Long Non-Coding RNA KCNQ1OT1 Regulates Protein Kinase CK2 Via miR-760 in Senescence and Calorie Restriction

CK2 Down-Regulation Increases the Expression of Senescence-Associated Secretory Phenotype Factors through NF-κB Activation

(2021) Junbin Song et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Epigenetics, microRNA and Metabolic Syndrome: A Comprehensive Review

(2021) Farha Ramzan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

KCNQ1OT1: An Oncogenic Long Noncoding RNA

(2021) Patrice Cagle et al.   Biomolecules

LncRNA KCNQ1OT1 accelerates fracture healing via modulating miR‐701‐3p/FGFR3 axis

(2020) Lang Chen et al.   FASEB JOURNAL

Knockdown of KCNQ1OT1 attenuates cardiac hypertrophy through modulation of the miR-2054/AKT3 axis

(2020) Yiwei Chen et al.   Journal of Thoracic Disease

LncRNA kcnq1ot1 promotes lipid accumulation and accelerates atherosclerosis via functioning as a ceRNA through the miR-452-3p/HDAC3/ABCA1 axis

(2020) Xiao-Hua Yu et al.   Cell Death & Disease

KCNQ1OT1 promotes autophagy by regulating miR‐200a/FOXO3/ATG7 pathway in cerebral ischemic stroke

(2019) Shijia Yu et al.   AGING CELL

Lnc RNA KCNQ 1 OT 1 enhanced the methotrexate resistance of colorectal cancer cells by regulating miR‐760/ PPP 1R1B via the cAMP signalling pathway

(2019) Di Xian et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

CK2 downregulation induces senescence-associated heterochromatic foci formation through activating SUV39h1 and inactivating G9a

(2018) Jeong-Woo Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Long noncoding RNA SNHG6 promotes the progression of colorectal cancer through sponging miR-760 and activation of FOXC1

(2018) Yuekun Zhu et al.   OncoTargets and Therapy

Silencing long non-coding RNA Kcnq1ot1 alleviates pyroptosis and fibrosis in diabetic cardiomyopathy

(2018) Fan Yang et al.   Cell Death & Disease

Senescence and aging: Causes, consequences, and therapeutic avenues

(2017) Domhnall McHugh et al.   JOURNAL OF CELL BIOLOGY

Unique features of long non-coding RNA biogenesis and function

(2016) Jeffrey J. Quinn et al.   NATURE REVIEWS GENETICS

Regulation of functional KCNQ1OT1 lncRNA by β-catenin

(2016) Naohiro Sunamura et al.   Scientific Reports

Cellular senescence in aging and age-related disease: from mechanisms to therapy

(2015) Bennett G Childs et al.   NATURE MEDICINE

Upregulation of miR-760 and miR-186 Is Associated with Replicative Senescence in Human Lung Fibroblast Cells

(2014) Young-Hoon Lee et al.   MOLECULES AND CELLS

lincRNAs: Genomics, Evolution, and Mechanisms

(2013) Igor Ulitsky et al.   CELL

miR-186, miR-216b, miR-337-3p, and miR-760 cooperatively induce cellular senescence by targeting α subunit of protein kinase CKII in human colorectal cancer cells

(2012) Soo Young Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Non-coding RNAs in human disease

(2011) Manel Esteller   NATURE REVIEWS GENETICS

Kcnq1ot1: A chromatin regulatory RNA

(2011) Chandrasekhar Kanduri   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

NADPH oxidase is involved in protein kinase CKII down-regulation-mediated senescence through elevation of the level of reactive oxygen species in human colon cancer cells

(2010) Seon Min Jeon et al.   FEBS LETTERS

The p53-p21Cip1/WAF1 pathway is necessary for cellular senescence induced by the inhibition of protein kinase CKII in human colon cancer cells

(2009) Ji-Young Kang et al.   MOLECULES AND CELLS

Kcnq1ot1 Antisense Noncoding RNA Mediates Lineage-Specific Transcriptional Silencing through Chromatin-Level Regulation

(2008) Radha Raman Pandey et al.   MOLECULAR CELL