HIST2H2BF Potentiates the Propagation of Cancer Stem Cells via Notch Signaling to Promote Malignancy and Liver Metastasis in Colorectal Carcinoma

The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer

(2021) Arafath K. Najumudeen et al.   NATURE GENETICS

Quantifying single-cell ERK dynamics in colorectal cancer organoids reveals EGFR as an amplifier of oncogenic MAPK pathway signalling

(2021) Bas Ponsioen et al.   NATURE CELL BIOLOGY

Laminin 521 enhances self-renewal via STAT3 activation and promotes tumor progression in colorectal cancer

(2020) Yan Qin et al.   CANCER LETTERS

Blocking histone methyltransferase SETDB1 inhibits tumorigenesis and enhances cetuximab sensitivity in colorectal cancer

(2020) Zhenlin Hou et al.   CANCER LETTERS

Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer

(2020) Arianna Fumagalli et al.   Cell Stem Cell

Rare driver mutations in head and neck squamous cell carcinomas converge on NOTCH signaling

(2020) Sampath K. Loganathan et al.   SCIENCE

Regenerative Reprogramming of the Intestinal Stem Cell State via Hippo Signaling Suppresses Metastatic Colorectal Cancer

(2020) Priscilla Cheung et al.   Cell Stem Cell

TP63, SOX2, and KLF5 Establish a Core Regulatory Circuitry That Controls Epigenetic and Transcription Patterns in Esophageal Squamous Cell Carcinoma Cell Lines

(2020) Yan-Yi Jiang et al.   GASTROENTEROLOGY

Hypoxia-driven epigenetic regulation in cancer progression: A focus on histone methylation and its modifying enzymes

(2020) Iljin Kim et al.   CANCER LETTERS

Poly( ADP ‐ribose) glycohydrolase silencing‐mediated H2B expression inhibits benzo(a)pyrene‐induced carcinogenesis

(2020) Zhuoying Zeng et al.   ENVIRONMENTAL TOXICOLOGY

DCLK1, a putative novel stem cell marker in human cholangiocarcinoma

(2020) Lorenzo Nevi et al.   HEPATOLOGY

DNA Methylation of CNRIP1 Promotes Pathogenesis of Intrahepatic Cholangiocarcinoma Through Suppressing Parkin‐Dependent PKM2 Ubiquitination

(2020) Diyu Chen et al.   HEPATOLOGY

Stromal Cells Exhibit Prevalent Genetic Aberrations in Colorectal Cancer

(2020) Kathleen M. McAndrews et al.   CANCER CELL

DNA methylation profiling of human hepatocarcinogenesis

(2020) Gabriela Hernandez‐Meza et al.   HEPATOLOGY

Overexpression of SMAD7 activates the YAP/NOTCH cascade and promotes liver carcinogenesis in mice and humans

(2020) Haichuan Wang et al.   HEPATOLOGY

Unveiling role of sphingosine-1-phosphate receptor 2 as a brake of epithelial stem cell proliferation and a tumor suppressor in colorectal cancer

(2020) Luciana Petti et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Targeting Notch in oncology: the path forward

(2020) Samarpan Majumder et al.   NATURE REVIEWS DRUG DISCOVERY

Therapeutic targeting of the oncogenic Wnt signaling pathway for treating colorectal cancer and other colonic disorders

(2020) Michal Caspi et al.   ADVANCED DRUG DELIVERY REVIEWS

Identification of a pan-gamma-secretase inhibitor response signature for notch-driven cholangiocarcinoma

(2019) Colm J. O'Rourke et al.   HEPATOLOGY

Colon Cancer: Epithelial Notch Signaling Recruits Neutrophils to Drive Metastasis

(2019) Jürgen Ruland   CANCER CELL

A Novel Prognostic DNA Methylation Panel for Colorectal Cancer

(2019) Hsin-Hua Chung et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Metallopanstimulin-1 (MPS-1) mediates the promotion effect of leptin on colorectal cancer through activation of JNK/c-Jun signaling pathway

(2019) Dongxing Cao et al.   Cell Death & Disease

Kinesin family member 15 promotes cancer stem cell phenotype and malignancy via reactive oxygen species imbalance in hepatocellular carcinoma

(2019) Qing Li et al.   CANCER LETTERS

Modulation of biliary cancer chemo‐resistance through microRNA‐mediated rewiring of the expansion of CD133+ cells

(2019) Pietro Carotenuto et al.   HEPATOLOGY

Network biology elucidates metastatic colon cancer mechanisms

(2015) Inna Kuperstein et al.   CELL CYCLE

Small molecules intercept Notch signaling and the early secretory pathway

(2013) Andreas Krämer et al.   Nature Chemical Biology