YTHDF2 facilitates UBXN1 mRNA decay by recognizing METTL3-mediated m6A modification to activate NF-κB and promote the malignant progression of glioma

R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis

(2021) Ying Qing et al.   MOLECULAR CELL

EGFR/SRC/ERK-stabilized YTHDF2 promotes cholesterol dysregulation and invasive growth of glioblastoma

(2021) Runping Fang et al.   Nature Communications

Chinese Glioma Genome Atlas (CGGA): A Comprehensive Resource with Functional Genomic Data from Chinese Gliomas

(2021) Zheng Zhao et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

METTL3 enhances the stability of MALAT1 with the assistance of HuR via m6A modification and activates NF-κB to promote the malignant progression of IDH-wildtype glioma

(2021) Yu-Zhou Chang et al.   CANCER LETTERS

Emerging role of RNA methyltransferase METTL3 in gastrointestinal cancer

(2020) Qiang Wang et al.   Journal of Hematology & Oncology

Role of CX3CR1 Signaling in Malignant Transformation of Gliomas

(2020) Sungho Lee et al.   NEURO-ONCOLOGY

YTHDF2 promotes the liver cancer stem cell phenotype and cancer metastasis by regulating OCT4 expression via m6A RNA methylation

(2020) Chuanzhao Zhang et al.   ONCOGENE

The molecular characteristics of spinal cord gliomas with or without H3 K27M mutation

(2020) Rui-Chao Chai et al.   Acta Neuropathologica Communications

RNA modifications in brain tumorigenesis

(2020) Albert Z. Huang et al.   Acta Neuropathologica Communications

MGMT genomic rearrangements contribute to chemotherapy resistance in gliomas

(2020) Barbara Oldrini et al.   Nature Communications

The RNA m6A reader YTHDF2 maintains oncogene expression and is a targetable dependency in glioblastoma stem cells

(2020) Deobrat Dixit et al.   Cancer Discovery

Transcriptional Characteristics of IDH-Wild Type Glioma Subgroups Highlight the Biological Processes Underlying Heterogeneity of IDH-Wild Type WHO Grade IV Gliomas

(2020) Yu-Zhou Chang et al.   Frontiers in Cell and Developmental Biology

Clinical practice guidelines for the management of adult diffuse gliomas

(2020) Tao Jiang et al.   CANCER LETTERS

Endoribonucleolytic Cleavage of m6A-Containing RNAs by RNase P/MRP Complex

(2019) Ok Hyun Park et al.   MOLECULAR CELL

m6A RNA methylation regulators contribute to malignant progression and have clinical prognostic impact in gliomas

(2019) Rui-Chao Chai et al.   Aging-US

Systematically characterize the clinical and biological significances of 1p19q genes in 1p/19q non-codeletion glioma

(2019) Rui-Chao Chai et al.   CARCINOGENESIS

Metascape provides a biologist-oriented resource for the analysis of systems-level datasets

(2019) Yingyao Zhou et al.   Nature Communications

N6-methyladenosine Modulates Nonsense-mediated mRNA Decay in Human Glioblastoma

(2019) Fuxi Li et al.   CANCER RESEARCH

The interplay between m6A RNA methylation and noncoding RNA in cancer

(2019) Shuai Ma et al.   Journal of Hematology & Oncology

R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m 6 A/MYC/CEBPA Signaling

(2018) Rui Su et al.   CELL

Dynamic transcriptomic m6A decoration: writers, erasers, readers and functions in RNA metabolism

(2018) Ying Yang et al.   CELL RESEARCH

Somatostatin receptor 2A protein expression characterizes anaplastic oligodendrogliomas with favorable outcome

(2018) Romain Appay et al.   Acta Neuropathologica Communications

NF-κB, Mesenchymal Differentiation and Glioblastoma

(2018) Bakhtiar Yamini   Cells

Mutational Landscape of Secondary Glioblastoma Guides MET-Targeted Trial in Brain Tumor

(2018) Huimin Hu et al.   CELL

YTHDF2 suppresses cell proliferation and growth via destabilizing the EGFR mRNA in hepatocellular carcinoma

(2018) Li Zhong et al.   CANCER LETTERS

PLK4 is a determinant of temozolomide sensitivity through phosphorylation of IKBKE in glioblastoma

(2018) Zuoxin Zhang et al.   CANCER LETTERS

Essential role of METTL3-mediated m6A modification in glioma stem-like cells maintenance and radioresistance

(2017) A Visvanathan et al.   ONCOGENE

m 6 A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells

(2017) Qi Cui et al.   Cell Reports

An LXR-Cholesterol Axis Creates a Metabolic Co-Dependency for Brain Cancers

(2016) Genaro R. Villa et al.   CANCER CELL

Clonal evolution of glioblastoma under therapy

(2016) Jiguang Wang et al.   NATURE GENETICS

YTHDF2 destabilizes m6A-containing RNA through direct recruitment of the CCR4–NOT deadenylase complex

(2016) Hao Du et al.   Nature Communications

Uncoupling Nuclear Receptor LXR and Cholesterol Metabolism in Cancer

(2015) Fabiola Bovenga et al.   Cell Metabolism

Ubiquitin-associated Domain-containing Ubiquitin Regulatory X (UBX) Protein UBXN1 Is a Negative Regulator of Nuclear Factor κB (NF-κB) Signaling

(2015) Yu-Bo Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AQP5 is differentially regulated in astrocytes during metabolic and traumatic injuries

(2013) Rui Chao Chai et al.   GLIA

N6-methyladenosine-dependent regulation of messenger RNA stability

(2013) Xiao Wang et al.   NATURE

Genome-wide Repression of NF-κB Target Genes by Transcription Factor MIBP1 and Its Modulation by O -Linked β- N -Acetylglucosamine ( O -GlcNAc) Transferase

(2012) Yuji Iwashita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY