence in Cigarette Smoke-Induced Lung Injuries
- (2021) Gagandeep Kaur et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Non-Coding RNAs Steering the Senescence-Related Progress, Properties, and Application of Mesenchymal Stem Cells
- (2021) Jingyi Cai et al. Frontiers in Cell and Developmental Biology
- Exercise reduces circulating biomarkers of cellular senescence in humans
- (2021) Davis A. Englund et al. AGING CELL
- Transfection of STAT3 overexpression plasmid mediated through recombinant lentivirus promotes differentiation of bone marrow mesenchymal stem cells into neural cells in fetal rats with spina bifida aperta
- (2021) Mingyu Jiang et al. Aging-US
- Assessment of Long-Term in vitro Multiplied Human Wharton’s Jelly-Derived Mesenchymal Stem Cells prior to Their Use in Clinical Administration
- (2021) Urvi Panwar et al. CELLS TISSUES ORGANS
- LncRNA DNM3OS regulates GREM2 via miR-127-5p to suppress early chondrogenic differentiation of rat mesenchymal stem cells under hypoxic conditions
- (2021) Xiaozhong Zhou et al. CELLULAR & MOLECULAR BIOLOGY LETTERS
- The effect of vitamin D supplementation on circulating osteoprogenitor cells: A pilot randomized controlled trial
- (2021) Jack Feehan et al. EXPERIMENTAL GERONTOLOGY
- Methylsulfonylmethane enhances MSC chondrogenic commitment and promotes pre-osteoblasts formation
- (2021) Luca Dalle Carbonare et al. Stem Cell Research & Therapy
- LRRc17 controls BMSC senescence via mitophagy and inhibits the therapeutic effect of BMSCs on ovariectomy-induced bone loss
- (2021) Fei Liu et al. Redox Biology
- Protective Mechanism of Humanin Against Oxidative Stress in Aging-Related Cardiovascular Diseases
- (2021) He Cai et al. Frontiers in Endocrinology
- Natural Compounds and PCL Nanofibers: A Novel Tool to Counteract Stem Cell Senescence
- (2021) Emanuela Bellu et al. Cells
- Supplemental Ferulic Acid Inhibits Total Body Irradiation-Mediated Bone Marrow Damage, Bone Mass Loss, Stem Cell Senescence, and Hematopoietic Defect in Mice by Enhancing Antioxidant Defense Systems
- (2021) Sajeev Wagle et al. Antioxidants
- Senolytics improve bone forming potential of bone marrow mesenchymal stem cells from aged mice
- (2021) Yueying Zhou et al. npj Regenerative Medicine
- A Senescence Bystander Effect in Human Lung Fibroblasts
- (2021) David W. Waters et al. Biomedicines
- Immunosenescence and inflammaging in the aging process: age-related diseases or longevity?
- (2021) Aurelia Santoro et al. AGEING RESEARCH REVIEWS
- Stress and telomere shortening: Insights from cellular mechanisms
- (2021) Jue Lin et al. AGEING RESEARCH REVIEWS
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- (2021) Paweł Uruski et al. CELLULAR & MOLECULAR BIOLOGY LETTERS
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- (2021) Xiao-Yu He et al. CELLULAR & MOLECULAR BIOLOGY LETTERS
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- (2021) Xiaoxia Su et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
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- (2021) Brendan Zotter et al. JOURNAL OF NEUROSCIENCE
- Strategies for late phase preclinical and early clinical trials of senolytics
- (2021) Erin O. Wissler Gerdes et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Proteomic and Biological Analysis of the Effects of Metformin Senomorphics on the Mesenchymal Stromal Cells
- (2021) Mustafa Burak Acar et al. Frontiers in Bioengineering and Biotechnology
- Effects of poor sleep on the immune cell landscape as assessed by single-cell analysis
- (2021) Xiuxing Liu et al. Communications Biology
- TL1A/TNFR2‐mediated mitochondrial dysfunction of fibroblast‐like synoviocytes increases inflammatory response in patients with rheumatoid arthritis via reactive oxygen species generation
- (2020) Mahmoud Al‐Azab et al. FEBS Journal
- Exercise enhances skeletal muscle regeneration by promoting senescence in fibro-adipogenic progenitors
- (2020) Yuki Saito et al. Nature Communications
- miR‐155‐5p inhibition rejuvenates aged mesenchymal stem cells and enhances cardioprotection following infarction
- (2020) Yimei Hong et al. AGING CELL
- Indian Hedgehog regulates senescence in bone marrow-derived mesenchymal stem cell through modulation of ROS/mTOR/4EBP1, p70S6K1/2 pathway
- (2020) Mahmoud Al-Azab et al. Aging-US
- Benefits of Metformin in Attenuating the Hallmarks of Aging
- (2020) Ameya S. Kulkarni et al. Cell Metabolism
- TGF-β-driven downregulation of the Wnt/β-Catenin transcription factor TCF7L2/TCF4 in PDGFRα+ fibroblasts
- (2020) Osvaldo Contreras et al. JOURNAL OF CELL SCIENCE
- Cytoprotective effects of antioxidant supplementation on mesenchymal stem cell therapy
- (2020) Mohammad Panahi et al. JOURNAL OF CELLULAR PHYSIOLOGY
- JAK2/STAT3 regulates estrogen-related senescence of bone marrow stem cells
- (2020) Wenjing Wu et al. JOURNAL OF ENDOCRINOLOGY
- SIRT1 and aging related signaling pathways
- (2020) Cui Chen et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Exosomes: Multifaceted Messengers in Atherosclerosis
- (2020) Hongyun Wang et al. Current Atherosclerosis Reports
- Senolytic drugs: from discovery to translation
- (2020) J. L. Kirkland et al. JOURNAL OF INTERNAL MEDICINE
- Hepatocyte growth factor (HGF) and stem cell factor (SCF) maintained the stemness of human bone marrow mesenchymal stem cells (hBMSCs) during long-term expansion by preserving mitochondrial function via the PI3K/AKT, ERK1/2, and STAT3 signaling pathways
- (2020) Zeyuan Cao et al. Stem Cell Research & Therapy
- Mesenchymal stem cell-derived extracellular vesicle-based therapies protect against coupled degeneration of the central nervous and vascular systems in stroke
- (2020) Abolfazl Rahmani et al. AGEING RESEARCH REVIEWS
- Senolytic Drugs: Reducing Senescent Cell Viability to Extend Health Span
- (2020) Paul D. Robbins et al. Annual Review of Pharmacology and Toxicology
- The role of mitochondrial dysfunction in mesenchymal stem cell senescence
- (2020) Yibo Wang et al. CELL AND TISSUE RESEARCH
- Calorie restriction delays cardiac senescence and improves cardiac function in obese diabetic rats
- (2020) Naoki Makino et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Targeting STAT3 in Cancer Immunotherapy
- (2020) Sailan Zou et al. Molecular Cancer
- Mechanisms of Aging and the Preventive Effects of Resveratrol on Age-Related Diseases
- (2020) In Soo Pyo et al. MOLECULES
- Shortened telomere length in peripheral blood leukocytes of patients with lung cancer, chronic obstructive pulmonary disease in a high indoor air pollution region in China
- (2020) Yanfeng Xue et al. MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
- Oxidative stress-mediated mitochondrial dysfunction facilitates mesenchymal stem cell senescence in ankylosing spondylitis
- (2020) Guiwen Ye et al. Cell Death & Disease
- Effect of rapamycin on aging and age-related diseases—past and future
- (2020) Ramasamy Selvarani et al. GeroScience
- MicroRNAs are critical regulators of senescence and aging in mesenchymal stem cells
- (2020) Matthew L. Potter et al. BONE
- Potential Anti-Aging Substances Derived from Seaweeds
- (2020) Lei Cao et al. Marine Drugs
- Mitochondria and cellular redox state on the route from ageing to Alzheimer’s disease
- (2020) G. Abate et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Cellular senescence in ageing: from mechanisms to therapeutic opportunities
- (2020) Raffaella Di Micco et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Creatine Alleviates Doxorubicin-Induced Liver Damage by Inhibiting Liver Fibrosis, Inflammation, Oxidative Stress, and Cellular Senescence
- (2020) Nouf Aljobaily et al. Nutrients
- The Senescence-Associated Secretory Phenotype (SASP) in the Challenging Future of Cancer Therapy and Age-Related Diseases
- (2020) Lorenzo Cuollo et al. Biology-Basel
- Recent advances in the field of caloric restriction mimetics and anti-aging molecules
- (2020) Jan Martel et al. AGEING RESEARCH REVIEWS
- Calorie Restriction as a New Treatment of Inflammatory Diseases
- (2020) Tunay Kökten et al. Advances in Nutrition
- Changes in Stemness Properties, Differentiation Potential, Oxidative Stress, Senescence and Mitochondrial Function in Wharton’s Jelly Stem Cells of Umbilical Cords of Mothers with Gestational Diabetes Mellitus
- (2019) Chiou-Mee Kong et al. Stem Cell Reviews and Reports
- Melatonin plays critical role in mesenchymal stem cell-based regenerative medicine in vitro and in vivo
- (2019) Chenxia Hu et al. Stem Cell Research & Therapy
- Individual response to mTOR inhibition in delaying replicative senescence of mesenchymal stromal cells
- (2019) Eliane Antonioli et al. PLoS One
- Combating osteoporosis and obesity with exercise: leveraging cell mechanosensitivity
- (2019) Gabriel M. Pagnotti et al. Nature Reviews Endocrinology
- Chondrogenic differentiation of bone marrow-derived mesenchymal stem cells following transfection with Indian hedgehog and sonic hedgehog using a rotary cell culture system
- (2019) Liyang Chen et al. CELLULAR & MOLECULAR BIOLOGY LETTERS
- Fine air pollution particles induce endothelial senescence via redox-sensitive activation of local angiotensin system
- (2019) Kushal Sharma et al. ENVIRONMENTAL POLLUTION
- Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data
- (2019) Yang'ou Wu et al. GENE
- An Endogenous Anti-aging Factor, Sonic Hedgehog, Suppresses Endometrial Stem Cell Aging through SERPINB2
- (2019) Ara Cho et al. MOLECULAR THERAPY
- Acceleration of β Cell Aging Determines Diabetes and Senolysis Improves Disease Outcomes
- (2019) Cristina Aguayo-Mazzucato et al. Cell Metabolism
- The role of different SIRT1-mediated signaling pathways in toxic injury
- (2019) Zhihua Ren et al. CELLULAR & MOLECULAR BIOLOGY LETTERS
- Delayed sleep-onset and biological age: late sleep-onset is associated with shorter telomere length
- (2019) Dora Wynchank et al. SLEEP
- Particulate matter-induced senescence of skin keratinocytes involves oxidative stress-dependent epigenetic modifications
- (2019) Yea Seong Ryu et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- Curcumin: Biological, Pharmaceutical, Nutraceutical, and Analytical Aspects
- (2019) Raghavendhar R. Kotha et al. MOLECULES
- Targeting senescence improves angiogenic potential of adipose-derived mesenchymal stem cells in patients with preeclampsia
- (2019) Sonja Suvakov et al. Biology of Sex Differences
- Nicotinamide mononucleotide (NMN) supplementation promotes anti-aging miRNA expression profile in the aorta of aged mice, predicting epigenetic rejuvenation and anti-atherogenic effects
- (2019) Tamas Kiss et al. GeroScience
- A discovery platform for the identification of caloric restriction mimetics with broad health-improving effects
- (2019) Oliver Kepp et al. Autophagy
- Caloric restriction maintains stem cells through niche and regulates stem cell aging
- (2019) Nagarajan Maharajan et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Current nutritional and pharmacological anti-aging interventions
- (2019) Manuel Ros et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Personal exposure to NO2 and benzene in the Cape Town region of South Africa is associated with shorter leukocyte telomere length in women
- (2019) Frans Everson et al. ENVIRONMENTAL RESEARCH
- Factors that affect the translation of dietary restriction into a longer life
- (2019) Jakob Frieling et al. IUBMB LIFE
- Active vitamin D supplementation alleviates initiation and progression of nonalcoholic fatty liver disease by repressing the p53 pathway
- (2019) Yuanyuan Liu et al. LIFE SCIENCES
- Probiotic bacteria as modulators of cellular senescence: emerging concepts and opportunities
- (2019) Rohit Sharma et al. Gut Microbes
- Anti-senescence compounds: A potential nutraceutical approach to healthy aging
- (2018) Felicia Gurău et al. AGEING RESEARCH REVIEWS
- Small extracellular vesicles and their miRNA cargo are anti-apoptotic members of the senescence-associated secretory phenotype
- (2018) Lucia Terlecki-Zaniewicz et al. Aging-US
- Aging impairs beige adipocyte differentiation of mesenchymal stem cells via the reduced expression of Sirtuin 1
- (2018) Vuong Cat Khanh et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Senescence-messaging secretome factors trigger premature senescence in human endometrium-derived stem cells
- (2018) Irina O. Vassilieva et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Elevated levels of the small GTPase Cdc42 induces senescence in male rat mesenchymal stem cells
- (2018) Bauyrzhan Umbayev et al. BIOGERONTOLOGY
- Hydrogen alleviates cellular senescence via regulation of ROS/p53/p21 pathway in bone marrow-derived mesenchymal stem cells in vivo
- (2018) Wenbo Zhang et al. BIOMEDICINE & PHARMACOTHERAPY
- Melatonin Rescues Mesenchymal Stem Cells from Senescence Induced by the Uremic Toxin p-Cresol via Inhibiting mTOR-Dependent Autophagy
- (2018) Seung Pil Yun et al. Biomolecules & Therapeutics
- Effect of nutritional supplement on bone marrow-derived mesenchymal stem cells from aplastic anaemia
- (2018) Shihua Luo et al. BRITISH JOURNAL OF NUTRITION
- Insulin-like growth factor binding protein 4 inhibits proliferation of bone marrow mesenchymal stem cells and enhances growth of neurospheres derived from the stem cells
- (2018) Huiwen Li et al. CELL BIOCHEMISTRY AND FUNCTION
- Current understanding and future perspectives of the roles of sirtuins in the reprogramming and differentiation of pluripotent stem cells
- (2018) Yi-Chao Hsu et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- The replicative senescent mesenchymal stem / stromal cells defect in DNA damage response and anti-oxidative capacity
- (2018) Jin Yu et al. International Journal of Medical Sciences
- Melatonin alleviates oxidative stress-inhibited osteogenesis of human bone marrow-derived mesenchymal stem cells through AMPK activation
- (2018) Sooho Lee et al. International Journal of Medical Sciences
- The Dietary Antioxidant Piceatannol Inhibits Adipogenesis of Human Adipose Mesenchymal Stem Cells and Limits Glucose Transport and Lipogenic Activities in Adipocytes
- (2018) Christian Carpéné et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Blocking Nox2 improves mesenchymal stem cells therapy in myocardial infarction via antagonizing oxidant and promoting survival
- (2018) Dan Feng et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Fucoidan Rescues p-Cresol-Induced Cellular Senescence in Mesenchymal Stem Cells via FAK-Akt-TWIST Axis
- (2018) Jun Lee et al. Marine Drugs
- Overexpression of Sirt1 in Mesenchymal Stem Cells Protects against Bone Loss in Mice by FOXO3a Deacetylation and Oxidative Stress Inhibition
- (2018) Wen Sun et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Investigation of quercetin and hyperoside as senolytics in adult human endothelial cells
- (2018) HyunTae V. Hwang et al. PLoS One
- The variable role of SIRT1 in the maintenance and differentiation of mesenchymal stem cells
- (2018) Kayvan Zainabadi Regenerative Medicine
- Dysfunction of Mesenchymal Stem Cells Isolated from Metabolic Syndrome and Type 2 Diabetic Patients as Result of Oxidative Stress and Autophagy may Limit Their Potential Therapeutic Use
- (2018) Katarzyna Kornicka et al. Stem Cell Reviews and Reports
- Notch Signaling Enhances Stemness by Regulating Metabolic Pathways Through Modifying p53, NF-κB, and HIF-1α
- (2018) Hiroyuki Moriyama et al. STEM CELLS AND DEVELOPMENT
- Protein Synthesis Initiation in Eukaryotic Cells
- (2018) William C. Merrick et al. Cold Spring Harbor Perspectives in Biology
- Effects of senolytic drugs on human mesenchymal stromal cells
- (2018) Clara Grezella et al. Stem Cell Research & Therapy
- Inhibition of the RhoGTPase Cdc42 by ML141 enhances hepatocyte differentiation from human adipose-derived mesenchymal stem cells via the Wnt5a/PI3K/miR-122 pathway: impact of the age of the donor
- (2018) Diana Chaker et al. Stem Cell Research & Therapy
- Dysfunction of Mesenchymal Stem Cells Isolated from Metabolic Syndrome and Type 2 Diabetic Patients as Result of Oxidative Stress and Autophagy may Limit Their Potential Therapeutic Use
- (2018) Katarzyna Kornicka et al. Stem Cell Reviews and Reports
- Opposing Action of Hedgehog and Insulin Signaling Balances Proliferation and Autophagy to Determine Follicle Stem Cell Lifespan
- (2018) Tanu Singh et al. DEVELOPMENTAL CELL
- Emerging Roles of Sonic Hedgehog in Adult Neurological Diseases: Neurogenesis and Beyond
- (2018) Shang-Der Chen et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Regulation of the mitochondrial reactive oxygen species: Strategies to control mesenchymal stem cell fates ex vivo and in vivo
- (2018) Chenxia Hu et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
