Cancer-associated fibroblasts promote the stemness of CD24+ liver cells via paracrine signaling

Targeting the IL-6/JAK/STAT3 signalling axis in cancer

(2018) Daniel E. Johnson et al.   Nature Reviews Clinical Oncology

Cancer-associated Fibroblast-derived IL-6 Promotes Head and Neck Cancer Progression via the Osteopontin-NF-kappa B Signaling Pathway

(2018) Xing Qin et al.   Theranostics

CD24 regulates cancer stem cell (CSC)-like traits and a panel of CSC-related molecules serves as a non-invasive urinary biomarker for the detection of bladder cancer

(2018) Akira Ooki et al.   BRITISH JOURNAL OF CANCER

STAT3 activation by leptin receptor is essential for TNBC stem cell maintenance

(2017) Praveena S Thiagarajan et al.   ENDOCRINE-RELATED CANCER

Selective targeted delivery of doxorubicin via conjugating to anti-CD24 antibody results in enhanced antitumor potency for hepatocellular carcinoma both in vitro and in vivo

(2017) Zhaoxiong Ma et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

miR-500a-3p promotes cancer stem cells properties via STAT3 pathway in human hepatocellular carcinoma

(2017) Chunlin Jiang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

STAT3-mediated upregulation of lncRNA HOXD-AS1 as a ceRNA facilitates liver cancer metastasis by regulating SOX4

(2017) Hui Wang et al.   Molecular Cancer

Hepatocyte Growth Factor, a Key Tumor-Promoting Factor in the Tumor Microenvironment

(2017) Benjamin Owusu et al.   Cancers

Cancer-associated fibroblasts promote hepatocellular carcinoma metastasis through chemokine-activated hedgehog and TGF-β pathways

(2016) Jiao Liu et al.   CANCER LETTERS

IL-6/STAT3 axis initiated CAFs via up-regulating TIMP-1 which was attenuated by acetylation of STAT3 induced by PCAF in HCC microenvironment

(2016) Xin Zheng et al.   CELLULAR SIGNALLING

Cancer-associated fibroblasts promote the progression of endometrial cancer via the SDF-1/CXCR4 axis

(2016) Fei Teng et al.   Journal of Hematology & Oncology

IL-6 pathway in the liver: From physiopathology to therapy

(2016) Dirk Schmidt-Arras et al.   JOURNAL OF HEPATOLOGY

Cancer-Associated Fibroblasts Regulate Tumor-Initiating Cell Plasticity in Hepatocellular Carcinoma through c-Met/FRA1/HEY1 Signaling

(2016) Eunice Yuen Ting Lau et al.   Cell Reports

Hepatocellular carcinoma

(2016) Josep M. Llovet et al.   Nature Reviews Disease Primers

FGF-1/-3/FGFR4 signaling in cancer-associated fibroblasts promotes tumor progression in colon cancer through Erk and MMP-7

(2015) Yu-Pan Bai et al.   CANCER SCIENCE

Tumor-Associated Macrophages Produce Interleukin 6 and Signal via STAT3 to Promote Expansion of Human Hepatocellular Carcinoma Stem Cells

(2014) Shanshan Wan et al.   GASTROENTEROLOGY

c-Met pathway promotes self-renewal and tumorigenecity of head and neck squamous cell carcinoma stem-like cell

(2014) Young Chang Lim et al.   ORAL ONCOLOGY

The IL-6–STAT3 axis mediates a reciprocal crosstalk between cancer-derived mesenchymal stem cells and neutrophils to synergistically prompt gastric cancer progression

(2014) Q Zhu et al.   Cell Death & Disease

Twist2 promotes self-renewal of liver cancer stem-like cells by regulating CD24

(2013) Allan Yi Liu et al.   CARCINOGENESIS

Cancer-associated fibroblasts might sustain the stemness of scirrhous gastric cancer cells via transforming growth factor-β signaling

(2013) Tsuyoshi Hasegawa et al.   INTERNATIONAL JOURNAL OF CANCER

Cancer stem cells in the development of liver cancer

(2013) Taro Yamashita et al.   JOURNAL OF CLINICAL INVESTIGATION

Met as a therapeutic target in HCC: Facts and hopes

(2013) Silvia Giordano et al.   JOURNAL OF HEPATOLOGY

Cancer-Associated Fibroblasts from Hepatocellular Carcinoma Promote Malignant Cell Proliferation by HGF Secretion

(2013) Chang-Chang Jia et al.   PLoS One

Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment

(2012) Douglas Hanahan et al.   CANCER CELL

Cancer Stem Cells: Impact, Heterogeneity, and Uncertainty

(2012) Jeffrey A. Magee et al.   CANCER CELL

CCL2 Mediates Cross-talk between Cancer Cells and Stromal Fibroblasts That Regulates Breast Cancer Stem Cells

(2012) A. Tsuyada et al.   CANCER RESEARCH

STAT3 signaling pathway is necessary for cell survival and tumorsphere forming capacity in ALDH+/CD133+ stem cell-like human colon cancer cells

(2011) Li Lin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Paracrine and Autocrine Signals Induce and Maintain Mesenchymal and Stem Cell States in the Breast

(2011) Christina Scheel et al.   CELL

CD24+ Liver Tumor-Initiating Cells Drive Self-Renewal and Tumor Initiation through STAT3-Mediated NANOG Regulation

(2011) Terence Kin Wah Lee et al.   Cell Stem Cell

c-Met represents a potential therapeutic target for personalized treatment in hepatocellular carcinoma

(2011) Hanning You et al.   HEPATOLOGY

Breast cancer stem cells, cytokine networks, and the tumor microenvironment

(2011) Hasan Korkaya et al.   JOURNAL OF CLINICAL INVESTIGATION

Microenvironmental regulation of stem cells in intestinal homeostasis and cancer

(2011) Jan Paul Medema et al.   NATURE

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

(2010) Louis Vermeulen et al.   NATURE CELL BIOLOGY

MET signalling: principles and functions in development, organ regeneration and cancer

(2010) Livio Trusolino et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

CD24 Is a Novel Predictor for Poor Prognosis of Hepatocellular Carcinoma after Surgery

(2009) X.-R. Yang et al.   CLINICAL CANCER RESEARCH

Cancer associated fibroblasts (CAFs) in tumor microenvironment

(2009) Fei Xing   Frontiers in Bioscience-Landmark

Cancer stem cells: mirage or reality?

(2009) Piyush B Gupta et al.   NATURE MEDICINE

STAT3 Is Required for Proliferation and Maintenance of Multipotency in Glioblastoma Stem Cells

(2009) Maureen M. Sherry et al.   STEM CELLS