The role of NADPH oxidases in infectious and inflammatory diseases

NOX-Dependent Signaling Dysregulation in Severe COVID-19: Clues to Effective Treatments

(2021) Simona Damiano et al.   Frontiers in Cellular and Infection Microbiology

USP7 Inhibition Alleviates H2O2-Induced Injury in Chondrocytes via Inhibiting NOX4/NLRP3 Pathway

(2021) Gang Liu et al.   Frontiers in Pharmacology

Regulation of Dual Oxidase Hydrogen Peroxide Synthesis Results in an Epithelial Respiratory Burst

(2021) Gregory E. Conner   Redox Biology

Nox3-derived superoxide in cochleae induces sensorineural hearing loss Mechanisms of Nox3-dependent hearing loss

(2021) Hiroaki Mohri et al.   JOURNAL OF NEUROSCIENCE

Xanthine oxidoreductase: One enzyme for multiple physiological tasks

(2021) Massimo Bortolotti et al.   Redox Biology

NOX4 regulates macrophage apoptosis resistance to induce fibrotic progression

(2021) Jennifer L. Larson-Casey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dual oxidase 1 promotes antiviral innate immunity

(2021) Demba Sarr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IgA potentiates NETosis in response to viral infection

(2021) Hannah D. Stacey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Is Low Alveolar Type II Cell SOD3 in the Lungs of Elderly Linked to the Observed Severity of COVID-19?

(2020) Ahmed S. Abouhashem et al.   ANTIOXIDANTS & REDOX SIGNALING

Endothelial cell infection and endotheliitis in COVID-19

(2020) Zsuzsanna Varga et al.   LANCET

Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19

(2020) Maximilian Ackermann et al.   NEW ENGLAND JOURNAL OF MEDICINE

Endogenous Deficiency of Glutathione as the Most Likely Cause of Serious Manifestations and Death in COVID-19 Patients

(2020) Alexey Polonikov   ACS Infectious Diseases

Localized Immunosuppression with Tannic Acid Encapsulation Delays Islet Allograft and Autoimmune-Mediated Rejection

(2020) Jessie M. Barra et al.   DIABETES

The role of NOX4 in pulmonary diseases

(2020) Zi‐Ming Li et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Severe COVID-19 infection associated with endothelial activation

(2020) Robert Escher et al.   THROMBOSIS RESEARCH

Confirmation of the high cumulative incidence of thrombotic complications in critically ill ICU patients with COVID-19: An updated analysis

(2020) F.A. Klok et al.   THROMBOSIS RESEARCH

The clinical implication of dynamic neutrophil to lymphocyte ratio and D-dimer in COVID-19: A retrospective study in Suzhou China

(2020) Jianhong Fu et al.   THROMBOSIS RESEARCH

Dual oxidase 1 limits the IFNγ-associated antitumor effect of macrophages

(2020) Lydia Meziani et al.   Journal for ImmunoTherapy of Cancer

The possible double‐edged sword effects of vitamin D on COVID‐19: A hypothesis

(2020) Ehsan Shojaeefar et al.   CELL BIOLOGY INTERNATIONAL

Epithelial-Derived Reactive Oxygen Species Enable AppBCX-Mediated Aerobic Respiration of Escherichia coli during Intestinal Inflammation

(2020) Rachael B. Chanin et al.   Cell Host & Microbe

Dexmedetomidine ameliorates renal ischemia reperfusion-mediated activation of the NLRP3 inflammasome in alveolar macrophages

(2020) Yingying Chen et al.   GENE

Nox2 activation in Covid-19

(2020) Francesco Violi et al.   Redox Biology

Anaerobic Respiration of NOX1-Derived Hydrogen Peroxide Licenses Bacterial Growth at the Colonic Surface

(2020) Brittany M. Miller et al.   Cell Host & Microbe

Cutting Edge: NOX2 NADPH Oxidase Controls Infection by an Intracellular Bacterial Pathogen through Limiting the Type 1 IFN Response

(2020) Jorge David Rojas Márquez et al.   JOURNAL OF IMMUNOLOGY

Induction of the reactive chlorine-responsive transcription factor RclR in Escherichia coli following ingestion by neutrophils

(2020) Andreas Königstorfer et al.   Pathogens and Disease

Essential Role of NADPH Oxidase–Dependent Production of Reactive Oxygen Species in Maintenance of Sustained B Cell Receptor Signaling and B Cell Proliferation

(2019) Yang-Yang Feng et al.   JOURNAL OF IMMUNOLOGY

Thyroid peroxidase as a dual active site enzyme: Focus on biosynthesis, hormonogenesis and thyroid disorders of autoimmunity and cancer

(2019) Marlena Godlewska et al.   BIOCHIMIE

NADPH oxidase 2-mediated NLRP1 inflammasome activation involves in neuronal senescence in hippocampal neurons in vitro

(2019) Tanzhen Xu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Tumoral NOX4 recruits M2 tumor-associated macrophages via ROS/PI3K signaling-dependent various cytokine production to promote NSCLC growth

(2019) Jiahao Zhang et al.   Redox Biology

Environmental microcystin targets the microbiome and increases the risk of intestinal inflammatory pathology via NOX2 in underlying murine model of Nonalcoholic Fatty Liver Disease

(2019) Sutapa Sarkar et al.   Scientific Reports

Inhibition of NOX2-NLRP1 signaling pathway protects against chronic glucocorticoids exposure-induced hippocampal neuronal damage

(2019) Lingling Sun et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

NOX4 activation is involved in ROS‐dependent Jurkat T cell death induced by Entamoeba histolytica

(2019) Young Ah Lee et al.   PARASITE IMMUNOLOGY

The phagocyte NOX2 NADPH oxidase in microbial killing and cell signaling

(2019) William M Nauseef   CURRENT OPINION IN IMMUNOLOGY

The NADPH Oxidase Family and Its Inhibitors

(2019) Mathieu Chocry et al.   ANTIOXIDANTS & REDOX SIGNALING

Lithium chloride promotes lipid accumulation through increased reactive oxygen species generation

(2019) Yunkyoung Lee et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Impaired inflammasome activation and bacterial clearance in G6PD deficiency due to defective NOX/p38 MAPK/AP-1 redox signaling

(2019) Wei-Chen Yen et al.   Redox Biology

The phagosome and redox control of antigen processing

(2018) Benjamin W. Ewanchuk et al.   FREE RADICAL BIOLOGY AND MEDICINE

Pathogenic Effects of IFIT2 and Interferon-β during Fatal Systemic Candida albicans Infection

(2018) Marcin Stawowczyk et al.   mBio

PKCδ-Mediated Nox2 Activation Promotes Fluid-Phase Pinocytosis of Antigens by Immature Dendritic Cells

(2018) Bhupesh Singla et al.   Frontiers in Immunology

Altered Humoral Immune Responses and IgG Subtypes in NOX2-Deficient Mice and Patients: A Key Role for NOX2 in Antigen-Presenting Cells

(2018) Julien Cachat et al.   Frontiers in Immunology

PKCδ stimulates macropinocytosis via activation of SSH1-cofilin pathway

(2018) Bhupesh Singla et al.   CELLULAR SIGNALLING

Heterogeneity of hypochlorous acid production in individual neutrophil phagosomes revealed by a rhodamine-based probe

(2018) Amelia M. Albrett et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Duox1 Regulates Primary B Cell Function under the Influence of IL-4 through BCR-Mediated Generation of Hydrogen Peroxide

(2018) Ryuichi Sugamata et al.   JOURNAL OF IMMUNOLOGY

The Nox1/Nox4 inhibitor attenuates acute lung injury induced by ischemia-reperfusion in mice

(2018) Yu Cui et al.   PLoS One

VAMP8-mediated NOX2 recruitment to endosomes is necessary for antigen release

(2017) Ilse Dingjan et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Contribution of guanine nucleotide exchange factor Vav2 to NLRP3 inflammasome activation in mouse podocytes during hyperhomocysteinemia

(2017) Sabena M. Conley et al.   FREE RADICAL BIOLOGY AND MEDICINE

Superoxide Production by NADPH Oxidase Intensifies Macrophage Antiviral Responses during Diabetogenic Coxsackievirus Infection

(2017) Ashley R. Burg et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Processing of Oxidized Peptides in Macrophages Regulates T Cell Activation and Development of Autoimmune Arthritis

(2017) Min Yang et al.   JOURNAL OF IMMUNOLOGY

NOX2 deficiency alters macrophage phenotype through an IL-10/STAT3 dependent mechanism: implications for traumatic brain injury

(2017) James P. Barrett et al.   Journal of Neuroinflammation

iNOS- and NOX1-dependent ROS production maintains bacterial homeostasis in the ileum of mice

(2017) C Matziouridou et al.   Mucosal Immunology

SOD2 Facilitates the Antiviral Innate Immune Response by Scavenging Reactive Oxygen Species

(2017) Wan Wang et al.   VIRAL IMMUNOLOGY

Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy

(2017) Eunice E. To et al.   Nature Communications

Neutrophils to the ROScue: Mechanisms of NADPH Oxidase Activation and Bacterial Resistance

(2017) Giang T. Nguyen et al.   Frontiers in Cellular and Infection Microbiology

Angiotensin-(1–7) Improves Liver Fibrosis by Regulating the NLRP3 Inflammasome via Redox Balance Modulation

(2016) Shuang-Ming Cai et al.   ANTIOXIDANTS & REDOX SIGNALING

A Reduction in Intracellular Reactive Oxygen Species Due to a Mutation in NCF4 Promotes Autoimmune Arthritis in Mice

(2016) Susann Winter et al.   ANTIOXIDANTS & REDOX SIGNALING

Duox2 is required for the transcription of pattern recognition receptors in acute viral lung infection: An interferon-independent regulatory mechanism

(2016) Seung-No Hong et al.   ANTIVIRAL RESEARCH

NOX4-dependent fatty acid oxidation promotes NLRP3 inflammasome activation in macrophages

(2016) Jong-Seok Moon et al.   NATURE MEDICINE

CRISPR/Cas9-mediated knockout of p22phox leads to loss of Nox1 and Nox4, but not Nox5 activity

(2016) Kim-Kristin Prior et al.   Redox Biology

Oxidation of Са2+-Binding Domain of NADPH Oxidase 5 (NOX5): Toward Understanding the Mechanism of Inactivation of NOX5 by ROS

(2016) Irina Yu Petrushanko et al.   PLoS One

Lipid peroxidation causes endosomal antigen release for cross-presentation

(2016) Ilse Dingjan et al.   Scientific Reports

The Induction of Pattern-Recognition Receptor Expression against Influenza A Virus through Duox2-Derived Reactive Oxygen Species in Nasal Mucosa

(2015) Hyun Jik Kim et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Lung epithelial NOX/DUOX and respiratory virus infections

(2015) Nathalie Grandvaux et al.   CLINICAL SCIENCE

NOX3-TARGETED THERAPIES FOR INNER EAR PATHOLOGIES

(2015) Francis Rousset et al.   CURRENT PHARMACEUTICAL DESIGN

Alkalinity of Neutrophil Phagocytic Vacuoles Is Modulated by HVCN1 and Has Consequences for Myeloperoxidase Activity

(2015) Adam P. Levine et al.   PLoS One

Reactive Oxygen Species Deficiency Induces Autoimmunity with Type 1 Interferon Signature

(2014) Tiina Kelkka et al.   ANTIOXIDANTS & REDOX SIGNALING

Nox4: A Hydrogen Peroxide-Generating Oxygen Sensor

(2014) Yukio Nisimoto et al.   BIOCHEMISTRY

Thiol-based redox switches

(2014) Bastian Groitl et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Loss of NADPH Oxidase–Derived Superoxide Skews Macrophage Phenotypes to Delay Type 1 Diabetes

(2014) Lindsey E. Padgett et al.   DIABETES

Hypothyroidism-associated missense mutation impairs NADPH oxidase activity and intracellular trafficking of Duox2

(2014) Ágnes Donkó et al.   FREE RADICAL BIOLOGY AND MEDICINE

NLRP3 inflammasome activation and interleukin-1β release in macrophages require calcium but are independent of calcium-activated NADPH oxidases

(2014) Balázs Rada et al.   INFLAMMATION RESEARCH

γ-Interferon-inducible Lysosomal Thiol Reductase (GILT) Maintains Phagosomal Proteolysis in Alternatively Activated Macrophages

(2014) Dale R. Balce et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The gut microbiota engages different signaling pathways to induce Duox2 expression in the ileum and colon epithelium

(2014) F Sommer et al.   Mucosal Immunology

Regulation of NADPH Oxidase 5 by Protein Kinase C Isoforms

(2014) Feng Chen et al.   PLoS One

Reactive Oxygen Species Induce Antiviral Innate Immune Response through IFN-λ Regulation in Human Nasal Epithelial Cells

(2013) Hyun Jik Kim et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Mucosal Reactive Oxygen Species Are Required for Antiviral Response: Role of Duox in Influenza A Virus Infection

(2013) Monika Strengert et al.   ANTIOXIDANTS & REDOX SIGNALING

IFNβ/TNFα synergism induces a non-canonical STAT2/IRF9-dependent pathway triggering a novel DUOX2 NADPH Oxidase-mediated airway antiviral response

(2013) Karin Fink et al.   CELL RESEARCH

NOXO1 phosphorylation on serine 154 is critical for optimal NADPH oxidase 1 assembly and activation

(2013) Maya Debbabi et al.   FASEB JOURNAL

Hypoxia downregulates PPARγ via an ERK1/2–NF-κB–Nox4-dependent mechanism in human pulmonary artery smooth muscle cells

(2013) Xianghuai Lu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Dual Oxidases Control Release of Hydrogen Peroxide by the Gastric Epithelium to Prevent Helicobacter felis Infection and Inflammation in Mice

(2013) Helmut Grasberger et al.   GASTROENTEROLOGY

Redox signaling regulates commensal-mediated mucosal homeostasis and restitution and requires formyl peptide receptor 1

(2013) A Alam et al.   Mucosal Immunology

Activation of caspase-1 by the NLRP3 inflammasome regulates the NADPH oxidase NOX2 to control phagosome function

(2013) Anna Sokolovska et al.   NATURE IMMUNOLOGY

Endosomal NADPH-oxidase is critical for induction of the tissue factor gene in monocytes and endothelial cells

(2013) Nadine Prinz et al.   THROMBOSIS AND HAEMOSTASIS

p47phox Directs Murine Macrophage Cell Fate Decisions

(2012) Liang Yi et al.   AMERICAN JOURNAL OF PATHOLOGY

Aquaporin 1, Nox1, and Ask1 mediate oxidant-induced smooth muscle cell hypertrophy

(2012) Imad Al Ghouleh et al.   CARDIOVASCULAR RESEARCH

siRNA-mediated knock-down of NOX3: therapy for hearing loss?

(2012) Leonard P. Rybak et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Nox4 Is a Protective Reactive Oxygen Species Generating Vascular NADPH Oxidase

(2012) Katrin Schröder et al.   CIRCULATION RESEARCH

Dysregulated TLR3-dependent signaling and innate immune activation in superoxide-deficient macrophages from nonobese diabetic mice

(2012) Maria C. Seleme et al.   FREE RADICAL BIOLOGY AND MEDICINE

Intra-tympanic delivery of short interfering RNA into the adult mouse cochlea

(2012) Naoki Oishi et al.   HEARING RESEARCH

Constitutive NADPH Oxidase 4 Activity Resides in the Composition of the B-loop and the Penultimate C Terminus

(2012) Katharina von Löhneysen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Annexin A1, formyl peptide receptor, and NOX1 orchestrate epithelial repair

(2012) Giovanna Leoni et al.   JOURNAL OF CLINICAL INVESTIGATION

Myeloperoxidase: a front-line defender against phagocytosed microorganisms

(2012) S. J. Klebanoff et al.   JOURNAL OF LEUKOCYTE BIOLOGY

A novel synthetic compound, 3-amino-3-(4-fluoro-phenyl)-1H-quinoline-2,4-dione, inhibits cisplatin-induced hearing loss by the suppression of reactive oxygen species: In vitro and in vivo study

(2012) Y.S. Shin et al.   NEUROSCIENCE

Dual Oxidase 2 is Essential for the Toll-Like Receptor 5-Mediated Inflammatory Response in Airway Mucosa

(2011) Jung-Hee Joo et al.   ANTIOXIDANTS & REDOX SIGNALING

Arterial flow reduces oxidative stress via an antioxidant response element and Oct-1 binding site within the NADPH oxidase 4 promoter in endothelial cells

(2011) Claudia Goettsch et al.   BASIC RESEARCH IN CARDIOLOGY

Nox5 Forms a Functional Oligomer Mediated by Self-Association of Its Dehydrogenase Domain

(2011) Tsukasa Kawahara et al.   BIOCHEMISTRY

Phagosomal proteolysis in dendritic cells is modulated by NADPH oxidase in a pH-independent manner

(2011) Joanna M Rybicka et al.   EMBO JOURNAL

Sp3 transcription factor is crucial for transcriptional activation of the human NOX4 gene

(2011) Masato Katsuyama et al.   FEBS Journal

Nrf2 regulates hyperoxia-induced Nox4 expression in human lung endothelium: Identification of functional antioxidant response elements on the Nox4 promoter

(2011) Srikanth Pendyala et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nox2 B-loop peptide, Nox2ds, specifically inhibits the NADPH oxidase Nox2

(2011) Gábor Csányi et al.   FREE RADICAL BIOLOGY AND MEDICINE

NOX5: from basic biology to signaling and disease

(2011) Karen Bedard et al.   FREE RADICAL BIOLOGY AND MEDICINE

The E-loop Is Involved in Hydrogen Peroxide Formation by the NADPH Oxidase Nox4

(2011) Ina Takac et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peroxide-dependent sulfenylation of the EGFR catalytic site enhances kinase activity

(2011) Candice E Paulsen et al.   Nature Chemical Biology

NADPH Oxidase-Mediated Redox Signaling: Roles in Cellular Stress Response, Stress Tolerance, and Tissue Repair

(2011) F. Jiang et al.   PHARMACOLOGICAL REVIEWS

PPARγ regulates hypoxia-induced Nox4 expression in human pulmonary artery smooth muscle cells through NF-κB

(2010) Xianghuai Lu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Phosphorylation of serine282 in NADPH oxidase activator 1 by Erk desensitizes EGF-induced ROS generation

(2010) Hyunjin Oh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Dual oxidase in the intestinal epithelium of zebrafish larvae has anti-bacterial properties

(2010) Maria Vega Flores et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Constitutive NADPH-Dependent Electron Transferase Activity of the Nox4 Dehydrogenase Domain

(2010) Yukio Nisimoto et al.   BIOCHEMISTRY

Inflammasome activation in NADPH oxidase defective mononuclear phagocytes from patients with chronic granulomatous disease

(2010) F. Meissner et al.   BLOOD

Upregulation of Nox4 by Hypertrophic Stimuli Promotes Apoptosis and Mitochondrial Dysfunction in Cardiac Myocytes

(2010) Tetsuro Ago et al.   CIRCULATION RESEARCH

NOX3-derived reactive oxygen species promote TNF-α-induced reductions in hepatocyte glycogen levels via a JNK pathway

(2010) Lanfang Li et al.   FEBS LETTERS

Urothelial cells produce hydrogen peroxide through the activation of Duox1

(2010) Ágnes Donkó et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Effects of Palmitate on Hepatic Insulin Resistance Are Mediated by NADPH Oxidase 3-derived Reactive Oxygen Species through JNK and p38MAPKPathways

(2010) Dan Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The NADPH Oxidase Subunit NOX4 Is a New Target Gene of the Hypoxia-inducible Factor-1

(2010) Isabel Diebold et al.   MOLECULAR BIOLOGY OF THE CELL

Molecular and Functional Characterization of Hv1 Proton Channel in Human Granulocytes

(2010) Gábor L. Petheő et al.   PLoS One

NADPH oxidase activity controls phagosomal proteolysis in macrophages through modulation of the lumenal redox environment of phagosomes

(2010) J. M. Rybicka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Nonphagocytic NADPH Oxidase Duox1 Mediates a Positive Feedback Loop During T Cell Receptor Signaling

(2010) J. Kwon et al.   Science Signaling

Requirement of NOX2 and Reactive Oxygen Species for Efficient RIG-I-Mediated Antiviral Response through Regulation of MAVS Expression

(2010) Anton Soucy-Faulkner et al.   PLoS Pathogens

JAK/STAT Signaling Pathway Regulates Nox1 and Nox4-Based NADPH Oxidase in Human Aortic Smooth Muscle Cells

(2009) Adrian Manea et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Nox proteins in signal transduction

(2009) David I. Brown et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Small GTPase Rac2 Controls Phagosomal Alkalinization and Antigen Crosspresentation Selectively in CD8+ Dendritic Cells

(2009) Ariel Savina et al.   IMMUNITY

Ce-Duox1/BLI-3 Generates Reactive Oxygen Species as a Protective Innate Immune Mechanism in Caenorhabditis elegans

(2009) V. Chavez et al.   INFECTION AND IMMUNITY

ATP-mediated Activation of the NADPH Oxidase DUOX1 Mediates Airway Epithelial Responses to Bacterial Stimuli

(2009) Agnes W. Boots et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hv1 proton channels are required for high-level NADPH oxidase-dependent superoxide production during the phagocyte respiratory burst

(2009) I. S. Ramsey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Voltage-gated proton channels maintain pH in human neutrophils during phagocytosis

(2009) D. Morgan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple TLRs activate EGFR via a signaling cascade to produce innate immune responses in airway epithelium

(2008) Jonathan L. Koff et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

A region N-terminal to the tandem SH3 domain of p47phoxplays a crucial role in the activation of the phagocyte NADPH oxidase

(2008) Masahiko Taura et al.   BIOCHEMICAL JOURNAL

NADPH oxidase controls phagosomal pH and antigen cross-presentation in human dendritic cells

(2008) A. R. Mantegazza et al.   BLOOD

Fc R-stimulated activation of the NADPH oxidase: phosphoinositide-binding protein p40phox regulates NADPH oxidase activity after enzyme assembly on the phagosome

(2008) W. Tian et al.   BLOOD

Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury

(2008) Yumiko Imai et al.   CELL

Positive regulation of the NADPH oxidase NOX4 promoter in vascular smooth muscle cells by E2F

(2008) Li Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nox1 is over-expressed in human colon cancers and correlates with activating mutations in K-Ras

(2008) Eunice Laurent et al.   INTERNATIONAL JOURNAL OF CANCER

Requirement of Reactive Oxygen Species-dependent Activation of ASK1-p38 MAPK Pathway for Extracellular ATP-induced Apoptosis in Macrophage

(2008) Takuya Noguchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of ROS signal transduction by NADPH oxidase 4 localization

(2008) Kai Chen et al.   JOURNAL OF CELL BIOLOGY

Phosphatidylinositol (4,5)-bisphosphate Modulates Nox5 Localization via an N-Terminal Polybasic Region

(2008) Tsukasa Kawahara et al.   MOLECULAR BIOLOGY OF THE CELL

Oncogenic Ras upregulates NADPH oxidase 1 gene expression through MEK-ERK-dependent phosphorylation of GATA-6

(2008) Y Adachi et al.   ONCOGENE

Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

(2008) C. Dostert et al.   SCIENCE

Genetics and immunopathology of chronic granulomatous disease

(2008) Marie José Stasia et al.   Seminars in Immunopathology

Hyperinflammation in chronic granulomatous disease and anti-inflammatory role of the phagocyte NADPH oxidase

(2008) Michela G. Schäppi et al.   Seminars in Immunopathology

Regulation of NOX1 expression by GATA, HNF-1α, and Cdx transcription factors

(2007) Anthony J. Valente et al.   FREE RADICAL BIOLOGY AND MEDICINE