Redox control in the pathophysiology of influenza virus infection

Targeting evolutionary conserved oxidative stress and immunometabolic pathways for the treatment of respiratory infectious diseases

(2020) Jonathan Erlich et al.   ANTIOXIDANTS & REDOX SIGNALING

TRPM2, linking oxidative stress and Ca2+ permeation to NLRP3 inflammasome activation

(2020) Longfei Wang et al.   CURRENT OPINION IN IMMUNOLOGY

Berberine suppresses influenza virus-triggered NLRP3 inflammasome activation in macrophages by inducing mitophagy and decreasing mitochondrial ROS

(2020) Hui Liu et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Reactive oxygen species (ROS) as pleiotropic physiological signalling agents

(2020) Helmut Sies et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The dual role of innate immunity during influenza

(2019) Carmelo Biondo et al.   Biomedical Journal

Influenza Virus Infections and Cellular Kinases

(2019) Robert Meineke et al.   Viruses-Basel

Novel endosomal NOX2 oxidase inhibitor ameliorates pandemic influenza A virus‐induced lung inflammation in mice

(2019) Eunice E. To et al.   RESPIROLOGY

Inducible lung epithelial resistance requires multisource reactive oxygen species generation to protect against bacterial infections

(2019) Hayden H. Ware et al.   PLoS One

Singlet molecular oxygen regulates vascular tone and blood pressure in inflammation

(2019) Christopher P. Stanley et al.   NATURE

Viral Factors Important for Efficient Replication of Influenza A Viruses in Cells of the Central Nervous System

(2019) Jurre Y. Siegers et al.   JOURNAL OF VIROLOGY

Efficacy of laninamivir octanoate in mice with advanced inflammation stage caused by infection of highly lethal influenza virus

(2019) Takanori Tomozawa et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

Endoplasmic reticulum-associated degradation potentiates the infectivity of influenza A virus by regulating the host redox state

(2019) Kwang Il Jung et al.   FREE RADICAL BIOLOGY AND MEDICINE

Utilization of Dianthus superbus L and its bioactive compounds for antioxidant, anti-influenza and toxicological effects

(2019) Doo Hwan Kim et al.   FOOD AND CHEMICAL TOXICOLOGY

Identification of NMS-873, an allosteric and specific p97 inhibitor, as a broad antiviral against both influenza A and B viruses

(2019) Jiantao Zhang et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Atorvastatin restricts the ability of influenza virus to generate lipid droplets and severely suppresses the replication of the virus

(2019) Donna Episcopio et al.   FASEB JOURNAL

Baloxavir marboxil: the new influenza drug on the market

(2019) Ryan O’Hanlon et al.   Current Opinion in Virology

Lung epithelial protein disulfide isomerase A3 (PDIA3) plays an important role in influenza infection, inflammation, and airway mechanics

(2019) Nicolas Chamberlain et al.   Redox Biology

Mitochondrial Reactive Oxygen Species Contribute to Pathological Inflammation During Influenza A Virus Infection in Mice

(2019) Eunice E. To et al.   ANTIOXIDANTS & REDOX SIGNALING

Single-walled Carbon Nanotubes Repress Viral-Induced Defense Pathways through Oxidative Stress

(2019) Hao Chen et al.   Nanotoxicology

The Role of Polyphenol (Flavonoids) Compounds in the Treatment of Cancer Cells

(2019) Abu Hazafa et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

A novel I117T substitution in neuraminidase of highly pathogenic avian influenza H5N1 virus conferring reduced susceptibility to oseltamivir and zanamivir

(2019) Sadhana S. Kode et al.   VETERINARY MICROBIOLOGY

Targeting the proviral host kinase, FAK, limits influenza a virus pathogenesis and NFkB-regulated pro-inflammatory responses

(2019) Silke Bergmann et al.   VIROLOGY

The Role of Innate Leukocytes during Influenza Virus Infection

(2019) Prem P. Lamichhane et al.   Journal of Immunology Research

Probing the effect of quercetin 3-glucoside from Dianthus superbus L against influenza virus infection- In vitro and in silico biochemical and toxicological screening

(2019) Shivraj Hariram Nile et al.   FOOD AND CHEMICAL TOXICOLOGY

Neuroprotection in Oxidative Stress-Related Neurodegenerative Diseases: Role of Endocannabinoid System Modulation

(2018) Janos Paloczi et al.   ANTIOXIDANTS & REDOX SIGNALING

Triple combination of FDA-approved drugs including flufenamic acid, clarithromycin and zanamivir improves survival of severe influenza in mice

(2018) Andrew C. Y. Lee et al.   ARCHIVES OF VIROLOGY

Clarithromycin suppresses induction of monocyte chemoattractant protein-1 and matrix metalloproteinase-9 and improves pathological changes in the lungs and heart of mice infected with influenza A virus

(2018) Etsuhisa Takahashi et al.   COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES

Baloxavir: First Global Approval

(2018) Young-A Heo   DRUGS

Inhibition of curcumin on influenza A virus infection and influenzal pneumonia via oxidative stress, TLR2/4, p38/JNK MAPK and NF-κB pathways

(2018) Jianping Dai et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Oxymatrine Inhibits Influenza A Virus Replication and Inflammation via TLR4, p38 MAPK and NF-κB Pathways

(2018) Jian-Ping Dai et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Bax Inhibitor-1 Acts as an Anti-Influenza Factor by Inhibiting ROS Mediated Cell Death and Augmenting Heme-Oxygenase 1 Expression in Influenza Virus Infected Cells

(2018) Mohammed Hossain et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Inhibition of H1N1 influenza virus-induced apoptosis by functionalized selenium nanoparticles with amantadine through ROS-mediated AKT signaling pathways

(2018) Yinghua Li et al.   International Journal of Nanomedicine

Micelle-templated, poly(lactic-co-glycolic acid) nanoparticles for hydrophobic drug delivery

(2018) Gauri Nabar et al.   International Journal of Nanomedicine

Synergic effect of curcumin and its structural analogue (Monoacetylcurcumin) on anti-influenza virus infection

(2018) Sarah M. Richart et al.   JOURNAL OF FOOD AND DRUG ANALYSIS

Down-regulation of cellular protein heme oxygenase-1 inhibits proliferation of avian influenza virus H9N2 in chicken oviduct epithelial cells

(2018) Xuefeng Qi et al.   JOURNAL OF GENERAL VIROLOGY

NS1 Protein of 2009 Pandemic Influenza A Virus Inhibits Porcine NLRP3 Inflammasome-Mediated Interleukin-1 Beta Production by Suppressing ASC Ubiquitination

(2018) Hong-Su Park et al.   JOURNAL OF VIROLOGY

Inducible Lung Epithelial Resistance Requires Multisource Reactive Oxygen Species Generation To Protect against Viral Infections

(2018) Carson T. Kirkpatrick et al.   mBio

Aryl hydrocarbon receptor signaling modulates antiviral immune responses: ligand metabolism rather than chemical source is the stronger predictor of outcome

(2018) Lisbeth A. Boule et al.   Scientific Reports

Prion protein protects mice from lethal infection with influenza A viruses

(2018) Junji Chida et al.   PLoS Pathogens

Peramivir: A Review in Uncomplicated Influenza

(2018) Lesley J. Scott   DRUGS

Restriction of H1N1 influenza virus infection by selenium nanoparticles loaded with ribavirin via resisting caspase-3 apoptotic pathway

(2018) Zhengfang Lin et al.   International Journal of Nanomedicine

A Small-Molecule Compound Has Anti-influenza A Virus Activity by Acting as a ‘‘PB2 Inhibitor”

(2018) Teng Liu et al.   MOLECULAR PHARMACEUTICS

Inhibition of autophagy and chemokine induction by sphingosine 1-phosphate receptor 1 through NF-κB signaling in human pulmonary endothelial cells infected with influenza A viruses

(2018) Lan Wang et al.   PLoS One

Swine Influenza Virus Induces RIPK1/DRP1-Mediated Interleukin-1 Beta Production

(2018) Hong-Su Park et al.   Viruses-Basel

Redox Biology of Respiratory Viral Infections

(2018) Olga Khomich et al.   Viruses-Basel

The induction and consequences of Influenza A virus-induced cell death

(2018) Georgia K. Atkin-Smith et al.   Cell Death & Disease

Epigenetic control of influenza virus: role of H3K79 methylation in interferon-induced antiviral response

(2018) Laura Marcos-Villar et al.   Scientific Reports

Potential application of cell reprogramming techniques for cancer research

(2018) Shigeo Saito et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Salinomycin Inhibits Influenza Virus Infection by Disrupting Endosomal Acidification and Viral Matrix Protein 2 Function

(2018) Yejin Jang et al.   JOURNAL OF VIROLOGY

Environmental cues received during development shape dendritic cell responses later in life

(2018) Jessica L. Meyers et al.   PLoS One

The mechanism of resistance to favipiravir in influenza

(2018) Daniel H. Goldhill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure–Property Relationship Studies of Influenza A Virus AM2-S31N Proton Channel Blockers

(2018) Yanmei Hu et al.   ACS Medicinal Chemistry Letters

Nucleocytoplasmic shuttling of the human parainfluenza virus type 2 phosphoprotein

(2018) Junpei Ohtsuka et al.   VIROLOGY

Evolution and Virulence of Influenza A Virus Protein PB1-F2

(2017) Ram Kamal et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Transforming growth factor β1 (TGFβ1)-induced CD44V6-NOX4 signaling in pathogenesis of idiopathic pulmonary fibrosis

(2017) Shibnath Ghatak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aurantiamide acetate from baphicacanthus cusia root exhibits anti-inflammatory and anti-viral effects via inhibition of the NF-κB signaling pathway in Influenza A virus-infected cells

(2017) Beixian Zhou et al.   JOURNAL OF ETHNOPHARMACOLOGY

Emodin Inhibition of Influenza A Virus Replication and Influenza Viral Pneumonia via the Nrf2, TLR4, p38/JNK and NF-kappaB Pathways

(2017) Jian-Ping Dai et al.   MOLECULES

The Nrf2-ARE signaling pathway: An update on its regulation and possible role in cancer prevention and treatment

(2017) Violetta Krajka-Kuźniak et al.   Pharmacological Reports

P2Y6 receptors are involved in mediating the effect of inactivated avian influenza virus H5N1 on IL-6 & CXCL8 mRNA expression in respiratory epithelium

(2017) Nawiya Huipao et al.   PLoS One

Reactive Oxygen Species-Regulating Polymersome as an Antiviral Agent against Influenza Virus

(2017) Hyun-Ouk Kim et al.   Small

Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy

(2017) Eunice E. To et al.   Nature Communications

A CRISPR Activation Screen Identifies a Pan-avian Influenza Virus Inhibitory Host Factor

(2017) Brook E. Heaton et al.   Cell Reports

Sphingosine 1-phosphate receptor 1 (S1PR1) agonist CYM5442 inhibits expression of intracellular adhesion molecule 1 (ICAM1) in endothelial cells infected with influenza A viruses

(2017) Hao Jiang et al.   PLoS One

Antiviral activity of chlorogenic acid against influenza A (H1N1/H3N2) virus and its inhibition of neuraminidase

(2017) Yue Ding et al.   Scientific Reports

Duox2 is required for the transcription of pattern recognition receptors in acute viral lung infection: An interferon-independent regulatory mechanism

(2016) Seung-No Hong et al.   ANTIVIRAL RESEARCH

Crosstalk of mitochondria with NADPH oxidase via reactive oxygen and nitrogen species signalling and its role for vascular function

(2016) Andreas Daiber et al.   BRITISH JOURNAL OF PHARMACOLOGY

Design, synthesis and biological evaluation of novel l-ascorbic acid-conjugated pentacyclic triterpene derivatives as potential influenza virus entry inhibitors

(2016) Han Wang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Regulation of kynurenine biosynthesis during influenza virus infection

(2016) Lana Gaelings et al.   FEBS Journal

PB1-F2 Peptide Derived from Avian Influenza A Virus H7N9 Induces Inflammation via Activation of the NLRP3 Inflammasome

(2016) Anita Pinar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The NS1 protein of avian influenza virus H9N2 induces oxidative-stress-mediated chicken oviduct epithelial cells apoptosis

(2016) Xuefeng Qi et al.   JOURNAL OF GENERAL VIROLOGY

Polymerase Acidic Protein–Basic Protein 1 (PA–PB1) Protein–Protein Interaction as a Target for Next-Generation Anti-influenza Therapeutics

(2016) Serena Massari et al.   JOURNAL OF MEDICINAL CHEMISTRY

Red ginseng and vitamin C increase immune cell activity and decrease lung inflammation induced by influenza A virus/H1N1 infection

(2016) Hyemin Kim et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

The Influenza Virus Polymerase Complex: An Update on Its Structure, Functions, and Significance for Antiviral Drug Design

(2016) Annelies Stevaert et al.   MEDICINAL RESEARCH REVIEWS

Constitutive aryl hydrocarbon receptor signaling constrains type I interferon–mediated antiviral innate defense

(2016) Taisho Yamada et al.   NATURE IMMUNOLOGY

The Host Cell Receptors for Measles Virus and Their Interaction with the Viral Hemagglutinin (H) Protein

(2016) Liang-Tzung Lin et al.   Viruses-Basel

The Influenza Virus H5N1 Infection Can Induce ROS Production for Viral Replication and Host Cell Death in A549 Cells Modulated by Human Cu/Zn Superoxide Dismutase (SOD1) Overexpression

(2016) Xian Lin et al.   Viruses-Basel

Stabilization and Improvement of a Promising Influenza Antiviral: Making a PAIN PAINless

(2016) Aleksandar Antanasijevic et al.   ACS Infectious Diseases

NADPH Oxidase 1 Is Associated with Altered Host Survival and T Cell Phenotypes after Influenza A Virus Infection in Mice

(2016) Amelia R. Hofstetter et al.   PLoS One

The Induction of Pattern-Recognition Receptor Expression against Influenza A Virus through Duox2-Derived Reactive Oxygen Species in Nasal Mucosa

(2015) Hyun Jik Kim et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Influenza A virus PB1-F2 is involved in regulation of cellular redox state in alveolar epithelial cells

(2015) Nary Shin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The cytokine storm of severe influenza and development of immunomodulatory therapy

(2015) Qiang Liu et al.   Cellular & Molecular Immunology

Influenza infection induces host DNA damage and dynamic DNA damage responses during tissue regeneration

(2015) Na Li et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Influenza virus-induced lung injury: pathogenesis and implications for treatment

(2015) Susanne Herold et al.   EUROPEAN RESPIRATORY JOURNAL

Bakuchiol Is a Phenolic Isoprenoid with Novel Enantiomer-selective Anti-influenza A Virus Activity Involving Nrf2 Activation

(2015) Masaki Shoji et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Highly Pathogenic H5N1 and Novel H7N9 Influenza A Viruses Induce More Profound Proteomic Host Responses than Seasonal and Pandemic H1N1 Strains

(2015) Philippe François Simon et al.   JOURNAL OF PROTEOME RESEARCH

Emerging roles of hypoxia-inducible factors and reactive oxygen species in cancer and pluripotent stem cells

(2015) Shigeo Saito et al.   KAOHSIUNG JOURNAL OF MEDICAL SCIENCES

Redox Proteomics of the Inflammatory Secretome Identifies a Common Set of Redoxins and Other Glutathionylated Proteins Released in Inflammation, Influenza Virus Infection and Oxidative Stress

(2015) Paola Checconi et al.   PLoS One

Differential neutrophil activation in viral infections: Enhanced TLR-7/8-mediated CXCL8 release in asthma

(2015) Francesca S.M. Tang et al.   RESPIROLOGY

PRR-signaling pathways: Learning from microbial tactics

(2015) Gernot Sellge et al.   SEMINARS IN IMMUNOLOGY

Insights into Human Astrocyte Response to H5N1 Infection by Microarray Analysis

(2015) Xian Lin et al.   Viruses-Basel

Quercetin as an Antiviral Agent Inhibits Influenza A Virus (IAV) Entry

(2015) Wenjiao Wu et al.   Viruses-Basel

Plasminogen Activator Inhibitor-1 in Cigarette Smoke Exposure and Influenza A Virus Infection-Induced Lung Injury

(2015) Yashodhar P. Bhandary et al.   PLoS One

Does Influenza A Infection Increase Oxidative Damage?

(2014) Mary P.E. Ng et al.   ANTIOXIDANTS & REDOX SIGNALING

Alteration of copper–zinc superoxide dismutase 1 expression by influenza A virus is correlated with virus replication

(2014) Chul-Woong Pyo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

NADPH oxidases: an overview from structure to innate immunity-associated pathologies

(2014) Arvind Panday et al.   Cellular & Molecular Immunology

Influenza virus replication in lung epithelial cells depends on redox-sensitive pathways activated by NOX4-derived ROS

(2014) Donatella Amatore et al.   CELLULAR MICROBIOLOGY

Intracellular Redox State as Target for Anti-Influenza Therapy: Are Antioxidants Always Effective?

(2014) Rossella Sgarbanti et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

N-acetyl-l-cystine (NAC) protects against H9N2 swine influenza virus-induced acute lung injury

(2014) Rui-Hua Zhang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Inhibition of Reactive Oxygen Species Production Ameliorates Inflammation Induced by Influenza A Viruses via Upregulation of SOCS1 and SOCS3

(2014) Siying Ye et al.   JOURNAL OF VIROLOGY

Single-walled carbon nanotubes increase pandemic influenza A H1N1 virus infectivity of lung epithelial cells

(2014) Pallab Sanpui et al.   Particle and Fibre Toxicology

Proteomics study ofN-acetylcysteine response in H1N1-infected cells by using mass spectrometry

(2014) Hanzhi Wu et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Influenza A virus protein PB1-F2 translocates into mitochondria via Tom40 channels and impairs innate immunity

(2014) Takuma Yoshizumi et al.   Nature Communications

Toward a Universal Influenza Virus Vaccine: Prospects and Challenges

(2013) Natalie Pica et al.   Annual Review of Medicine

Mucosal Reactive Oxygen Species Are Required for Antiviral Response: Role of Duox in Influenza A Virus Infection

(2013) Monika Strengert et al.   ANTIOXIDANTS & REDOX SIGNALING

Favipiravir (T-705), a novel viral RNA polymerase inhibitor

(2013) Yousuke Furuta et al.   ANTIVIRAL RESEARCH

Development of cellular signaling pathway inhibitors as new antivirals against influenza

(2013) Oliver Planz   ANTIVIRAL RESEARCH

The aryl hydrocarbon receptor interacts with nuclear factor erythroid 2-related factor 2 to mediate induction of NAD(P)H:quinoneoxidoreductase 1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin

(2013) Liping Wang et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

How do nutritional antioxidants really work: Nucleophilic tone and para-hormesis versus free radical scavenging in vivo

(2013) Henry J. Forman et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxygen free radical involvement in acute lung injury induced by H5N1 virus in mice

(2013) Guimei He et al.   Influenza and Other Respiratory Viruses

Role of human Toll-like receptors in naturally occurring influenza A infections

(2013) Nelson Lee et al.   Influenza and Other Respiratory Viruses

The TLR4 antagonist Eritoran protects mice from lethal influenza infection

(2013) Kari Ann Shirey et al.   NATURE

Nox1 Oxidase Suppresses Influenza A Virus-Induced Lung Inflammation and Oxidative Stress

(2013) Stavros Selemidis et al.   PLoS One

Inhibition of Influenza H7 Hemagglutinin-Mediated Entry

(2013) Aleksandar Antanasijevic et al.   PLoS One

Mitochondrial protein mitofusin 2 is required for NLRP3 inflammasome activation after RNA virus infection

(2013) T. Ichinohe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential Consequences of Two Distinct AhR Ligands on Innate and Adaptive Immune Responses to Influenza A Virus

(2013) Jennifer L. H. Wheeler et al.   TOXICOLOGICAL SCIENCES

Influenza A virus induction of oxidative stress and MMP-9 is associated with severe lung pathology in a mouse model

(2013) Yu-Hsiang Lee et al.   VIRUS RESEARCH

Vitamin C Is an Essential Factor on the Anti-viral Immune Responses through the Production of Interferon-α/β at the Initial Stage of Influenza A Virus (H3N2) Infection

(2013) Yejin Kim et al.   Immune Network

Amelioration of influenza virus-induced reactive oxygen species formation by epigallocatechin gallate derived from green tea

(2012) Jia-xin Ling et al.   ACTA PHARMACOLOGICA SINICA

Glutathione Peroxidase-1 Reduces Influenza A Virus–Induced Lung Inflammation

(2012) Selcuk Yatmaz et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Redox Signaling by 8-Nitro-cyclic Guanosine Monophosphate: Nitric Oxide- and Reactive Oxygen Species-Derived Electrophilic Messenger

(2012) Shigemoto Fujii et al.   ANTIOXIDANTS & REDOX SIGNALING

Chlorogenic acid inhibits LPS-induced microglial activation and improves survival of dopaminergic neurons

(2012) Wenjuan Shen et al.   BRAIN RESEARCH BULLETIN

Novel Cellular Targets of AhR Underlie Alterations in Neutrophilic Inflammation and Inducible Nitric Oxide Synthase Expression during Influenza Virus Infection

(2012) J. L. H. Wheeler et al.   JOURNAL OF IMMUNOLOGY

Antivirals Targeting Influenza A Virus

(2012) Kalyan Das   JOURNAL OF MEDICINAL CHEMISTRY

Major Shifts in the Spatio-Temporal Distribution of Lung Antioxidant Enzymes during Influenza Pneumonia

(2012) Yoshiyuki Yamada et al.   PLoS One

Nrf2 protects human alveolar epithelial cells against injury induced by influenza A virus

(2012) Beata Kosmider et al.   RESPIRATORY RESEARCH

Matrix Metalloprotease 9 Mediates Neutrophil Migration into the Airways in Response to Influenza Virus-Induced Toll-Like Receptor Signaling

(2012) Linda M. Bradley et al.   PLoS Pathogens

Influenza Induces Endoplasmic Reticulum Stress, Caspase-12–Dependent Apoptosis, and c-Jun N-Terminal Kinase–Mediated Transforming Growth Factor–β Release in Lung Epithelial Cells

(2011) Elle C. Roberson et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Redox Regulation of the Influenza Hemagglutinin Maturation Process: A New Cell-Mediated Strategy for Anti-Influenza Therapy

(2011) Rossella Sgarbanti et al.   ANTIOXIDANTS & REDOX SIGNALING

Nrf2 expression modifies influenza A entry and replication in nasal epithelial cells

(2011) Matthew J. Kesic et al.   FREE RADICAL BIOLOGY AND MEDICINE

Antihypertensive effects and mechanisms of chlorogenic acids

(2011) Youyou Zhao et al.   HYPERTENSION RESEARCH

Role of Nrf2 in Host Defense against Influenza Virus in Cigarette Smoke-Exposed Mice

(2011) Y. Yageta et al.   JOURNAL OF VIROLOGY

Antioxidant Therapy as a Potential Approach to Severe Influenza-Associated Complications

(2011) Noboru Uchide et al.   MOLECULES

Increased Inducible Nitric Oxide Synthase Expression in Organs Is Associated with a Higher Severity of H5N1 Influenza Virus Infection

(2011) Simon Burggraaf et al.   PLoS One

Intracellular ROS Protection Efficiency and Free Radical-Scavenging Activity of Curcumin

(2011) Abolfazl Barzegar et al.   PLoS One

Suppressing production of reactive oxygen species (ROS) for influenza A virus therapy

(2011) Ross Vlahos et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Induction of Inflammatory Cytokines and Toll-like Receptors in Human Normal Respiratory Epithelial Cells Infected with Seasonal H1N1, 2009 Pandemic H1N1, Seasonal H3N2, and Highly Pathogenic H5N1 Influenza Virus

(2011) Byung Min Song et al.   VIRAL IMMUNOLOGY

Lung histopathological findings in fatal pandemic influenza A (H1N1)

(2011) N. Nin et al.   Medicina Intensiva

Temporal Dynamics of Host Molecular Responses Differentiate Symptomatic and Asymptomatic Influenza A Infection

(2011) Yongsheng Huang et al.   PLoS Genetics

Inhibition of Nox2 Oxidase Activity Ameliorates Influenza A Virus-Induced Lung Inflammation

(2011) Ross Vlahos et al.   PLoS Pathogens

Nox4 NADPH oxidase-derived reactive oxygen species, via endogenous carbon monoxide, promote survival of brain endothelial cells during TNF-α-induced apoptosis

(2010) Shyamali Basuroy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Indoleamine 2,3-Dioxygenase

(2010) Hatem Soliman et al.   CANCER JOURNAL

Apoptosis and Proinflammatory Cytokine Responses of Primary Mouse Microglia and Astrocytes Induced by Human H1N1 and Avian H5N1 Influenza Viruses

(2010) Gefei Wang et al.   Cellular & Molecular Immunology

Toll-Like Receptor 4-Mediated Activation of p38 Mitogen-Activated Protein Kinase Is a Determinant of Respiratory Virus Entry and Tropism

(2010) D. Marchant et al.   JOURNAL OF VIROLOGY

Influenza caused epidemic encephalitis (encephalitis lethargica): The circumstantial evidence and a challenge to the nonbelievers

(2010) C.P. Maurizi   MEDICAL HYPOTHESES

Avian influenza H5N1 virus induces cytopathy and proinflammatory cytokine responses in human astrocytic and neuronal cell lines

(2010) Y.P. Ng et al.   NEUROSCIENCE

Oligonol a low molecular weight polyphenol of lychee fruit extract inhibits proliferation of influenza virus by blocking reactive oxygen species-dependent ERK phosphorylation

(2010) Leila Gangehei et al.   PHYTOMEDICINE

Aryl Hydrocarbon Receptor Activation Reduces Dendritic Cell Function during Influenza Virus Infection

(2010) Guang-Bi Jin et al.   TOXICOLOGICAL SCIENCES

Potential anticancer application of polyamine oxidation products formed by amine oxidase: a new therapeutic approach

(2009) E. Agostinelli et al.   AMINO ACIDS

N-acetyl-l-cysteine (NAC) inhibits virus replication and expression of pro-inflammatory molecules in A549 cells infected with highly pathogenic H5N1 influenza A virus

(2009) Janina Geiler et al.   BIOCHEMICAL PHARMACOLOGY

Inhibitory effects of quercetin 3-rhamnoside on influenza A virus replication

(2009) Hwa Jung Choi et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Bcl-2 Expression and p38MAPK Activity in Cells Infected with Influenza A Virus

(2009) Lucia Nencioni et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Practical strategies for targeting NF-kappaB and NADPH oxidase may improve survival during lethal influenza epidemics

(2009) Mark F. McCarty et al.   MEDICAL HYPOTHESES

Introducing the “TCDD-Inducible AhR-Nrf2 Gene Battery”

(2009) Ronnie L. Yeager et al.   TOXICOLOGICAL SCIENCES

Role of Nrf1 in antioxidant response element-mediated gene expression and beyond

(2009) Madhurima Biswas et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The Pathology of Influenza Virus Infections

(2008) Jeffery K. Taubenberger et al.   Annual Review of Pathology-Mechanisms of Disease

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

The aryl hydrocarbon receptor is a modulator of anti-viral immunity

(2008) Jennifer L. Head et al.   BIOCHEMICAL PHARMACOLOGY

Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury

(2008) Yumiko Imai et al.   CELL

The proapoptotic influenza A virus protein PB1-F2 regulates viral polymerase activity by interaction with the PB1 protein

(2008) Igor Mazur et al.   CELLULAR MICROBIOLOGY

Thiol chemistry and specificity in redox signaling

(2008) Christine C. Winterbourn et al.   FREE RADICAL BIOLOGY AND MEDICINE

(+)-Vitisin A Inhibits Influenza A Virus-Induced RANTES Production in A549 Alveolar Epithelial Cells through Interference with Akt and STAT1 Phosphorylation

(2008) Yu-Ling Huang et al.   PLANTA MEDICA

Pathology of human influenza revisited

(2008) Thijs Kuiken et al.   VACCINE

Influenza-associated central nervous system dysfunction: A literature review

(2008) Stephen Toovey   Travel Medicine and Infectious Disease