Implications of long-term culture for mesenchymal stem cells: genetic defects or epigenetic regulation?

From cytogenomic to epigenomic profiles: monitoring the biological behavior of in vitro cultured human bone marrow mesenchymal stem cells

(2012) Serena Redaelli et al.   Stem Cell Research & Therapy

Monitoring of cellular senescence by DNA-methylation at specific CpG sites

(2011) Carmen M. Koch et al.   AGING CELL

Rejuvenating senescent and centenarian human cells by reprogramming through the pluripotent state

(2011) L. Lapasset et al.   GENES & DEVELOPMENT

Spontaneous Malignant Transformation of Human Mesenchymal Stem Cells Reflects Cross-Contamination: Putting the Research Field on Track - Letter

(2010) A. Torsvik et al.   CANCER RESEARCH

Pitfalls in spontaneous in vitro transformation of human mesenchymal stem cells

(2010) S. Garcia et al.   EXPERIMENTAL CELL RESEARCH

DNA methylation pattern changes upon long-term culture and aging of human mesenchymal stromal cells

(2009) Simone Bork et al.   AGING CELL

Clinical-grade production of human mesenchymal stromal cells: occurrence of aneuploidy without transformation

(2009) K. Tarte et al.   BLOOD