Proteomic and Biological Analysis of the Effects of Metformin Senomorphics on the Mesenchymal Stromal Cells

Metformin inhibits chronic kidney disease‐induced DNA damage and senescence of mesenchymal stem cells

(2021) Hyoungnae Kim et al.   AGING CELL

Cysteine Depletion, a Key Action to Challenge Cancer Cells to Ferroptotic Cell Death

(2020) Boutaina Daher et al.   Frontiers in Oncology

A comparative study on normal and obese mice indicates that the secretome of mesenchymal stromal cells is influenced by tissue environment and physiopathological conditions

(2020) Serife Ayaz-Guner et al.   Cell Communication and Signaling

Cellular and Molecular Mechanisms of Metformin Action

(2020) Traci E LaMoia et al.   ENDOCRINE REVIEWS

Metformin Augments Anti-Inflammatory and Chondroprotective Properties of Mesenchymal Stem Cells in Experimental Osteoarthritis

(2019) Min-Jung Park et al.   JOURNAL OF IMMUNOLOGY

Progression of the role of CRYAB in signaling pathways and cancers

(2019) Junfei Zhang et al.   OncoTargets and Therapy

Iron homeostasis and iron-regulated ROS in cell death, senescence and human diseases

(2019) Toshitaka Nakamura et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Metformin prevents against oxidative stress-induced senescence in human periodontal ligament cells

(2019) Yunchun Kuang et al.   BIOGERONTOLOGY

HSP90 inhibitors stimulate DNAJB4 protein expression through a mechanism involving N6-methyladenosine

(2019) Weili Miao et al.   Nature Communications

Full title: High glucose protects mesenchymal stem cells from metformin-induced apoptosis through the AMPK-mediated mTOR pathway

(2019) Xiao He et al.   Scientific Reports

Range of therapeutic metformin concentrations in clinical blood samples and comparison to a forensic case with death due to lactic acidosis

(2018) C. Hess et al.   FORENSIC SCIENCE INTERNATIONAL

Senotherapeutics for healthy ageing

(2018) Laura J. Niedernhofer et al.   NATURE REVIEWS DRUG DISCOVERY

Senescence and senotherapeutics: a new field in cancer therapy

(2018) Vassilios Myrianthopoulos et al.   PHARMACOLOGY & THERAPEUTICS

Prolonged incubation with Metformin decreased angiogenic potential in human bone marrow mesenchymal stem cells

(2018) Soheila Montazersaheb et al.   BIOMEDICINE & PHARMACOTHERAPY

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

PXR: More Than Just a Master Xenobiotic Receptor

(2017) Peter O. Oladimeji et al.   MOLECULAR PHARMACOLOGY

Metformin Enhances Osteogenesis and Suppresses Adipogenesis of Human Chorionic Villous Mesenchymal Stem Cells

(2017) Qiaoli Gu et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

Telomeres and Cell Senescence - Size Matters Not

(2017) Stella Victorelli et al.   EBioMedicine

Unbiased analysis of senescence associated secretory phenotype (SASP) to identify common components following different genotoxic stresses

(2016) Servet Özcan et al.   Aging-US

Clinical Trials with Mesenchymal Stem Cells: An Update

(2016) Tiziana Squillaro et al.   CELL TRANSPLANTATION

Metformin Decreases Reactive Oxygen Species, Enhances Osteogenic Properties of Adipose-Derived Multipotent Mesenchymal Stem Cells In Vitro, and Increases Bone Density In Vivo

(2016) Krzysztof Marycz et al.   Oxidative Medicine and Cellular Longevity

ROS, Cell Senescence, and Novel Molecular Mechanisms in Aging and Age-Related Diseases

(2016) Pierpaola Davalli et al.   Oxidative Medicine and Cellular Longevity

Activation of β-adrenergic receptors is required for elevated α1A-adrenoreceptors expression and signaling in mesenchymal stromal cells

(2016) Pyotr A. Tyurin-Kuzmin et al.   Scientific Reports

The role of senescent cells in ageing

(2014) Jan M. van Deursen   NATURE

Minimal, encapsulated proteomic-sample processing applied to copy-number estimation in eukaryotic cells

(2014) Nils A Kulak et al.   NATURE METHODS

Cisplatin-induced senescence in ovarian cancer cells is mediated by GRP78

(2014) WEI LI et al.   ONCOLOGY REPORTS

Gas chromatography–mass spectrometry analysis of human mesenchymal stem cell metabolism during proliferation and osteogenic differentiation under different oxygen tensions

(2013) Nathalie Muñoz et al.   JOURNAL OF BIOTECHNOLOGY

NF-κB Accumulation Associated with COL1A1 Trans activators Defects during Chronological Aging Represses Type I Collagen Expression through a –112/–61-bp Region of the COL1A1 Promoter in Human Skin Fibroblasts

(2012) Nicolas Bigot et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Dopamine Regulates Mobilization of Mesenchymal Stem Cells during Wound Angiogenesis

(2012) Saurav Shome et al.   PLoS One

Protocols to detect senescence-associated beta-galactosidase (SA-βgal) activity, a biomarker of senescent cells in culture and in vivo

(2009) Florence Debacq-Chainiaux et al.   Nature Protocols

Toll-Like Receptor Engagement Enhances the Immunosuppressive Properties of Human Bone Marrow-Derived Mesenchymal Stem Cells by Inducing Indoleamine-2,3-dioxygenase-1 via Interferon-β and Protein Kinase R

(2009) Christiane A. Opitz et al.   STEM CELLS

Metformin regulates osteoblast and adipocyte differentiation of rat mesenchymal stem cells

(2008) Ying Gao et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY