Roles of microRNAs and RNA-Binding Proteins in the Regulation of Colorectal Cancer Stem Cells
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Roles of microRNAs and RNA-Binding Proteins in the Regulation of Colorectal Cancer Stem Cells
Authors
Keywords
-
Journal
Cancers
Volume 9, Issue 12, Pages 143
Publisher
MDPI AG
Online
2017-10-24
DOI
10.3390/cancers9100143
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- A distinct role for Lgr5+ stem cells in primary and metastatic colon cancer
- (2017) Felipe de Sousa e Melo et al. NATURE
- Visualization and targeting of LGR5+ human colon cancer stem cells
- (2017) Mariko Shimokawa et al. NATURE
- Quaking Is a Key Regulator of Endothelial Cell Differentiation, Neovascularization, and Angiogenesis
- (2017) Amy Cochrane et al. STEM CELLS
- MiR-203 Interplays with Polycomb Repressive Complexes to Regulate the Proliferation of Neural Stem/Progenitor Cells
- (2017) Pei-Pei Liu et al. Stem Cell Reports
- Disturbance of the let-7/LIN28 double-negative feedback loop is associated with radio- and chemo-resistance in non-small cell lung cancer
- (2017) Jun Yin et al. PLoS One
- Quaking Regulates Neurofascin 155 Expression for Myelin and Axoglial Junction Maintenance
- (2016) L. Darbelli et al. JOURNAL OF NEUROSCIENCE
- miR-137 Regulates the Tumorigenicity of Colon Cancer Stem Cells through the Inhibition of DCLK1
- (2016) M. Sakaguchi et al. MOLECULAR CANCER RESEARCH
- A large-scale analysis of alternative splicing reveals a key role of QKI in lung cancer
- (2016) Fernando J. de Miguel et al. Molecular Oncology
- LIN28 phosphorylation by MAPK/ERK couples signalling to the post-transcriptional control of pluripotency
- (2016) Kaloyan M. Tsanov et al. NATURE CELL BIOLOGY
- Qki deficiency maintains stemness of glioma stem cells in suboptimal environment by downregulating endolysosomal degradation
- (2016) Takashi Shingu et al. NATURE GENETICS
- MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism
- (2016) Pratiti Bandopadhayay et al. NATURE GENETICS
- REST represses miR-124 and miR-203 to regulate distinct oncogenic properties of glioblastoma stem cells
- (2016) Anantha L. Marisetty et al. NEURO-ONCOLOGY
- Identification of small molecule inhibitors of the Lin28-mediated blockage of pre-let-7g processing
- (2016) Helen L. Lightfoot et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Quaking promotes monocyte differentiation into pro-atherogenic macrophages by controlling pre-mRNA splicing and gene expression
- (2016) Ruben G. de Bruin et al. Nature Communications
- Emerging functions of the Quaking RNA-binding proteins and link to human diseases
- (2016) Lama Darbelli et al. Wiley Interdisciplinary Reviews-RNA
- Global cancer statistics, 2012
- (2015) Lindsey A. Torre et al. CA-A CANCER JOURNAL FOR CLINICIANS
- IKK Enforces a LIN28B/TCF7L2 Positive Feedback Loop That Promotes Cancer Cell Stemness and Metastasis
- (2015) C. Chen et al. CANCER RESEARCH
- The RNA Binding Protein Quaking Regulates Formation of circRNAs
- (2015) Simon J. Conn et al. CELL
- Antisense inhibition of microRNA-21 and microRNA-221 in tumor-initiating stem-like cells modulates tumorigenesis, metastasis, and chemotherapy resistance in pancreatic cancer
- (2015) Yue Zhao et al. Targeted Oncology
- MicroRNA–mRNA interactions underlying colorectal cancer molecular subtypes
- (2015) Laura Cantini et al. Nature Communications
- Transformation of the intestinal epithelium by the MSI2 RNA-binding protein
- (2015) Shan Wang et al. Nature Communications
- miR-221/222 induces pancreatic cancer progression through the regulation of matrix metalloproteinases
- (2015) Qinhong Xu et al. Oncotarget
- The microRNA-200 family: small molecules with novel roles in cancer development, progression and therapy
- (2015) Brock Humphries et al. Oncotarget
- Tumor suppressive microRNA-137 negatively regulates Musashi-1 and colorectal cancer progression
- (2015) Amber R. Smith et al. Oncotarget
- The Msi Family of RNA-Binding Proteins Function Redundantly as Intestinal Oncoproteins
- (2015) Ning Li et al. Cell Reports
- MicroRNA Regulation of Human Breast Cancer Stem Cells
- (2015) Yohei Shimono et al. Journal of Clinical Medicine
- QKI impairs self-renewal and tumorigenicity of oral cancer cells via repression of SOX2
- (2014) Wei Lu et al. CANCER BIOLOGY & THERAPY
- CD44v6 Is a Marker of Constitutive and Reprogrammed Cancer Stem Cells Driving Colon Cancer Metastasis
- (2014) Matilde Todaro et al. Cell Stem Cell
- Colorectal Cancer Stem Cells: From the Crypt to the Clinic
- (2014) Ann Zeuner et al. Cell Stem Cell
- A microRNA 221– and 222–Mediated Feedback Loop Maintains Constitutive Activation of NFκB and STAT3 in Colorectal Cancer Cells
- (2014) Sanhong Liu et al. GASTROENTEROLOGY
- A census of human RNA-binding proteins
- (2014) Stefanie Gerstberger et al. NATURE REVIEWS GENETICS
- Receptor-type protein tyrosine phosphatase κ directly dephosphorylates CD133 and regulates downstream AKT activation
- (2014) O Shimozato et al. ONCOGENE
- The RNA-Binding Protein QKI Suppresses Cancer-Associated Aberrant Splicing
- (2014) Feng-Yang Zong et al. PLoS Genetics
- miR-142 regulates the tumorigenicity of human breast cancer stem cells through the canonical WNT signaling pathway
- (2014) Taichi Isobe et al. eLife
- A microRNA miR-34a-Regulated Bimodal Switch Targets Notch in Colon Cancer Stem Cells
- (2013) Pengcheng Bu et al. Cell Stem Cell
- Signaling between Transforming Growth Factor β (TGF-β) and Transcription Factor SNAI2 Represses Expression of MicroRNA miR-203 to Promote Epithelial-Mesenchymal Transition and Tumor Metastasis
- (2013) Xiangming Ding et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Wnt- -catenin pathway represses let-7 microRNA expression through transactivation of Lin28 to augment breast cancer stem cell expansion
- (2013) W.-Y. Cai et al. JOURNAL OF CELL SCIENCE
- Increased Expression of MicroRNA-221 in Gastric Cancer and Its Clinical Significance
- (2013) K Liu et al. JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
- The QKI-5 and QKI-6 RNA Binding Proteins Regulate the Expression of MicroRNA 7 in Glial Cells
- (2013) Yunling Wang et al. MOLECULAR AND CELLULAR BIOLOGY
- First microRNA mimic enters clinic
- (2013) Aaron Bouchie NATURE BIOTECHNOLOGY
- Adult intestinal stem cells: critical drivers of epithelial homeostasis and regeneration
- (2013) Nick Barker NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Redox regulation in stem-like cancer cells by CD44 variant isoforms
- (2013) O Nagano et al. ONCOGENE
- Involvement of miRNAs in the Differentiation of Human Glioblastoma Multiforme Stem-Like Cells
- (2013) Beatriz Aldaz et al. PLoS One
- Quaking and PTB control overlapping splicing regulatory networks during muscle cell differentiation
- (2013) M. P. Hall et al. RNA
- MicroRNA-137 represses Klf4 and Tbx3 during differentiation of mouse embryonic stem cells
- (2013) Ke Jiang et al. Stem Cell Research
- Fetal Deficiency of Lin28 Programs Life-Long Aberrations in Growth and Glucose Metabolism
- (2013) Gen Shinoda et al. STEM CELLS
- miR-203 Inhibits the Proliferation and Self-Renewal of Esophageal Cancer Stem-Like Cells by Suppressing Stem Renewal Factor Bmi-1
- (2013) Xiying Yu et al. STEM CELLS AND DEVELOPMENT
- Downregulation of tumor suppressor QKI in gastric cancer and its implication in cancer prognosis
- (2012) Yongqian Bian et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- High expression of Lin28 is associated with tumour aggressiveness and poor prognosis of patients in oesophagus cancer
- (2012) R Hamano et al. BRITISH JOURNAL OF CANCER
- CD66c is a novel marker for colorectal cancer stem cell isolation, and its silencing halts tumor growth in vivo
- (2012) Marica Gemei et al. CANCER
- Cancer Genetics and Epigenetics: Two Sides of the Same Coin?
- (2012) Jueng Soo You et al. CANCER CELL
- Induction of the RNA Regulator LIN28A Is Required for the Growth and Pathogenesis of RESTless Breast Tumors
- (2012) K. T. W. Gunsalus et al. CANCER RESEARCH
- Glycine Decarboxylase Activity Drives Non-Small Cell Lung Cancer Tumor-Initiating Cells and Tumorigenesis
- (2012) Wen Cai Zhang et al. CELL
- MicroRNA-137, an HMGA1 Target, Suppresses Colorectal Cancer Cell Invasion and Metastasis in Mice by Directly Targeting FMNL2
- (2012) Li Liang et al. GASTROENTEROLOGY
- STAR RNA-binding protein Quaking suppresses cancer via stabilization of specific miRNA
- (2012) A.-J. Chen et al. GENES & DEVELOPMENT
- miR-574-5p negatively regulatesQki6/7to impactβ-catenin/Wnt signalling and the development of colorectal cancer
- (2012) Shunlong Ji et al. GUT
- The miR-200 and miR-221/222 microRNA Families: Opposing Effects on Epithelial Identity
- (2012) Erin N. Howe et al. JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA
- Dclk1 distinguishes between tumor and normal stem cells in the intestine
- (2012) Yuki Nakanishi et al. NATURE GENETICS
- Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5+ stem cell
- (2012) Shiro Yui et al. NATURE MEDICINE
- Determinants of mRNA recognition and translation regulation by Lin28
- (2012) Xin-Xiang Lei et al. NUCLEIC ACIDS RESEARCH
- A Novel Network Integrating a miRNA-203/SNAI1 Feedback Loop which Regulates Epithelial to Mesenchymal Transition
- (2012) Michèle Moes et al. PLoS One
- Monoclonal Antibodies Against Lgr5 Identify Human Colorectal Cancer Stem Cells
- (2012) Kristel Kemper et al. STEM CELLS
- Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell
- (2012) Toshifumi Yae et al. Nature Communications
- Regulation of CD133 by HDAC6 Promotes β-Catenin Signaling to Suppress Cancer Cell Differentiation
- (2012) Anthony B. Mak et al. Cell Reports
- miR-34 – a microRNA replacement therapy is headed to the clinic
- (2012) Andreas G. Bader Frontiers in Genetics
- MicroRNA-221 inhibits CDKN1C/p57 expression in human colorectal carcinoma
- (2011) Kai Sun et al. ACTA PHARMACOLOGICA SINICA
- Msi-1 is a Predictor of Survival and a Novel Therapeutic Target in Colon Cancer
- (2011) Dawei Li et al. ANNALS OF SURGICAL ONCOLOGY
- CD44 Variant Regulates Redox Status in Cancer Cells by Stabilizing the xCT Subunit of System xc− and Thereby Promotes Tumor Growth
- (2011) Takatsugu Ishimoto et al. CANCER CELL
- LIN28B Promotes Colon Cancer Progression and Metastasis
- (2011) C. E. King et al. CANCER RESEARCH
- MiR-203 controls proliferation, migration and invasive potential of prostate cancer cell lines
- (2011) Giuditta Viticchiè et al. CELL CYCLE
- miR221/222 in Cancer: Their Role in Tumor Progression and Response to Therapy
- (2011) M. Garofalo et al. CURRENT MOLECULAR MEDICINE
- miR-137 Is Frequently Down-Regulated in Gastric Cancer and Is a Negative Regulator of Cdc42
- (2011) Qingjiang Chen et al. DIGESTIVE DISEASES AND SCIENCES
- Novel Double-negative Feedback Loop between Adenomatous Polyposis Coli and Musashi1 in Colon Epithelia
- (2011) Erick Spears et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- QKI-Mediated Alternative Splicing of the Histone Variant MacroH2A1 Regulates Cancer Cell Proliferation
- (2011) L. Novikov et al. MOLECULAR AND CELLULAR BIOLOGY
- Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling
- (2011) Wim de Lau et al. NATURE
- Single-cell dissection of transcriptional heterogeneity in human colon tumors
- (2011) Piero Dalerba et al. NATURE BIOTECHNOLOGY
- The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44
- (2011) Can Liu et al. NATURE MEDICINE
- Isolation and in vitro expansion of human colonic stem cells
- (2011) Peter Jung et al. NATURE MEDICINE
- miR-221/222 overexpession in human glioblastoma increases invasiveness by targeting the protein phosphate PTPμ
