Molecular Mechanisms Related to Responses to Oxidative Stress and Antioxidative Therapies in COVID-19: A Systematic Review

Alzheimer's‐like signaling in brains of COVID‐19 patients

(2022) Steve Reiken et al.   Alzheimers & Dementia

Exploring Structural Mechanism of COVID-19 Treatment with Glutathione as a Potential Peptide Inhibitor to the Main Protease: Molecular Dynamics Simulation and MM/PBSA Free Energy Calculations Study

(2022) Abderahmane Linani et al.   International Journal of Peptide Research and Therapeutics

Oxidative stress and decreased Nrf2 level in pediatric patients with COVID‐19

(2022) Hüseyin Gümüş et al.   JOURNAL OF MEDICAL VIROLOGY

Gut Microbiome and Diet in Populations with Obesity: Role of the Na+/K+‐ATPase Transporter Signaling in Severe COVID‐19

(2022) Zeid J. Khitan¹ et al.   Obesity

Superoxide Dismutase Prevents SARS-CoV-2-Induced Plasma Cell Apoptosis and Stabilizes Specific Antibody Induction

(2022) Li-Hua Mo et al.   Oxidative Medicine and Cellular Longevity

Thiol-based chemical probes exhibit antiviral activity against SARS-CoV-2 via allosteric disulfide disruption in the spike glycoprotein

(2022) Yunlong Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-Wide Characterization of SARS-CoV-2 Cytopathogenic Proteins in the Search of Antiviral Targets

(2022) Jiantao Zhang et al.   mBio

Persistent Oxidative Stress and Inflammasome Activation in CD14highCD16− Monocytes From COVID-19 Patients

(2022) Silvia Lucena Lage et al.   Frontiers in Immunology

Use of N-Acetylcysteine at high doses as an oral treatment for patients hospitalized with COVID-19

(2022) José Luis Izquierdo et al.   SCIENCE PROGRESS

Potential and Possible Therapeutic Effects of Melatonin on SARS-CoV-2 Infection

(2022) Evgeny Shchetinin et al.   Antioxidants

The function of SARS-CoV-2 spike protein is impaired by disulfide-bond disruption with mutation at cysteine-488 and by thiol-reactive N-acetyl-cysteine and glutathione

(2022) Mana Murae et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Ex-vivo mucolytic and anti-inflammatory activity of BromAc in tracheal aspirates from COVID-19

(2022) Jordana Grazziela A. Coelho dos Reis et al.   BIOMEDICINE & PHARMACOTHERAPY

Antioxidant, anti-inflammatory and immunomodulatory roles of vitamins in COVID-19 therapy

(2022) Aurelia Magdalena Pisoschi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Oxidative stress and inflammatory markers in patients with COVID-19: Potential role of RAGE, HMGB1, GFAP and COX-2 in disease severity

(2022) Fabiolla Rocha Santos Passos et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Lung targeted liposomes for treating ARDS

(2022) Sivan Arber Raviv et al.   JOURNAL OF CONTROLLED RELEASE

SOD2 rs4880 and GPX1 rs1050450 polymorphisms do not confer risk of COVID-19, but influence inflammation or coagulation parameters in Serbian cohort

(2022) Djurdja Jerotic et al.   REDOX REPORT

GlyNAC (Glycine and N-Acetylcysteine) Supplementation in Mice Increases Length of Life by Correcting Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Abnormalities in Mitophagy and Nutrient Sensing, and Genomic Damage

(2022) Premranjan Kumar et al.   Nutrients

Oxidative Stress and Inflammatory Status in COVID-19 Outpatients: A Health Center-Based Analytical Cross-Sectional Study

(2022) Sahar Golabi et al.   Antioxidants

Reactive Sulfur Compounds in the Fight against COVID-19

(2022) Małgorzata Iciek et al.   Antioxidants

Effects of Different Inhalation Therapy on Ventilator-Associated Pneumonia in Ventilated COVID-19 Patients: A Randomized Controlled Trial

(2022) Nikola Delić et al.   Microorganisms

Intravenous N-Acetylcysteine in Management of COVID-19: A Case Series

(2022) Brandon Chen et al.   JOURNAL OF PHARMACY PRACTICE

How to Restore Oxidative Balance That Was Disrupted by SARS-CoV-2 Infection

(2022) Kajetan Kiełbowski et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

G6PD deficiency and severity of COVID19 pneumonia and acute respiratory distress syndrome: tip of the iceberg?

(2021) Jihad G. Youssef et al.   ANNALS OF HEMATOLOGY

Associations between COVID-19 and skin conditions identified through epidemiology and genomic studies

(2021) Matthew T. Patrick et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

NOX-Dependent Signaling Dysregulation in Severe COVID-19: Clues to Effective Treatments

(2021) Simona Damiano et al.   Frontiers in Cellular and Infection Microbiology

Commentary: Paracetamol-Induced Glutathione Consumption: Is There a Link With Severe COVID-19 Illness?

(2021) Sergio Verd et al.   Frontiers in Pharmacology

COVID-19 and the human innate immune system

(2021) Joachim L. Schultze et al.   CELL

Evidence for CAT gene being functionally involved in the susceptibility of COVID‐19

(2021) Yu Qian et al.   FASEB JOURNAL

Susceptibility of the patients infected with Sars-Cov2 to oxidative stress and possible interplay with severity of the disease

(2021) Ana C. Gadotti et al.   FREE RADICAL BIOLOGY AND MEDICINE

Pharmacogenomics and COVID-19: clinical implications of human genome interactions with repurposed drugs

(2021) Osama A. Badary   PHARMACOGENOMICS JOURNAL

COVID-19 and male reproductive function: a prospective, longitudinal cohort study

(2021) Behzad Hajizadeh Maleki et al.   REPRODUCTION

Oxidative Stress Status in COVID-19 Patients Hospitalized in Intensive Care Unit for Severe Pneumonia. A Pilot Study

(2021) Joël Pincemail et al.   Antioxidants

Human gene polymorphisms and their possible impact on the clinical outcome of SARS-CoV-2 infection

(2021) Seyed Mohammad Ali Hashemi et al.   ARCHIVES OF VIROLOGY

A useful and sensitive marker in the prediction of COVID-19 and disease severity: Thiol

(2021) Ayse Kaya Kalem et al.   FREE RADICAL BIOLOGY AND MEDICINE

Integrative Genomics Analysis Reveals a 21q22.11 Locus Contributing Risk to COVID-19

(2021) Yunlong Ma et al.   HUMAN MOLECULAR GENETICS

Longitudinal analysis reveals that delayed bystander CD8+ T cell activation and early immune pathology distinguish severe COVID-19 from mild disease.

(2021) Laura Bergamaschi et al.   IMMUNITY

Association of GSTM1 and GSTT1 gene polymorphisms with COVID‐19 susceptibility and its outcome

(2021) Mohammad Abbas et al.   JOURNAL OF MEDICAL VIROLOGY

Superoxide Dismutase Administration: A Review of Proposed Human Uses

(2021) Arianna Carolina Rosa et al.   MOLECULES

Trans-ancestry analysis reveals genetic and nongenetic associations with COVID-19 susceptibility and severity

(2021) Janie F. Shelton et al.   NATURE GENETICS

Predicting Severity and Intrahospital Mortality in COVID-19: The Place and Role of Oxidative Stress

(2021) Ivan Cekerevac et al.   Oxidative Medicine and Cellular Longevity

The PRISMA 2020 statement: an updated guideline for reporting systematic reviews

(2021) Matthew J Page et al.   BMJ-British Medical Journal

Curcumin as a Potential Treatment for COVID-19

(2021) Bruna A. C. Rattis et al.   Frontiers in Pharmacology

The Efficacy of Antioxidant Oral Supplements on the Progression of COVID-19 in Non-Critically Ill Patients: A Randomized Controlled Trial

(2021) Mahmoud M. A. Abulmeaty et al.   Antioxidants

Inflammatory Response Leads to Neuronal Death in Human Post-Mortem Cerebral Cortex in Patients with COVID-19

(2021) Mahdi Eskandarian Boroujeni et al.   ACS Chemical Neuroscience

COVID-19 disrupts spermatogenesis through the oxidative stress pathway following induction of apoptosis

(2021) Negin Moghimi et al.   APOPTOSIS

The comparison of oxidative markers between Covid-19 patients and healthy subjects

(2021) Fereshteh Mehri et al.   ARCHIVES OF MEDICAL RESEARCH

Effects of antiviral drug therapy on dynamic thiol/disulphide homeostasis and nitric oxide levels in COVID-19 patients

(2021) Ayşe Özlem Mete et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Upregulation of oxidative stress gene markers during SARS-COV-2 viral infection

(2021) Narjes Saheb Sharif-Askari et al.   FREE RADICAL BIOLOGY AND MEDICINE

Thiol levels in mild or moderate COVID‐19 patients: A comparison of variant and classic COVID‐19 cases

(2021) Basri Furkan Dagcioglu et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

Oxidative Stress and Inflammatory Biomarkers for the Prediction of Severity and ICU Admission in Unselected Patients Hospitalized with COVID-19

(2021) Morgane Ducastel et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Thiol level and total oxidant/antioxidant status in patients with COVID-19 infection

(2021) Gökhan Çakırca et al.   IRISH JOURNAL OF MEDICAL SCIENCE

Usefulness of oxidative stress marker evaluation at admission to the intensive care unit in patients with COVID-19

(2021) Hayrettin Daskaya et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Use of Thiols in the Treatment of COVID-19: Current Evidence

(2021) Mario Cazzola et al.   LUNG

Association of Low Molecular Weight Plasma Aminothiols with the Severity of Coronavirus Disease 2019

(2021) Evgeny Vladimirovich Kryukov et al.   Oxidative Medicine and Cellular Longevity

Oxidant and antioxidant balance in patients with COVID‐19

(2021) Kubra Aykac et al.   PEDIATRIC PULMONOLOGY

A pilot study on intravenous N-Acetylcysteine treatment in patients with mild-to-moderate COVID19-associated acute respiratory distress syndrome

(2021) Abbas Taher et al.   Pharmacological Reports

Regulation of the Dimerization and Activity of SARS-CoV-2 Main Protease through Reversible Glutathionylation of Cysteine 300

(2021) David A. Davis et al.   mBio

Interactions of anti-COVID-19 drug candidates with hepatic transporters may cause liver toxicity and affect pharmacokinetics

(2021) Csilla Ambrus et al.   Scientific Reports

Genetics of symptom remission in outpatients with COVID-19

(2021) Marie-Pierre Dubé et al.   Scientific Reports

Characteristics and Developments in Mesenchymal Stem Cell Therapy for COVID-19: An Update

(2021) Lu Sang et al.   Stem Cells International

SARS-CoV-2 Coronavirus Spike Protein-Induced Apoptosis, Inflammatory, and Oxidative Stress Responses in THP-1-Like-Macrophages: Potential Role of Angiotensin-Converting Enzyme Inhibitor (Perindopril)

(2021) Tlili Barhoumi et al.   Frontiers in Immunology

N-acetyl-cysteine reduces the risk for mechanical ventilation and mortality in patients with COVID-19 pneumonia: a two-center retrospective cohort study

(2021) Stelios F. Assimakopoulos et al.   Infectious Diseases

Boswellic acids/Boswellia serrata extract as a potential COVID-19 therapeutic agent in the elderly

(2021) Adel A. Gomaa et al.   INFLAMMOPHARMACOLOGY

SARS-CoV2 infection impairs the metabolism and redox function of cellular glutathione

(2021) Desirée Bartolini et al.   Redox Biology

Clinical Performance of Paraoxonase-1-Related Variables and Novel Markers of Inflammation in Coronavirus Disease-19. A Machine Learning Approach

(2021) Elisabet Rodríguez-Tomàs et al.   Antioxidants

Resveratrol as an Adjunctive Therapy for Excessive Oxidative Stress in Aging COVID-19 Patients

(2021) Min-Tser Liao et al.   Antioxidants

Acute Lung Injury Biomarkers in the Prediction of COVID-19 Severity: Total Thiol, Ferritin and Lactate Dehydrogenase

(2021) Alvaro Martinez Mesa et al.   Antioxidants

Time Course of Redox Biomarkers in COVID-19 Pneumonia: Relation with Inflammatory, Multiorgan Impairment Biomarkers and CT Findings

(2021) Tijana Kosanovic et al.   Antioxidants

The 15-Months Clinical Experience of SARS-CoV-2: A Literature Review of Therapies and Adjuvants

(2021) Alessio Danilo Inchingolo et al.   Antioxidants

N-Acetylcysteine (NAC): Impacts on Human Health

(2021) Micaely Cristina dos Santos Tenório et al.   Antioxidants

Preliminary Findings on the Association of the Lipid Peroxidation Product 4-Hydroxynonenal with the Lethal Outcome of Aggressive COVID-19

(2021) Neven Žarković et al.   Antioxidants

N-Acetylcysteine as Adjuvant Therapy for COVID-19 – A Perspective on the Current State of the Evidence

(2021) Kon Ken Wong et al.   Journal of Inflammation Research

Trans-ethnic genome-wide association study of severe COVID-19

(2021) Peng Wu et al.   Communications Biology

Host gene variability and SARS-CoV-2 infection: A review article

(2021) I. Kaidashev et al.   Heliyon

Mesenchymal stem cell treatment improves outcome of COVID-19 patients via multiple immunomodulatory mechanisms

(2021) Rongjia Zhu et al.   CELL RESEARCH

The COVID-19 pandemic: viral variants and vaccine efficacy

(2021) Marco Ciotti et al.   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

Plasma S-Adenosylmethionine Is Associated with Lung Injury in COVID-19

(2021) Evgeny Vladimirovich Kryukov et al.   DISEASE MARKERS

SARS‐CoV‐2 nucleocapsid protein interacts with immunoregulators and stress granules and phase separates to form liquid droplets

(2021) Syam Prakash Somasekharan et al.   FEBS LETTERS

Review on oxidative stress relation on COVID-19: Biomolecular and bioanalytical approach

(2021) Mehrnaz Ebrahimi et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

SARS-CoV-2 Exacerbates Beta-Amyloid Neurotoxicity, Inflammation and Oxidative Stress in Alzheimer’s Disease Patients

(2021) Luigi Chiricosta et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Total antioxidant capacity as a marker of severity of COVID‐19 infection: Possible prognostic and therapeutic clinical application

(2021) Neda Yaghoubi et al.   JOURNAL OF MEDICAL VIROLOGY

Mitochondrial Dynamics in SARS-COV2 Spike Protein Treated Human Microglia: Implications for Neuro-COVID

(2021) Erin Clough et al.   Journal of Neuroimmune Pharmacology

Molnupiravir for Oral Treatment of Covid-19 in Nonhospitalized Patients

(2021) Angélica Jayk Bernal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Early Remdesivir to Prevent Progression to Severe Covid-19 in Outpatients

(2021) Robert L. Gottlieb et al.   NEW ENGLAND JOURNAL OF MEDICINE

Early Treatment for Covid-19 with SARS-CoV-2 Neutralizing Antibody Sotrovimab

(2021) Anil Gupta et al.   NEW ENGLAND JOURNAL OF MEDICINE

LAMTOR5-AS1 regulates chemotherapy-induced oxidative stress by controlling the expression level and transcriptional activity of NRF2 in osteosarcoma cells

(2021) Youguang Pu et al.   Cell Death & Disease

Investigation of MBL2 and NOS3 functional gene variants in suspected COVID-19 PCR (–) patients

(2021) Sacide Pehlivan et al.   Pathogens and Global Health

Neutrophil-mediated oxidative stress and albumin structural damage predict COVID-19-associated mortality

(2021) Mohamed A Badawy et al.   eLife

Blood Transcriptomes of Anti-SARS-CoV-2 Antibody-Positive Healthy Individuals Who Experienced Asymptomatic Versus Clinical Infection

(2021) Petros P. Sfikakis et al.   Frontiers in Immunology

Lipid peroxidation as a hallmark of severity in COVID-19 patients

(2021) Marta Martín-Fernández et al.   Redox Biology

Oxidative stress transforms 3CLpro into an insoluble and more active form to promote SARS-CoV-2 replication

(2021) Liubing Du et al.   Redox Biology

Therapeutic application of estrogen for COVID-19: Attenuation of SARS-CoV-2 spike protein and IL-6 stimulated, ACE2-dependent NOX2 activation, ROS production and MCP-1 upregulation in endothelial cells

(2021) Ji Youn Youn et al.   Redox Biology

The role of NADPH oxidases in infectious and inflammatory diseases

(2021) Jared P. Taylor et al.   Redox Biology

Genome-wide association study of hospitalized COVID-19 patients in the United Arab Emirates

(2021) Mira Mousa et al.   EBioMedicine

Nebulization of Low-Dose S-Nitrosoglutathione in Diabetic Stroke Enhances Benefits of Reperfusion and Prevents Post-Thrombolysis Hemorrhage

(2021) Syed Kashif Zaidi et al.   Biomolecules

Implications of Vitamins in COVID-19 Prevention and Treatment through Immunomodulatory and Anti-Oxidative Mechanisms

(2021) Juan M. Toledano et al.   Antioxidants

Mild Coronavirus Disease 2019 (COVID-19) Is Marked by Systemic Oxidative Stress: A Pilot Study

(2021) Larissa E. van Eijk et al.   Antioxidants

Mitochondrial and Oxidative Unbalance in Placentas from Mothers with SARS-CoV-2 Infection

(2021) Chiara Mandò et al.   Antioxidants

Severe Glutathione Deficiency, Oxidative Stress and Oxidant Damage in Adults Hospitalized with COVID-19: Implications for GlyNAC (Glycine and N-Acetylcysteine) Supplementation

(2021) Premranjan Kumar et al.   Antioxidants

GSTP1 and GSTM3 Variant Alleles Affect Susceptibility and Severity of COVID-19

(2021) Vesna Coric et al.   Frontiers in Molecular Biosciences

The effect of N-acetyl cysteine consumption on men with abnormal sperm parameters due to positive history of COVID-19 in the last three months

(2021) Bahare Rafiee et al.   Archivio Italiano di Urologia e Andrologia

Prevalence and mortality of COVID-19 are associated with the L55M functional polymorphism of Paraoxonase 1

(2021) Mostafa Saadat   Proceedings of Singapore Healthcare

Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study

(2020) Nanshan Chen et al.   LANCET

Coronavirus Disease 2019 (COVID-19): A Perspective from China

(2020) Zi Yue Zu et al.   RADIOLOGY

COVID‐19Clinical trials: quality matters more than quantity

(2020) Sergio Bonini et al.   ALLERGY

COVID-19 with Different Severities: A Multicenter Study of Clinical Features

(2020) Yun Feng et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Oxidative Stress as Key Player in Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) Infection

(2020) Livan Delgado-Roche et al.   ARCHIVES OF MEDICAL RESEARCH

The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic

(2020)   EUROPEAN JOURNAL OF HUMAN GENETICS

Remdesivir for the Treatment of Covid-19 — Preliminary Report

(2020) John H. Beigel et al.   NEW ENGLAND JOURNAL OF MEDICINE

Strengthening the Immune System and Reducing Inflammation and Oxidative Stress through Diet and Nutrition: Considerations during the COVID-19 Crisis

(2020) Mohammed Iddir et al.   Nutrients

Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China

(2020) Chaomin Wu et al.   JAMA Internal Medicine

Prevalence of Asymptomatic SARS-CoV-2 Infection

(2020) Daniel P. Oran et al.   ANNALS OF INTERNAL MEDICINE

Redox control in the pathophysiology of influenza virus infection

(2020) Ker-Kong Chen et al.   BMC MICROBIOLOGY

COVID-19: a complex multisystem disorder

(2020) C. Michael Roberts et al.   BRITISH JOURNAL OF ANAESTHESIA

Rationale for the use of N -acetylcysteine in both prevention and adjuvant therapy of COVID-19

(2020) Silvio De Flora et al.   FASEB JOURNAL

From SARS to SARS-CoV-2, insights on structure, pathogenicity and immunity aspects of pandemic human coronaviruses

(2020) Nikhil Kirtipal et al.   INFECTION GENETICS AND EVOLUTION

Extrapulmonary complications of COVID‐19: A multisystem disease?

(2020) Kenneth I. Zheng et al.   JOURNAL OF MEDICAL VIROLOGY

Systematic review of the registered clinical trials for coronavirus disease 2019 (COVID-19)

(2020) Rui-fang Zhu et al.   Journal of Translational Medicine

Is Antioxidant Therapy a Useful Complementary Measure for Covid-19 Treatment? An Algorithm for Its Application

(2020) María Elena Soto et al.   Medicina-Lithuania

Genomewide Association Study of Severe Covid-19 with Respiratory Failure

(2020) David Ellinghaus et al.   NEW ENGLAND JOURNAL OF MEDICINE

Covid‐19 and thymoquinone: Connecting the dots

(2020) Ajaz Ahmad et al.   PHYTOTHERAPY RESEARCH

The clinical implication of dynamic neutrophil to lymphocyte ratio and D-dimer in COVID-19: A retrospective study in Suzhou China

(2020) Jianhong Fu et al.   THROMBOSIS RESEARCH

Immune and Metabolic Signatures of COVID-19 Revealed by Transcriptomics Data Reuse

(2020) Luiz G. Gardinassi et al.   Frontiers in Immunology

Current updates on the European and WHO registered clinical trials of coronavirus disease 2019 (COVID-19)

(2020) Henu Kumar Verma et al.   Biomedical Journal

Genetic Polymorphisms Complicate COVID-19 Therapy: Pivotal Role of HO-1 in Cytokine Storm

(2020) Eddie W. Fakhouri et al.   Antioxidants

The Role of Glutathione in Protecting against the Severe Inflammatory Response Triggered by COVID-19

(2020) Francesca Silvagno et al.   Antioxidants

An Antioxidant Enzyme Therapeutic for COVID‐19

(2020) Meng Qin et al.   ADVANCED MATERIALS

Testicular Changes Associated with SARS-CoV-2

(2020) Abdallah Flaifel et al.   ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE

Protective Role of Glutathione against Peroxynitrite-Mediated DNA Damage During Acute Inflammation

(2020) Nabeel Ahmed et al.   CHEMICAL RESEARCH IN TOXICOLOGY

An evidence for correlation between the glutathione S-transferase T1 (GSTT1) polymorphism and outcome of COVID-19

(2020) Mostafa Saadat   CLINICA CHIMICA ACTA

Therapeutic blockade of inflammation in severe COVID-19 infection with intravenous N-acetylcysteine

(2020) Homam Ibrahim et al.   CLINICAL IMMUNOLOGY

Double-blind, randomized, placebo-controlled trial with N-acetylcysteine for treatment of severe acute respiratory syndrome caused by COVID-19

(2020) Julio Cesar Garcia de Alencar et al.   CLINICAL INFECTIOUS DISEASES

Application of methylene blue -vitamin C –N-acetyl cysteine for treatment of critically ill COVID-19 patients, report of a phase-I clinical trial

(2020) Daryoush Hamidi Alamdari et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

SARS-CoV-2 infection pathogenesis is related to oxidative stress as a response to aggression

(2020) Rubens Cecchini et al.   MEDICAL HYPOTHESES

Experience of N-acetylcysteine airway management in the successful treatment of one case of critical condition with COVID-19

(2020) Yan Liu et al.   MEDICINE

Association of glutathione S-transferase M1 and T1 genotypes with asthma

(2020) Xinming Su et al.   MEDICINE

Mitochondria and microbiota dysfunction in COVID-19 pathogenesis

(2020) Jumana Saleh et al.   MITOCHONDRION

A role for quercetin in coronavirus disease 2019 (COVID‐19)

(2020) Giuseppe Derosa et al.   PHYTOTHERAPY RESEARCH

Can Activation of NRF2 Be a Strategy against COVID-19?

(2020) Antonio Cuadrado et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate

(2020) David Olagnier et al.   Nature Communications

Cross talk between oxidative stress and inflammation in alopecia areata

(2020) AI. Mustafa et al.   Journal of Cosmetic Dermatology

Nox2 activation in Covid-19

(2020) Francesco Violi et al.   Redox Biology

Pharmacogenomics of COVID-19 therapies

(2020) Takuto Takahashi et al.   npj Genomic Medicine

Glutathione Supplementation as an Adjunctive Therapy in COVID-19

(2020) Vika Guloyan et al.   Antioxidants

Oxidative Stress and Inflammation in COVID-19-Associated Sepsis: The Potential Role of Anti-Oxidant Therapy in Avoiding Disease Progression

(2020) Jesús Beltrán-García et al.   Antioxidants

SARS-CoV-2 Infection Dysregulates the Metabolomic and Lipidomic Profiles of Serum

(2020) Chiara Bruzzone et al.   iScience

Understanding Selenium and Glutathione as Antiviral Factors in COVID-19: Does the Viral Mpro Protease Target Host Selenoproteins and Glutathione Synthesis?

(2020) Ethan Will Taylor et al.   Frontiers in Nutrition

Does eNOS derived nitric oxide protect the young from severe COVID-19 complications?

(2020) Shou Ping Guan et al.   AGEING RESEARCH REVIEWS

Heme oxygenase-1 modulation: A potential therapeutic target for COVID-19 and associated complications

(2020) Devendra Singh et al.   FREE RADICAL BIOLOGY AND MEDICINE

The potential link between inherited G6PD deficiency, oxidative stress, and vitamin D deficiency and the racial inequities in mortality associated with COVID-19

(2020) Sushil K. Jain et al.   FREE RADICAL BIOLOGY AND MEDICINE

Genetic mechanisms of critical illness in Covid-19

(2020) Erola Pairo-Castineira et al.   NATURE

The Gene Ontology resource: enriching a GOld mine

(2020) et al.   NUCLEIC ACIDS RESEARCH

Ebselen, a new candidate therapeutic against SARS-CoV-2

(2020) C.V. Haritha et al.   International Journal of Surgery

Role of Nrf2 and Its Activators in Respiratory Diseases

(2019) Qinmei Liu et al.   Oxidative Medicine and Cellular Longevity

Intracellular Neutrophil Oxidants: From Laboratory Curiosity to Clinical Reality

(2019) Claes Dahlgren et al.   JOURNAL OF IMMUNOLOGY

Toward understanding the origin and evolution of cellular organisms

(2019) Minoru Kanehisa   PROTEIN SCIENCE

A novel NOX2 inhibitor attenuates human neutrophil oxidative stress and ameliorates inflammatory arthritis in mice

(2019) Fu-Chao Liu et al.   Redox Biology

The reactome pathway knowledgebase

(2019) Bijay Jassal et al.   NUCLEIC ACIDS RESEARCH

A Review of Dietary (Phyto)Nutrients for Glutathione Support

(2019) Deanna M. Minich et al.   Nutrients

Iron homeostasis and oxidative stress: An intimate relationship

(2019) Dimitrios Galaris et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Peroxiredoxin-1 regulates lipid peroxidation in corneal endothelial cells

(2019) Matthew Lovatt et al.   Redox Biology

Myeloperoxidase: Its role for host defense, inflammation, and neutrophil function

(2018) Yasuaki Aratani   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Cathepsin B links oxidative stress to the activation of NLRP3 inflammasome

(2018) Hua Bai et al.   EXPERIMENTAL CELL RESEARCH

Role of glutathione peroxidase 1 in glucose and lipid metabolism-related diseases

(2018) Jia-Qiang Huang et al.   FREE RADICAL BIOLOGY AND MEDICINE

An Improved Inhaled Mucolytic to Treat Airway Muco-Obstructive Diseases

(2018) Camille Ehre et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Redox Biology of Respiratory Viral Infections

(2018) Olga Khomich et al.   Viruses-Basel

The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019

(2018) Annalisa Buniello et al.   NUCLEIC ACIDS RESEARCH

Efficacy of nebulized acetylcysteine for relieving symptoms and reducing usage of expectorants in patients with radiation pneumonitis

(2018) Dong-Woo Han et al.   Thoracic Cancer

Neutrophils to the ROScue: Mechanisms of NADPH Oxidase Activation and Bacterial Resistance

(2017) Giang T. Nguyen et al.   Frontiers in Cellular and Infection Microbiology

Translational Significance of Heme Oxygenase in Obesity and Metabolic Syndrome

(2016) Nader G. Abraham et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

RORα Decreases Oxidative Stress Through the Induction of SOD2 and GPx1 Expression and Thereby Protects Against Nonalcoholic Steatohepatitis in Mice

(2014) Yong-Hyun Han et al.   ANTIOXIDANTS & REDOX SIGNALING

ROS Function in Redox Signaling and Oxidative Stress

(2014) Michael Schieber et al.   CURRENT BIOLOGY

N-acetyl-l-cystine (NAC) protects against H9N2 swine influenza virus-induced acute lung injury

(2014) Rui-Hua Zhang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

ROS upregulation during the early phase of retroviral infection plays an important role in viral establishment in the host cell

(2013) S. J. Kim et al.   JOURNAL OF GENERAL VIROLOGY

Glutathione S-transferase polymorphisms, asthma susceptibility and confounding variables: a meta-analysis

(2013) Sara Piacentini et al.   MOLECULAR BIOLOGY REPORTS

N-Acetylcysteine mucolysis in the management of chronic obstructive pulmonary disease

(2012) Anna M. Sadowska   Therapeutic Advances in Respiratory Disease

Rhinovirus-Induced Barrier Dysfunction in Polarized Airway Epithelial Cells Is Mediated by NADPH Oxidase 1

(2011) A. T. Comstock et al.   JOURNAL OF VIROLOGY

Role of MGST1 in reactive intermediate-induced injury

(2011) Courtney S Schaffert   WORLD JOURNAL OF GASTROENTEROLOGY

Association Between Heme Oxygenase-1 Gene Promoter Polymorphisms and Type 2 Diabetes Mellitus: A HuGE Review and Meta-Analysis

(2010) Wei Bao et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Human catalase: looking for complete identity

(2010) Madhur M. Goyal et al.   Protein & Cell

Protective actions of sex steroid hormones in Alzheimer’s disease

(2009) Christian J. Pike et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Measurement of superoxide dismutase, catalase and glutathione peroxidase in cultured cells and tissue

(2009) Christine J Weydert et al.   Nature Protocols

Expression of a Mutant Form of the Ferritin Light Chain Gene Induces Neurodegeneration and Iron Overload in Transgenic Mice

(2008) R. Vidal et al.   JOURNAL OF NEUROSCIENCE

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH