Innate immune evasion strategies of SARS-CoV-2

Non-cell-autonomous disruption of nuclear architecture as a potential cause of COVID-19-induced anosmia

(2022) Marianna Zazhytska et al.   CELL

The T cell immune response against SARS-CoV-2

(2022) Paul Moss   NATURE IMMUNOLOGY

Pathological sequelae of long-haul COVID

(2022) Saurabh Mehandru et al.   NATURE IMMUNOLOGY

Innate immunity: the first line of defense against SARS-CoV-2

(2022) Michael S. Diamond et al.   NATURE IMMUNOLOGY

SARS-CoV-2 Spike Antagonizes Innate Antiviral Immunity by Targeting Interferon Regulatory Factor 3

(2022) Raul S. Freitas et al.   Frontiers in Cellular and Infection Microbiology

Molecular Mechanism of SARS-CoVs Orf6 Targeting the Rae1–Nup98 Complex to Compete With mRNA Nuclear Export

(2022) Tinghan Li et al.   Frontiers in Molecular Biosciences

Programmed cell death: the pathways to severe COVID-19?

(2022) Stefanie M. Bader et al.   BIOCHEMICAL JOURNAL

SARS-CoV-2 nsp5 Exhibits Stronger Catalytic Activity and Interferon Antagonism than Its SARS-CoV Ortholog

(2022) Jiyao Chen et al.   JOURNAL OF VIROLOGY

The life cycle and enigmatic egress of coronaviruses

(2022) Kristian Prydz et al.   MOLECULAR MICROBIOLOGY

SARS-CoV-2 is associated with changes in brain structure in UK Biobank

(2022) Gwenaëlle Douaud et al.   NATURE

The role of NSP6 in the biogenesis of the SARS-CoV-2 replication organelle

(2022) Simona Ricciardi et al.   NATURE

The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies

(2022) Jérémy Manry et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Viral Mimicry of Interleukin-17A by SARS-CoV-2 ORF8

(2022) Xin Wu et al.   mBio

SARS-CoV-2 NSP13 helicase suppresses interferon signaling by perturbing JAK1 phosphorylation of STAT1

(2022) Sin-Yee Fung et al.   Cell and Bioscience

Abnormal global alternative RNA splicing in COVID-19 patients

(2022) Changli Wang et al.   PLoS Genetics

SARS-CoV-2 Nsp14 mediates the effects of viral infection on the host cell transcriptome

(2022) Michela Zaffagni et al.   eLife

Pathology Assessments of Multiple Organs in Fatal COVID-19 in Intensive Care Unit vs. Non-intensive Care Unit Patients

(2022) Yoann Zerbib et al.   Frontiers in Medicine

Mild respiratory COVID can cause multi-lineage neural cell and myelin dysregulation

(2022) Anthony Fernández-Castañeda et al.   CELL

Immunological memory to SARS‐CoV ‐2 infection and COVID ‐19 vaccines

(2022) Alessandro Sette et al.   IMMUNOLOGICAL REVIEWS

Interferon resistance of emerging SARS-CoV-2 variants

(2022) Kejun Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Building the nuclear pore complex

(2022) Di Jiang   SCIENCE

Clues to long COVID

(2022) Jennifer Couzin-Frankel   SCIENCE

SARS-CoV-2 infection in hamsters and humans results in lasting and unique systemic perturbations post recovery

(2022) Justin J. Frere et al.   Science Translational Medicine

Nucleopore Traffic Is Hindered by SARS-CoV-2 ORF6 Protein to Efficiently Suppress IFN-β and IL-6 Secretion

(2022) Gianni Gori Savellini et al.   Viruses-Basel

Altered subgenomic RNA abundance provides unique insight into SARS-CoV-2 B.1.1.7/Alpha variant infections

(2022) Matthew D. Parker et al.   Communications Biology

Long Covid clues emerge from patients’ blood

(2022) Jennifer Couzin-Frankel   SCIENCE

Regulation of RIG-I-like receptor-mediated signaling: interaction between host and viral factors

(2021) Koji Onomoto et al.   Cellular & Molecular Immunology

Dynamic competition between SARS-CoV-2 NSP1 and mRNA on the human ribosome inhibits translation initiation

(2021) Christopher P. Lapointe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The SARS-CoV-2 nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein

(2021) Shan Lu et al.   Nature Communications

MDA5 Governs the Innate Immune Response to SARS-CoV-2 in Lung Epithelial Cells

(2021) Xin Yin et al.   Cell Reports

Pandemics Throughout History

(2021) Jocelyne Piret et al.   Frontiers in Microbiology

Effect of anakinra versus usual care in adults in hospital with COVID-19 and mild-to-moderate pneumonia (CORIMUNO-ANA-1): a randomised controlled trial

(2021) Serge Bureau et al.   Lancet Respiratory Medicine

SARS-CoV-2 nsp12 attenuates type I interferon production by inhibiting IRF3 nuclear translocation

(2021) Wenjing Wang et al.   Cellular & Molecular Immunology

The effect of tocilizumab on mortality in hospitalized patients with COVID-19: a meta-analysis of randomized controlled trials

(2021) Chia Siang Kow et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Leveraging the antiviral type I interferon system as a first line of defense against SARS-CoV-2 pathogenicity

(2021) Daisy A. Hoagland et al.   IMMUNITY

Genome-wide CRISPR screening identifies TMEM106B as a proviral host factor for SARS-CoV-2

(2021) Jim Baggen et al.   NATURE GENETICS

Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19

(2021)   NEW ENGLAND JOURNAL OF MEDICINE

Live and Wet Markets: Food Access versus the Risk of Disease Emergence

(2021) Mahmoud M. Naguib et al.   TRENDS IN MICROBIOLOGY

Sarbecovirus ORF6 proteins hamper the induction of interferon signaling

(2021) Izumi Kimura et al.   Cell Reports

Single cell resolution of SARS-CoV-2 tropism, antiviral responses, and susceptibility to therapies in primary human airway epithelium

(2021) Jessica K. Fiege et al.   PLoS Pathogens

Interleukin-6 Is a Biomarker for the Development of Fatal Severe Acute Respiratory Syndrome Coronavirus 2 Pneumonia

(2021) André Santa Cruz et al.   Frontiers in Immunology

Nsp1 protein of SARS-CoV-2 disrupts the mRNA export machinery to inhibit host gene expression

(2021) Ke Zhang et al.   Science Advances

SARS-CoV-2 Nucleocapsid Protein Targets RIG-I-Like Receptor Pathways to Inhibit the Induction of Interferon Response

(2021) Soo Jin Oh et al.   Cells

SARS-CoV-2, SARS-CoV-1, and HIV-1 derived ssRNA sequences activate the NLRP3 inflammasome in human macrophages through a non-classical pathway

(2021) Grant R. Campbell et al.   iScience

Type I and III interferon responses in SARS-CoV-2 infection

(2021) You-Me Kim et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Innate immune sensing of coronavirus and viral evasion strategies

(2021) Yusuke Kasuga et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

The role of IL-6 and IL-6 blockade in COVID-19

(2021) Nicola Potere et al.   Expert Review of Clinical Immunology

SARS‐CoV‐2 ORF9b antagonizes type I and III interferons by targeting multiple components of the RIG‐I/MDA‐5–MAVS, TLR3–TRIF, and cGAS–STING signaling pathways

(2021) Lulu Han et al.   JOURNAL OF MEDICAL VIROLOGY

SARS-CoV-2 non-structural protein 1 inhibits the interferon response by causing depletion of key host signaling factors.

(2021) Anil Kumar et al.   JOURNAL OF VIROLOGY

Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

(2021) Obbina Abani et al.   LANCET

SARS-CoV-2 uses a multipronged strategy to impede host protein synthesis

(2021) Yaara Finkel et al.   NATURE

2′-O methylation of RNA cap in SARS-CoV-2 captured by serial crystallography

(2021) Mateusz Wilamowski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

COVID-19-related anosmia is associated with viral persistence and inflammation in human olfactory epithelium and brain infection in hamsters

(2021) Guilherme Dias de Melo et al.   Science Translational Medicine

SARS-CoV-2 ORF6 Disrupts Bidirectional Nucleocytoplasmic Transport through Interactions with Rae1 and Nup98

(2021) Amin Addetia et al.   mBio

Crystal structure of SARS-CoV-2 Orf9b in complex with human TOM70 suggests unusual virus-host interactions

(2021) Xiaopan Gao et al.   Nature Communications

The SARS-CoV-2 nucleocapsid protein is dynamic, disordered, and phase separates with RNA

(2021) Jasmine Cubuk et al.   Nature Communications

Systematic functional analysis of SARS-CoV-2 proteins uncovers viral innate immune antagonists and remaining vulnerabilities

(2021) Manuel Hayn et al.   Cell Reports

SARS-CoV-2 Membrane Protein Inhibits Type I Interferon Production Through Ubiquitin-Mediated Degradation of TBK1

(2021) Liyan Sui et al.   Frontiers in Immunology

ISG15-dependent activation of the sensor MDA5 is antagonized by the SARS-CoV-2 papain-like protease to evade host innate immunity

(2021) GuanQun Liu et al.   Nature Microbiology

Dynamics of the SARS-CoV-2 nucleoprotein N-terminal domain triggers RNA duplex destabilization

(2021) Ícaro P. Caruso et al.   BIOPHYSICAL JOURNAL

The interferon landscape along the respiratory tract impacts the severity of COVID-19

(2021) Benedetta Sposito et al.   CELL

Coupling of N7-methyltransferase and 3′-5′ exoribonuclease with SARS-CoV-2 polymerase reveals mechanisms for capping and proofreading

(2021) Liming Yan et al.   CELL

The molecular mechanism of RIG‐I activation and signaling*

(2021) Daniel Thoresen et al.   IMMUNOLOGICAL REVIEWS

Phosphorylation of SARS-CoV-2 Orf9b Regulates Its Targeting to Two Binding Sites in TOM70 and Recruitment of Hsp90

(2021) Lukas Brandherm et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Effect of Canakinumab vs Placebo on Survival Without Invasive Mechanical Ventilation in Patients Hospitalized With Severe COVID-19

(2021) Roberto Caricchio et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Dynamic innate immune response determines susceptibility to SARS-CoV-2 infection and early replication kinetics

(2021) Nagarjuna R. Cheemarla et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The NF-κB transcriptional footprint is essential for SARS-CoV-2 replication

(2021) Benjamin E. Nilsson-Payant et al.   JOURNAL OF VIROLOGY

Pre-activated antiviral innate immunity in the upper airways controls early SARS-CoV-2 infection in children

(2021) J. Loske et al.   NATURE BIOTECHNOLOGY

Targeting liquid–liquid phase separation of SARS-CoV-2 nucleocapsid protein promotes innate antiviral immunity by elevating MAVS activity

(2021) Shuai Wang et al.   NATURE CELL BIOLOGY

SARS-CoV-2 takes its Toll

(2021) Alan Sariol et al.   NATURE IMMUNOLOGY

Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels: a double-blind, randomized controlled phase 3 trial

(2021) Evdoxia Kyriazopoulou et al.   NATURE MEDICINE

Tofacitinib in Patients Hospitalized with Covid-19 Pneumonia

(2021) Patrícia O. Guimarães et al.   NEW ENGLAND JOURNAL OF MEDICINE

Characterization of SARS2 Nsp15 nuclease activity reveals it's mad about U

(2021) Meredith N Frazier et al.   NUCLEIC ACIDS RESEARCH

SARS-CoV-2 viral proteins NSP1 and NSP13 inhibit interferon activation through distinct mechanisms

(2021) Christine Vazquez et al.   PLoS One

Translational shutdown and evasion of the innate immune response by SARS-CoV-2 NSP14 protein

(2021) Jack Chun-Chieh Hsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SARS-CoV-2 N Protein Targets TRIM25-Mediated RIG-I Activation to Suppress Innate Immunity

(2021) Gianni Gori Savellini et al.   Viruses-Basel

SARS-CoV-2 Nsp5 Demonstrates Two Distinct Mechanisms Targeting RIG-I and MAVS To Evade the Innate Immune Response

(2021) Yongzhen Liu et al.   mBio

SARS-CoV-2 suppresses IFNβ production mediated by NSP1, 5, 6, 15, ORF6 and ORF7b but does not suppress the effects of added interferon

(2021) Maya Shemesh et al.   PLoS Pathogens

Efficacy and safety of baricitinib for the treatment of hospitalised adults with COVID-19 (COV-BARRIER): a randomised, double-blind, parallel-group, placebo-controlled phase 3 trial

(2021) Vincent C Marconi et al.   Lancet Respiratory Medicine

RIG-I-Like Receptor-Mediated Recognition of Viral Genomic RNA of Severe Acute Respiratory Syndrome Coronavirus-2 and Viral Escape From the Host Innate Immune Responses

(2021) Takahisa Kouwaki et al.   Frontiers in Immunology

SARS-CoV-2–associated ssRNAs activate inflammation and immunity via TLR7/8

(2021) Valentina Salvi et al.   JCI Insight

TLR3 and TLR7 RNA Sensor Activation during SARS-COV-2 Infection

(2021) Daria Bortolotti et al.   Microorganisms

NSP9 of SARS-CoV-2 attenuates nuclear transport by hampering nucleoporin 62 dynamics and functions in host cells

(2021) Kei Makiyama et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SARS-CoV-2 3C-like protease antagonizes interferon-beta production by facilitating the degradation of IRF3

(2021) Wenwen Zhang et al.   CYTOKINE

Exploring the Catalytic Mechanism of the RNA Cap Modification by nsp16-nsp10 Complex of SARS-CoV-2 through a QM/MM Approach

(2021) José Rogério A. Silva et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

SARS-CoV-2 Spike Glycoprotein S1 Induces Neuroinflammation in BV-2 Microglia

(2021) Olumayokun A. Olajide et al.   MOLECULAR NEUROBIOLOGY

Evolution of enhanced innate immune evasion by SARS-CoV-2

(2021) Lucy G. Thorne et al.   NATURE

Mechanisms of SARS-CoV-2 entry into cells

(2021) Cody B. Jackson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The SARS-CoV-2 RNA polymerase is a viral RNA capping enzyme

(2021) Alexander P Walker et al.   NUCLEIC ACIDS RESEARCH

A prenylated dsRNA sensor protects against severe COVID-19

(2021) Arthur Wickenhagen et al.   SCIENCE

Current Understanding of the Innate Control of Toll-like Receptors in Response to SARS-CoV-2 Infection

(2021) Hi Eun Jung et al.   Viruses-Basel

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Membrane (M) and Spike (S) Proteins Antagonize Host Type I Interferon Response

(2021) Qi Zhang et al.   Frontiers in Cellular and Infection Microbiology

An interactive web-based dashboard to track COVID-19 in real time

(2020) Ensheng Dong et al.   LANCET INFECTIOUS DISEASES

A new coronavirus associated with human respiratory disease in China

(2020) Fan Wu et al.   NATURE

Clinical Characteristics of Coronavirus Disease 2019 in China

(2020) Wei-jie Guan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Toll-like Receptors and the Control of Immunity

(2020) Katherine A. Fitzgerald et al.   CELL

Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

(2020) Daniel Blanco-Melo et al.   CELL

Heightened Innate Immune Responses in the Respiratory Tract of COVID-19 Patients

(2020) Zhuo Zhou et al.   Cell Host & Microbe

COVID-19: consider cytokine storm syndromes and immunosuppression

(2020) Puja Mehta et al.   LANCET

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

(2020) David E. Gordon et al.   NATURE

Clinical Characteristics of Covid-19 in New York City

(2020) Parag Goyal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Coronavirus endoribonuclease targets viral polyuridine sequences to evade activating host sensors

(2020) Matthew Hackbart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SARS-CoV-2 (COVID-19) by the numbers

(2020) Yinon M Bar-On et al.   eLife

Molecular Basis for ADP-Ribose Binding to the Mac1 Domain of SARS-CoV-2 nsp3

(2020) David N. Frick et al.   BIOCHEMISTRY

SARS-CoV-2 Orf9b suppresses type I interferon responses by targeting TOM70

(2020) He-wei Jiang et al.   Cellular & Molecular Immunology

Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity

(2020) Donghyuk Shin et al.   NATURE

Extrapulmonary manifestations of COVID-19

(2020) Aakriti Gupta et al.   NATURE MEDICINE

Dexamethasone in Hospitalized Patients with Covid-19 — Preliminary Report

(2020)   NEW ENGLAND JOURNAL OF MEDICINE

Syrian hamsters as a small animal model for SARS-CoV-2 infection and countermeasure development

(2020) Masaki Imai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2

(2020) Matthias Thoms et al.   SCIENCE

A molecular pore spans the double membrane of the coronavirus replication organelle

(2020) Georg Wolff et al.   SCIENCE

Structural analysis of the SARS-CoV-2 methyltransferase complex involved in RNA cap creation bound to sinefungin

(2020) Petra Krafcikova et al.   Nature Communications

Crystal structures of SARS-CoV-2 ADP-ribose phosphatase: from the apo form to ligand complexes

(2020) Karolina Michalska et al.   IUCrJ

A dynamic nomenclature proposal for SARS-CoV-2 lineages to assist genomic epidemiology

(2020) Andrew Rambaut et al.   Nature Microbiology

Immunophenotyping of COVID-19 and influenza highlights the role of type I interferons in development of severe COVID-19

(2020) Jeong Seok Lee et al.   Science Immunology

SARS-CoV-2 Disrupts Splicing, Translation, and Protein Trafficking to Suppress Host Defenses

(2020) Abhik K. Banerjee et al.   CELL

Identification of required host factors for SARS-CoV-2 infection in human cells

(2020) Zharko Daniloski et al.   CELL

Genome-wide CRISPR screens reveal host factors critical for SARS-CoV-2 infection

(2020) Jin Wei et al.   CELL

Mechanism and inhibition of the papain‐like protease, PLpro, of SARS‐CoV‐2

(2020) Theresa Klemm et al.   EMBO JOURNAL

Association Between Administration of Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19

(2020) et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

IL-6 serum levels predict severity and response to tocilizumab in COVID-19: An observational study

(2020) José María Galván-Román et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Type I interferon susceptibility distinguishes SARS-CoV-2 from SARS-CoV.

(2020) Kumari G. Lokugamage et al.   JOURNAL OF VIROLOGY

The coding capacity of SARS-CoV-2

(2020) Yaara Finkel et al.   NATURE

SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation

(2020) Katharina Schubert et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling

(2020) Lisa Miorin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

(2020) Qian Zhang et al.   SCIENCE

Autoantibodies against type I IFNs in patients with life-threatening COVID-19

(2020) Paul Bastard et al.   SCIENCE

Evasion of Type I Interferon by SARS-CoV-2

(2020) Hongjie Xia et al.   Cell Reports

SARS-CoV-2 ORF3b Is a Potent Interferon Antagonist Whose Activity Is Increased by a Naturally Occurring Elongation Variant

(2020) Yoriyuki Konno et al.   Cell Reports

Overexpression of SARS-CoV-2 protein ORF6 dislocates RAE1 and NUP98 from the nuclear pore complex

(2020) Koki Kato et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cryo-EM Structure of an Extended SARS-CoV-2 Replication and Transcription Complex Reveals an Intermediate State in Cap Synthesis

(2020) Liming Yan et al.   CELL

Inflammasomes are activated in response to SARS-CoV-2 infection and are associated with COVID-19 severity in patients

(2020) Tamara S. Rodrigues et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Structural insights into SARS-CoV-2 proteins

(2020) Rimanshee Arya et al.   JOURNAL OF MOLECULAR BIOLOGY

Nonstructural Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity Factor Redirecting Host Protein Synthesis Machinery toward Viral RNA

(2020) Shuai Yuan et al.   MOLECULAR CELL

Genomic RNA Elements Drive Phase Separation of the SARS-CoV-2 Nucleocapsid

(2020) Christiane Iserman et al.   MOLECULAR CELL

Genetic mechanisms of critical illness in Covid-19

(2020) Erola Pairo-Castineira et al.   NATURE

Baricitinib plus Remdesivir for Hospitalized Adults with Covid-19

(2020) Andre C. Kalil et al.   NEW ENGLAND JOURNAL OF MEDICINE

Tocilizumab in Patients Hospitalized with Covid-19 Pneumonia

(2020) Carlos Salama et al.   NEW ENGLAND JOURNAL OF MEDICINE

The viral protein NSP1 acts as a ribosome gatekeeper for shutting down host translation and fostering SARS-CoV-2 translation

(2020) Antonin TIDU et al.   RNA

SARS-CoV-2 Nucleocapsid Protein Interacts with RIG-I and Represses RIG-Mediated IFN-β Production

(2020) Keli Chen et al.   Viruses-Basel

STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters

(2020) Robbert Boudewijns et al.   Nature Communications

Nucleocapsid protein of SARS-CoV-2 phase separates into RNA-rich polymerase-containing condensates

(2020) Adriana Savastano et al.   Nature Communications

SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species.

(2020) Mehdi Moustaqil et al.   Emerging Microbes & Infections

ISG15: It's Complicated

(2019) John V. Dzimianski et al.   JOURNAL OF MOLECULAR BIOLOGY

Ubiquitin-Dependent and -Independent Roles of E3 Ligase RIPLET in Innate Immunity

(2019) Cristhian Cadena et al.   CELL

Shared and Distinct Functions of Type I and Type III Interferons

(2019) Helen M. Lazear et al.   IMMUNITY

A molecular switch from STAT2-IRF9 to ISGF3 underlies interferon-induced gene transcription

(2019) Ekaterini Platanitis et al.   Nature Communications

Translational Control in Virus-Infected Cells

(2018) Noam Stern-Ginossar et al.   Cold Spring Harbor Perspectives in Biology

Innate Sensing of DNA Virus Genomes

(2018) Zhe Ma et al.   Annual Review of Virology

Origin and evolution of pathogenic coronaviruses

(2018) Jie Cui et al.   NATURE REVIEWS MICROBIOLOGY

The hidden burden of influenza: A review of the extra-pulmonary complications of influenza infection

(2017) Subhashini A. Sellers et al.   Influenza and Other Respiratory Viruses

Expression and Cleavage of Middle East Respiratory Syndrome Coronavirus nsp3-4 Polyprotein Induce the Formation of Double-Membrane Vesicles That Mimic Those Associated with Coronaviral RNA Replication

(2017) Diede Oudshoorn et al.   mBio

Recent loss of closed forests is associated with Ebola virus disease outbreaks

(2017) Jesús Olivero et al.   Scientific Reports

The Evolution of Antiviral Defense Systems

(2016) Benjamin R. tenOever   Cell Host & Microbe

The Anthropocene is functionally and stratigraphically distinct from the Holocene

(2016) C. N. Waters et al.   SCIENCE

Components and regulation of nuclear transport processes

(2014) Bastien Cautain et al.   FEBS Journal

Type I IFN-Mediated Protection of Macrophages and Dendritic Cells Secures Control of Murine Coronavirus Infection

(2014) L. Cervantes-Barragan et al.   JOURNAL OF IMMUNOLOGY

A day in the life of the spliceosome

(2014) A. Gregory Matera et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Nidovirus papain-like proteases: Multifunctional enzymes with protease, deubiquitinating and deISGylating activities

(2014) Anna M. Mielech et al.   VIRUS RESEARCH

Evidence for henipavirus spillover into human populations in Africa

(2014) Olivier Pernet et al.   Nature Communications

Signal Recognition Particle: An Essential Protein-Targeting Machine

(2013) David Akopian et al.   Annual Review of Biochemistry

Toll-Like Receptors in Antiviral Innate Immunity

(2013) Sandra N. Lester et al.   JOURNAL OF MOLECULAR BIOLOGY

Severe Acute Respiratory Syndrome Coronavirus Nonstructural Proteins 3, 4, and 6 Induce Double-Membrane Vesicles

(2013) M. M. Angelini et al.   mBio

Origins of HIV and the AIDS Pandemic

(2013) P. M. Sharp et al.   Cold Spring Harbor Perspectives in Medicine

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

Mechanisms of mRNA translation of interferon stimulated genes

(2010) Sonali Joshi et al.   CYTOKINE

Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses

(2009) T. H. Mogensen   CLINICAL MICROBIOLOGY REVIEWS

The roles of TLRs, RLRs and NLRs in pathogen recognition

(2009) T. Kawai et al.   INTERNATIONAL IMMUNOLOGY

A two-pronged strategy to suppress host protein synthesis by SARS coronavirus Nsp1 protein

(2009) Wataru Kamitani et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Functional screen reveals SARS coronavirus nonstructural protein nsp14 as a novel cap N7 methyltransferase

(2009) Y. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epidemic Dynamics at the Human-Animal Interface

(2009) J. O. Lloyd-Smith et al.   SCIENCE

Coronavirus Nonstructural Protein 16 Is a Cap-0 Binding Enzyme Possessing (Nucleoside-2'O)-Methyltransferase Activity

(2008) E. Decroly et al.   JOURNAL OF VIROLOGY