METTL3 facilitates tumor progression via an m6A-IGF2BP2-dependent mechanism in colorectal carcinoma
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Title
METTL3 facilitates tumor progression via an m6A-IGF2BP2-dependent mechanism in colorectal carcinoma
Authors
Keywords
Colorectal cancer, N<sup>6</sup>-methyladenosine (m<sup>6</sup>A), METTL3, SOX2, IGF2BP2
Journal
Molecular Cancer
Volume 18, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-06-24
DOI
10.1186/s12943-019-1038-7
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Note: Only part of the references are listed.- HBXIP-elevated methyltransferase METTL3 promotes the progression of breast cancer via inhibiting tumor suppressor let-7g
- (2018) Xiaoli Cai et al. CANCER LETTERS
- ME1 Regulates NADPH Homeostasis to Promote Gastric Cancer Growth and Metastasis
- (2018) Yun-Xin Lu et al. CANCER RESEARCH
- RNA N6-methyladenosine modification in cancers: current status and perspectives
- (2018) Xiaolan Deng et al. CELL RESEARCH
- METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m 6 A Modification
- (2018) Hengyou Weng et al. Cell Stem Cell
- Role of N 6 -methyladenosine modification in cancer
- (2018) Xiaolan Deng et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- RNA N6-methyladenosine methyltransferase-like 3 promotes liver cancer progression through YTHDF2-dependent posttranscriptional silencing of SOCS2
- (2018) Mengnuo Chen et al. HEPATOLOGY
- Modified XELIRI (capecitabine plus irinotecan) versus FOLFIRI (leucovorin, fluorouracil, and irinotecan), both either with or without bevacizumab, as second-line therapy for metastatic colorectal cancer (AXEPT): a multicentre, open-label, randomised, non-inferiority, phase 3 trial
- (2018) Rui-Hua Xu et al. LANCET ONCOLOGY
- Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation
- (2018) Huilin Huang et al. NATURE CELL BIOLOGY
- OUP accepted manuscript
- (2018) JNCI-Journal of the National Cancer Institute
- A distinct role for Lgr5+ stem cells in primary and metastatic colon cancer
- (2017) Felipe de Sousa e Melo et al. NATURE
- RNA m6A methylation regulates the ultraviolet-induced DNA damage response
- (2017) Yang Xiang et al. NATURE
- Circulating tumour DNA methylation markers for diagnosis and prognosis of hepatocellular carcinoma
- (2017) Rui-hua Xu et al. NATURE MATERIALS
- The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells
- (2017) Ly P Vu et al. NATURE MEDICINE
- Essential role of METTL3-mediated m6A modification in glioma stem-like cells maintenance and radioresistance
- (2017) A Visvanathan et al. ONCOGENE
- NSPc1 promotes cancer stem cell self-renewal by repressing the synthesis of all-trans retinoic acid via targeting RDH16 in malignant glioma
- (2017) P-S Hu et al. ONCOGENE
- DNA methylation markers for diagnosis and prognosis of common cancers
- (2017) Xiaoke Hao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Epigenetic plasticity and the hallmarks of cancer
- (2017) William A. Flavahan et al. SCIENCE
- Rb1 and Trp53 cooperate to suppress prostate cancer lineage plasticity, metastasis, and antiandrogen resistance
- (2017) Sheng Yu Ku et al. SCIENCE
- m 6 A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells
- (2017) Qi Cui et al. Cell Reports
- METTL14 suppresses the metastatic potential of hepatocellular carcinoma by modulatingN6-methyladenosine-dependent primary MicroRNA processing
- (2016) Jin-zhao Ma et al. HEPATOLOGY
- The m 6 A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells
- (2016) Shuibin Lin et al. MOLECULAR CELL
- Redox Regulation of Stem-like Cells Though the CD44v-xCT Axis in Colorectal Cancer: Mechanisms and Therapeutic Implications
- (2016) Huai-Qiang Ju et al. Theranostics
- The RNA Binding Protein IMP2 Preserves Glioblastoma Stem Cells by Preventing let-7 Target Gene Silencing
- (2016) Nils Degrauwe et al. Cell Reports
- N6-methyladenosine Modulates Messenger RNA Translation Efficiency
- (2015) Xiao Wang et al. CELL
- m6A RNA Methylation Is Regulated by MicroRNAs and Promotes Reprogramming to Pluripotency
- (2015) Tong Chen et al. Cell Stem Cell
- Isorhapontigenin suppresses growth of patient-derived glioblastoma spheres through regulating miR-145/SOX2/cyclin D1 axis
- (2015) Zhou Xu et al. NEURO-ONCOLOGY
- The PRKCI and SOX2 Oncogenes Are Coamplified and Cooperate to Activate Hedgehog Signaling in Lung Squamous Cell Carcinoma
- (2014) Verline Justilien et al. CANCER CELL
- SOX2 controls tumour initiation and cancer stem-cell functions in squamous-cell carcinoma
- (2014) Soufiane Boumahdi et al. NATURE
- RNA-Methylation-Dependent RNA Processing Controls the Speed of the Circadian Clock
- (2013) Jean-Michel Fustin et al. CELL
- N6-methyladenosine-dependent regulation of messenger RNA stability
- (2013) Xiao Wang et al. NATURE
- Transcriptome-wide mapping of N6-methyladenosine by m6A-seq based on immunocapturing and massively parallel sequencing
- (2013) Dan Dominissini et al. Nature Protocols
- Imp2 controls oxidative phosphorylation and is crucial for preserving glioblastoma cancer stem cells
- (2012) M. Janiszewska et al. GENES & DEVELOPMENT
- SOX2 has a crucial role in the lineage determination and proliferation of mesenchymal stem cells through Dickkopf-1 and c-MYC
- (2011) S B Park et al. CELL DEATH AND DIFFERENTIATION
- Colon Cancer Stem Cells: Promise of Targeted Therapy
- (2010) Matilde Todaro et al. GASTROENTEROLOGY
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