Development of small molecule inhibitors targeting PBX1 transcription signaling as a novel cancer therapeutic strategy

A hydrophobic residue in the TALE homeodomain of PBX1 promotes epithelial-to-mesenchymal transition of gastric carcinoma

(2017) Changyu He et al.   Oncotarget

The Dualistic Model of Ovarian Carcinogenesis

(2016) Robert J. Kurman et al.   AMERICAN JOURNAL OF PATHOLOGY

Ovarian Cancer Chemoresistance Relies on the Stem Cell Reprogramming Factor PBX1

(2016) Jin-Gyoung Jung et al.   CANCER RESEARCH

CD44 and CD24 coordinate the reprogramming of nasopharyngeal carcinoma cells towards a cancer stem cell phenotype through STAT3 activation

(2016) Yao-An Shen et al.   Oncotarget

ZINC 15 – Ligand Discovery for Everyone

(2015) Teague Sterling et al.   Journal of Chemical Information and Modeling

The pioneer factor PBX1 is a novel driver of metastatic progression in ERα-positive breast cancer

(2015) Luca Magnani et al.   Oncotarget

Jagged1 expression regulated by Notch3 and Wnt/β-catenin signaling pathways in ovarian cancer

(2015)   Oncotarget

The cellular thermal shift assay for evaluating drug target interactions in cells

(2014) Rozbeh Jafari et al.   Nature Protocols

Transcription factor PREP1 induces EMT and metastasis by controlling the TGF- -SMAD3 pathway in non-small cell lung adenocarcinoma

(2014) M. Risolino et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide reprogramming of the chromatin landscape underlies endocrine therapy resistance in breast cancer

(2013) L. Magnani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Monitoring Drug Target Engagement in Cells and Tissues Using the Cellular Thermal Shift Assay

(2013) D. M. Molina et al.   SCIENCE

Defining NOTCH3 Target Genes in Ovarian Cancer

(2012) X. Chen et al.   CANCER RESEARCH

Implementing an online tool for genome-wide validation of survival-associated biomarkers in ovarian-cancer using microarray data from 1287 patients

(2012) Balázs Győrffy et al.   ENDOCRINE-RELATED CANCER

FRED and HYBRID docking performance on standardized datasets

(2012) Mark McGann   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Identification of PBX1 Target Genes in Cancer Cells by Global Mapping of PBX1 Binding Sites

(2012) Michelle M. Thiaville et al.   PLoS One

Integrated genomic analyses of ovarian carcinoma

(2011) D. Bell et al.   NATURE

Notch3 Overexpression Is Related to the Recurrence of Ovarian Cancer and Confers Resistance to Carboplatin

(2010) Joon Tae Park et al.   AMERICAN JOURNAL OF PATHOLOGY

Influence of Residual Tumor on Outcome in Ovarian Cancer Patients With FIGO Stage IV Disease

(2010) Pauline Wimberger et al.   ANNALS OF SURGICAL ONCOLOGY

Conformer Generation with OMEGA: Algorithm and Validation Using High Quality Structures from the Protein Databank and Cambridge Structural Database

(2010) Paul C. D. Hawkins et al.   Journal of Chemical Information and Modeling

Identifying significant genetic regulatory networks in the prostate cancer from microarray data based on transcription factor analysis and conditional independency

(2009) Hsiang-Yuan Yeh et al.   BMC Medical Genomics

Ovarian Cancer

(2008) Kathleen R. Cho et al.   Annual Review of Pathology-Mechanisms of Disease

Identification ofPbx1, a Potential Oncogene, as a Notch3 Target Gene in Ovarian Cancer

(2008) Joon T. Park et al.   CANCER RESEARCH

Pbx1 Regulates Self-Renewal of Long-Term Hematopoietic Stem Cells by Maintaining Their Quiescence

(2008) Francesca Ficara et al.   Cell Stem Cell