Components and regulation of nuclear transport processes

Targeting nucleocytoplasmic transport in cancer therapy

(2015) Richard Hill et al.   Oncotarget

Prediction of nuclear export signals using weighted regular expressions (Wregex)

(2014) Gorka Prieto et al.   BIOINFORMATICS

Nuclear Trafficking in Health and Disease

(2014) Amir Mor et al.   CURRENT OPINION IN CELL BIOLOGY

NESmapper: Accurate Prediction of Leucine-Rich Nuclear Export Signals Using Activity-Based Profiles

(2014) Shunichi Kosugi et al.   PLoS Computational Biology

Integrated Structural Analysis of the Human Nuclear Pore Complex Scaffold

(2013) Khanh Huy Bui et al.   CELL

Dynamic trafficking of STAT5 depends on an unconventional nuclear localization signal

(2013) H. Y. Shin et al.   JOURNAL OF CELL SCIENCE

Functional Architecture of the Nuclear Pore Complex

(2012) Einat Grossman et al.   Annual Review of Biophysics

Nuclear trafficking of proteins from RNA viruses: Potential target for antivirals?

(2012) Leon Caly et al.   ANTIVIRAL RESEARCH

Nuclear Envelope Budding Enables Large Ribonucleoprotein Particle Export during Synaptic Wnt Signaling

(2012) Sean D. Speese et al.   CELL

Herpes Simplex Virus ICP27 Protein Directly Interacts with the Nuclear Pore Complex through Nup62, Inhibiting Host Nucleocytoplasmic Transport Pathways

(2012) Poonam Malik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NESdb: a database of NES-containing CRM1 cargoes

(2012) Darui Xu et al.   MOLECULAR BIOLOGY OF THE CELL

ValidNESs: a database of validated leucine-rich nuclear export signals

(2012) Szu-Chin Fu et al.   NUCLEIC ACIDS RESEARCH

The Human Nuclear Pore Complex as Revealed by Cryo-Electron Tomography

(2012) Tal Maimon et al.   STRUCTURE

Moving to the Core: Spatiotemporal Analysis of Forkhead Box O (FOXO) and Nuclear Factor-κB (NF-κB) Nuclear Translocation

(2012) Fabian Zanella et al.   TRAFFIC

The Structure of the Nuclear Pore Complex

(2011) André Hoelz et al.   Annual Review of Biochemistry

Nuclear export of proteins and drug resistance in cancer

(2011) Joel G. Turner et al.   BIOCHEMICAL PHARMACOLOGY

New clues to understand the role of THO and other functionally related factors in mRNP biogenesis

(2011) Rosa Luna et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

mRNA export and the TREX complex

(2011) Jun Katahira   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Linking gene regulation to mRNA production and export

(2011) Susana Rodríguez-Navarro et al.   CURRENT OPINION IN CELL BIOLOGY

Protein localization in disease and therapy

(2011) M.-C. Hung et al.   JOURNAL OF CELL SCIENCE

The Ebola Virus VP24 Protein Prevents hnRNP C1/C2 Binding to Karyopherin α1 and Partially Alters its Nuclear Import

(2011) Reed S. Shabman et al.   JOURNAL OF INFECTIOUS DISEASES

Differential Processing of Nuclear Pore Complex Proteins by Rhinovirus 2A Proteases from Different Species and Serotypes

(2011) K. Watters et al.   JOURNAL OF VIROLOGY

Prediction of leucine-rich nuclear export signal containing proteins with NESsential

(2011) Szu-Chin Fu et al.   NUCLEIC ACIDS RESEARCH

Calcium regulation of nucleocytoplasmic transport

(2011) Ashapurna Sarma et al.   Protein & Cell

mRNA export and cancer

(2011) Nadeem Siddiqui et al.   Wiley Interdisciplinary Reviews-RNA

Nuclear import by karyopherin-βs: Recognition and inhibition

(2010) Yuh Min Chook et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Molecular basis for specificity of nuclear import and prediction of nuclear localization

(2010) Mary Marfori et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Recognition of nuclear targeting signals by Karyopherin-β proteins

(2010) Darui Xu et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Protein Tpr is required for establishing nuclear pore-associated zones of heterochromatin exclusion

(2010) Sandra Krull et al.   EMBO JOURNAL

Pom121 links two essential subcomplexes of the nuclear pore complex core to the membrane

(2010) Jana M. Mitchell et al.   JOURNAL OF CELL BIOLOGY

Mechanistic Consequences of hnRNP C Binding to Both RNA Termini of Poliovirus Negative-Strand RNA Intermediates

(2010) K. J. Ertel et al.   JOURNAL OF VIROLOGY

Nuclear Import Mechanism of the EJC Component Mago-Y14 Revealed by Structural Studies of Importin 13

(2010) Fulvia Bono et al.   MOLECULAR CELL

The nuclear pore complex: bridging nuclear transport and gene regulation

(2010) Caterina Strambio-De-Castillia et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1

(2010) Thomas Güttler et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Comparative Genomic Evidence for a Complete Nuclear Pore Complex in the Last Eukaryotic Common Ancestor

(2010) Nadja Neumann et al.   PLoS One

Structural and functional analysis of the interaction between the nucleoporin Nup98 and the mRNA export factor Rae1

(2010) Y. Ren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of the nuclear envelope in genome organization and gene expression

(2010) David W. Van de Vosse et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

A Protein Inventory of Human Ribosome Biogenesis Reveals an Essential Function of Exportin 5 in 60S Subunit Export

(2010) Thomas Wild et al.   PLOS BIOLOGY

First and last ancestors: reconstructing evolution of the endomembrane system with ESCRTs, vesicle coat proteins, and nuclear pore complexes

(2009) Mark C Field et al.   CURRENT OPINION IN CELL BIOLOGY

Kap104p Imports the PY-NLS-containing Transcription Factor Tfg2p into the Nucleus

(2009) Katherine E. Süel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exportin 4 mediates a novel nuclear import pathway for Sox family transcription factors

(2009) Cristina Gontan et al.   JOURNAL OF CELL BIOLOGY

mRNA nuclear export at a glance

(2009) S. R. Carmody et al.   JOURNAL OF CELL SCIENCE

RNA nuclear export is blocked by poliovirus 2A protease and is concomitant with nucleoporin cleavage

(2009) A. Castello et al.   JOURNAL OF CELL SCIENCE

Rhinovirus 3C Protease Can Localize in the Nucleus and Alter Active and Passive Nucleocytoplasmic Transport

(2009) R. Ghildyal et al.   JOURNAL OF VIROLOGY

Mengovirus-Induced Rearrangement of the Nuclear Pore Complex: Hijacking Cellular Phosphorylation Machinery

(2009) M. V. Bardina et al.   JOURNAL OF VIROLOGY

Ebolavirus VP24 Binding to Karyopherins Is Required for Inhibition of Interferon Signaling

(2009) M. Mateo et al.   JOURNAL OF VIROLOGY

Structural basis for leucine-rich nuclear export signal recognition by CRM1

(2009) Xiuhua Dong et al.   NATURE

Structural basis for assembly and disassembly of the CRM1 nuclear export complex

(2009) Xiuhua Dong et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Crystal Structure of the Nuclear Export Receptor CRM1 in Complex with Snurportin1 and RanGTP

(2009) T. Monecke et al.   SCIENCE

Importins and Beyond: Non-Conventional Nuclear Transport Mechanisms

(2009) Kylie M. Wagstaff et al.   TRAFFIC

Expanding the Definition of the Classical Bipartite Nuclear Localization Signal

(2009) Allison Lange et al.   TRAFFIC

The SR protein family of splicing factors: master regulators of gene expression

(2008) Jennifer C. Long et al.   BIOCHEMICAL JOURNAL

Depletion of nucleophosmin via transglutaminase 2 cross-linking increases drug resistance in cancer cells

(2008) Kang-Seo Park et al.   CANCER LETTERS

Design of Peptide Inhibitors for the Importin α/β Nuclear Import Pathway by Activity-Based Profiling

(2008) Shunichi Kosugi et al.   CHEMISTRY & BIOLOGY

CRM1-Mediated Nuclear Export of Proteins and Drug Resistance in Cancer

(2008) Joel Turner et al.   CURRENT MEDICINAL CHEMISTRY

Thyroid Hormone Receptor α1 Follows a Cooperative CRM1/Calreticulin-mediated Nuclear Export Pathway

(2008) Matthew E. Grespin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A PY-NLS Nuclear Targeting Signal Is Required for Nuclear Localization and Function of theSaccharomyces cerevisiaemRNA-binding Protein Hrp1

(2008) Allison Lange et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Severe Acute Respiratory Syndrome Coronavirus Protein 6 Accelerates Murine Hepatitis Virus Infections by More than One Mechanism

(2008) S. Hussain et al.   JOURNAL OF VIROLOGY

Leader-Induced Phosphorylation of Nucleoporins Correlates with Nuclear Trafficking Inhibition by Cardioviruses

(2008) F. W. Porter et al.   JOURNAL OF VIROLOGY

STRADα Regulates LKB1 Localization by Blocking Access to Importin-α, and by Association with Crm1 and Exportin-7

(2008) Julia Dorfman et al.   MOLECULAR BIOLOGY OF THE CELL

A Fence-like Coat for the Nuclear Pore Membrane

(2008) Erik W. Debler et al.   MOLECULAR CELL

Nuclear Export Signal Consensus Sequences Defined Using a Localization-Based Yeast Selection System

(2008) Shunichi Kosugi et al.   TRAFFIC