RNA modifications and cancer

Epitranscriptomic Signatures in lncRNAs and Their Possible Roles in Cancer

(2019) Sorina Dinescu et al.   Genes

The chemical diversity of RNA modifications

(2019) R. Jordan Ontiveros et al.   BIOCHEMICAL JOURNAL

RNA modifications regulating cell fate in cancer

(2019) Sylvain Delaunay et al.   NATURE CELL BIOLOGY

Sensitive and quantitative probing of pseudouridine modification in mRNA and long non-coding RNA

(2019) Wen Zhang et al.   RNA

Regulation of Gene Expression by N-methyladenosine in Cancer

(2019) Jun Liu et al.   TRENDS IN CELL BIOLOGY

Interplay Between N6-Methyladenosine (m6A) and Non-coding RNAs in Cell Development and Cancer

(2019) Francesco Fazi et al.   Frontiers in Cell and Developmental Biology

Reading, writing and erasing mRNA methylation

(2019) Sara Zaccara et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

m1A Regulated Genes Modulate PI3K/AKT/mTOR and ErbB Pathways in Gastrointestinal Cancer

(2019) Yueshui Zhao et al.   Translational Oncology

Identification of YTH Domain-Containing Proteins as the Readers for N1-Methyladenosine in RNA

(2018) Xiaoxia Dai et al.   ANALYTICAL CHEMISTRY

HBXIP-elevated methyltransferase METTL3 promotes the progression of breast cancer via inhibiting tumor suppressor let-7g

(2018) Xiaoli Cai et al.   CANCER LETTERS

The role of A-to-I RNA editing in cancer development

(2018) Xiaoyan Xu et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Role of N 6 -methyladenosine modification in cancer

(2018) Xiaolan Deng et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Nutritional Control of Stem Cell Division through S-Adenosylmethionine in Drosophila Intestine

(2018) Fumiaki Obata et al.   DEVELOPMENTAL CELL

RNA N6-methyladenosine methyltransferase-like 3 promotes liver cancer progression through YTHDF2-dependent posttranscriptional silencing of SOCS2

(2018) Mengnuo Chen et al.   HEPATOLOGY

Elongator promotes the migration and invasion of hepatocellular carcinoma cell by the phosphorylation of AKT

(2018) Yi Xu et al.   International Journal of Biological Sciences

The dysregulation of tRNAs and tRNA derivatives in cancer

(2018) Shi-qiong Huang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance

(2018) Simone Pellegrino et al.   JOURNAL OF MOLECULAR BIOLOGY

Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation

(2018) Huilin Huang et al.   NATURE CELL BIOLOGY

ADARs and editing: The role of A-to-I RNA modification in cancer progression

(2018) Kajsa Fritzell et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

N6-methyladenosine links RNA metabolism to cancer progression

(2018) Dongjun Dai et al.   Cell Death & Disease

Cytoplasmic functions of long noncoding RNAs

(2018) Ji Heon Noh et al.   Wiley Interdisciplinary Reviews-RNA

Reversible RNA Modification N 1 -methyladenosine (m 1 A) in mRNA and tRNA

(2018) Chi Zhang et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Codon-specific translation reprogramming promotes resistance to targeted therapy

(2018) Francesca Rapino et al.   NATURE

Premature polyadenylation of MAGI3 is associated with diminished N6-methyladenosine in its large internal exon

(2018) Thomas K. Ni et al.   Scientific Reports

RNA Therapeutics in Cardiovascular Precision Medicine

(2018) Ageliki Laina et al.   Frontiers in Physiology

RNA m6A modification and its function in diseases

(2018) Jiyu Tong et al.   Frontiers of Medicine

RNA Modifications: Reversal Mechanisms and Cancer

(2018) Roopa Thapar et al.   BIOCHEMISTRY

Human ALKBH3-induced m1A demethylation increases the CSF-1 mRNA stability in breast and ovarian cancer cells

(2018) Ho-Hyung Woo et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

ADAR3 expression is an independent prognostic factor in lower-grade diffuse gliomas and positively correlated with the editing level of GRIA2Q607R

(2018) Ying Zhang et al.   Cancer Cell International

Transfer RNA demethylase ALKBH3 promotes cancer progression via induction of tRNA-derived small RNAs

(2018) Zhuojia Chen et al.   NUCLEIC ACIDS RESEARCH

Roles of Elongator Dependent tRNA Modification Pathways in Neurodegeneration and Cancer

(2018) Harmen Hawer et al.   Genes

Cervical cancer prevention and treatment in Latin America

(2017) Melissa S. Lopez et al.   JOURNAL OF SURGICAL ONCOLOGY

The m1A landscape on cytosolic and mitochondrial mRNA at single-base resolution

(2017) Modi Safra et al.   NATURE

The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells

(2017) Ly P Vu et al.   NATURE MEDICINE

RNA modifications and structures cooperate to guide RNA–protein interactions

(2017) Cole J.T. Lewis et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

MODOMICS: a database of RNA modification pathways. 2017 update

(2017) Pietro Boccaletto et al.   NUCLEIC ACIDS RESEARCH

Evidence for rRNA 2′-O-methylation plasticity: Control of intrinsic translational capabilities of human ribosomes

(2017) Jenny Erales et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

tsRNA signatures in cancer

(2017) Veronica Balatti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA editing of AZIN1 induces the malignant progression of non-small-cell lung cancers

(2017) Xueda Hu et al.   TUMOR BIOLOGY

The Epitranscriptome of Noncoding RNAs in Cancer

(2017) Manel Esteller et al.   Cancer Discovery

m 6 A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells

(2017) Qi Cui et al.   Cell Reports

AlkB homolog 3-mediated tRNA demethylation promotes protein synthesis in cancer cells

(2017) Yuko Ueda et al.   Scientific Reports

Determination of DNA and RNA Methylation in Circulating Tumor Cells by Mass Spectrometry

(2016) Wei Huang et al.   ANALYTICAL CHEMISTRY

ALKBH8 promotes bladder cancer growth and progression through regulating the expression of survivin

(2016) Ikumi Ohshio et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

ALKBH1-Mediated tRNA Demethylation Regulates Translation

(2016) Fange Liu et al.   CELL

Modulated Expression of Specific tRNAs Drives Gene Expression and Cancer Progression

(2016) Hani Goodarzi et al.   CELL

ADAR-Mediated RNA Editing Predicts Progression and Prognosis of Gastric Cancer

(2016) Tim Hon Man Chan et al.   GASTROENTEROLOGY

ADAR2 functions as a tumor suppressor via editing IGFBP7 in esophageal squamous cell carcinoma

(2016) Yuan-Bin Chen et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Rhein Inhibits AlkB Repair Enzymes and Sensitizes Cells to Methylated DNA Damage

(2016) Qi Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer

(2016) Sylvain Delaunay et al.   JOURNAL OF EXPERIMENTAL MEDICINE

N 6 -Methyladenosine Modification in a Long Noncoding RNA Hairpin Predisposes Its Conformation to Protein Binding

(2016) Katherine I. Zhou et al.   JOURNAL OF MOLECULAR BIOLOGY

The m 6 A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells

(2016) Shuibin Lin et al.   MOLECULAR CELL

Stem cell function and stress response are controlled by protein synthesis

(2016) Sandra Blanco et al.   NATURE

The dynamic N1-methyladenosine methylome in eukaryotic messenger RNA

(2016) Dan Dominissini et al.   NATURE

Transcriptome-wide mapping reveals reversible and dynamic N1-methyladenosine methylome

(2016) Xiaoyu Li et al.   Nature Chemical Biology

Post-transcriptional gene regulation by mRNA modifications

(2016) Boxuan Simen Zhao et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Erratum: Gene amplification-associated overexpression of the RNA editing enzyme ADAR1 enhances human lung tumorigenesis

(2016) C Anadón et al.   ONCOGENE

Overexpression of Ribosomal RNA in the Development of Human Cervical Cancer Is Associated with rDNA Promoter Hypomethylation

(2016) Hong Zhou et al.   PLoS One

Methyltransferase-like protein 16 binds the 3′-terminal triple helix of MALAT1 long noncoding RNA

(2016) Jessica A. Brown et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dysregulation of a family of short noncoding RNAs, tsRNAs, in human cancer

(2016) Yuri Pekarsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m6A-demethylation of NANOG mRNA

(2016) Chuanzhao Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tuning the ribosome: The influence of rRNA modification on eukaryotic ribosome biogenesis and function

(2016) Katherine E. Sloan et al.   RNA Biology

The mRNA-edited form of GABRA3 suppresses GABRA3-mediated Akt activation and breast cancer metastasis

(2016) Kiranmai Gumireddy et al.   Nature Communications

Deficient methylation and formylation of mt-tRNAMet wobble cytosine in a patient carrying mutations in NSUN3

(2016) Lindsey Van Haute et al.   Nature Communications

‘Acute myeloid leukemia: a comprehensive review and 2016 update’

(2016) I De Kouchkovsky et al.   Blood Cancer Journal

Methylation of miRNA genes and oncogenesis

(2015) V. I. Loginov et al.   BIOCHEMISTRY-MOSCOW

Somatic cancer mutations in the DNMT2 tRNA methyltransferase alter its catalytic properties

(2015) Winfried Elhardt et al.   BIOCHIMIE

The Genomic Landscape and Clinical Relevance of A-to-I RNA Editing in Human Cancers

(2015) Leng Han et al.   CANCER CELL

Endogenous tRNA-Derived Fragments Suppress Breast Cancer Progression via YBX1 Displacement

(2015) Hani Goodarzi et al.   CELL

5′ UTR m6A Promotes Cap-Independent Translation

(2015) Kate D. Meyer et al.   CELL

Structure of the Elongator cofactor complex Kti11/Kti13 provides insight into the role of Kti13 in Elongator-dependent tRNA modification

(2015) Olga Kolaj-Robin et al.   FEBS Journal

Structure of human MDM2 complexed with RPL11 reveals the molecular basis of p53 activation

(2015) Jiangge Zheng et al.   GENES & DEVELOPMENT

Reduced adenosine-to-inosine miR-455-5p editing promotes melanoma growth and metastasis

(2015) Einav Shoshan et al.   NATURE CELL BIOLOGY

Molecular insights into HSD10 disease: impact of SDR5C1 mutations on the human mitochondrial RNase P complex

(2015) Elisa Vilardo et al.   NUCLEIC ACIDS RESEARCH

m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation

(2015) Shay Geula et al.   SCIENCE

Structure of the Kti11/Kti13 Heterodimer and Its Double Role in Modifications of tRNA and Eukaryotic Elongation Factor 2

(2015) Sebastian Glatt et al.   STRUCTURE

Partial Loss of Rpl11 in Adult Mice Recapitulates Diamond-Blackfan Anemia and Promotes Lymphomagenesis

(2015) Lucia Morgado-Palacin et al.   Cell Reports

Elevated RNA Editing Activity Is a Major Contributor to Transcriptomic Diversity in Tumors

(2015) Nurit Paz-Yaacov et al.   Cell Reports

Principles Governing A-to-I RNA Editing in the Breast Cancer Transcriptome

(2015) Debora Fumagalli et al.   Cell Reports

Oncometabolite D-2-Hydroxyglutarate Inhibits ALKBH DNA Repair Enzymes and Sensitizes IDH Mutant Cells to Alkylating Agents

(2015) Pu Wang et al.   Cell Reports

Modulation of microRNA editing, expression and processing by ADAR2 deaminase in glioblastoma

(2015) Sara Tomaselli et al.   GENOME BIOLOGY

Design and synthesis of prostate cancer antigen-1 (PCA-1/ALKBH3) inhibitors as anti-prostate cancer drugs

(2014) Syuhei Nakao et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase

(2014) Xiao-Li Ping et al.   CELL RESEARCH

m6A RNA Modification Controls Cell Fate Transition in Mammalian Embryonic Stem Cells

(2014) Pedro J. Batista et al.   Cell Stem Cell

RNA editing inRHOQpromotes invasion potential in colorectal cancer

(2014) Sae-Won Han et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Pseudouridine profiling reveals regulated mRNA pseudouridylation in yeast and human cells

(2014) Thomas M. Carlile et al.   NATURE

Molecular basis for the recognition of methylated adenines in RNA by the eukaryotic YTH domain

(2014) S. Luo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biosynthesis of Ribosomal RNA in Nucleoli Regulates Pluripotency and Differentiation Ability of Pluripotent Stem Cells

(2014) Kanako Watanabe-Susaki et al.   STEM CELLS

NSUN4 Is a Dual Function Mitochondrial Protein Required for Both Methylation of 12S rRNA and Coordination of Mitoribosomal Assembly

(2014) Metodi Dimitrov Metodiev et al.   PLoS Genetics

Cotranscriptional events in eukaryotic ribosome synthesis

(2014) Tomasz W. Turowski et al.   Wiley Interdisciplinary Reviews-RNA

p53 Acts as a Safeguard of Translational Control by Regulating Fibrillarin and rRNA Methylation in Cancer

(2013) Virginie Marcel et al.   CANCER CELL

Adenosine-to-Inosine RNA Editing Mediated by ADARs in Esophageal Squamous Cell Carcinoma

(2013) Y.-R. Qin et al.   CANCER RESEARCH

Zebrafish midbrain slow-amplifying progenitors exhibit high levels of transcripts for nucleotide and ribosome biogenesis

(2013) G. Recher et al.   DEVELOPMENT

A human tRNA methyltransferase 9-like protein prevents tumour growth by regulating LIN9 and HIF1-α

(2013) Ulrike Begley et al.   EMBO Molecular Medicine

A disrupted RNA editing balance mediated by ADARs (Adenosine DeAminases that act on RNA) in human hepatocellular carcinoma

(2013) Tim Hon Man Chan et al.   GUT

MicroRNA-mediated loss of ADAR1 in metastatic melanoma promotes tumor growth

(2013) Yael Nemlich et al.   JOURNAL OF CLINICAL INVESTIGATION

A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation

(2013) Jianzhao Liu et al.   Nature Chemical Biology

Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma

(2013) Leilei Chen et al.   NATURE MEDICINE

Ribosomal proteins L5 and L11 co-operatively inactivate c-Myc via RNA-induced silencing complex

(2013) J-M Liao et al.   ONCOGENE

Elevated snoRNA biogenesis is essential in breast cancer

(2013) H Su et al.   ONCOGENE

tRNA-derived microRNA modulates proliferation and the DNA damage response and is down-regulated in B cell lymphoma

(2013) Roy L. Maute et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNase P enzymes

(2013) Michael J. Howard et al.   RNA Biology

5S Ribosomal RNA Is an Essential Component of a Nascent Ribosomal Precursor Complex that Regulates the Hdm2-p53 Checkpoint

(2013) Giulio Donati et al.   Cell Reports

The Amidation Step of Diphthamide Biosynthesis in Yeast Requires DPH6, a Gene Identified through Mining the DPH1-DPH5 Interaction Network

(2013) Shanow Uthman et al.   PLoS Genetics

Mutations in NSUN2 Cause Autosomal- Recessive Intellectual Disability

(2012) Lia Abbasi-Moheb et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Small nucleolar RNA expression profiling identifies potential prognostic markers in peripheral T-cell lymphoma

(2012) W. Valleron et al.   BLOOD

PCA-1/ALKBH3 Contributes to Pancreatic Cancer by Supporting Apoptotic Resistance and Angiogenesis

(2012) I. Yamato et al.   CANCER RESEARCH

A Role for tRNA Modifications in Genome Structure and Codon Usage

(2012) Eva Maria Novoa et al.   CELL

c-Myc Is a Universal Amplifier of Expressed Genes in Lymphocytes and Embryonic Stem Cells

(2012) Zuqin Nie et al.   CELL

Transcriptional Amplification in Tumor Cells with Elevated c-Myc

(2012) Charles Y. Lin et al.   CELL

MYC on the Path to Cancer

(2012) Chi V. Dang   CELL

Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons

(2012) Kate D. Meyer et al.   CELL

ALKBH3 Contributes to Survival and Angiogenesis of Human Urothelial Carcinoma Cells through NADPH Oxidase and Tweak/Fn14/VEGF Signals

(2012) K. Shimada et al.   CLINICAL CANCER RESEARCH

Suprainduction of p53 by disruption of 40S and 60S ribosome biogenesis leads to the activation of a novel G2/M checkpoint

(2012) S. Fumagalli et al.   GENES & DEVELOPMENT

DERP6 (ELP5) and C3ORF75 (ELP6) Regulate Tumorigenicity and Migration of Melanoma Cells as Subunits of Elongator

(2012) Pierre Close et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Attenuated adenosine-to-inosine editing of microRNA-376a* promotes invasiveness of glioblastoma cells

(2012) Yukti Choudhury et al.   JOURNAL OF CLINICAL INVESTIGATION

Specific small nucleolar RNA expression profiles in acute leukemia

(2012) W Valleron et al.   LEUKEMIA

ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility

(2012) Guanqun Zheng et al.   MOLECULAR CELL

Widespread occurrence of 5-methylcytosine in human coding and non-coding RNA

(2012) Jeffrey E. Squires et al.   NUCLEIC ACIDS RESEARCH

ADAR2-editing activity inhibits glioblastoma growth through the modulation of the CDC14B/Skp2/p21/p27 axis

(2012) F Galeano et al.   ONCOGENE

Mutual protection of ribosomal proteins L5 and L11 from degradation is essential for p53 activation upon ribosomal biogenesis stress

(2012) S. Bursac et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conservation of the relative tRNA composition in healthy and cancerous tissues

(2012) S. Mahlab et al.   RNA

Trmt61B is a methyltransferase responsible for 1-methyladenosine at position 58 of human mitochondrial tRNAs

(2012) T. Chujo et al.   RNA

Reversible RNA adenosine methylation in biological regulation

(2012) Guifang Jia et al.   TRENDS IN GENETICS

The expression pattern of small nucleolar and small Cajal body-specific RNAs characterizes distinct molecular subtypes of multiple myeloma

(2012) D Ronchetti et al.   Blood Cancer Journal

Alterations in Nucleolar Structure and Gene Expression Programs in Prostatic Neoplasia Are Driven by the MYC Oncogene

(2011) Cheryl M. Koh et al.   AMERICAN JOURNAL OF PATHOLOGY

ALKBH3, a human AlkB homologue, contributes to cell survival in human non-small-cell lung cancer

(2011) M Tasaki et al.   BRITISH JOURNAL OF CANCER

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Transfer RNA Methytransferases and Their Corresponding Modifications in Budding Yeast and Humans: Activities, Predications, and Potential Roles in Human Health

(2011) William L. Towns et al.   DNA AND CELL BIOLOGY

Requirement of rRNA Methylation for 80S Ribosome Assembly on a Cohort of Cellular Internal Ribosome Entry Sites

(2011) A. Basu et al.   MOLECULAR AND CELLULAR BIOLOGY

Ribosomal Protein L11 Recruits miR-24/miRISC To Repress c-Myc Expression in Response to Ribosomal Stress

(2011) K. B. Challagundla et al.   MOLECULAR AND CELLULAR BIOLOGY

Angiogenin-Induced tRNA Fragments Inhibit Translation Initiation

(2011) Pavel Ivanov et al.   MOLECULAR CELL

rRNA Pseudouridylation Defects Affect Ribosomal Ligand Binding and Translational Fidelity from Yeast to Human Cells

(2011) Karen Jack et al.   MOLECULAR CELL

N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

(2011) Guifang Jia et al.   Nature Chemical Biology

Functions and Regulation of RNA Editing by ADAR Deaminases

(2010) Kazuko Nishikura   Annual Review of Biochemistry

Organelle-Like Membrane Compartmentalization of Positive-Strand RNA Virus Replication Factories

(2010) Johan A. den Boon et al.   Annual Review of Microbiology

An ARF-Independent c-MYC-Activated Tumor Suppression Pathway Mediated by Ribosomal Protein-Mdm2 Interaction

(2010) Everardo Macias et al.   CANCER CELL

Novel Dyskerin-Mediated Mechanism of p53 Inactivation through Defective mRNA Translation

(2010) Lorenzo Montanaro et al.   CANCER RESEARCH

Loss of Function of the Tumor Suppressor DKC1 Perturbs p27 Translation Control and Contributes to Pituitary Tumorigenesis

(2010) C. Bellodi et al.   CANCER RESEARCH

Deregulation of oncogene-induced senescence and p53 translational control in X-linked dyskeratosis congenita

(2010) Cristian Bellodi et al.   EMBO JOURNAL

RNA methylation by Dnmt2 protects transfer RNAs against stress-induced cleavage

(2010) M. Schaefer et al.   GENES & DEVELOPMENT

Ribosomal Protein L11 Associates with c-Myc at 5 S rRNA and tRNA Genes and Regulates Their Expression

(2010) Mu-Shui Dai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genomic gain of 5p15 leads to over-expression of Misu (NSUN2) in breast cancer

(2009) Michaela Frye et al.   CANCER LETTERS

A Novel Human AlkB Homologue, ALKBH8, Contributes to Human Bladder Cancer Progression

(2009) K. Shimada et al.   CANCER RESEARCH

A Genome-wide RNAi Screen Identifies Multiple Synthetic Lethal Interactions with the Ras Oncogene

(2009) Ji Luo et al.   CELL

A novel class of small RNAs: tRNA-derived RNA fragments (tRFs)

(2009) Yong Sun Lee et al.   GENES & DEVELOPMENT

The nucleolar RNA methyltransferase Misu (NSun2) is required for mitotic spindle stability

(2009) Shobbir Hussain et al.   JOURNAL OF CELL BIOLOGY

tRNA over-expression in breast cancer and functional consequences

(2009) Mariana Pavon-Eternod et al.   NUCLEIC ACIDS RESEARCH

Small-molecule inhibitors of the p53-HDM2 interaction for the treatment of cancer

(2008) Sharmila Patel et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Crystal Structure of Thermus thermophilus tRNA m1A58 Methyltransferase and Biophysical Characterization of Its Interaction with tRNA

(2008) Pierre Barraud et al.   JOURNAL OF MOLECULAR BIOLOGY

Yeast α-tubulin suppressor Ats1/Kti13 relates to the Elongator complex and interacts with Elongator partner protein Kti11

(2008) René Zabel et al.   MOLECULAR MICROBIOLOGY

An Oncogene-Induced DNA Damage Model for Cancer Development

(2008) T. D. Halazonetis et al.   SCIENCE