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- (2018) Hiroyuki Kawagishi et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
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- (2018) Yunlin Zeng et al. LIFE SCIENCES
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- (2018) Nayra Cárdenes et al. Stem Cell Research & Therapy
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- (2018) Jia Fang et al. Aging-US
- Evaluation of human mesenchymal stem cell senescence, differentiation and secretion behavior cultured on polycarbonate cell culture inserts
- (2018) Jie Zou et al. CLINICAL HEMORHEOLOGY AND MICROCIRCULATION
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- (2018) Lihua Chen et al. JOURNAL OF CHEMICAL PHYSICS
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- (2018) Jinjin Cui et al. LIFE SCIENCES
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- (2018) Lei Yang et al. MOLECULAR THERAPY
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- (2018) Jung Jang et al. MOLECULES
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- (2018) Umesh Goyal et al. STEM CELLS AND DEVELOPMENT
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- (2018) Ming Yang et al. Stem Cell Research & Therapy
- NADPH oxidase inhibitor apocynin decreases mitochondrial dysfunction and apoptosis in the ventral cochlear nucleus of D-galactose-induced aging model in rats
- (2018) Zheng-De Du et al. NEUROCHEMISTRY INTERNATIONAL
- Proteasome activation enhances stemness and lifespan of human mesenchymal stem cells
- (2017) Marianna Kapetanou et al. FREE RADICAL BIOLOGY AND MEDICINE
- The Hayflick Limit and Age-Related Adaptive Immune Deficiency
- (2017) Zoe Gill et al. GERONTOLOGY
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- (2017) Nicole M. Templeman et al. JOURNAL OF CELL BIOLOGY
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- (2017) Courtney L. Klaips et al. JOURNAL OF CELL BIOLOGY
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- (2017) Soon Yong Park et al. JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY
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- (2017) Katarzyna A. Cieslik et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
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- (2017) Fan Yang et al. JOURNAL OF PINEAL RESEARCH
- Spirulina platensis Improves Mitochondrial Function Impaired by Elevated Oxidative Stress in Adipose-Derived Mesenchymal Stromal Cells (ASCs) and Intestinal Epithelial Cells (IECs), and Enhances Insulin Sensitivity in Equine Metabolic Syndrome (EMS) Horses
- (2017) Daria Nawrocka et al. Marine Drugs
- High glucose induces the aging of mesenchymal stem cells via Akt/mTOR signaling
- (2017) Dayong Zhang et al. Molecular Medicine Reports
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- (2017) Ryan A. Denu Oxidative Medicine and Cellular Longevity
- Alpha-Ketoglutarate Curbs Differentiation and Induces Cell Death in Mesenchymal Stromal Precursors with Mitochondrial Dysfunction
- (2017) Karmveer Singh et al. STEM CELLS
- Knockdown of IL-8 Provoked Premature Senescence of Placenta-Derived Mesenchymal Stem Cells
- (2017) Juan-Juan Li et al. STEM CELLS AND DEVELOPMENT
- P53 Mutation and Epigenetic Imprinted IGF2/H19 Gene Analysis in Mesenchymal Stem Cells Derived from Amniotic Fluid, Amnion, Endometrium, and Wharton's Jelly
- (2017) Tatsanee Phermthai et al. STEM CELLS AND DEVELOPMENT
- In vitro expansion impaired the stemness of early passage mesenchymal stem cells for treatment of cartilage defects
- (2017) Tongmeng Jiang et al. Cell Death & Disease
- Physical activity and telomere length: Impact of aging and potential mechanisms of action
- (2017) Nicole C. Arsenis et al. Oncotarget
- Inhibition of iron overload-induced apoptosis and necrosis of bone marrow mesenchymal stem cells by melatonin
- (2017) Fan Yang et al. Oncotarget
- Material-induced Senescence (MIS): Fluidity Induces Senescent Type Cell Death of Lung Cancer Cells via Insulin-Like Growth Factor Binding Protein 5
- (2017) Sharmy Saimon Mano et al. Theranostics
- Oxidative Stress in Mesenchymal Stem Cell Senescence: Regulation by Coding and Noncoding RNAs
- (2017) Rosa Vono et al. ANTIOXIDANTS & REDOX SIGNALING
- Nampt Expression Decreases Age-Related Senescence in Rat Bone Marrow Mesenchymal Stem Cells by Targeting Sirt1
- (2017) Cao Ma et al. PLoS One
- 5-methoxytryptophan protects MSCs from stress induced premature senescence by upregulating FoxO3a and mTOR
- (2017) Tzu-Ching Chang et al. Scientific Reports
- Senescence-associated DNA methylation is stochastically acquired in subpopulations of mesenchymal stem cells
- (2016) Julia Franzen et al. AGING CELL
- Identification of a novel senolytic agent, navitoclax, targeting the Bcl-2 family of anti-apoptotic factors
- (2016) Yi Zhu et al. AGING CELL
- Growth differentiation factor 6 derived from mesenchymal stem/stromal cells reduces age-related functional deterioration in multiple tissues
- (2016) Daisuke Hisamatsu et al. Aging-US
- Accumulation of spontaneous γH2AX foci in long-term cultured mesenchymal stromal cells
- (2016) Margarita Pustovalova et al. Aging-US
- Discovery of piperlongumine as a potential novel lead for the development of senolytic agents
- (2016) Yingying Wang et al. Aging-US
- Unbiased analysis of senescence associated secretory phenotype (SASP) to identify common components following different genotoxic stresses
- (2016) Servet Özcan et al. Aging-US
- Senescence-Associated MCP-1 Secretion Is Dependent on a Decline in BMI1 in Human Mesenchymal Stromal Cells
- (2016) Hye Jin Jin et al. ANTIOXIDANTS & REDOX SIGNALING
- Epigenetic Mechanisms of Longevity and Aging
- (2016) Payel Sen et al. CELL
- Leptin Receptor Promotes Adipogenesis and Reduces Osteogenesis by Regulating Mesenchymal Stromal Cells in Adult Bone Marrow
- (2016) Rui Yue et al. Cell Stem Cell
- Pleiotropic Effects of Tocotrienols and Quercetin on Cellular Senescence: Introducing the Perspective of Senolytic Effects of Phytochemicals
- (2016) Marco Malavolta et al. CURRENT DRUG TARGETS
- Keeping the senescence secretome under control: Molecular reins on the senescence-associated secretory phenotype
- (2016) Nicolas Malaquin et al. EXPERIMENTAL GERONTOLOGY
- The effects of the DNA methyltranfserases inhibitor 5-Azacitidine on ageing, oxidative stress and DNA methylation of adipose derived stem cells
- (2016) Katarzyna Kornicka et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Mesenchymal stem cell-derived inflammatory fibroblasts mediate interstitial fibrosis in the aging heart
- (2016) JoAnn Trial et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Decreased osteogenesis in mesenchymal stem cells derived from the aged mouse is associated with enhanced NF-κB activity
- (2016) Tzu-hua Lin et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Infrapatellar fat pad-derived mesenchymal stromal cells from osteoarthritis patients: In vitro genetic stability and replicative senescence
- (2016) Simona Neri et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Age-associated hydroxymethylation in human bone-marrow mesenchymal stem cells
- (2016) Estela G. Toraño et al. Journal of Translational Medicine
- Effects of Oxidative Stress on Mesenchymal Stem Cell Biology
- (2016) Ryan A. Denu et al. Oxidative Medicine and Cellular Longevity
- ROS, Cell Senescence, and Novel Molecular Mechanisms in Aging and Age-Related Diseases
- (2016) Pierpaola Davalli et al. Oxidative Medicine and Cellular Longevity
- MiR-211/STAT5A Signaling Modulates Migration of Mesenchymal Stem Cells to Improve its Therapeutic Efficacy
- (2016) Xinyang Hu et al. STEM CELLS
- Aging Reduces an ERRalpha-Directed Mitochondrial Glutaminase Expression Suppressing Glutamine Anaplerosis and Osteogenic Differentiation of Mesenchymal Stem Cells
- (2016) Tongling Huang et al. STEM CELLS
- Enhancer of Zeste Homolog 2 and Histone Deacetylase 9c Regulate Age-Dependent Mesenchymal Stem Cell Differentiation into Osteoblasts and Adipocytes
- (2016) Ya-Huey Chen et al. STEM CELLS
- Identity, proliferation capacity, genomic stability and novel senescence markers of mesenchymal stem cells isolated from low volume of human bone marrow
- (2016) Gabrielis Kundrotas et al. Oncotarget
- Vitamin C alleviates aging defects in a stem cell model for Werner syndrome
- (2016) Ying Li et al. Protein & Cell
- Platelet-Derived Growth Factor-BB Protects Mesenchymal Stem Cells (MSCs) Derived From Immune Thrombocytopenia Patients Against Apoptosis and Senescence and Maintains MSC-Mediated Immunosuppression
- (2016) Jia-min Zhang et al. Stem Cells Translational Medicine
- Senescence-Associated Molecular and Epigenetic Alterations in Mesenchymal Stem Cell Cultures from Amniotic Fluid of Normal and Fetus-Affected Pregnancy
- (2016) Jūratė Savickienė et al. Stem Cells International
- Characterization and Expression of Senescence Marker in Prolonged Passages of Rat Bone Marrow-Derived Mesenchymal Stem Cells
- (2016) Noridzzaida Ridzuan et al. Stem Cells International
- Detection of mesenchymal stem cells senescence by prelamin A accumulation at the nuclear level
- (2016) Chiara Bellotti et al. SpringerPlus
- The HIV proteins Tat and Nef promote human bone marrow mesenchymal stem cell senescence and alter osteoblastic differentiation
- (2015) Carine Beaupere et al. AGING CELL
- The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs
- (2015) Yi Zhu et al. AGING CELL
- Telomerase activity promotes osteoblast differentiation by modulating IGF-signaling pathway
- (2015) Hamid Saeed et al. BIOGERONTOLOGY
- Mitochondrial metabolic failure in telomere attrition-provoked aging of bone marrow mesenchymal stem cells
- (2015) Bingdong Sui et al. BIOGERONTOLOGY
- Pretreatment with Lycopene Attenuates Oxidative Stress-Induced Apoptosis in Human Mesenchymal Stem Cells
- (2015) Ji Yong Kim et al. Biomolecules & Therapeutics
- Targeting colorectal cancer stem cells using curcumin and curcumin analogues: insights into the mechanism of the therapeutic efficacy
- (2015) Thamil Selvee Ramasamy et al. Cancer Cell International
- Expression of human telomerase reverse transcriptase mediates the senescence of mesenchymal stem cells through the PI3K/AKT signaling pathway
- (2015) QIANG ZHAO et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- MicroRNA-188 regulates age-related switch between osteoblast and adipocyte differentiation
- (2015) Chang-Jun Li et al. JOURNAL OF CLINICAL INVESTIGATION
- Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice
- (2015) Jianhui Chang et al. NATURE MEDICINE
- Longevity and aging. Mechanisms and perspectives
- (2015) J. Labat-Robert et al. PATHOLOGIE BIOLOGIE
- Genetic and epigenetic alterations of bone marrow stromal cells in myelodysplastic syndrome and acute myeloid leukemia patients
- (2015) Yonggoo Kim et al. Stem Cell Research
- Zoledronate Attenuates Accumulation of DNA Damage in Mesenchymal Stem Cells and Protects Their Function
- (2015) Juhi Misra et al. STEM CELLS
- Umbilical Cord Mesenchymal Stromal Cells Affected by Gestational Diabetes Mellitus Display Premature Aging and Mitochondrial Dysfunction
- (2015) Jooyeon Kim et al. STEM CELLS AND DEVELOPMENT
- c-Maf regulates pluripotency genes, proliferation/self-renewal, and lineage commitment in ROS-mediated senescence of human mesenchymal stem cells
- (2015) Pei-Min Chen et al. Oncotarget
- Macrophage migration inhibitory factor confers resistance to senescence through CD74-dependent AMPK-FOXO3a signaling in mesenchymal stem cells
- (2015) Wenzheng Xia et al. Stem Cell Research & Therapy
- Sonic the Hedgehog: A game about aging? Emerging evidence for anti-geriatric effects of Hedgehog signaling (retrospective on DOI 10.1002/bies.201200049)
- (2014) Matthias Lauth BIOESSAYS
- Mesenchymal Derivatives of Genetically Unstable Human Embryonic Stem Cells Are Maintained Unstable but Undergo Senescence in Culture As Do Bone Marrow–Derived Mesenchymal Stem Cells
- (2014) Angeliki Karagiannidou et al. Cellular Reprogramming
- Placental mesenchymal stem cells of fetal origin deposit epigenetic alterations during long-term culture under serum-free condition
- (2014) Yongzhao Zhu et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Caloric restriction and the aging process: a critique
- (2014) Rajindar S. Sohal et al. FREE RADICAL BIOLOGY AND MEDICINE
- Epigenetics of Aging and Aging-related Disease
- (2014) A. Brunet et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Metabolism of stromal and immune cells in health and disease
- (2014) Bart Ghesquière et al. NATURE
- Dauer-independent insulin/IGF-1-signalling implicates collagen remodelling in longevity
- (2014) Collin Y. Ewald et al. NATURE
- Telomerase Protects Werner Syndrome Lineage-Specific Stem Cells from Premature Aging
- (2014) Hoi-Hung Cheung et al. Stem Cell Reports
- Role of SIRT1 and AMPK in mesenchymal stem cells differentiation
- (2013) Huiqiang Chen et al. AGEING RESEARCH REVIEWS
- Genome Instability and Aging
- (2013) Jan Vijg et al. Annual Review of Physiology
- Robustness and aging—A systems-level perspective
- (2013) Andres Kriete BIOSYSTEMS
- The Hallmarks of Aging
- (2013) Carlos López-Otín et al. CELL
- Culture expansion induces non-tumorigenic aneuploidy in adipose tissue-derived mesenchymal stromal cells
- (2013) Marieke Roemeling-van Rhijn et al. CYTOTHERAPY
- Inhibition of non-muscle myosin II leads to G0/G1 arrest of Wharton's jelly-derived mesenchymal stromal cells
- (2013) Tulika Sharma et al. CYTOTHERAPY
- mTOR is a key modulator of ageing and age-related disease
- (2013) Simon C. Johnson et al. NATURE
- Senescence and aging: the critical roles of p53
- (2013) A Rufini et al. ONCOGENE
- Human Umbilical Cord Matrix Stem Cells Maintain Multilineage Differentiation Abilities and Do Not Transform during Long-Term Culture
- (2013) Isabelle Scheers et al. PLoS One
- Human mesenchymal stem cell-replicative senescence and oxidative stress are closely linked to aneuploidy
- (2013) J C Estrada et al. Cell Death & Disease
- Insulin-like growth factor binding proteins 4 and 7 released by senescent cells promote premature senescence in mesenchymal stem cells
- (2013) V Severino et al. Cell Death & Disease
- Aging, Rejuvenation, and Epigenetic Reprogramming: Resetting the Aging Clock
- (2012) Thomas A. Rando et al. CELL
- HSF-1 Regulators DDL-1/2 Link Insulin-like Signaling to Heat-Shock Responses and Modulation of Longevity
- (2012) Wei-Chung Chiang et al. CELL
- mTOR Signaling in Growth Control and Disease
- (2012) Mathieu Laplante et al. CELL
- The Critical Role of Metabolic Pathways in Aging
- (2012) N. Barzilai et al. DIABETES
- Hsp72 preserves muscle function and slows progression of severe muscular dystrophy
- (2012) Stefan M. Gehrig et al. NATURE
- Nutraceutical Interventions for Promoting Healthy Aging in Invertebrate Models
- (2012) Yuqing Dong et al. Oxidative Medicine and Cellular Longevity
- Implications of long-term culture for mesenchymal stem cells: genetic defects or epigenetic regulation?
- (2012) Wolfgang Wagner Stem Cell Research & Therapy
- Oxidative stress induces senescence in human mesenchymal stem cells
- (2011) Anita Brandl et al. EXPERIMENTAL CELL RESEARCH
- Estrogen reduces cellular aging in human mesenchymal stem cells and chondrocytes
- (2011) Anita Breu et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Role of AMPK-mTOR-Ulk1/2 in the Regulation of Autophagy: Cross Talk, Shortcuts, and Feedbacks
- (2011) S. Alers et al. MOLECULAR AND CELLULAR BIOLOGY
- Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
- (2011) Darren J. Baker et al. NATURE
- Metabolic Networks of Longevity
- (2010) Riekelt H. Houtkooper et al. CELL
- FOXO/4E-BP Signaling in Drosophila Muscles Regulates Organism-wide Proteostasis during Aging
- (2010) Fabio Demontis et al. CELL
- The metabolism of human mesenchymal stem cells during proliferation and differentiation
- (2010) Girish Pattappa et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice
- (2010) Mariela Jaskelioff et al. NATURE
- Progeria syndromes and ageing: what is the connection?
- (2010) Christopher R. Burtner et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Caloric restriction: From soup to nuts
- (2009) Stephen R. Spindler AGEING RESEARCH REVIEWS
- Biological and Chemical Approaches to Diseases of Proteostasis Deficiency
- (2009) Evan T. Powers et al. Annual Review of Biochemistry
- Aging is not senescence: a short computer demonstration and implications for medical practice
- (2009) Thiago Oliveira Monaco et al. Clinics
- Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
- (2009) David E. Harrison et al. NATURE
- AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
- (2009) Carles Cantó et al. NATURE
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