RUNX3 suppresses metastasis and stemness by inhibiting Hedgehog signaling in colorectal cancer
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Title
RUNX3 suppresses metastasis and stemness by inhibiting Hedgehog signaling in colorectal cancer
Authors
Keywords
-
Journal
CELL DEATH AND DIFFERENTIATION
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-07-05
DOI
10.1038/s41418-019-0379-5
References
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Related references
Note: Only part of the references are listed.- The Prognostic Significance of the Hedgehog Signaling Pathway in Colorectal Cancer
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- Cooperative integration between HEDGEHOG-GLI signalling and other oncogenic pathways: implications for cancer therapy
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- Role of RUNX3 in Suppressing Metastasis and Angiogenesis of Human Prostate Cancer
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- Hedgehog Pathway Signaling Regulates Human Colon Carcinoma HT-29 Epithelial Cell Line Apoptosis and Cytokine Secretion
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- Expression of RUNX3 in skin cancers
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- A Perspective on Cancer Cell Metastasis
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- Cancer Stem Cells and Self-renewal
- (2010) C. A. O'Brien et al. CLINICAL CANCER RESEARCH
- Targeting Notch to Target Cancer Stem Cells
- (2010) A. Pannuti et al. CLINICAL CANCER RESEARCH
- Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion
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- RUNX3 directly interacts with intracellular domain of Notch1 and suppresses Notch signaling in hepatocellular carcinoma cells
- (2009) Juan Gao et al. EXPERIMENTAL CELL RESEARCH
- Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia
- (2009) Chen Zhao et al. NATURE
- Runx2 Transcriptional Activation of Indian Hedgehog and a Downstream Bone Metastatic Pathway in Breast Cancer Cells
- (2008) J. Pratap et al. CANCER RESEARCH
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