Selection of an ASIC1a-blocking combinatorial antibody that protects cells from ischemic death

Human ASIC1a mediates stronger acid-induced responses as compared with mouse ASIC1a

(2018) Yuanyuan Xu et al.   FASEB JOURNAL

Molecular Basis for Allosteric Inhibition of Acid-Sensing Ion Channel 1a by Ibuprofen

(2017) Timothy Lynagh et al.   JOURNAL OF MEDICINAL CHEMISTRY

Potent neuroprotection after stroke afforded by a double-knot spider-venom peptide that inhibits acid-sensing ion channel 1a

(2017) Irène R. Chassagnon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Design and Characterization of a Human Monoclonal Antibody that Modulates Mutant Connexin 26 Hemichannels Implicated in Deafness and Skin Disorders

(2017) Liang Xu et al.   Frontiers in Molecular Neuroscience

Scipion: A software framework toward integration, reproducibility and validation in 3D electron microscopy

(2016) J.M. de la Rosa-Trevín et al.   JOURNAL OF STRUCTURAL BIOLOGY

ASIC1a regulates insular long-term depression and is required for the extinction of conditioned taste aversion

(2016) Wei-Guang Li et al.   Nature Communications

ASICs and neuropeptides

(2015) Jonathan S. Vick et al.   NEUROPHARMACOLOGY

Pharmacology of acid-sensing ion channels – Physiological and therapeutical perspectives

(2015) Anne Baron et al.   NEUROPHARMACOLOGY

Tissue acidosis induces neuronal necroptosis via ASIC1a channel independent of its ionic conduction

(2015) Yi-Zhi Wang et al.   eLife

Acid-sensing ion channels contribute to synaptic transmission and inhibit cocaine-evoked plasticity

(2014) Collin J Kreple et al.   NATURE NEUROSCIENCE

Screening and large-scale expression of membrane proteins in mammalian cells for structural studies

(2014) April Goehring et al.   Nature Protocols

SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information

(2014) Marco Biasini et al.   NUCLEIC ACIDS RESEARCH

Assembly of an Activated Rhodopsin–Transducin Complex in Nanoscale Lipid Bilayers

(2013) Aaron M. D’Antona et al.   BIOCHEMISTRY

GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkit

(2013) Sander Pronk et al.   BIOINFORMATICS

Xmipp 3.0: An improved software suite for image processing in electron microscopy

(2013) J.M. de la Rosa-Trevín et al.   JOURNAL OF STRUCTURAL BIOLOGY

Acid-sensing ion channels in pain and disease

(2013) John A. Wemmie et al.   NATURE REVIEWS NEUROSCIENCE

Application of asymmetric statistical potentials to antibody-protein docking

(2012) R. Brenke et al.   BIOINFORMATICS

N-Glycosylation of Acid-Sensing Ion Channel 1a Regulates Its Trafficking and Acidosis-Induced Spine Remodeling

(2012) L. Jing et al.   JOURNAL OF NEUROSCIENCE

Black mamba venom peptides target acid-sensing ion channels to abolish pain

(2012) Sylvie Diochot et al.   NATURE

Structure of the Acid-sensing ion channel 1 in complex with the gating modifier Psalmotoxin 1

(2012) Roger J.P. Dawson et al.   Nature Communications

Calcium-permeable ion channels involved in glutamate receptor-independent ischemic brain injury

(2011) Ming-hua Li et al.   ACTA PHARMACOLOGICA SINICA

Extracellular Spermine Exacerbates Ischemic Neuronal Injury through Sensitization of ASIC1a Channels to Extracellular Acidosis

(2011) B. Duan et al.   JOURNAL OF NEUROSCIENCE

Acidosis, Acid-Sensing Ion Channels, and Neuronal Cell Death

(2011) Yi-Zhi Wang et al.   MOLECULAR NEUROBIOLOGY

A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain

(2011) Christopher J. Bohlen et al.   NATURE

Identification of a Calcium Permeable Human Acid-sensing Ion Channel 1 Transcript Variant

(2010) Erin N. Hoagland et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Improved side-chain torsion potentials for the Amber ff99SB protein force field

(2010) Kresten Lindorff-Larsen et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS