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Title
Ion channels as therapeutic antibody targets
Authors
Keywords
-
Journal
mAbs
Volume -, Issue -, Pages 1-32
Publisher
Informa UK Limited
Online
2018-12-10
DOI
10.1080/19420862.2018.1548232
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- (2011) Dimitra Gkika et al. ASIAN JOURNAL OF ANDROLOGY
- Human ether-à-go-go gene potassium channels are regulated by EGFR tyrosine kinase
- (2011) Wei Wu et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Senicapoc trial results support the existence of different sub-phenotypes of sickle cell disease with possible drug-induced phenotypic shifts
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- Improvements in haemolysis and indicators of erythrocyte survival do not correlate with acute vaso-occlusive crises in patients with sickle cell disease: a phase III randomized, placebo-controlled, double-blind study of the gardos channel blocker senicapo
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- Targeted silencing of TRPM7 ion channel induces replicative senescence and produces enhanced cytotoxicity with gemcitabine in pancreatic adenocarcinoma
- (2011) Nelson S. Yee et al. CANCER LETTERS
- Thermo-sensitive transient receptor potential vanilloid channel-1 regulates intracellular calcium and triggers chromogranin A secretion in pancreatic neuroendocrine BON-1 tumor cells
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- The lymphocyte potassium channels Kv1.3 and KCa3.1 as targets for immunosuppression
- (2011) Jenny Lam et al. DRUG DEVELOPMENT RESEARCH
- Modulating antibody pharmacokinetics using hydrophilic polymers
- (2011) Chen Chen et al. Expert Opinion on Drug Delivery
- Genetic and Pharmacologic Inhibition of the Ca2+ Influx Channel TRPC3 Protects Secretory Epithelia From Ca2+-Dependent Toxicity
- (2011) Min Seuk Kim et al. GASTROENTEROLOGY
- Transgenic expression of bovine neonatal Fc receptor in mice boosts immune response and improves hybridoma production efficiency without any sign of autoimmunity
- (2011) Zita Schneider et al. IMMUNOLOGY LETTERS
- Glioma-specific Cation Conductance Regulates Migration and Cell Cycle Progression
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- Enhancement of antibody responses to native G protein-coupled receptors using E. coli GroEL as a molecular adjuvant in DNA immunization
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- Autoantibodies in Melanoma-Associated Retinopathy Target TRPM1 Cation Channels of Retinal ON Bipolar Cells
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- Expression of functional TRPA1 receptor on human lung fibroblast and epithelial cells
- (2011) Indranil Mukhopadhyay et al. JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION
- Non-cysteine linked MUC1 cytoplasmic dimers are required for Src recruitment and ICAM-1 binding induced cell invasion
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- Progressive encephalomyelitis with rigidity and myoclonus: Glycine and NMDA receptor antibodies
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- Proteinase-activated receptor 2 sensitizes transient receptor potential vanilloid 1, transient receptor potential vanilloid 4, and transient receptor potential ankyrin 1 in paclitaxel-induced neuropathic pain
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- Loss of breast epithelial marker hCLCA2 promotes epithelial-to-mesenchymal transition and indicates higher risk of metastasis
- (2011) V Walia et al. ONCOGENE
- P2X7 receptor activation enhances SK3 channels- and cystein cathepsin-dependent cancer cells invasiveness
- (2011) B Jelassi et al. ONCOGENE
- Transient receptor potential (TRP) channels as drug targets for diseases of the digestive system
- (2011) Peter Holzer PHARMACOLOGY & THERAPEUTICS
- Pharmacological Blockade of TRPM8 Ion Channels Alters Cold and Cold Pain Responses in Mice
- (2011) Wendy M. Knowlton et al. PLoS One
- Rapid Internalization of the Oncogenic K+ Channel KV10.1
- (2011) Tobias Kohl et al. PLoS One
- Calcium store sensor stromal-interaction molecule 1-dependent signaling plays an important role in cervical cancer growth, migration, and angiogenesis
- (2011) Y.-F. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Functional prokaryotic-eukaryotic chimera from the pentameric ligand-gated ion channel family
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- The birth and postnatal development of purinergic signalling
- (2010) G. Burnstock et al. Acta Physiologica
- Extracellular ATP Is a Danger Signal Activating P2X7Receptor in Lung Inflammation and Fibrosis
- (2010) Nicolas Riteau et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Ghrelin inhibits proliferation and increases T-type Ca2+ channel expression in PC-3 human prostate carcinoma cells
- (2010) Nundehui Díaz-Lezama et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Modulating the pharmacokinetics of therapeutic antibodies
- (2010) A. Constantinou et al. BIOTECHNOLOGY LETTERS
- Chemotherapy resistance in acute lymphoblastic leukemia requires hERG1 channels and is overcome by hERG1 blockers
- (2010) S. Pillozzi et al. BLOOD
- Differential effects of Kv11.1 activators on Kv11.1a, Kv11.1b and Kv11.1a/Kv11.1b channels
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- Expression and significance of HERG protein in gastric cancer
- (2010) Xiao-Dong Shao et al. CANCER BIOLOGY & THERAPY
- Potent suppression of vascular smooth muscle cell migration and human neointimal hyperplasia by KV1.3 channel blockers
- (2010) Alex Cheong et al. CARDIOVASCULAR RESEARCH
- Structural Insights into the Function of P2X4: An ATP-Gated Cation Channel of Neuroendocrine Cells
- (2010) Stanko S. Stojilkovic et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Studies of ion channels using expressed protein ligation
- (2010) Paul J Focke et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Contribution of voltage-gated potassium channels to the regulation of apoptosis
- (2010) Ildikò Szabò et al. FEBS LETTERS
- Screening technologies for ion channel drug discovery
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- Use of Venom Peptides to Probe Ion Channel Structure and Function
- (2010) Sébastien Dutertre et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Activation of Macrophages by P2X7-Induced Microvesicles from Myeloid Cells Is Mediated by Phospholipids and Is Partially Dependent on TLR4
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- The Beneficial Effect of Blocking Kv1.3 in the Psoriasiform SCID Mouse Model
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- Essential Role of TRPC6 Channels in G2/M Phase Transition and Development of Human Glioma
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- Ziconotide for treatment of severe chronic pain
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- Pharmacokinetics and lung distribution of a humanized anti-RAGE antibody in wild-type and RAGE-/-mice
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- Malignant transformation in a defined genetic background: proteome changes displayed by 2D-PAGE
- (2010) Stephanie M Pütz et al. Molecular Cancer
- Antibody recycling by engineered pH-dependent antigen binding improves the duration of antigen neutralization
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- International Union of Basic and Clinical Pharmacology. LXXVI. Current Progress in the Mammalian TRP Ion Channel Family
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- Podocyte-Specific Overexpression of Wild Type or Mutant Trpc6 in Mice Is Sufficient to Cause Glomerular Disease
- (2010) Paola Krall et al. PLoS One
- Inhibition of the K+ channel KCa3.1 ameliorates T cell-mediated colitis
- (2010) L. Di et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Orai1 contributes to the establishment of an apoptosis-resistant phenotype in prostate cancer cells
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- State-dependent block of HERG potassium channels by R-roscovitine: implications for cancer therapy
- (2009) Sindura B. Ganapathi et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Ca2+ influx via TRPC channels induces NF-κB-dependent A20 expression to prevent thrombin-induced apoptosis in endothelial cells
- (2009) Prabhakar B. Thippegowda et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Functional Role of Canonical Transient Receptor Potential 1 and Canonical Transient Receptor Potential 3 in Normal and Asthmatic Airway Smooth Muscle Cells
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- TRPM8 and prostate cancer: to overexpress or repress, that is the question—comment on “Effects of TRPM8 on proliferation and motility of prostate cancer PC-3 cells” by Yang ZH et al. in Asian Journal of Andrology
- (2009) Prakash Kulkarni ASIAN JOURNAL OF ANDROLOGY
- Effects of TRPM8 on the proliferation and motility of prostate cancer PC-3 cells
- (2009) Zhong-Hua Yang et al. ASIAN JOURNAL OF ANDROLOGY
- hCLCA2 Is a p53-Inducible Inhibitor of Breast Cancer Cell Proliferation
- (2009) V. Walia et al. CANCER RESEARCH
- Polymorphisms in fatty acid metabolism-related genes are associated with colorectal cancer risk
- (2009) Birgit Hoeft et al. CARCINOGENESIS
- A Functional Single-Nucleotide Polymorphism in the TRPC6 Gene Promoter Associated With Idiopathic Pulmonary Arterial Hypertension
- (2009) Ying Yu et al. CIRCULATION
- Calcitriol inhibits Ether-à go-go potassium channel expression and cell proliferation in human breast cancer cells
- (2009) Rocío García-Becerra et al. EXPERIMENTAL CELL RESEARCH
- Targeting voltage-gated sodium channels for pain therapy
- (2009) Jeffrey J Clare EXPERT OPINION ON INVESTIGATIONAL DRUGS
- The functional network of ion channels in T lymphocytes
- (2009) Michael D. Cahalan et al. IMMUNOLOGICAL REVIEWS
- Blockade of TRPC6 channels induced G2/M phase arrest and suppressed growth in human gastric cancer cells
- (2009) Rong Cai et al. INTERNATIONAL JOURNAL OF CANCER
- The P2X7 Receptor Drives Microglial Activation and Proliferation: A Trophic Role for P2X7R Pore
- (2009) M. Monif et al. JOURNAL OF NEUROSCIENCE
- Membrane Proteins Solubilized Intact in Lipid Containing Nanoparticles Bounded by Styrene Maleic Acid Copolymer
- (2009) Timothy J. Knowles et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Crofelemer, an Antisecretory Antidiarrheal Proanthocyanidin Oligomer Extracted from Croton lechleri, Targets Two Distinct Intestinal Chloride Channels
- (2009) L. Tradtrantip et al. MOLECULAR PHARMACOLOGY
- Crystal structure of the ATP-gated P2X4 ion channel in the closed state
- (2009) Toshimitsu Kawate et al. NATURE
- Chloride channels as drug targets
- (2009) Alan S. Verkman et al. NATURE REVIEWS DRUG DISCOVERY
- Voltage-gated potassium channels as therapeutic targets
- (2009) Heike Wulff et al. NATURE REVIEWS DRUG DISCOVERY
- Renal fibrosis is attenuated by targeted disruption of KCa3.1 potassium channels
- (2009) I. Grgic et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Risk communication: the Avandia case, a pilot study
- (2009) Ragnar Lofstedt Expert Review of Clinical Pharmacology
- Efficacy and safety of the Gardos channel blocker, senicapoc (ICA-17043), in patients with sickle cell anemia
- (2008) K. I. Ataga et al. BLOOD
- Human embryonic stem cells and lung regeneration
- (2008) A Varanou et al. BRITISH JOURNAL OF PHARMACOLOGY
- Loss of classical transient receptor potential 6 channel reduces allergic airway response
- (2008) S. Sel et al. CLINICAL AND EXPERIMENTAL ALLERGY
- KCa3.1: target and marker for cancer, autoimmune disorder and vascular inflammation?
- (2008) Chuan-Chu Chou et al. EXPERT REVIEW OF MOLECULAR DIAGNOSTICS
- Imaging of Effector Memory T Cells during a Delayed-Type Hypersensitivity Reaction and Suppression by Kv1.3 Channel Block
- (2008) Melanie P. Matheu et al. IMMUNITY
- Eag1 and Bestrophin 1 Are Up-regulated in Fast-growing Colonic Cancer Cells
- (2008) Melanie Spitzner et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- CaV3.2 T-type Calcium Channels Are Involved in Calcium-dependent Secretion of Neuroendocrine Prostate Cancer Cells
- (2008) Florian Gackière et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The intermediate-conductance calcium-activated potassium channel KCa3.1 contributes to atherogenesis in mice and humans
- (2008) Kazuyoshi Toyama et al. JOURNAL OF CLINICAL INVESTIGATION
- Up-Regulation of P2X4 Receptors in Spinal Microglia after Peripheral Nerve Injury Mediates BDNF Release and Neuropathic Pain
- (2008) L. Ulmann et al. JOURNAL OF NEUROSCIENCE
- Transmural variation in myosin heavy chain isoform expression modulates the timing of myocardial force generation in porcine left ventricle
- (2008) Julian E. Stelzer et al. JOURNAL OF PHYSIOLOGY-LONDON
- A nomenclature for ligand-gated ion channels
- (2008) Graham L. Collingridge et al. NEUROPHARMACOLOGY
- Increased Level of Extracellular ATP at Tumor Sites: In Vivo Imaging with Plasma Membrane Luciferase
- (2008) Patrizia Pellegatti et al. PLoS One
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