Sox2 promotes tamoxifen resistance in breast cancer cells

Lgr4 regulates mammary gland development and stem cell activity through the pluripotency transcription factor Sox2

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Pharmacological Inhibition of the Wnt Acyltransferase PORCN Prevents Growth of WNT-Driven Mammary Cancer

(2012) K. D. Proffitt et al.   CANCER RESEARCH

Activation Status of Wnt/ß-Catenin Signaling in Normal and Neoplastic Breast Tissues: Relationship to HER2/neu Expression in Human and Mouse

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ID4 Imparts Chemoresistance and Cancer Stemness to Glioma Cells by Derepressing miR-9*-Mediated Suppression of SOX2

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SOX2 promotes tumorigenesis and increases the anti-apoptotic property of human prostate cancer cell

(2011) X. Jia et al.   Journal of Molecular Cell Biology

Effects of estrogen on the proportion of stem cells in the breast

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Biological and Molecular Heterogeneity of Breast Cancers Correlates with Their Cancer Stem Cell Content

(2010) Salvatore Pece et al.   CELL

Wnt Proteins Are Self-Renewal Factors for Mammary Stem Cells and Promote Their Long-Term Expansion in Culture

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Wnt and mammary stem cells: hormones cannot fly wingless

(2010) Kevin Roarty et al.   CURRENT OPINION IN PHARMACOLOGY

Function Follows Form: Defining Mammary Stem Cells

(2010) M. d. Vivanco   Science Translational Medicine

Distinct Roles for Wnt-4 and Wnt-11 During Retinoic Acid-Induced Neuronal Differentiation

(2010) Carina Elizalde et al.   STEM CELLS

Breast Cancer Cell Lines Contain Functional Cancer Stem Cells with Metastatic Capacity and a Distinct Molecular Signature

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Small molecule–mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer

(2009) Baozhi Chen et al.   Nature Chemical Biology

HOXB9, a gene overexpressed in breast cancer, promotes tumorigenicity and lung metastasis

(2009) T. Hayashida et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Therapeutic Implications of the Cancer Stem Cell Hypothesis

(2009) Maximilian Diehn et al.   SEMINARS IN RADIATION ONCOLOGY

A Gene Expression Signature that Can Predict the Recurrence of Tamoxifen-Treated Primary Breast Cancer

(2008) M. Chanrion et al.   CLINICAL CANCER RESEARCH

The Molecular Mechanism Governing the Oncogenic Potential of SOX2 in Breast Cancer

(2008) Yupeng Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intrinsic Resistance of Tumorigenic Breast Cancer Cells to Chemotherapy

(2008) X. Li et al.   JNCI-Journal of the National Cancer Institute

An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors

(2008) Ittai Ben-Porath et al.   NATURE GENETICS

BRCA1 regulates human mammary stem/progenitor cell fate

(2008) S. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA