Regulation of lymphocyte function by ORAI and STIM proteins in infection and autoimmunity

Permeation, selectivity and gating in store-operated CRAC channels

(2012) Beth A. McNally et al.   JOURNAL OF PHYSIOLOGY-LONDON

Immunodeficiency due to defects in store-operated calcium entry

(2011) Stefan Feske   Annals of the New York Academy of Sciences

ORAI-mediated calcium influx in T cell proliferation, apoptosis and tolerance

(2011) Bin Qu et al.   CELL CALCIUM

Calcium microdomains at the immunological synapse: how ORAI channels, mitochondria and calcium pumps generate local calcium signals for efficient T-cell activation

(2011) Ariel Quintana et al.   EMBO JOURNAL

The Calcium Sensors STIM1 and STIM2 Control B Cell Regulatory Function through Interleukin-10 Production

(2011) Masanori Matsumoto et al.   IMMUNITY

Antiviral and Regulatory T Cell Immunity in a Patient with Stromal Interaction Molecule 1 Deficiency

(2011) S. Fuchs et al.   JOURNAL OF IMMUNOLOGY

ORAI1 Deficiency Impairs Activated T Cell Death and Enhances T Cell Survival

(2011) K.-D. Kim et al.   JOURNAL OF IMMUNOLOGY

Differential STIM1 expression in T and B cell subsets suggests a role in determining antigen receptor signal amplitude

(2011) Yuval Yarkoni et al.   MOLECULAR IMMUNOLOGY

STIM1, PKC-δ and RasGRP set a threshold for proapoptotic Erk signaling during B cell development

(2011) Andre Limnander et al.   NATURE IMMUNOLOGY

ORAI1-mediated calcium influx is required for human cytotoxic lymphocyte degranulation and target cell lysis

(2011) A. Maul-Pavicic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Basis of Calcium Signaling in Lymphocytes: STIM and ORAI

(2010) Patrick G. Hogan et al.   Annual Review of Immunology

Immunodeficiency due to mutations in ORAI1 and STIM1

(2010) Stefan Feske et al.   CLINICAL IMMUNOLOGY

Induction of T cell anergy: integration of environmental cues and infectious tolerance

(2010) Pascal Chappert et al.   CURRENT OPINION IN IMMUNOLOGY

T-cell-specific deletion of STIM1 and STIM2 protects mice from EAE by impairing the effector functions of Th1 and Th17 cells

(2010) Jian Ma et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Whole-exome sequencing-based discovery of STIM1 deficiency in a child with fatal classic Kaposi sarcoma

(2010) Minji Byun et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Store-Operated Ca2+ Entry through ORAI1 Is Critical for T Cell-Mediated Autoimmunity and Allograft Rejection

(2010) C.-A. McCarl et al.   JOURNAL OF IMMUNOLOGY

Classic Kaposi Sarcoma in 3 Unrelated Turkish Children Born to Consanguineous Kindreds

(2010) G. Sahin et al.   PEDIATRICS

CRAC channelopathies

(2010) Stefan Feske   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Transcriptional regulatory networks in Th17 cell differentiation

(2009) Liang Zhou et al.   CURRENT OPINION IN IMMUNOLOGY

Kinetics of Early T Cell Receptor Signaling Regulate the Pathway of Lytic Granule Delivery to the Secretory Domain

(2009) Allison M. Beal et al.   IMMUNITY

Regulation of T-cell tolerance by calcium/NFAT signaling

(2009) Ian Baine et al.   IMMUNOLOGICAL REVIEWS

Calcium influx and signaling in cytotoxic T-lymphocyte lytic granule exocytosis

(2009) Arun T. Pores-Fernando et al.   IMMUNOLOGICAL REVIEWS

B-lymphocyte calcium inFlux

(2009) Leslie B. King et al.   IMMUNOLOGICAL REVIEWS

ORAI1 and STIM1 deficiency in human and mice: roles of store-operated Ca2+entry in the immune system and beyond

(2009) Stefan Feske   IMMUNOLOGICAL REVIEWS

ORAI1 deficiency and lack of store-operated Ca2+ entry cause immunodeficiency, myopathy, and ectodermal dysplasia

(2009) Christie-Ann McCarl et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

STIM1-Independent T Cell Development and Effector Function In Vivo

(2009) N. Beyersdorf et al.   JOURNAL OF IMMUNOLOGY

Stromal Interaction Molecules 1 and 2 Are Key Regulators of Autoreactive T Cell Activation in Murine Autoimmune Central Nervous System Inflammation

(2009) M. K. Schuhmann et al.   JOURNAL OF IMMUNOLOGY

Targeting Gut T Cell Ca2+ Release-Activated Ca2+ Channels Inhibits T Cell Cytokine Production and T-Box Transcription Factor T-Bet in Inflammatory Bowel Disease

(2009) A. Di Sabatino et al.   JOURNAL OF IMMUNOLOGY

STIMulating store-operated Ca2+ entry

(2009) Michael D. Cahalan   NATURE CELL BIOLOGY

The gene encoding early growth response 2, a target of the transcription factor NFAT, is required for the development and maturation of natural killer T cells

(2009) Vanja Lazarevic et al.   NATURE IMMUNOLOGY

Regulatory T cells exert checks and balances on self tolerance and autoimmunity

(2009) Kajsa Wing et al.   NATURE IMMUNOLOGY

STIM1Mutation Associated with a Syndrome of Immunodeficiency and Autoimmunity

(2009) Capucine Picard et al.   NEW ENGLAND JOURNAL OF MEDICINE

Stromal Interaction Molecule (STIM) 1 and STIM2 Calcium Sensing Regions Exhibit Distinct Unfolding and Oligomerization Kinetics

(2008) Peter B. Stathopulos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hair Loss and Defective T- and B-Cell Function in Mice Lacking ORAI1

(2008) Y. Gwack et al.   MOLECULAR AND CELLULAR BIOLOGY

Dynamic Movement of the Calcium Sensor STIM1 and the Calcium Channel Orai1 in Activated T-Cells: Puncta and Distal Caps

(2008) Valarie A. Barr et al.   MOLECULAR BIOLOGY OF THE CELL

Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance

(2008) Masatsugu Oh-hora et al.   NATURE IMMUNOLOGY

Orai1 and STIM1 move to the immunological synapse and are up-regulated during T cell activation

(2008) M. I. Lioudyno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA