Inflammatory Response Leads to Neuronal Death in Human Post-Mortem Cerebral Cortex in Patients with COVID-19

Evidence of the COVID-19 Virus Targeting the CNS: Tissue Distribution, Host–Virus Interaction, and Proposed Neurotropic Mechanisms

(2020) Abdul Mannan Baig et al.   ACS Chemical Neuroscience

Neuropathology of COVID-19: a spectrum of vascular and acute disseminated encephalomyelitis (ADEM)-like pathology

(2020) R. Ross Reichard et al.   ACTA NEUROPATHOLOGICA

Cytokine storm in COVID-19: pathogenesis and overview of anti-inflammatory agents used in treatment

(2020) Mehmet Soy et al.   CLINICAL RHEUMATOLOGY

Pharmacological perspective: glycyrrhizin may be an efficacious therapeutic agent for COVID-19

(2020) Pan Luo et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

An anti-oxidative therapy for ameliorating cardiac injuries of critically ill COVID-19-infected patients

(2020) Jing-Zhang Wang et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Tramadol: a Potential Neurotoxic Agent Affecting Prefrontal Cortices in Adult Male Rats and PC-12 Cell Line

(2020) Fakhroddin Aghajanpour et al.   NEUROTOXICITY RESEARCH

Cell entry mechanisms of SARS-CoV-2

(2020) Jian Shang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

COVID-19: The Inflammation Link and the Role of Nutrition in Potential Mitigation

(2020) Ioannis Zabetakis et al.   Nutrients

Endogenous Deficiency of Glutathione as the Most Likely Cause of Serious Manifestations and Death in COVID-19 Patients

(2020) Alexey Polonikov   ACS Infectious Diseases

The protein expression profile of ACE2 in human tissues

(2020) Feria Hikmet et al.   Molecular Systems Biology

Extrapulmonary manifestations of COVID-19

(2020) Aakriti Gupta et al.   NATURE MEDICINE

Neurochemical evidence of astrocytic and neuronal injury commonly found in COVID-19

(2020) Nelly Kanberg et al.   NEUROLOGY

The Role of Glutathione in Protecting against the Severe Inflammatory Response Triggered by COVID-19

(2020) Francesca Silvagno et al.   Antioxidants

Neurological manifestations of COVID-19: available evidences and a new paradigm

(2020) Fatima Khatoon et al.   JOURNAL OF NEUROVIROLOGY

Paracetamol-Induced Glutathione Consumption: Is There a Link With Severe COVID-19 Illness?

(2020) Piero Sestili et al.   Frontiers in Pharmacology

The S1 protein of SARS-CoV-2 crosses the blood–brain barrier in mice

(2020) Elizabeth M. Rhea et al.   NATURE NEUROSCIENCE

Microvascular Injury in the Brains of Patients with Covid-19

(2020) Myoung-Hwa Lee et al.   NEW ENGLAND JOURNAL OF MEDICINE

Detrimental Effects of HMGB-1 Require Microglial-Astroglial Interaction: Implications for the Status Epilepticus -Induced Neuroinflammation

(2019) Gerardo Rosciszewski et al.   Frontiers in Cellular Neuroscience

The Role of Microglia and Astrocytes in Huntington’s Disease

(2019) Thulani H. Palpagama et al.   Frontiers in Molecular Neuroscience

Alpha/Beta Interferon (IFN-α/β) Signaling in Astrocytes Mediates Protection against Viral Encephalomyelitis and Regulates IFN-γ-Dependent Responses

(2018) Mihyun Hwang et al.   JOURNAL OF VIROLOGY

Regulation of microglial process elongation, a featured characteristic of microglial plasticity

(2018) Rongrong Yang et al.   PHARMACOLOGICAL RESEARCH

Reactive Astrocytes: Production, Function, and Therapeutic Potential

(2017) Shane A. Liddelow et al.   IMMUNITY

Toll-Like Receptor 4 (TLR4) and Triggering Receptor Expressed on Myeloid Cells-2 (TREM-2) Activation Balance Astrocyte Polarization into a Proinflammatory Phenotype

(2017) Gerardo Rosciszewski et al.   MOLECULAR NEUROBIOLOGY

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

Liposomal Glutathione Supplementation Restores TH1 Cytokine Response toMycobacterium tuberculosisInfection in HIV-Infected Individuals

(2015) Judy Ly et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Viral Infection of the Central Nervous System and Neuroinflammation Precede Blood-Brain Barrier Disruption during Japanese Encephalitis Virus Infection

(2015) Fang Li et al.   JOURNAL OF VIROLOGY

Immune Surveillance of the CNS following Infection and Injury

(2015) Matthew V. Russo et al.   TRENDS IN IMMUNOLOGY

Viral diseases of the central nervous system

(2015) Phillip A Swanson et al.   Current Opinion in Virology

Influenza virus replication in lung epithelial cells depends on redox-sensitive pathways activated by NOX4-derived ROS

(2014) Donatella Amatore et al.   CELLULAR MICROBIOLOGY

Influenza Infection Suppresses NADPH Oxidase-Dependent Phagocytic Bacterial Clearance and Enhances Susceptibility to Secondary Methicillin-Resistant Staphylococcus aureus Infection

(2014) K. Sun et al.   JOURNAL OF IMMUNOLOGY

Quantitative assessment of microglial morphology and density reveals remarkable consistency in the distribution and morphology of cells within the healthy prefrontal cortex of the rat

(2014) Ratchaniporn Kongsui et al.   Journal of Neuroinflammation

Bone marrow mesenchymal stem cell transplantation in patients with multiple sclerosis: A pilot study

(2010) Bassem Yamout et al.   JOURNAL OF NEUROIMMUNOLOGY

Angiotensin-converting enzyme 2 in the brain: properties and future directions

(2008) Huijing Xia et al.   JOURNAL OF NEUROCHEMISTRY

Glutathione: Overview of its protective roles, measurement, and biosynthesis

(2008) Henry Jay Forman et al.   MOLECULAR ASPECTS OF MEDICINE

GSH and analogs in antiviral therapy

(2008) Alessandra Fraternale et al.   MOLECULAR ASPECTS OF MEDICINE

Systemic infection and inflammation in acute CNS injury and chronic neurodegeneration: Underlying mechanisms

(2008) J.L. Teeling et al.   NEUROSCIENCE