- (2011) C Quintavalle et al. ONCOGENE
- MiR-34a Targeting of Notch Ligand Delta-Like 1 Impairs CD15+/CD133+ Tumor-Propagating Cells and Supports Neural Differentiation in Medulloblastoma
- (2011) Pasqualino de Antonellis et al. PLoS One
- Genome-Wide Studies Reveal That Lin28 Enhances the Translation of Genes Important for Growth and Survival of Human Embryonic Stem Cells
- (2011) Shuping Peng et al. STEM CELLS
- Tumour-initiating stem-like cells in human prostate cancer exhibit increased NF-κB signalling
- (2011) Vinagolu K. Rajasekhar et al. Nature Communications
- The AC133 Epitope, but not the CD133 Protein, Is Lost upon Cancer Stem Cell Differentiation
- (2010) K. Kemper et al. CANCER RESEARCH
- Double-Negative Feedback Loop between Reprogramming Factor LIN28 and microRNA let-7 Regulates Aldehyde Dehydrogenase 1-Positive Cancer Stem Cells
- (2010) X. Yang et al. CANCER RESEARCH
- Epigenetic Silencing of miR-137 Is an Early Event in Colorectal Carcinogenesis
- (2010) F. Balaguer et al. CANCER RESEARCH
- Lin28: A MicroRNA Regulator with a Macro Role
- (2010) Srinivas R. Viswanathan et al. CELL
- Interplay between microRNAs and RNA-binding proteins determines developmental processes
- (2010) Martijn Kedde et al. CELL CYCLE
- Expression of the putative stem cell marker Musashi-1 in Barrett's esophagus and esophageal adenocarcinoma
- (2010) Y. V. Bobryshev et al. DISEASES OF THE ESOPHAGUS
- The ZEB/miR-200 feedback loop—a motor of cellular plasticity in development and cancer?
- (2010) Simone Brabletz et al. EMBO REPORTS
- miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic stem cells
- (2010) Carolina Tarantino et al. FASEB JOURNAL
- Characterization of the Intestinal Cancer Stem Cell Marker CD166 in the Human and Mouse Gastrointestinal Tract
- (2010) Trevor G. Levin et al. GASTROENTEROLOGY
- miR-137 targets Cdc42 expression, induces cell cycle G1 arrest and inhibits invasion in colorectal cancer cells
- (2010) Ming Liu et al. INTERNATIONAL JOURNAL OF CANCER
- The RNA binding protein Musashi1 regulates apoptosis, gene expression and stress granule formation in urothelial carcinoma cells
- (2010) Parvaneh Nikpour et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Progenitor stem cell marker expression by pulmonary carcinomas
- (2010) Andre L Moreira et al. MODERN PATHOLOGY
- Musashi1 regulates breast tumor cell proliferation and is a prognostic indicator of poor survival
- (2010) Xiao-Yang Wang et al. Molecular Cancer
- Regulation of myeloid leukaemia by the cell-fate determinant Musashi
- (2010) Takahiro Ito et al. NATURE
- Expansion of the eukaryotic proteome by alternative splicing
- (2010) Timothy W. Nilsen et al. NATURE
- Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia
- (2010) Michael G Kharas et al. NATURE MEDICINE
- Pluripotency factors Lin28 and Oct4 identify a sub-population of stem cell-like cells in ovarian cancer
- (2010) S Peng et al. ONCOGENE
- miR-221&222 Regulate TRAIL Resistance and Enhance Tumorigenicity through PTEN and TIMP3 Downregulation
- (2009) Michela Garofalo et al. CANCER CELL
- Aldehyde Dehydrogenase 1 Is a Marker for Normal and Malignant Human Colonic Stem Cells (SC) and Tracks SC Overpopulation during Colon Tumorigenesis
- (2009) E. H. Huang et al. CANCER RESEARCH
- MicroRNA-34a Inhibits Glioblastoma Growth by Targeting Multiple Oncogenes
- (2009) Y. Li et al. CANCER RESEARCH
- An Epigenetic Switch Involving NF-κB, Lin28, Let-7 MicroRNA, and IL6 Links Inflammation to Cell Transformation
- (2009) Dimitrios Iliopoulos et al. CELL
- MicroRNAs: Target Recognition and Regulatory Functions
- (2009) David P. Bartel CELL
- Downregulation of miRNA-200c Links Breast Cancer Stem Cells with Normal Stem Cells
- (2009) Yohei Shimono et al. CELL
- The miR-34 family in cancer and apoptosis
- (2009) H Hermeking CELL DEATH AND DIFFERENTIATION
- MicroRNA-221 Targets Bmf in Hepatocellular Carcinoma and Correlates with Tumor Multifocality
- (2009) L. Gramantieri et al. CLINICAL CANCER RESEARCH
- RNA-Binding Protein Quaking, a Critical Regulator of Colon Epithelial Differentiation and a Suppressor of Colon Cancer
- (2009) Guodong Yang et al. GASTROENTEROLOGY
- Expression of putative stem cell genes Musashi-1 and β1-integrin in human colorectal adenomas and adenocarcinomas
- (2009) Li-Fang Fan et al. INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
- The cancer stem cell marker CD133 has high prognostic impact but unknown functional relevance for the metastasis of human colon cancer
- (2009) David Horst et al. JOURNAL OF PATHOLOGY
- Direct cell reprogramming is a stochastic process amenable to acceleration
- (2009) Jacob Hanna et al. NATURE
- The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs
- (2009) Ulrich Wellner et al. NATURE CELL BIOLOGY
- Lin28 promotes transformation and is associated with advanced human malignancies
- (2009) Srinivas R Viswanathan et al. NATURE GENETICS
- Lin28-mediated post-transcriptional regulation of Oct4 expression in human embryonic stem cells
- (2009) Caihong Qiu et al. NUCLEIC ACIDS RESEARCH
- Stem-cell-abundant proteins Nanog, Nucleostemin and Musashi1 are highly expressed in malignant cervical epithelial cells
- (2008) Feng Ye et al. BMC CANCER
- Musashi1 modulates cell proliferation genes in the medulloblastoma cell line Daoy
- (2008) Patricia C Sanchez-Diaz et al. BMC CANCER
- miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells
- (2008) Joachim Silber et al. BMC Medicine
- MicroRNA-137 Targets Microphthalmia-Associated Transcription Factor in Melanoma Cell Lines
- (2008) L. T. Bemis et al. CANCER RESEARCH
- miR-203 represses ‘stemness’ by repressing ΔNp63
- (2008) A M Lena et al. CELL DEATH AND DIFFERENTIATION
- Subcellular Localization of Activated Leukocyte Cell Adhesion Molecule Is a Molecular Predictor of Survival in Ovarian Carcinoma Patients
- (2008) D. Mezzanzanica et al. CLINICAL CANCER RESEARCH
- CD44 is of Functional Importance for Colorectal Cancer Stem Cells
- (2008) L. Du et al. CLINICAL CANCER RESEARCH
- RNA-binding proteins and post-transcriptional gene regulation
- (2008) Tina Glisovic et al. FEBS LETTERS
- MicroRNA-221/222 Confers Tamoxifen Resistance in Breast Cancer by Targeting p27Kip1
- (2008) Tyler E. Miller et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Is CD133 a marker of metastatic colon cancer stem cells?
- (2008) Mark A. LaBarge et al. JOURNAL OF CLINICAL INVESTIGATION
- CD133 expression is not restricted to stem cells, and both CD133+ and CD133– metastatic colon cancer cells initiate tumors
- (2008) Sergey V. Shmelkov et al. JOURNAL OF CLINICAL INVESTIGATION
- Increased expression of the adult stem cell marker Musashi-1 in endometriosis and endometrial carcinoma
- (2008) M Götte et al. JOURNAL OF PATHOLOGY
- Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation
- (2008) Liqin Zhu et al. NATURE
- Crypt stem cells as the cells-of-origin of intestinal cancer
- (2008) Nick Barker et al. NATURE
- A skin microRNA promotes differentiation by repressing ‘stemness’
- (2008) Rui Yi et al. NATURE
- MiR-221 controls CDKN1C/p57 and CDKN1B/p27 expression in human hepatocellular carcinoma
- (2008) F Fornari et al. ONCOGENE
- Selective Blockade of MicroRNA Processing by Lin28
- (2008) S. R. Viswanathan et al. SCIENCE
- RNA-binding proteins in human genetic disease
- (2008) Kiven E. Lukong et al. TRENDS IN GENETICS
- Expression of CD133-1 and CD133-2 in ovarian cancer
- (2007) G. FERRANDINA et al. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation