Inflammasomes are activated in response to SARS-CoV-2 infection and are associated with COVID-19 severity in patients

Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR

(2020) Victor M Corman et al.   Eurosurveillance

Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China

(2020) Zunyou Wu et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China

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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

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Comparative Performance of SARS-CoV-2 Detection Assays Using Seven Different Primer-Probe Sets and One Assay Kit

(2020) Arun K. Nalla et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Immune cell profiling of COVID-19 patients in the recovery stage by single-cell sequencing

(2020) Wen Wen et al.   Cell Discovery

Lactate dehydrogenase, an independent risk factor of severe COVID-19 patients: a retrospective and observational study

(2020) Yi Han et al.   Aging-US

Serum Cytokine and Chemokine Profile in Relation to the Severity of Coronavirus Disease 2019 in China

(2020) Ying Chi et al.   JOURNAL OF INFECTIOUS DISEASES

Longitudinal analyses reveal immunological misfiring in severe COVID-19

(2020) Carolina Lucas et al.   NATURE

Priming Is Dispensable for NLRP3 Inflammasome Activation in Human Monocytes In Vitro

(2020) Anna Gritsenko et al.   Frontiers in Immunology

Yellow Fever-Induced Acute Lung Injury

(2019) Alexandre Todorovic Fabro et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The hierarchical structural architecture of inflammasomes, supramolecular inflammatory machines

(2015) Arthur V Hauenstein et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

The Th17 pathway in the peripheral lung microenvironment interacts with expression of collagen V in the late state of experimental pulmonary fibrosis

(2015) Alexandre T. Fabro et al.   IMMUNOBIOLOGY

Neutrophil Elastase Promotes Interleukin-1β Secretion from Human Coronary Endothelium

(2015) Mabruka Alfaidi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

(2015) Rebecca C Coll et al.   NATURE MEDICINE

The adaptor ASC exacerbates lethalListeria monocytogenesinfection by mediating IL-18 production in an inflammasome-dependent and -independent manner

(2014) Kohsuke Tsuchiya et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Caspase 1–independent activation of interleukin-1β in neutrophil-predominant inflammation

(2009) Monica Guma et al.   ARTHRITIS AND RHEUMATISM

Inflammatory arthritis in caspase 1 gene–deficient mice: Contribution of proteinase 3 to caspase 1–independent production of bioactive interleukin-1β

(2009) Leo A. B. Joosten et al.   ARTHRITIS AND RHEUMATISM

Differential requirement for the activation of the inflammasome for processing and release of IL-1  in monocytes and macrophages

(2008) M. G. Netea et al.   BLOOD