Genomic RNA Elements Drive Phase Separation of the SARS-CoV-2 Nucleocapsid
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Genomic RNA Elements Drive Phase Separation of the SARS-CoV-2 Nucleocapsid
Authors
Keywords
SARS-CoV-2, Condensation, phase separation, packaging, RNP-MaP, RNA structure, nucleocapsid, coronavirus
Journal
MOLECULAR CELL
Volume 80, Issue 6, Pages 1078-1091.e6
Publisher
Elsevier BV
Online
2020-11-27
DOI
10.1016/j.molcel.2020.11.041
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- SciPy 1.0: fundamental algorithms for scientific computing in Python
- (2020) Pauli Virtanen et al. NATURE METHODS
- Valence and patterning of aromatic residues determine the phase behavior of prion-like domains
- (2020) Erik W. Martin et al. SCIENCE
- Condensation of Ded1p Promotes a Translational Switch from Housekeeping to Stress Protein Production
- (2020) Christiane Iserman et al. CELL
- The Architecture of SARS-CoV-2 Transcriptome
- (2020) Dongwan Kim et al. CELL
- RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation
- (2020) Jordina Guillén-Boixet et al. CELL
- SARS-CoV-2 (COVID-19) by the numbers
- (2020) Yinon M Bar-On et al. eLife
- Measles virus nucleo- and phosphoproteins form liquid-like phase-separated compartments that promote nucleocapsid assembly
- (2020) Serafima Guseva et al. Science Advances
- Crystal structure of SARS-CoV-2 nucleocapsid protein RNA binding domain reveals potential unique drug targeting sites
- (2020) Sisi Kang et al. Acta Pharmaceutica Sinica B
- Analysis of RNA–protein networks with RNP-MaP defines functional hubs on RNA
- (2020) Chase A. Weidmann et al. NATURE BIOTECHNOLOGY
- Phosphoregulation of Phase Separation by the SARS-CoV-2 N Protein Suggests a Biophysical Basis for its Dual Functions
- (2020) Christopher R. Carlson et al. MOLECULAR CELL
- Spontaneous driving forces give rise to protein−RNA condensates with coexisting phases and complex material properties
- (2019) Steven Boeynaems et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Guidelines for SHAPE Reagent Choice and Detection Strategy for RNA Structure Probing Studies
- (2019) Steven Busan et al. BIOCHEMISTRY
- Influenza A virus ribonucleoproteins form liquid organelles at endoplasmic reticulum exit sites
- (2019) Marta Alenquer et al. Nature Communications
- Software for lattice light-sheet imaging of FRET biosensors, illustrated with a new Rap1 biosensor
- (2019) Ellen C. O’Shaughnessy et al. JOURNAL OF CELL BIOLOGY
- RNA base-pairing complexity in living cells visualized by correlated chemical probing
- (2019) Anthony M. Mustoe et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Coronavirus genomic RNA packaging
- (2019) Paul S. Masters VIROLOGY
- Functional Implications of Intracellular Phase Transitions
- (2018) Alex S. Holehouse et al. BIOCHEMISTRY
- A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins
- (2018) Jie Wang et al. CELL
- Post-translational modifications of coronavirus proteins: roles and function
- (2018) To Sing Fung et al. Future Virology
- Ubiquitin Modulates Liquid-Liquid Phase Separation of UBQLN2 via Disruption of Multivalent Interactions
- (2018) Thuy P. Dao et al. MOLECULAR CELL
- Physical principles of intracellular organization via active and passive phase transitions
- (2018) Joel Berry et al. REPORTS ON PROGRESS IN PHYSICS
- RNA buffers the phase separation behavior of prion-like RNA binding proteins
- (2018) Shovamayee Maharana et al. SCIENCE
- mRNA structure determines specificity of a polyQ-driven phase separation
- (2018) Erin M. Langdon et al. SCIENCE
- Phase Transitions Drive the Formation of Vesicular Stomatitis Virus Replication Compartments
- (2018) Bianca S. Heinrich et al. mBio
- A persistently infecting coronavirus in hibernating Myotis lucifugus, the North American little brown bat
- (2017) Sonu Subudhi et al. JOURNAL OF GENERAL VIROLOGY
- Prediction of protein disorder based on IUPred
- (2017) Zsuzsanna Dosztányi PROTEIN SCIENCE
- Accurate detection of chemical modifications in RNA by mutational profiling (MaP) with ShapeMapper 2
- (2017) Steven Busan et al. RNA
- Negri bodies are viral factories with properties of liquid organelles
- (2017) Jovan Nikolic et al. Nature Communications
- Functional organization of cytoplasmic inclusion bodies in cells infected by respiratory syncytial virus
- (2017) Vincent Rincheval et al. Nature Communications
- Coronavirus nucleocapsid proteins assemble constitutively in high molecular oligomers
- (2017) Yingying Cong et al. Scientific Reports
- RNA-Based Coacervates as a Model for Membraneless Organelles: Formation, Properties, and Interfacial Liposome Assembly
- (2016) William M. Aumiller et al. LANGMUIR
- Sequence Determinants of Intracellular Phase Separation by Complex Coacervation of a Disordered Protein
- (2016) Chi W. Pak et al. MOLECULAR CELL
- Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization
- (2015) Amandine Molliex et al. CELL
- A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
- (2015) Avinash Patel et al. CELL
- Phase Transition of Spindle-Associated Protein Regulate Spindle Apparatus Assembly
- (2015) Hao Jiang et al. CELL
- RNA Controls PolyQ Protein Phase Transitions
- (2015) Huaiying Zhang et al. MOLECULAR CELL
- Phase Transition of a Disordered Nuage Protein Generates Environmentally Responsive Membraneless Organelles
- (2015) Timothy J. Nott et al. MOLECULAR CELL
- Sequence heuristics to encode phase behaviour in intrinsically disordered protein polymers
- (2015) Felipe García Quiroz et al. NATURE MATERIALS
- Selective 2′-hydroxyl acylation analyzed by primer extension and mutational profiling (SHAPE-MaP) for direct, versatile and accurate RNA structure analysis
- (2015) Matthew J Smola et al. Nature Protocols
- The disordered P granule protein LAF-1 drives phase separation into droplets with tunable viscosity and dynamics
- (2015) Shana Elbaum-Garfinkle et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- FRESCo: finding regions of excess synonymous constraint in diverse viruses
- (2015) Rachel S Sealfon et al. GENOME BIOLOGY
- RAxML version 8: a tool for phylogenetic analysis and post-analysis of large phylogenies
- (2014) Alexandros Stamatakis BIOINFORMATICS
- Molecular Description of the LCST Behavior of an Elastin-Like Polypeptide
- (2014) Nan K. Li et al. BIOMACROMOLECULES
- RNA motif discovery by SHAPE and mutational profiling (SHAPE-MaP)
- (2014) Nathan A Siegfried et al. NATURE METHODS
- The Coronavirus Nucleocapsid Is a Multifunctional Protein
- (2014) Ruth McBride et al. Viruses-Basel
- Functional Analysis of the Murine Coronavirus Genomic RNA Packaging Signal
- (2013) L. Kuo et al. JOURNAL OF VIROLOGY
- Transmissible Gastroenteritis Coronavirus Genome Packaging Signal Is Located at the 5' End of the Genome and Promotes Viral RNA Incorporation into Virions in a Replication-Independent Process
- (2013) L. Morales et al. JOURNAL OF VIROLOGY
- NIH Image to ImageJ: 25 years of image analysis
- (2012) Caroline A Schneider et al. NATURE METHODS
- Ultrastructural Characterization of Arterivirus Replication Structures: Reshaping the Endoplasmic Reticulum To Accommodate Viral RNA Synthesis
- (2011) K. Knoops et al. JOURNAL OF VIROLOGY
- Integrative genomics viewer
- (2011) James T Robinson et al. NATURE BIOTECHNOLOGY
- Organelle-Like Membrane Compartmentalization of Positive-Strand RNA Virus Replication Factories
- (2010) Johan A. den Boon et al. Annual Review of Microbiology
- RNAstructure: software for RNA secondary structure prediction and analysis
- (2010) Jessica S Reuter et al. BMC BIOINFORMATICS
- The Coronavirus Nucleocapsid Protein Is Dynamically Associated with the Replication-Transcription Complexes
- (2010) M. H. Verheije et al. JOURNAL OF VIROLOGY
- VARNA: Interactive drawing and editing of the RNA secondary structure
- (2009) Kévin Darty et al. BIOINFORMATICS
- Coronavirus N Protein N-Terminal Domain (NTD) Specifically Binds the Transcriptional Regulatory Sequence (TRS) and Melts TRS-cTRS RNA Duplexes
- (2009) Nicholas E. Grossoehme et al. JOURNAL OF MOLECULAR BIOLOGY
- Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation
- (2009) C. P. Brangwynne et al. SCIENCE
- Phosphorylation of the arginine/serine dipeptide-rich motif of the severe acute respiratory syndrome coronavirus nucleocapsid protein modulates its multimerization, translation inhibitory activity and cellular localization
- (2008) Tsui-Yi Peng et al. FEBS Journal
- Glycogen Synthase Kinase-3 Regulates the Phosphorylation of Severe Acute Respiratory Syndrome Coronavirus Nucleocapsid Protein and Viral Replication
- (2008) Chia-Hsin Wu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now