SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation
Authors
Keywords
-
Journal
NATURE STRUCTURAL & MOLECULAR BIOLOGY
Volume 27, Issue 10, Pages 959-966
Publisher
Springer Science and Business Media LLC
Online
2020-09-10
DOI
10.1038/s41594-020-0511-8
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Genomic variance of the 2019‐nCoV coronavirus
- (2020) Carmine Ceraolo et al. JOURNAL OF MEDICAL VIROLOGY
- The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2
- (2020) Nature Microbiology
- The Architecture of SARS-CoV-2 Transcriptome
- (2020) Dongwan Kim et al. CELL
- RNA genome conservation and secondary structure in SARS-CoV-2 and SARS-related viruses: a first look
- (2020) Ramya Rangan et al. RNA
- Structural Insights into the Mammalian Late-Stage Initiation Complexes
- (2020) Angelita Simonetti et al. Cell Reports
- Identification of potential drugs against SARS-CoV-2 non-structural protein 1 (nsp1)
- (2020) Gabriela de Lima Menezes et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2
- (2020) Matthias Thoms et al. SCIENCE
- Human NMD ensues independently of stable ribosome stalling
- (2020) Evangelos D. Karousis et al. Nature Communications
- Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix
- (2019) Dorothee Liebschner et al. Acta Crystallographica Section D-Structural Biology
- Characterisation of molecular motions in cryo-EM single-particle data by multi-body refinement in RELION
- (2018) Takanori Nakane et al. eLife
- Structures of translationally inactive mammalian ribosomes
- (2018) Alan Brown et al. eLife
- Structural and Functional Insights into Human Re-initiation Complexes
- (2017) Melanie Weisser et al. MOLECULAR CELL
- MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy
- (2017) Shawn Q Zheng et al. NATURE METHODS
- cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination
- (2017) Ali Punjani et al. NATURE METHODS
- Gctf: Real-time CTF determination and correction
- (2016) Kai Zhang JOURNAL OF STRUCTURAL BIOLOGY
- Middle East Respiratory Syndrome Coronavirus nsp1 Inhibits Host Gene Expression by Selectively Targeting mRNAs Transcribed in the Nucleus while Sparing mRNAs of Cytoplasmic Origin
- (2015) Kumari G. Lokugamage et al. JOURNAL OF VIROLOGY
- Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex
- (2015) Jose L. Llácer et al. MOLECULAR CELL
- The Phyre2 web portal for protein modeling, prediction and analysis
- (2015) Lawrence A Kelley et al. Nature Protocols
- The structure and functions of coronavirus genomic 3′ and 5′ ends
- (2015) Dong Yang et al. VIRUS RESEARCH
- Structures of the human and Drosophila 80S ribosome
- (2013) Andreas M. Anger et al. NATURE
- Severe Acute Respiratory Syndrome Coronavirus Protein nsp1 Is a Novel Eukaryotic Translation Inhibitor That Represses Multiple Steps of Translation Initiation
- (2012) K. G. Lokugamage et al. JOURNAL OF VIROLOGY
- Prevention of overfitting in cryo-EM structure determination
- (2012) Sjors H W Scheres et al. NATURE METHODS
- SARS Coronavirus nsp1 Protein Induces Template-Dependent Endonucleolytic Cleavage of mRNAs: Viral mRNAs Are Resistant to nsp1-Induced RNA Cleavage
- (2011) Cheng Huang et al. PLoS Pathogens
- Features and development ofCoot
- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- MolProbity: all-atom structure validation for macromolecular crystallography
- (2009) Vincent B. Chen et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- A two-pronged strategy to suppress host protein synthesis by SARS coronavirus Nsp1 protein
- (2009) Wataru Kamitani et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Severe Acute Respiratory Syndrome Coronavirus nsp1 Suppresses Host Gene Expression, Including That of Type I Interferon, in Infected Cells
- (2008) K. Narayanan et al. JOURNAL OF VIROLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started