WNT antagonists exhibit unique combinatorial antitumor activity with taxanes by potentiating mitotic cell death

Wnt signaling in cancer

(2016) T Zhan et al.   ONCOGENE

Wnt-mediated protein stabilization ensures proper mitotic microtubule assembly and chromosome segregation

(2015) A. Stolz et al.   EMBO REPORTS

Targeting Wnts at the Source--New Mechanisms, New Biomarkers, New Drugs

(2015) B. Madan et al.   MOLECULAR CANCER THERAPEUTICS

β-catenin regulates c-Myc and CDKN1A expression in breast cancer cells

(2015) Jinhua Xu et al.   MOLECULAR CARCINOGENESIS

Tumorgrafts asIn VivoSurrogates for Women with Ovarian Cancer

(2014) S. John Weroha et al.   CLINICAL CANCER RESEARCH

Nek2 phosphorylates and stabilizes β-catenin at mitotic centrosomes downstream of Plk1

(2014) Bertrade C. Mbom et al.   MOLECULAR BIOLOGY OF THE CELL

Abstract B79: A first-in-human Phase 1 study of anti-cancer stem cell (CSC) agent OMP-54F28 (FZD8-Fc) targeting the WNT pathway in patients with advanced solid tumors.

(2014) D. C. Smith et al.   MOLECULAR CANCER THERAPEUTICS

An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control

(2014) H. Clevers et al.   SCIENCE

Cytotoxicity of Paclitaxel in Breast Cancer Is due to Chromosome Missegregation on Multipolar Spindles

(2014) L. M. Zasadil et al.   Science Translational Medicine

Increased Survival in Pancreatic Cancer with nab-Paclitaxel plus Gemcitabine

(2013) Daniel D. Von Hoff et al.   NEW ENGLAND JOURNAL OF MEDICINE

Evolving concepts in the management of drug resistant ovarian cancer: Dose dense chemotherapy and the reversal of clinical platinum resistance

(2012) David J. Pinato et al.   CANCER TREATMENT REVIEWS

Anti-DLL4 Has Broad Spectrum Activity in Pancreatic Cancer Dependent on Targeting DLL4-Notch Signaling in Both Tumor and Vasculature Cells

(2012) W.-C. Yen et al.   CLINICAL CANCER RESEARCH

Mitotic and mitogenic Wnt signalling

(2012) Christof Niehrs et al.   EMBO JOURNAL

The way Wnt works: Components and mechanism

(2012) Kenyi Saito-Diaz et al.   GROWTH FACTORS

Patients' Expectations about Effects of Chemotherapy for Advanced Cancer

(2012) Jane C. Weeks et al.   NEW ENGLAND JOURNAL OF MEDICINE

Wnt pathway inhibition via the targeting of Frizzled receptors results in decreased growth and tumorigenicity of human tumors

(2012) A. Gurney et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Paclitaxel efficacy and toxicity in older women with metastatic breast cancer: combined analysis of CALGB 9342 and 9840

(2011) S. M. Lichtman et al.   ANNALS OF ONCOLOGY

Paracrine and Autocrine Signals Induce and Maintain Mesenchymal and Stem Cell States in the Breast

(2011) Christina Scheel et al.   CELL

Characterization of the effects of cisplatin and carboplatin on cell cycle progression and DNA damage response activation in DNA polymerase eta-deficient human cells

(2011) Séverine Cruet-Hennequart et al.   CELL CYCLE

Tumor Engraftment in Nude Mice and Enrichment in Stroma- Related Gene Pathways Predict Poor Survival and Resistance to Gemcitabine in Patients with Pancreatic Cancer

(2011) I. Garrido-Laguna et al.   CLINICAL CANCER RESEARCH

Mitotic catastrophe: a mechanism for avoiding genomic instability

(2011) Ilio Vitale et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Dishevelled, a Wnt signalling component, is involved in mitotic progression in cooperation with Plk1

(2010) Koji Kikuchi et al.   EMBO JOURNAL

Genome remodelling in a basal-like breast cancer metastasis and xenograft

(2010) Li Ding et al.   NATURE

Cell Cycle Control of Wnt Receptor Activation

(2009) Gary Davidson et al.   DEVELOPMENTAL CELL

Elevating the frequency of chromosome mis-segregation as a strategy to kill tumor cells

(2009) Aniek Janssen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA