Regulation and signaling pathways in cancer stem cells: implications for targeted therapy for cancer
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Regulation and signaling pathways in cancer stem cells: implications for targeted therapy for cancer
Authors
Keywords
-
Journal
Molecular Cancer
Volume 22, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2023-10-18
DOI
10.1186/s12943-023-01877-w
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Glutamine Metabolism in Cancer Stem Cells: A Complex Liaison in the Tumor Microenvironment
- (2023) Francesco Pacifico et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Prognostic factors of childhood acute lymphoblastic leukemia with TCF3::PBX1 in CCCG‐ALL‐2015: A multicenter study
- (2023) Honghong Zhang et al. CANCER
- RNA-binding protein complex LIN28/MSI2 enhances cancer stem cell-like properties by modulating Hippo-YAP1 signaling and independently of Let-7
- (2022) Hailin Zou et al. ONCOGENE
- Cancer stem cells: The adventurous journey from hematopoietic to leukemic stem cells
- (2022) Andreas Trumpp et al. CELL
- Novel dual-targeting c-Myc inhibitor D347-2761 represses myeloma growth via blocking c-Myc/Max heterodimerization and disturbing its stability
- (2022) Ruosi Yao et al. Cell Communication and Signaling
- Glutaminase inhibition impairs CD8 T cell activation in STK11-/Lkb1-deficient lung cancer
- (2022) Sarah A. Best et al. Cell Metabolism
- A Functional Screening Identifies a New Organic Selenium Compound Targeting Cancer Stem Cells: Role of c‐Myc Transcription Activity Inhibition in Liver Cancer
- (2022) Jun‐Nian Zhou et al. Advanced Science
- Correction: SIK2 maintains breast cancer stemness by phosphorylating LRP6 and activating Wnt/β-catenin signaling
- (2022) Zhuoxian Rong et al. ONCOGENE
- A novel hypoxic long noncoding RNA KB-1980E6.3 maintains breast cancer stem cell stemness via interacting with IGF2BP1 to facilitate c-Myc mRNA stability
- (2021) Pengpeng Zhu et al. ONCOGENE
- Targeting the Sonic Hedgehog Pathway to Suppress the Expression of the Cancer Stem Cell (CSC)—Related Transcription Factors and CSC-Driven Thyroid Tumor Growth
- (2021) Yurong Lu et al. Cancers
- Glasdegib in newly diagnosed acute myeloid leukemia
- (2021) Shawn M Sarkaria et al. Expert Review of Anticancer Therapy
- RALYL increases hepatocellular carcinoma stemness by sustaining the mRNA stability of TGF-β2
- (2021) Xia Wang et al. Nature Communications
- The Role of Autophagy and lncRNAs in the Maintenance of Cancer Stem Cells
- (2021) Leila Jahangiri et al. Cancers
- Deciphering the Role of Intestinal Crypt Cell Populations in Resistance to Chemotherapy
- (2021) Carla Frau et al. CANCER RESEARCH
- Mitochondrial Fuel Dependence on Glutamine Drives Chemo-Resistance in the Cancer Stem Cells of Hepatocellular Carcinoma
- (2021) Alan Chun Kit Lee et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Novel therapies emerging in oncology to target the TGF-β pathway
- (2021) Byung-Gyu Kim et al. Journal of Hematology & Oncology
- Sequence determinants, function, and evolution of CpG islands
- (2021) Allegra Angeloni et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- BAG3 epigenetically regulates GALNT10 expression via WDR5 and facilitates the stem cell-like properties of platin-resistant ovarian cancer cells
- (2021) Fu-Ying Zhao et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Pancreatic Tumor Microenvironment Factor Promotes Cancer Stemness via SPP1-CD44 Axis
- (2021) Palanisamy Nallasamy et al. GASTROENTEROLOGY
- YTHDF2 facilitates UBXN1 mRNA decay by recognizing METTL3-mediated m6A modification to activate NF-κB and promote the malignant progression of glioma
- (2021) Rui-Chao Chai et al. Journal of Hematology & Oncology
- DNMT1-mediated methylation of BEX1 regulates stemness and tumorigenicity in liver cancer
- (2021) Qian Wang et al. JOURNAL OF HEPATOLOGY
- An ADAR1-dependent RNA editing event in the cyclin-dependent kinase CDK13 promotes thyroid cancer hallmarks
- (2021) Julia Ramírez-Moya et al. Molecular Cancer
- Givinostat as metabolic enhancer reverting mitochondrial biogenesis deficit in Duchenne Muscular Dystrophy
- (2021) Matteo Giovarelli et al. PHARMACOLOGICAL RESEARCH
- PCGF1 promotes epigenetic activation of stemness markers and colorectal cancer stem cell enrichment
- (2021) Guangyu Ji et al. Cell Death & Disease
- HIST2H2BF Potentiates the Propagation of Cancer Stem Cells via Notch Signaling to Promote Malignancy and Liver Metastasis in Colorectal Carcinoma
- (2021) Lei Qiu et al. Frontiers in Oncology
- Venetoclax and azacitidine followed by allogeneic transplant results in excellent outcomes and may improve outcomes versus maintenance therapy among newly diagnosed AML patients older than 60
- (2021) Daniel A. Pollyea et al. BONE MARROW TRANSPLANTATION
- Dual Knockdown of Musashi RNA-Binding Proteins MSI-1 and MSI-2 Attenuates Putative Cancer Stem Cell Characteristics and Therapy Resistance in Ovarian Cancer Cells
- (2021) Maria T. Löblein et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- A novel lncRNA ROPM-mediated lipid metabolism governs breast cancer stem cell properties
- (2021) Shuiqing Liu et al. Journal of Hematology & Oncology
- Targeting CD123 in BPDCN: an emerging field
- (2021) Adam J DiPippo et al. Expert Review of Hematology
- Development of small molecule inhibitors targeting PBX1 transcription signaling as a novel cancer therapeutic strategy
- (2021) Yao-An Shen et al. iScience
- Sonic Hedgehog Signaling in Organogenesis, Tumors, and Tumor Microenvironments
- (2020) Kuo-Shyang Jeng et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Targeting SOX2 Protein with Peptide Aptamers for Therapeutic Gains against Esophageal Squamous Cell Carcinoma
- (2020) Kuancan Liu et al. MOLECULAR THERAPY
- RNA modifications and cancer
- (2020) Phensinee Haruehanroengra et al. RNA Biology
- Inhibiting WNT and NOTCH in renal cancer stem cells and the implications for human patients
- (2020) Annika Fendler et al. Nature Communications
- ZHX2 restricts hepatocellular carcinoma by suppressing stem cell-like traits through KDM2A-mediated H3K36 demethylation
- (2020) Qinghai Lin et al. EBioMedicine
- Role of JAK/STAT3 Signaling in the Regulation of Metastasis, the Transition of Cancer Stem Cells, and Chemoresistance of Cancer by Epithelial–Mesenchymal Transition
- (2020) Wook Jin Cells
- Identification of Cancer Stem Cell Subpopulations in Head and Neck Metastatic Malignant Melanoma
- (2020) Vithushiya Yoganandarajah et al. Cells
- RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia
- (2020) Chao Shen et al. Cell Stem Cell
- Discovery of (2R)-N-[3-[2-[(3-Methoxy-1-methyl-pyrazol-4-yl)amino]pyrimidin-4-yl]-1H-indol-7-yl]-2-(4-methylpiperazin-1-yl)propenamide (AZD4205) as a Potent and Selective Janus Kinase 1 Inhibitor
- (2020) Qibin Su et al. JOURNAL OF MEDICINAL CHEMISTRY
- Safety and efficacy of talacotuzumab plus decitabine or decitabine alone in patients with acute myeloid leukemia not eligible for chemotherapy: results from a multicenter, randomized, phase 2/3 study
- (2020) Pau Montesinos et al. LEUKEMIA
- A Highly Potent TACC3 Inhibitor as a Novel Anticancer Drug Candidate
- (2020) Ozge Akbulut et al. MOLECULAR CANCER THERAPEUTICS
- lncRNA MALAT1 modulates cancer stem cell properties of liver cancer cells by regulating YAP1 expression via miR‑375 sponging
- (2020) Liying Zhao et al. Molecular Medicine Reports
- YTHDF2 promotes the liver cancer stem cell phenotype and cancer metastasis by regulating OCT4 expression via m6A RNA methylation
- (2020) Chuanzhao Zhang et al. ONCOGENE
- Heterogeneity in mRNA Translation
- (2020) Stijn Sonneveld et al. TRENDS IN CELL BIOLOGY
- HyperTRIBE uncovers increased MUSASHI-2 RNA binding activity and differential regulation in leukemic stem cells
- (2020) Diu T. T. Nguyen et al. Nature Communications
- Targeting Aldehyde Dehydrogenases to Eliminate Cancer Stem Cells in Gynecologic Malignancies
- (2020) Vaishnavi Muralikrishnan et al. Cancers
- Inhibition of Wnt/β-catenin pathway reverses multi-drug resistance and EMT in Oct4+/Nanog+ NSCLC cells
- (2020) Liyun Liu et al. BIOMEDICINE & PHARMACOTHERAPY
- Nanog mediates tobacco smoke‐induced enhancement of renal cancer stem cell properties
- (2020) Taotao Zhang et al. ENVIRONMENTAL TOXICOLOGY
- A novel miR-200c/c-myc negative regulatory feedback loop is essential to the EMT process, CSC biology and drug sensitivity in nasopharyngeal cancer
- (2020) Jing Yang et al. EXPERIMENTAL CELL RESEARCH
- Oct4 promotes M2 macrophage polarization through upregulation of macrophage colony-stimulating factor in lung cancer
- (2020) Chia-Sing Lu et al. Journal of Hematology & Oncology
- DOCK6 promotes chemo- and radioresistance of gastric cancer by modulating WNT/β-catenin signaling and cancer stem cell traits
- (2020) Hsiang-Cheng Chi et al. ONCOGENE
- TGF-β induced EMT and stemness characteristics are associated with epigenetic regulation in lung cancer
- (2020) Bit Na Kim et al. Scientific Reports
- RNA-Binding Protein Rbm24 as a Multifaceted Post-Transcriptional Regulator of Embryonic Lineage Differentiation and Cellular Homeostasis
- (2020) Raphaëlle Grifone et al. Cells
- Flotetuzumab as Salvage Immunotherapy for Refractory Acute Myeloid Leukemia
- (2020) Geoffrey L Uy et al. BLOOD
- Cancer Cell CD44 Mediates Macrophage/Monocyte-Driven Regulation of Head and Neck Cancer Stem Cells
- (2020) Karina E. Gomez et al. CANCER RESEARCH
- EZH2-Mediated Downregulation of the Tumor Suppressor DAB2IP Maintains Ovarian Cancer Stem Cells
- (2020) Xingyue Zong et al. CANCER RESEARCH
- In Colorectal Cancer Cells With Mutant KRAS, SLC25A22-Mediated Glutaminolysis Reduces DNA Demethylation to Increase WNT Signaling, Stemness, and Drug Resistance
- (2020) Chi Chun Wong et al. GASTROENTEROLOGY
- Sox2‐dependent maintenance of mouse oligodendroglioma involves the Sox2‐mediated downregulation of Cdkn2b, Ebf1, Zfp423, and Hey2
- (2020) Cristiana Barone et al. GLIA
- TGFβ-Directed Therapeutics: 2020
- (2020) Beverly A. Teicher PHARMACOLOGY & THERAPEUTICS
- 1,25-dihydroxyvitamin D3 signaling-induced decreases in IRX4 inhibits NANOG-mediated cancer stem-like properties and gefitinib resistance in NSCLC cells
- (2020) Zhirong Jia et al. Cell Death & Disease
- 5-FU promotes stemness of colorectal cancer via p53-mediated WNT/β-catenin pathway activation
- (2020) Yong-Hee Cho et al. Nature Communications
- A-to-I RNA editing as a tuner of noncoding RNAs in cancer
- (2020) Yuanfan Liao et al. CANCER LETTERS
- Oncostatin M: A mysterious cytokine in cancers
- (2020) Ali Masjedi et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- lncRNA involvement in cancer stem cell function and epithelial-mesenchymal transitions
- (2020) Evan M. McCabe et al. SEMINARS IN CANCER BIOLOGY
- A Novel Long Non‐Coding RNA lnc030 Maintains Breast Cancer Stem Cell Stemness by Stabilizing SQLE mRNA and Increasing Cholesterol Synthesis
- (2020) Yilu Qin et al. Advanced Science
- Metabolic Targeting of Cancer Stem Cells
- (2020) Anna Mukha et al. Frontiers in Oncology
- PRX2 Loss of Function Inhibits CSCs Propagation via ROS Imbalance in Hepatocellular Carcinoma Cells
- (2019) Yewon Son et al. FREE RADICAL BIOLOGY AND MEDICINE
- BCL-2 family isoforms in apoptosis and cancer
- (2019) Chloe F. A. Warren et al. Cell Death & Disease
- Downregulation of RNF128 activates Wnt/β-catenin signaling to induce cellular EMT and stemness via CD44 and CTTN ubiquitination in melanoma
- (2019) Chuan-Yuan Wei et al. Journal of Hematology & Oncology
- Biochemical mechanisms of vertebrate hedgehog signaling
- (2019) Jennifer H. Kong et al. DEVELOPMENT
- CXCL12/CXCR4 pathway orchestrates CSC-like properties by CAF recruited tumor associated macrophage in OSCC
- (2019) Xing Li et al. EXPERIMENTAL CELL RESEARCH
- Lnc RNA MALAT 1 increases the stemness of gastric cancer cells via enhancing SOX 2 mRNA stability
- (2019) Yiwen Xiao et al. FEBS Open Bio
- SET domain-containing protein 4 epigenetically controls breast cancer stem cell quiescence
- (2019) Sen Ye et al. CANCER RESEARCH
- RUNX3 suppresses metastasis and stemness by inhibiting Hedgehog signaling in colorectal cancer
- (2019) Bo Ram Kim et al. CELL DEATH AND DIFFERENTIATION
- New insight into NANOG: A novel therapeutic target for ovarian cancer (OC)
- (2019) Iyer Mahalaxmi et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Cancer stem cells: A review from origin to therapeutic implications
- (2019) Mohammad Reza Atashzar et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Tumor-associated macrophages in tumor metastasis: biological roles and clinical therapeutic applications
- (2019) Yuxin Lin et al. Journal of Hematology & Oncology
- METTL3 facilitates tumor progression via an m6A-IGF2BP2-dependent mechanism in colorectal carcinoma
- (2019) Ting Li et al. Molecular Cancer
- AMPA receptor GluA2 subunit defects are a cause of neurodevelopmental disorders
- (2019) Vincenzo Salpietro et al. Nature Communications
- Diversity, Mechanisms, and Significance of Macrophage Plasticity
- (2019) Massimo Locati et al. Annual Review of Pathology-Mechanisms of Disease
- miR-221 Targets QKI to Enhance the Tumorigenic Capacity of Human Colorectal Cancer Stem Cells
- (2019) Junko Mukohyama et al. CANCER RESEARCH
- N6-methyladenosine Modulates Nonsense-mediated mRNA Decay in Human Glioblastoma
- (2019) Fuxi Li et al. CANCER RESEARCH
- USP21 deubiquitinase promotes pancreas cancer cell stemness via Wnt pathway activation
- (2019) Pingping Hou et al. GENES & DEVELOPMENT
- The small molecule WNT/β-catenin inhibitor CWP232291 blocks the growth of castration-resistant prostate cancer by activating the endoplasmic reticulum stress pathway
- (2019) Sahyun Pak et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- The JAK2/STAT3/CCND2 Axis promotes colorectal Cancer stem cell persistence and radioresistance
- (2019) So-Yeon Park et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- SOX2 in development and cancer biology
- (2019) Daniel Novak et al. SEMINARS IN CANCER BIOLOGY
- Aldehyde Dehydrogenase Inhibitors for Cancer Therapeutics
- (2019) Saketh S. Dinavahi et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Epigenetic Regulation of Inflammatory Cytokine-Induced Epithelial-To-Mesenchymal Cell Transition and Cancer Stem Cell Generation
- (2019) Georgios S. Markopoulos et al. Cells
- Osteosarcoma‐initiating cells show high aerobic glycolysis and attenuation of oxidative phosphorylation mediated by LIN28B
- (2019) Emi Mizushima et al. CANCER SCIENCE
- The Effects of TGF-β Signaling on Cancer Cells and Cancer Stem Cells in the Bone Microenvironment
- (2019) Mitsuru Futakuchi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Long non-coding RNA GAS5 acts as proliferation “brakes” in CD133+ cells responsible for tumor recurrence
- (2019) Nikita S. Sharma et al. Oncogenesis
- Targeting Glycolysis with Epigallocatechin-3-Gallate Enhances the Efficacy of Chemotherapeutics in Pancreatic Cancer Cells and Xenografts
- (2019) Wei et al. Cancers
- Elevated GALNT10 expression identifies immunosuppressive microenvironment and dismal prognosis of patients with high grade serous ovarian cancer
- (2019) Guodong Zhang et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- ATXN3 promotes breast cancer metastasis by deubiquitinating KLF4
- (2019) Haojing Zou et al. CANCER LETTERS
- Efficacy of Ruxolitinib in Patients With Chronic Neutrophilic Leukemia and Atypical Chronic Myeloid Leukemia
- (2019) Kim-Hien T. Dao et al. JOURNAL OF CLINICAL ONCOLOGY
- Metformin attenuates hepatoma cell proliferation by decreasing glycolytic flux through the HIF-1α/PFKFB3/PFK1 pathway
- (2019) La Hu et al. LIFE SCIENCES
- Functions of N6-methyladenosine and its role in cancer
- (2019) Liuer He et al. Molecular Cancer
- Gigantol Targets Cancer Stem Cells and Destabilizes Tumors via the Suppression of the PI3K/AKT and JAK/STAT Pathways in Ectopic Lung Cancer Xenografts
- (2019) Nattanan Losuwannarak et al. Cancers
- KLF4 functions as an oncogene in promoting cancer stem cell-like characteristics in osteosarcoma cells
- (2018) Xiao-tian Qi et al. ACTA PHARMACOLOGICA SINICA
- A phase I dose-escalation and dose-expansion study of brontictuzumab in subjects with selected solid tumors
- (2018) R Ferrarotto et al. ANNALS OF ONCOLOGY
- Resveratrol suppresses migration, invasion and stemness of human breast cancer cells by interfering with tumor-stromal cross-talk
- (2018) Jinyoung Suh et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- TGF-β plays a vital role in triple-negative breast cancer (TNBC) drug-resistance through regulating stemness, EMT and apoptosis
- (2018) Xiaodan Xu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Cancer stem cells (CSCs): metabolic strategies for their identification and eradication
- (2018) Ernestina M. De Francesco et al. BIOCHEMICAL JOURNAL
- Single cell approaches identify the molecular network driving malignant hematopoietic stem cell self-renewal
- (2018) Mairi S. Shepherd et al. BLOOD
- Trends in the development of miRNA bioinformatics tools
- (2018) Liang Chen et al. BRIEFINGS IN BIOINFORMATICS
- Randomised phase II trial to investigate catumaxomab (anti-EpCAM × anti-CD3) for treatment of peritoneal carcinomatosis in patients with gastric cancer
- (2018) Maren Knödler et al. BRITISH JOURNAL OF CANCER
- CD10 + GPR77 + Cancer-Associated Fibroblasts Promote Cancer Formation and Chemoresistance by Sustaining Cancer Stemness
- (2018) Shicheng Su et al. CELL
- JAK/STAT3-Regulated Fatty Acid β-Oxidation Is Critical for Breast Cancer Stem Cell Self-Renewal and Chemoresistance
- (2018) Tianyi Wang et al. Cell Metabolism
- Evaluation of miRNA-21 and miRNA Let-7 as Prognostic Markers in Patients With Breast Cancer
- (2018) Eman A. Elghoroury et al. Clinical Breast Cancer
- RNA N6-methyladenosine methyltransferase-like 3 promotes liver cancer progression through YTHDF2-dependent posttranscriptional silencing of SOCS2
- (2018) Mengnuo Chen et al. HEPATOLOGY
- Targeting Gas6/TAM in cancer cells and tumor microenvironment
- (2018) Guiling Wu et al. Molecular Cancer
- PSPC1 mediates TGF-β1 autocrine signalling and Smad2/3 target switching to promote EMT, stemness and metastasis
- (2018) Hsi-Wen Yeh et al. NATURE CELL BIOLOGY
- Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation
- (2018) Huilin Huang et al. NATURE CELL BIOLOGY
- ISG15 in antiviral immunity and beyond
- (2018) Yi-Chieh Perng et al. NATURE REVIEWS MICROBIOLOGY
- Bispecific antibodies for cancer therapy: A review
- (2018) Anuradha Krishnamurthy et al. PHARMACOLOGY & THERAPEUTICS
- TGF-β induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression
- (2018) Silvia Ottaviani et al. Nature Communications
- Targeting stromal remodeling and cancer stem cell plasticity overcomes chemoresistance in triple negative breast cancer
- (2018) Aurélie S. Cazet et al. Nature Communications
- Carcinoma-associated fibroblasts promote the stemness and chemoresistance of colorectal cancer by transferring exosomal lncRNA H19
- (2018) Jing Ren et al. Theranostics
- Transcriptional Regulation in Prostate Cancer
- (2018) David P. Labbé et al. Cold Spring Harbor Perspectives in Medicine
- How to Hit Mesenchymal Stromal Cells and Make the Tumor Microenvironment Immunostimulant Rather Than Immunosuppressive
- (2018) Alessandro Poggi et al. Frontiers in Immunology
- Molecular iodine inhibits the expression of stemness markers on cancer stem-like cells of established cell lines derived from cervical cancer
- (2018) Gabriele Davide Bigoni-Ordóñez et al. BMC CANCER
- Emerging roles of Myc in stem cell biology and novel tumor therapies
- (2018) Go J. Yoshida JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Mogamulizumab versus vorinostat in previously treated cutaneous T-cell lymphoma (MAVORIC): an international, open-label, randomised, controlled phase 3 trial
- (2018) Youn H Kim et al. LANCET ONCOLOGY
- Breast cancer stem cells: Features, key drivers and treatment options
- (2018) Jürgen Dittmer SEMINARS IN CANCER BIOLOGY
- ALDH as a Stem Cell marker in solid tumors
- (2018) E Mariel Toledo-Guzman et al. Current Stem Cell Research & Therapy
- Venetoclax combined with decitabine or azacitidine in treatment-naive, elderly patients with acute myeloid leukemia
- (2018) Courtney D. DiNardo et al. BLOOD
- ADAR3 expression is an independent prognostic factor in lower-grade diffuse gliomas and positively correlated with the editing level of GRIA2Q607R
- (2018) Ying Zhang et al. Cancer Cell International
- Epithelial-Mesenchymal Transition Directs Stem Cell Polarity via Regulation of Mitofusin
- (2018) Meng-Ju Wu et al. Cell Metabolism
- CD123 expression patterns and selective targeting with a CD123-specific antibody-drug conjugate (IMGN632) in acute lymphoblastic leukemia
- (2018) Evgeniya Angelova et al. HAEMATOLOGICA
- Cancer-associated fibroblasts promote the stemness of CD24+ liver cells via paracrine signaling
- (2018) Yawen Li et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Randomized comparison of low dose cytarabine with or without glasdegib in patients with newly diagnosed acute myeloid leukemia or high-risk myelodysplastic syndrome
- (2018) Jorge E. Cortes et al. LEUKEMIA
- Translational control of tumor immune escape via the eIF4F–STAT1–PD-L1 axis in melanoma
- (2018) Michaël Cerezo et al. NATURE MEDICINE
- Turning foes to friends: targeting cancer-associated fibroblasts
- (2018) Xueman Chen et al. NATURE REVIEWS DRUG DISCOVERY
- MSI1 associates glioblastoma radioresistance via homologous recombination repair, tumor invasion and cancer stem-like cell properties
- (2018) Jang-Chun Lin et al. RADIOTHERAPY AND ONCOLOGY
- Prostate Stem Cells and Cancer Stem Cells
- (2018) Jia J. Li et al. Cold Spring Harbor Perspectives in Medicine
- ROS and the DNA damage response in cancer
- (2018) Upadhyayula Sai Srinivas et al. Redox Biology
- The STAT3/Slug Axis Enhances Radiation-Induced Tumor Invasion and Cancer Stem-like Properties in Radioresistant Glioblastoma
- (2018) Jang-Chun Lin et al. Cancers
- Cancer stem cell impact on clinical oncology
- (2018) Mariel E Toledo-Guzmán et al. World Journal of Stem Cells
- Lung cancer stem cells: origin, features, maintenance mechanisms and therapeutic targeting
- (2018) Win Sen Heng et al. BIOCHEMICAL PHARMACOLOGY
- Novel tumor-suppressor function of KLF4 in pediatric T-cell acute lymphoblastic leukemia
- (2017) Ye Shen et al. EXPERIMENTAL HEMATOLOGY
- SENP1 promotes hypoxia-induced cancer stemness by HIF-1α deSUMOylation and SENP1/HIF-1α positive feedback loop
- (2017) Chun-Ping Cui et al. GUT
- Chronic inflammation-elicited liver progenitor cell conversion to liver cancer stem cell with clinical significance
- (2017) Xiao-Feng Li et al. HEPATOLOGY
- Epithelial-mesenchymal transition and cancer stem cell-like phenotype induced by Twist1 contribute to acquired resistance to irinotecan in colon cancer
- (2017) Yong Yang et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Canonical and non-canonical WNT signaling in cancer stem cells and their niches: Cellular heterogeneity, omics reprogramming, targeted therapy and tumor plasticity (Review)
- (2017) Masaru Katoh INTERNATIONAL JOURNAL OF ONCOLOGY
- Up-regulation of glycolysis promotes the stemness and EMT phenotypes in gemcitabine-resistant pancreatic cancer cells
- (2017) Hengqiang Zhao et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Subcellular localisation of the stem cell markers OCT4, SOX2, NANOG, KLF4 and c-MYC in cancer: a review
- (2017) Bede van Schaijik et al. JOURNAL OF CLINICAL PATHOLOGY
- Proteomic analysis of pancreatic cancer stem cells: Functional role of fatty acid synthesis and mevalonate pathways
- (2017) Jessica Brandi et al. Journal of Proteomics
- Notch signaling pathway networks in cancer metastasis: a new target for cancer therapy
- (2017) Li Li et al. MEDICAL ONCOLOGY
- Syndecan-1 is a novel molecular marker for triple negative inflammatory breast cancer and modulates the cancer stem cell phenotype via the IL-6/STAT3, Notch and EGFR signaling pathways
- (2017) Sherif Abdelaziz Ibrahim et al. Molecular Cancer
- Epigenetics in cancer stem cells
- (2017) Tan Boon Toh et al. Molecular Cancer
- MicroRNA-218 functions as a tumor suppressor in lung cancer by targeting IL-6/STAT3 and negatively correlates with poor prognosis
- (2017) Yan Yang et al. Molecular Cancer
- A novel mechanism of lncRNA and miRNA interaction: CCAT2 regulates miR-145 expression by suppressing its maturation process in colon cancer cells
- (2017) Yingjie Yu et al. Molecular Cancer
- Intra-tumor heterogeneity from a cancer stem cell perspective
- (2017) Pramudita R. Prasetyanti et al. Molecular Cancer
- Oct4 transcriptionally regulates the expression of long non-coding RNAs NEAT1 and MALAT1 to promote lung cancer progression
- (2017) Jayu Jen et al. Molecular Cancer
- Cancer stem cells revisited
- (2017) Eduard Batlle et al. NATURE MEDICINE
- KLF4-dependent perivascular cell plasticity mediates pre-metastatic niche formation and metastasis
- (2017) Meera Murgai et al. NATURE MEDICINE
- EMT, CSCs, and drug resistance: the mechanistic link and clinical implications
- (2017) Tsukasa Shibue et al. Nature Reviews Clinical Oncology
- MicroRNA therapeutics: towards a new era for the management of cancer and other diseases
- (2017) Rajesha Rupaimoole et al. NATURE REVIEWS DRUG DISCOVERY
- Oncostatin M promotes cancer cell plasticity through cooperative STAT3-SMAD3 signaling
- (2017) D J Junk et al. ONCOGENE
- Essential role of METTL3-mediated m6A modification in glioma stem-like cells maintenance and radioresistance
- (2017) A Visvanathan et al. ONCOGENE
- DNA methylation of the Fthl17 5’-upstream region regulates differential Fthl17 expression in lung cancer cells and germline stem cells
- (2017) Nana Aoki et al. PLoS One
- Mutational landscape of RNA-binding proteins in human cancers
- (2017) Yaseswini Neelamraju et al. RNA Biology
- The Role of Integrin α6 (CD49f) in Stem Cells: More than a Conserved Biomarker
- (2017) Paul H. Krebsbach et al. STEM CELLS AND DEVELOPMENT
- Deciphering the mRNP Code: RNA-Bound Determinants of Post-Transcriptional Gene Regulation
- (2017) Niels H. Gehring et al. TRENDS IN BIOCHEMICAL SCIENCES
- KLF4 is a tumor suppressor in anaplastic meningioma stem-like cells and human meningiomas
- (2017) Hailiang Tang et al. Journal of Molecular Cell Biology
- Osteopontin production by TM4SF4 signaling drives a positive feedback autocrine loop with the STAT3 pathway to maintain cancer stem cell-like properties in lung cancer cells
- (2017) Soo Im Choi et al. Oncotarget
- Combinatorial effects of an epigenetic inhibitor and ionizing radiation contribute to targeted elimination of pancreatic cancer stem cell
- (2017) Hyun-Mi Kwon et al. Oncotarget
- Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted Therapies in the Absence of Mutation
- (2017) Andrea E. Calvert et al. Cell Reports
- Inhibition of KLF4 by Statins Reverses Adriamycin-Induced Metastasis and Cancer Stemness in Osteosarcoma Cells
- (2017) Yangling Li et al. Stem Cell Reports
- WNT antagonists exhibit unique combinatorial antitumor activity with taxanes by potentiating mitotic cell death
- (2017) Marcus M. Fischer et al. Science Advances
- Roles of microRNAs and RNA-Binding Proteins in the Regulation of Colorectal Cancer Stem Cells
- (2017) Junko Mukohyama et al. Cancers
- Musashi-1 promotes a cancer stem cell lineage and chemoresistance in colorectal cancer cells
- (2017) Guang-Yuh Chiou et al. Scientific Reports
- Cancer Stem Cells: Basic Concepts and Therapeutic Implications
- (2016) Dany Nassar et al. Annual Review of Pathology-Mechanisms of Disease
- Evolution of acute myelogenous leukemia stem cell properties after treatment and progression
- (2016) T.-C. Ho et al. BLOOD
- Epigenetic Perturbations by Arg882-Mutated DNMT3A Potentiate Aberrant Stem Cell Gene-Expression Program and Acute Leukemia Development
- (2016) Rui Lu et al. CANCER CELL
- Ovarian Cancer Chemoresistance Relies on the Stem Cell Reprogramming Factor PBX1
- (2016) Jin-Gyoung Jung et al. CANCER RESEARCH
- Hypoxia‐inducible factors: coupling glucose metabolism and redox regulation with induction of the breast cancer stem cell phenotype
- (2016) Gregg L Semenza EMBO JOURNAL
- ADAR-Mediated RNA Editing Predicts Progression and Prognosis of Gastric Cancer
- (2016) Tim Hon Man Chan et al. GASTROENTEROLOGY
- Octamer 4/microRNA-1246 signaling axis drives Wnt/β-catenin activation in liver cancer stem cells
- (2016) Stella Chai et al. HEPATOLOGY
- Cancer stem cells in moderately differentiated oral tongue squamous cell carcinoma
- (2016) Ranui Baillie et al. JOURNAL OF CLINICAL PATHOLOGY
- Cancer stem cell metabolism: a potential target for cancer therapy
- (2016) Abhijeet Deshmukh et al. Molecular Cancer
- KLF4 Suppresses Tumor Formation in Genetic and Pharmacological Mouse Models of Colonic Tumorigenesis
- (2016) A. M. Ghaleb et al. MOLECULAR CANCER RESEARCH
- Targeting renal cell carcinoma with a HIF-2 antagonist
- (2016) Wenfang Chen et al. NATURE
- On-target efficacy of a HIF-2α antagonist in preclinical kidney cancer models
- (2016) Hyejin Cho et al. NATURE
- The Hippo pathway in intestinal regeneration and disease
- (2016) Audrey W. Hong et al. Nature Reviews Gastroenterology & Hepatology
- Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m6A-demethylation of NANOG mRNA
- (2016) Chuanzhao Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TGF-β Family Signaling in the Control of Cell Proliferation and Survival
- (2016) Yun Zhang et al. Cold Spring Harbor Perspectives in Biology
- TGF-β and the TGF-β Family: Context-Dependent Roles in Cell and Tissue Physiology
- (2016) Masato Morikawa et al. Cold Spring Harbor Perspectives in Biology
- The transcription factor RUNX2 regulates receptor tyrosine kinase expression in melanoma
- (2016) Rajeev K. Boregowda et al. Oncotarget
- Emerging functions of the Quaking RNA-binding proteins and link to human diseases
- (2016) Lama Darbelli et al. Wiley Interdisciplinary Reviews-RNA
- H19 Noncoding RNA, an Independent Prognostic Factor, Regulates Essential Rb-E2F and CDK8-β-Catenin Signaling in Colorectal Cancer
- (2016) Masahisa Ohtsuka et al. EBioMedicine
- Hypoxia, Epithelial-Mesenchymal Transition, and TET-Mediated Epigenetic Changes
- (2016) Shih-Han Kao et al. Journal of Clinical Medicine
- Osteopontin—A Master Regulator of Epithelial-Mesenchymal Transition
- (2016) Anai Kothari et al. Journal of Clinical Medicine
- Targeting SOX2 as a Therapeutic Strategy in Glioblastoma
- (2016) Laura Garros-Regulez et al. Frontiers in Oncology
- Inhibition of Fatty Acid Synthase Decreases Expression of Stemness Markers in Glioma Stem Cells
- (2016) Yuki Yasumoto et al. PLoS One
- The H3K4-Methyl Epigenome Regulates Leukemia Stem Cell Oncogenic Potential
- (2015) Stephen H.K. Wong et al. CANCER CELL
- The Genomic Landscape and Clinical Relevance of A-to-I RNA Editing in Human Cancers
- (2015) Leng Han et al. CANCER CELL
- KLF4 regulates adult lung tumor-initiating cells and represses K-Ras-mediated lung cancer
- (2015) T Yu et al. CELL DEATH AND DIFFERENTIATION
- Downregulation of lncRNA-MALAT1 Affects Proliferation and the Expression of Stemness Markers in Glioma Stem Cell Line SHG139S
- (2015) Yong Han et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Molecular Pathways: Novel Approaches for Improved Therapeutic Targeting of Hedgehog Signaling in Cancer Stem Cells
- (2015) Verline Justilien et al. CLINICAL CANCER RESEARCH
- UTX inhibits EMT-induced breast CSC properties by epigenetic repression of EMT genes in cooperation with LSD1 and HDAC1
- (2015) H.-J. Choi et al. EMBO REPORTS
- Cancer stem-like cells of ovarian clear cell carcinoma are enriched in the ALDH-high population associated with an accelerated scavenging system in reactive oxygen species
- (2015) T. Mizuno et al. GYNECOLOGIC ONCOLOGY
- Bmi1 Drives Stem-Like Properties and is Associated with Migration, Invasion, and Poor Prognosis in Tongue Squamous Cell Carcinoma
- (2015) Qianting He et al. International Journal of Biological Sciences
- Long Noncoding RNA MALAT-1 Enhances Stem Cell-Like Phenotypes in Pancreatic Cancer Cells
- (2015) Feng Jiao et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- MicroRNA-34a regulates epithelial-mesenchymal transition and cancer stem cell phenotype of head and neck squamous cell carcinoma in vitro
- (2015) ZHIFENG SUN et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Coexpression of gene Oct4 and Nanog initiates stem cell characteristics in hepatocellular carcinoma and promotes epithelial-mesenchymal transition through activation of Stat3/Snail signaling
- (2015) Xin Yin et al. Journal of Hematology & Oncology
- Targeting Notch, Hedgehog and Wnt pathways in cancer stem cells: clinical update
- (2015) Naoko Takebe et al. Nature Reviews Clinical Oncology
- PAR1 inhibition suppresses the self-renewal and growth of A2B5-defined glioma progenitor cells and their derived gliomas in vivo
- (2015) R Auvergne et al. ONCOGENE
- Inhibition of c-Myc by let-7b mimic reverses mutidrug resistance in gastric cancer cells
- (2015) XIAOJUN YANG et al. ONCOLOGY REPORTS
- Antisense inhibition of microRNA-21 and microRNA-221 in tumor-initiating stem-like cells modulates tumorigenesis, metastasis, and chemotherapy resistance in pancreatic cancer
- (2015) Yue Zhao et al. Targeted Oncology
- MYC, Metabolism, and Cancer
- (2015) Z. E. Stine et al. Cancer Discovery
- Stem-Cell-like Properties and Epithelial Plasticity Arise as Stable Traits after Transient Twist1 Activation
- (2015) Johanna M. Schmidt et al. Cell Reports
- The Differential Expression of OCT4 Isoforms in Cervical Carcinoma
- (2015) Shao-Wen Li et al. PLoS One
- Blockade of Wnt/β-catenin signaling suppresses breast cancer metastasis by inhibiting CSC-like phenotype
- (2015) Gyu-Beom Jang et al. Scientific Reports
- Systemic effect of catumaxomab in a patient with metastasized colorectal cancer: a case report
- (2014) Angelika Bezan et al. BMC CANCER
- The aryl hydrocarbon receptor ligand omeprazole inhibits breast cancer cell invasion and metastasis
- (2014) Un-Ho Jin et al. BMC CANCER
- Intra- and postoperative catumaxomab in patients with epithelial ovarian cancer: safety and two-year efficacy results from a multicentre, single-arm, phase II study
- (2014) J Sehouli et al. BRITISH JOURNAL OF CANCER
- Decitabine, a new star in epigenetic therapy: the clinical application and biological mechanism in solid tumors
- (2014) Jing Nie et al. CANCER LETTERS
- Abstract 1855: Regulation of proliferation of colon cancer cells by compounds affecting glycolysis including 3-bromopyruvate, 2-deoxyglucose and biguanides.
- (2014) Michael A. Lea et al. CANCER RESEARCH
- The Cancer Stem Cell Marker Aldehyde Dehydrogenase Is Required to Maintain a Drug-Tolerant Tumor Cell Subpopulation
- (2014) D. Raha et al. CANCER RESEARCH
- The Noncoding RNA Revolution—Trashing Old Rules to Forge New Ones
- (2014) Thomas R. Cech et al. CELL
- Dock-family exchange factors in cell migration and disease
- (2014) Gilles Gadea et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- Tumor-Associated Macrophages Produce Interleukin 6 and Signal via STAT3 to Promote Expansion of Human Hepatocellular Carcinoma Stem Cells
- (2014) Shanshan Wan et al. GASTROENTEROLOGY
- New and emerging HDAC inhibitors for cancer treatment
- (2014) Alison C. West et al. JOURNAL OF CLINICAL INVESTIGATION
- miR-106b modulates cancer stem cell characteristics through TGF-β/Smad signaling in CD44-positive gastric cancer cells
- (2014) Dayeon Yu et al. LABORATORY INVESTIGATION
- BIM upregulation and ROS-dependent necroptosis mediate the antitumor effects of the HDACi Givinostat and Sorafenib in Hodgkin lymphoma cell line xenografts
- (2014) S L Locatelli et al. LEUKEMIA
- Histone methyltransferase G9a and H3K9 dimethylation inhibit the self-renewal of glioma cancer stem cells
- (2014) Hong Tao et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Blocking PGE2-induced tumour repopulation abrogates bladder cancer chemoresistance
- (2014) Antonina V. Kurtova et al. NATURE
- SOX2 controls tumour initiation and cancer stem-cell functions in squamous-cell carcinoma
- (2014) Soufiane Boumahdi et al. NATURE
- A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages
- (2014) Haihui Lu et al. NATURE CELL BIOLOGY
- Roles of Wnt/β-catenin signaling in the gastric cancer stem cells proliferation and salinomycin treatment
- (2014) J Mao et al. Cell Death & Disease
- Sox2 Promotes Malignancy in Glioblastoma by Regulating Plasticity and Astrocytic Differentiation
- (2014) Artem D. Berezovsky et al. NEOPLASIA
- RAR 2 expression confers myeloma stem cell features
- (2013) Y. Yang et al. BLOOD
- Ablation of Fbxw7 Eliminates Leukemia-Initiating Cells by Preventing Quiescence
- (2013) Shoichiro Takeishi et al. CANCER CELL
- Knockdown of Oct4 and Nanog expression inhibits the stemness of pancreatic cancer cells
- (2013) Yuhua Lu et al. CANCER LETTERS
- miR-7 Suppresses Brain Metastasis of Breast Cancer Stem-Like Cells By Modulating KLF4
- (2013) H. Okuda et al. CANCER RESEARCH
- Metabolic regulation of cancer cell side population by glucose through activation of the Akt pathway
- (2013) P-P Liu et al. CELL DEATH AND DIFFERENTIATION
- Lin28: Primal Regulator of Growth and Metabolism in Stem Cells
- (2013) Ng Shyh-Chang et al. Cell Stem Cell
- Role of the IL-6-JAK1-STAT3-Oct-4 pathway in the conversion of non-stem cancer cells into cancer stem-like cells
- (2013) Seog-Young Kim et al. CELLULAR SIGNALLING
- Preclinical and Clinical Studies of Gamma Secretase Inhibitors with Docetaxel on Human Breast Tumors
- (2013) A. F. Schott et al. CLINICAL CANCER RESEARCH
- Reprogramming Metabolism with Metformin Improves Tumor Oxygenation and Radiotherapy Response
- (2013) V. E. Zannella et al. CLINICAL CANCER RESEARCH
- Sox2 promotes tamoxifen resistance in breast cancer cells
- (2013) Marco Piva et al. EMBO Molecular Medicine
- Cancer heterogeneity—a multifaceted view
- (2013) Felipe De Sousa E Melo et al. EMBO REPORTS
- Identification of brain tumour initiating cells using the stem cell marker aldehyde dehydrogenase
- (2013) Seung Ah Choi et al. EUROPEAN JOURNAL OF CANCER
- A disrupted RNA editing balance mediated by ADARs (Adenosine DeAminases that act on RNA) in human hepatocellular carcinoma
- (2013) Tim Hon Man Chan et al. GUT
- Mechanisms of Lin28-Mediated miRNA and mRNA Regulation—A Structural and Functional Perspective
- (2013) Florian Mayr et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The VHL tumor suppressor protein regulates tumorigenicity of U87-derived glioma stem-like cells by inhibiting the JAK/STAT signaling pathway
- (2013) HIROSHI KANNO et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Synergy against PML-RARa: targeting transcription, proteolysis, differentiation, and self-renewal in acute promyelocytic leukemia
- (2013) Guilherme Augusto dos Santos et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma
- (2013) Leilei Chen et al. NATURE MEDICINE
- Lin28 Induces Epithelial-to-Mesenchymal Transition and Stemness via Downregulation of Let-7a in Breast Cancer Cells
- (2013) Yujie Liu et al. PLoS One
- miR-EdiTar: a database of predicted A-to-I edited miRNA target sites
- (2012) Alessandro Laganà et al. BIOINFORMATICS
- miRNA-21 is developmentally regulated in mouse brain and is co-expressed with SOX2 in glioma
- (2012) Jelena Põlajeva et al. BMC CANCER
- ALDH-positive lung cancer stem cells confer resistance to epidermal growth factor receptor tyrosine kinase inhibitors
- (2012) Cheng-Po Huang et al. CANCER LETTERS
- CCL2 Mediates Cross-talk between Cancer Cells and Stromal Fibroblasts That Regulates Breast Cancer Stem Cells
- (2012) A. Tsuyada et al. CANCER RESEARCH
- FoxM1 and Wnt/ -Catenin Signaling in Glioma Stem Cells
- (2012) A. Gong et al. CANCER RESEARCH
- Distinct microRNA Expression Profiles in Prostate Cancer Stem/Progenitor Cells and Tumor-Suppressive Functions of let-7
- (2012) C. Liu et al. CANCER RESEARCH
- MiR-21 regulates epithelial-mesenchymal transition phenotype and hypoxia-inducible factor-1α expression in third-sphere forming breast cancer stem cell-like cells
- (2012) Mingli Han et al. CANCER SCIENCE
- Cancer Epigenetics: From Mechanism to Therapy
- (2012) Mark A. Dawson et al. CELL
- Implications of Plasma Protein Binding for Pharmacokinetics and Pharmacodynamics of the -Secretase Inhibitor RO4929097
- (2012) J. Wu et al. CLINICAL CANCER RESEARCH
- Cell Plasticity and Heterogeneity in Cancer
- (2012) N. D. Marjanovic et al. CLINICAL CHEMISTRY
- Targeting the Unique Methylation Pattern of Androgen Receptor (AR) Promoter in Prostate Stem/Progenitor Cells with 5-Aza-2′-deoxycytidine (5-AZA) Leads to Suppressed Prostate Tumorigenesis
- (2012) Jing Tian et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Quiescence and attenuated DNA damage response promote survival of esophageal cancer stem cells
- (2012) Yulin Chen et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Epithelial-mesenchymal transition can suppress major attributes of human epithelial tumor-initiating cells
- (2012) Toni Celià-Terrassa et al. JOURNAL OF CLINICAL INVESTIGATION
- G9a interacts with Snail and is critical for Snail-mediated E-cadherin repression in human breast cancer
- (2012) Chenfang Dong et al. JOURNAL OF CLINICAL INVESTIGATION
- Phase I Study of RO4929097, a Gamma Secretase Inhibitor of Notch Signaling, in Patients With Refractory Metastatic or Locally Advanced Solid Tumors
- (2012) Anthony W. Tolcher et al. JOURNAL OF CLINICAL ONCOLOGY
- Histone Lysine Methylation Dynamics: Establishment, Regulation, and Biological Impact
- (2012) Joshua C. Black et al. MOLECULAR CELL
- Landscape of transcription in human cells
- (2012) Sarah Djebali et al. NATURE
- A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance
- (2012) Keisuke Ito et al. NATURE MEDICINE
- A Double-Blind, Placebo-Controlled Trial of Ruxolitinib for Myelofibrosis
- (2012) Srdan Verstovsek et al. NEW ENGLAND JOURNAL OF MEDICINE
- Efficacy and Safety of Vismodegib in Advanced Basal-Cell Carcinoma
- (2012) Aleksandar Sekulic et al. NEW ENGLAND JOURNAL OF MEDICINE
- Targeted silencing of the oncogenic transcription factor SOX2 in breast cancer
- (2012) Sabine Stolzenburg et al. NUCLEIC ACIDS RESEARCH
- Acquired cancer stem cell phenotypes through Oct4-mediated dedifferentiation
- (2012) S M Kumar et al. ONCOGENE
- Frequent Amplification of CENPF, GMNN and CDK13 Genes in Hepatocellular Carcinomas
- (2012) Hye-Eun Kim et al. PLoS One
- Snail1 Mediates Hypoxia-Induced Melanoma Progression
- (2011) Shujing Liu et al. AMERICAN JOURNAL OF PATHOLOGY
- Stem Cell Quiescence
- (2011) L. Li et al. CLINICAL CANCER RESEARCH
- Notch signaling: simplicity in design, versatility in function
- (2011) E. R. Andersson et al. DEVELOPMENT
- Direct reprogramming of stem cell properties in colon cancer cells by CD44
- (2011) Ying-Jhen Su et al. EMBO JOURNAL
- The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells
- (2011) Simone Brabletz et al. EMBO JOURNAL
- Expression profile of embryonic stem cell-associated genes Oct4, Sox2 and Nanog in human gliomas
- (2011) Yuji Guo et al. HISTOPATHOLOGY
- Metabolic Alterations in Highly Tumorigenic Glioblastoma Cells
- (2011) Yunfei Zhou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Bone morphogenetic protein 7 in dormancy and metastasis of prostate cancer stem-like cells in bone
- (2011) Aya Kobayashi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Gastrointestinal stem cells in self-renewal and cancer
- (2011) S. Adelia Lin et al. JOURNAL OF GASTROENTEROLOGY
- Association of microRNA-21 expression with its targets, PDCD4 and TIMP3, in pancreatic ductal adenocarcinoma
- (2011) Yuichi Nagao et al. MODERN PATHOLOGY
- Pharmacologic disruption of Polycomb Repressive Complex 2 inhibits tumorigenicity and tumor progression in prostate cancer
- (2011) Francesco Crea et al. Molecular Cancer
- Cells of origin in cancer
- (2011) Jane E. Visvader NATURE
- The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44
- (2011) Can Liu et al. NATURE MEDICINE
- Molecular control of endothelial cell behaviour during blood vessel morphogenesis
- (2011) Shane P. Herbert et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Hypoxia-induced Jagged2 promotes breast cancer metastasis and self-renewal of cancer stem-like cells
- (2011) F Xing et al. ONCOGENE
- Sox2 expression in breast tumours and activation in breast cancer stem cells
- (2011) O Leis et al. ONCOGENE
- Cancer Stem Cell Tumor Model Reveals Invasive Morphology and Increased Phenotypical Heterogeneity
- (2010) A. Sottoriva et al. CANCER RESEARCH
- A Temporarily Distinct Subpopulation of Slow-Cycling Melanoma Cells Is Required for Continuous Tumor Growth
- (2010) Alexander Roesch et al. CELL
- Targeting Hedgehog -- a Cancer Stem Cell Pathway
- (2010) A. A. Merchant et al. CLINICAL CANCER RESEARCH
- Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells
- (2010) Lucia Ricci-Vitiani et al. NATURE
- Bmi1 is essential in Twist1-induced epithelial–mesenchymal transition
- (2010) Muh-Hwa Yang et al. NATURE CELL BIOLOGY
- Wnt activity defines colon cancer stem cells and is regulated by the microenvironment
- (2010) Louis Vermeulen et al. NATURE CELL BIOLOGY
- Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia
- (2010) Michael G Kharas et al. NATURE MEDICINE
- Pluripotency factors Lin28 and Oct4 identify a sub-population of stem cell-like cells in ovarian cancer
- (2010) S Peng et al. ONCOGENE
- Oct4 and Nanog Expression Is Associated With Early Stages of Pancreatic Carcinogenesis
- (2010) Jing Wen et al. PANCREAS
- Regulation of autophagy by ROS: physiology and pathology
- (2010) Ruth Scherz-Shouval et al. TRENDS IN BIOCHEMICAL SCIENCES
- MicroRNA-34a Inhibits Glioblastoma Growth by Targeting Multiple Oncogenes
- (2009) Y. Li et al. CANCER RESEARCH
- Association of reactive oxygen species levels and radioresistance in cancer stem cells
- (2009) Maximilian Diehn et al. NATURE
- The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs
- (2009) Ulrich Wellner et al. NATURE CELL BIOLOGY
- SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas
- (2009) Adam J Bass et al. NATURE GENETICS
- Tumour-initiating cells: challenges and opportunities for anticancer drug discovery
- (2009) Bin-Bing S. Zhou et al. NATURE REVIEWS DRUG DISCOVERY
- Lin28-mediated post-transcriptional regulation of Oct4 expression in human embryonic stem cells
- (2009) Caihong Qiu et al. NUCLEIC ACIDS RESEARCH
- Pbx1 is a downstream target of Evi-1 in hematopoietic stem/progenitors and leukemic cells
- (2009) M Shimabe et al. ONCOGENE
- p21CIP1attenuates Ras- and c-Myc-dependent breast tumor epithelial mesenchymal transition and cancer stem cell-like gene expression in vivo
- (2009) Manran Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MicroRNAs in Cancer
- (2008) Yong Sun Lee et al. Annual Review of Pathology-Mechanisms of Disease
- ASB2 targets filamins A and B to proteasomal degradation
- (2008) M. L. Heuze et al. BLOOD
- Oncogenic Kras-induced leukemogeneis: hematopoietic stem cells as the initial target and lineage-specific progenitors as the potential targets for final leukemic transformation
- (2008) J. Zhang et al. BLOOD
- MicroRNA Microarray Identifies Let-7i as a Novel Biomarker and Therapeutic Target in Human Epithelial Ovarian Cancer
- (2008) N. Yang et al. CANCER RESEARCH
- Targeting Cancer Stem Cells through L1CAM Suppresses Glioma Growth
- (2008) S. Bao et al. CANCER RESEARCH
- The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
- (2008) Sendurai A. Mani et al. CELL
- Preferential Physical and Functional Interaction of Pregnane X Receptor with the SMRT Isoform
- (2008) C.-W. Li et al. MOLECULAR PHARMACOLOGY
- Crypt stem cells as the cells-of-origin of intestinal cancer
- (2008) Nick Barker et al. NATURE
- Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity
- (2008) L. Vermeulen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Notch signaling mediates hypoxia-induced tumor cell migration and invasion
- (2008) C. Sahlgren et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now